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The map label for this gene is glmS [H]

Identifier: 93007221

GI number: 93007221

Start: 2946153

End: 2947997

Strand: Direct

Name: glmS [H]

Synonym: Pcryo_2397

Alternate gene names: 93007221

Gene position: 2946153-2947997 (Clockwise)

Preceding gene: 93007220

Following gene: 93007227

Centisome position: 96.28

GC content: 45.85

Gene sequence:

>1845_bases
ATGTGCGGAATAGTTGGAGCAGTGGCTGAGCGTAATATCGCCAATATCTTACTTGAGGGACTTAAGCGCCTAGAATATAG
AGGCTATGATTCTGCTGGTCTGACTGTCATTCGTGATGGCGAGCTCCACCGTGAGCGCCAAGTGGGTAAAGTTCAGGCCT
TAGTCGATGCCGTCGCAGTCAACCCAGAGTTTTTCGATGGTCATATTGGTATTGCGCATACACGCTGGGCAACGCATGGC
GAGCCGGCTCAGCGTAACGCCCATCCGCATGTTTCAGGCAAGATTGCTGTGGTACATAATGGTATCGTTGAAAACTACGC
CGAGCTAAAAGAAGAATTAATTGCCAAAGGGTACGAGTTTACCTCGCAAACCGATACCGAAGTCGTCGCGCATCTCATTA
ACGATATCTATAAAGCAACGCCTGACTTATTAGAAGCCGTTCGCACTGTCACTCCTTTGTTACATGGAGCATTTGCCCTT
GGCGTTATCCATGTTGATTGCCCAGAAGAGCTGATTACGGTACGTTTAGGCTCTCCTTTGGTGATTGGCGTCGGTATTGG
CGAAAACTTTATCGCCTCCGATCAATTGGCACTTTTACCAGTGACCAATCGTTTTATGTATCTAGAGGAAGGCGATATTG
CCCGATTAACGCGTAACAGTATTCAGGTTTACGCTGATGGTGTCGAGGTCACACGCCAAATCCATGAAATTGACGCAGCA
CAACACAATGCAGACAAGGGCGAATTTAAGCATTATATGCTCAAAGAAATCTACGAGCAGCCAGATGCTGTCGCTCGTAC
TCTCGAGATGGCATTAGATAATGATGAGCCAACTAAACTGCGTGATGATTTTCTGCAACGTCATGAAACGCAATTAAAAG
GCATTAAGCACGTACAAGTGATCGCTTGTGGTACTAGCTATCATTCAGGTTTGGTCGCAAAATATTGGTTTGAGAGTCTT
ATTCGTGTGCCTTGCTCAGTGGAAGTTGCCAGTGAGTTCCGTTATCGCAATCCAGTCGTTATTGATAACTCTTTAGTGAT
TTGTATTTCTCAGTCGGGCGAGACTGCTGATACTTTATCTGCACTACGTGATATTCAAAAACAGTCTCCTATTGGACTGG
TTAGTCTGGCATTGTGCAATGTGCCAACCTCATCATTGGTACGTGAAACGGATATCTTTTTACCAACGCTTGCCGGTCCC
GAGATTGGCGTGGCATCTACCAAAGCCTTTACTACTCAGCTTGCAGCACTGATGTTATTGTTATTAAAGGTAGGTGTGAC
CCAACAGCGCATGACTGATGAAAATTTGAGCACGCTGCTTAGTCAACTGCAACAACTACCGGGTCAGCTCCATGCCAGCT
TACACCTGGACGCGCCTATCAAGATCATGAGTGAGCATTTTGAATATAAGAAAAGCTGCTTATTCCTAGGTCGTGGTTTA
CAGTTCCCAATTGCTCTAGAAGGCGCATTAAAGTTAAAGGAAATCTCTTATATCCACGCTGAAGGCTATGCAGCAGGCGA
GCTGAAGCACGGACCATTGGCATTAGTGGATAAAGATATGCCTATCGTGGTGCTAGCCCCAAAAGACAGTATGTTTGATA
AGCTAAAAGCCAATATGCAAGAAGTACATGCCCGTCATGGTGAGTTGTTTGTCTTTGCAAGCGAATCCAGTCAAATGGTC
GCAGCAGATAGATTGCACGTGGTGTATGTGCCAGATGTTTGCGAAACGCTTGCGCCGATTGTTTATAGCGTGCCAGTACA
ATTGCTGTCATATCATGTCGCAGTAATGCGCGGTACAGACGTTGATCAGCCACGTAACCTAGCAAAATCAGTTACAGTCG
AATAA

Upstream 100 bases:

>100_bases
AATGATTTGTGGTGCTGCTTATTTATATTTATAGATTAACCAGACATCGTCATACATAGAAATACATAGAAATACTAATA
ATTAAATTTAAGGAATAGTT

Downstream 100 bases:

>100_bases
TGTTTACTAATTTATTTTATTTTTTGTCAGCGAGTAATAAAGTATCATATTAGACAATTCATTCTATTGACTCAACTATT
AGCCCTTGCTGTTGTTTAAT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MCGIVGAVAERNIANILLEGLKRLEYRGYDSAGLTVIRDGELHRERQVGKVQALVDAVAVNPEFFDGHIGIAHTRWATHG
EPAQRNAHPHVSGKIAVVHNGIVENYAELKEELIAKGYEFTSQTDTEVVAHLINDIYKATPDLLEAVRTVTPLLHGAFAL
GVIHVDCPEELITVRLGSPLVIGVGIGENFIASDQLALLPVTNRFMYLEEGDIARLTRNSIQVYADGVEVTRQIHEIDAA
QHNADKGEFKHYMLKEIYEQPDAVARTLEMALDNDEPTKLRDDFLQRHETQLKGIKHVQVIACGTSYHSGLVAKYWFESL
IRVPCSVEVASEFRYRNPVVIDNSLVICISQSGETADTLSALRDIQKQSPIGLVSLALCNVPTSSLVRETDIFLPTLAGP
EIGVASTKAFTTQLAALMLLLLKVGVTQQRMTDENLSTLLSQLQQLPGQLHASLHLDAPIKIMSEHFEYKKSCLFLGRGL
QFPIALEGALKLKEISYIHAEGYAAGELKHGPLALVDKDMPIVVLAPKDSMFDKLKANMQEVHARHGELFVFASESSQMV
AADRLHVVYVPDVCETLAPIVYSVPVQLLSYHVAVMRGTDVDQPRNLAKSVTVE

Sequences:

>Translated_614_residues
MCGIVGAVAERNIANILLEGLKRLEYRGYDSAGLTVIRDGELHRERQVGKVQALVDAVAVNPEFFDGHIGIAHTRWATHG
EPAQRNAHPHVSGKIAVVHNGIVENYAELKEELIAKGYEFTSQTDTEVVAHLINDIYKATPDLLEAVRTVTPLLHGAFAL
GVIHVDCPEELITVRLGSPLVIGVGIGENFIASDQLALLPVTNRFMYLEEGDIARLTRNSIQVYADGVEVTRQIHEIDAA
QHNADKGEFKHYMLKEIYEQPDAVARTLEMALDNDEPTKLRDDFLQRHETQLKGIKHVQVIACGTSYHSGLVAKYWFESL
IRVPCSVEVASEFRYRNPVVIDNSLVICISQSGETADTLSALRDIQKQSPIGLVSLALCNVPTSSLVRETDIFLPTLAGP
EIGVASTKAFTTQLAALMLLLLKVGVTQQRMTDENLSTLLSQLQQLPGQLHASLHLDAPIKIMSEHFEYKKSCLFLGRGL
QFPIALEGALKLKEISYIHAEGYAAGELKHGPLALVDKDMPIVVLAPKDSMFDKLKANMQEVHARHGELFVFASESSQMV
AADRLHVVYVPDVCETLAPIVYSVPVQLLSYHVAVMRGTDVDQPRNLAKSVTVE
>Mature_614_residues
MCGIVGAVAERNIANILLEGLKRLEYRGYDSAGLTVIRDGELHRERQVGKVQALVDAVAVNPEFFDGHIGIAHTRWATHG
EPAQRNAHPHVSGKIAVVHNGIVENYAELKEELIAKGYEFTSQTDTEVVAHLINDIYKATPDLLEAVRTVTPLLHGAFAL
GVIHVDCPEELITVRLGSPLVIGVGIGENFIASDQLALLPVTNRFMYLEEGDIARLTRNSIQVYADGVEVTRQIHEIDAA
QHNADKGEFKHYMLKEIYEQPDAVARTLEMALDNDEPTKLRDDFLQRHETQLKGIKHVQVIACGTSYHSGLVAKYWFESL
IRVPCSVEVASEFRYRNPVVIDNSLVICISQSGETADTLSALRDIQKQSPIGLVSLALCNVPTSSLVRETDIFLPTLAGP
EIGVASTKAFTTQLAALMLLLLKVGVTQQRMTDENLSTLLSQLQQLPGQLHASLHLDAPIKIMSEHFEYKKSCLFLGRGL
QFPIALEGALKLKEISYIHAEGYAAGELKHGPLALVDKDMPIVVLAPKDSMFDKLKANMQEVHARHGELFVFASESSQMV
AADRLHVVYVPDVCETLAPIVYSVPVQLLSYHVAVMRGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=691, Percent_Identity=37.9160636758321, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI205277386, Length=689, Percent_Identity=37.4455732946299, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI29570798, Length=255, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1790167, Length=622, Percent_Identity=55.9485530546624, Blast_Score=679, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539970, Length=434, Percent_Identity=38.7096774193548, Blast_Score=277, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17532897, Length=433, Percent_Identity=37.8752886836028, Blast_Score=276, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17532899, Length=433, Percent_Identity=37.8752886836028, Blast_Score=275, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6322745, Length=447, Percent_Identity=38.255033557047, Blast_Score=284, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6323731, Length=433, Percent_Identity=30.2540415704388, Blast_Score=200, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=39.5121951219512, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21357745, Length=694, Percent_Identity=36.0230547550432, Blast_Score=404, Evalue=1e-112,
Organism=Drosophila melanogaster, GI28573187, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67639; Mature: 67639

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAERNIANILLEGLKRLEYRGYDSAGLTVIRDGELHRERQVGKVQALVDAVAV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHC
NPEFFDGHIGIAHTRWATHGEPAQRNAHPHVSGKIAVVHNGIVENYAELKEELIAKGYEF
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCC
TSQTDTEVVAHLINDIYKATPDLLEAVRTVTPLLHGAFALGVIHVDCPEELITVRLGSPL
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHEEEECCCCE
VIGVGIGENFIASDQLALLPVTNRFMYLEEGDIARLTRNSIQVYADGVEVTRQIHEIDAA
EEEEECCCCCCCCCCEEEEEECCEEEEEECCCHHHHHHCCEEEEECHHHHHHHHHHHHHH
QHNADKGEFKHYMLKEIYEQPDAVARTLEMALDNDEPTKLRDDFLQRHETQLKGIKHVQV
HCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
IACGTSYHSGLVAKYWFESLIRVPCSVEVASEFRYRNPVVIDNSLVICISQSGETADTLS
EEECCCCCCCHHHHHHHHHHHCCCCCEEHHHHHCCCCCEEECCCEEEEEECCCCCHHHHH
ALRDIQKQSPIGLVSLALCNVPTSSLVRETDIFLPTLAGPEIGVASTKAFTTQLAALMLL
HHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHH
LLKVGVTQQRMTDENLSTLLSQLQQLPGQLHASLHLDAPIKIMSEHFEYKKSCLFLGRGL
HHHHCCCHHHHCHHHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
QFPIALEGALKLKEISYIHAEGYAAGELKHGPLALVDKDMPIVVLAPKDSMFDKLKANMQ
CCCEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHH
EVHARHGELFVFASESSQMVAADRLHVVYVPDVCETLAPIVYSVPVQLLSYHVAVMRGTD
HHHHCCCCEEEEECCCCCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEECCC
VDQPRNLAKSVTVE
CCCHHHHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAERNIANILLEGLKRLEYRGYDSAGLTVIRDGELHRERQVGKVQALVDAVAV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHC
NPEFFDGHIGIAHTRWATHGEPAQRNAHPHVSGKIAVVHNGIVENYAELKEELIAKGYEF
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCC
TSQTDTEVVAHLINDIYKATPDLLEAVRTVTPLLHGAFALGVIHVDCPEELITVRLGSPL
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHEEEECCCCE
VIGVGIGENFIASDQLALLPVTNRFMYLEEGDIARLTRNSIQVYADGVEVTRQIHEIDAA
EEEEECCCCCCCCCCEEEEEECCEEEEEECCCHHHHHHCCEEEEECHHHHHHHHHHHHHH
QHNADKGEFKHYMLKEIYEQPDAVARTLEMALDNDEPTKLRDDFLQRHETQLKGIKHVQV
HCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
IACGTSYHSGLVAKYWFESLIRVPCSVEVASEFRYRNPVVIDNSLVICISQSGETADTLS
EEECCCCCCCHHHHHHHHHHHCCCCCEEHHHHHCCCCCEEECCCEEEEEECCCCCHHHHH
ALRDIQKQSPIGLVSLALCNVPTSSLVRETDIFLPTLAGPEIGVASTKAFTTQLAALMLL
HHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHH
LLKVGVTQQRMTDENLSTLLSQLQQLPGQLHASLHLDAPIKIMSEHFEYKKSCLFLGRGL
HHHHCCCHHHHCHHHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
QFPIALEGALKLKEISYIHAEGYAAGELKHGPLALVDKDMPIVVLAPKDSMFDKLKANMQ
CCCEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHH
EVHARHGELFVFASESSQMVAADRLHVVYVPDVCETLAPIVYSVPVQLLSYHVAVMRGTD
HHHHCCCCEEEEECCCCCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEECCC
VDQPRNLAKSVTVE
CCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA