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The map label for this gene is mraY [H]

Identifier: 93007199

GI number: 93007199

Start: 2919545

End: 2920663

Strand: Reverse

Name: mraY [H]

Synonym: Pcryo_2375

Alternate gene names: 93007199

Gene position: 2920663-2919545 (Counterclockwise)

Preceding gene: 93007200

Following gene: 93007198

Centisome position: 95.45

GC content: 46.47

Gene sequence:

>1119_bases
GTGTTAGTTTGGTTGTTTAGCTGGCTTGGTCATTATTATGCCCCGTTTTATGCGGTTTCTTCTTTGACGCTGCGCGCGTT
ACTGGCGGTCGTTACCGCCCTTGCTTTTAGCATGGTTTTTGGTAATCGCGTTATTCGACGTTTGCGTGCACTTAAGTACG
GTCAGGCGATTCGTAATGATGGACCACAGTCGCATTTGGTCAAAACTGGCACCCCGACCATGGGTGGGGTGCTGATTTTG
AGCGCAATTGGGGTATCAACCTTACTTTGGGCGCGTTTGAATAATCCGTATGTCTGGATTTTGCTCATTGTCATGATTAT
CTTTGGTGCGGTAGGCTGGGCGGATGATTGGCTCAAAATTAAATATAAGAACCCAAAAGGTCTAATTGCTCGCAAAAAAT
ACTTTTGGCTATCCATGGGTGCATTATTCGTCGGCATTTCTTTATATTATATTGCCACACTGCAGCCAGATATTGCGACG
ACTCGCGAGATGCAGGATTTATTAATACCTATCTTTAAAGATTGGATGATTCCATTTTCGGCAGTGCCGTTTGGTATTGG
CTTTATTATCTTTACTTACTTTGTGATTAATGGCGCCTCTAACGCGGTCAATTTAACTGATGGCTTGGATGGCTTGGCGA
TTTTGCCAGTGGTCTTGGTTGCTGCAGGCTTGGGCGCGATGGCATATGTCTCTGGTGACGTACGCTTTGCGGATTACTTG
CACGTACCTTATATTGCCTACAATTCTGAGGTGATTATTGTCTGTGGCGCGATGATTGGCGCAGGGCTTGGCTTTTTATG
GTTTAACGCCCATCCAGCGCAAGTGTTTATGGGTGATGTGGGTGCGCTGTCACTGGGCGCAATGCTCGGTACCATTGCGG
TAATGACCCGTCAAGAAATCGCTTTCGCAATTATGGGCGGACTGTTCGTTGCAGAAGCATTGTCGGTAATGCTACAGGTT
GGCTCATATAAGCTACGCAAAAAGCGCGTCTTTCGTATGGCACCGCTGCATCACCATTTTGAAGAGATTGGCTGGAAAGA
AACCCAAGTGGTCGCAAGGTTTTGGATTATCGCCATTATCTTGGTTATCCTTGGCTTGATGACGTTAAAGCTGCGTTAG

Upstream 100 bases:

>100_bases
TTTGCAAGCGCAGCAGGCGCAACCTTGTACGGTGTTGTTTAAAGGTTCTCGTTCCATGGAAATGGAAACACTTATCAATG
CGCTAGTCGAGGAGTAGGCA

Downstream 100 bases:

>100_bases
AACAGTAACTCAGATTAATCTCGATATTCTTCGTTAAAAAGCCATCTCAACAAGTTTGAGATGGCTTTTTTGTTTCCCAT
ACTATCTTTTCTCATACCTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLVWLFSWLGHYYAPFYAVSSLTLRALLAVVTALAFSMVFGNRVIRRLRALKYGQAIRNDGPQSHLVKTGTPTMGGVLIL
SAIGVSTLLWARLNNPYVWILLIVMIIFGAVGWADDWLKIKYKNPKGLIARKKYFWLSMGALFVGISLYYIATLQPDIAT
TREMQDLLIPIFKDWMIPFSAVPFGIGFIIFTYFVINGASNAVNLTDGLDGLAILPVVLVAAGLGAMAYVSGDVRFADYL
HVPYIAYNSEVIIVCGAMIGAGLGFLWFNAHPAQVFMGDVGALSLGAMLGTIAVMTRQEIAFAIMGGLFVAEALSVMLQV
GSYKLRKKRVFRMAPLHHHFEEIGWKETQVVARFWIIAIILVILGLMTLKLR

Sequences:

>Translated_372_residues
MLVWLFSWLGHYYAPFYAVSSLTLRALLAVVTALAFSMVFGNRVIRRLRALKYGQAIRNDGPQSHLVKTGTPTMGGVLIL
SAIGVSTLLWARLNNPYVWILLIVMIIFGAVGWADDWLKIKYKNPKGLIARKKYFWLSMGALFVGISLYYIATLQPDIAT
TREMQDLLIPIFKDWMIPFSAVPFGIGFIIFTYFVINGASNAVNLTDGLDGLAILPVVLVAAGLGAMAYVSGDVRFADYL
HVPYIAYNSEVIIVCGAMIGAGLGFLWFNAHPAQVFMGDVGALSLGAMLGTIAVMTRQEIAFAIMGGLFVAEALSVMLQV
GSYKLRKKRVFRMAPLHHHFEEIGWKETQVVARFWIIAIILVILGLMTLKLR
>Mature_372_residues
MLVWLFSWLGHYYAPFYAVSSLTLRALLAVVTALAFSMVFGNRVIRRLRALKYGQAIRNDGPQSHLVKTGTPTMGGVLIL
SAIGVSTLLWARLNNPYVWILLIVMIIFGAVGWADDWLKIKYKNPKGLIARKKYFWLSMGALFVGISLYYIATLQPDIAT
TREMQDLLIPIFKDWMIPFSAVPFGIGFIIFTYFVINGASNAVNLTDGLDGLAILPVVLVAAGLGAMAYVSGDVRFADYL
HVPYIAYNSEVIIVCGAMIGAGLGFLWFNAHPAQVFMGDVGALSLGAMLGTIAVMTRQEIAFAIMGGLFVAEALSVMLQV
GSYKLRKKRVFRMAPLHHHFEEIGWKETQVVARFWIIAIILVILGLMTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=372, Percent_Identity=54.0322580645161, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 41149; Mature: 41149

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVWLFSWLGHYYAPFYAVSSLTLRALLAVVTALAFSMVFGNRVIRRLRALKYGQAIRND
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPQSHLVKTGTPTMGGVLILSAIGVSTLLWARLNNPYVWILLIVMIIFGAVGWADDWLKI
CCHHCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEE
KYKNPKGLIARKKYFWLSMGALFVGISLYYIATLQPDIATTREMQDLLIPIFKDWMIPFS
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCHH
AVPFGIGFIIFTYFVINGASNAVNLTDGLDGLAILPVVLVAAGLGAMAYVSGDVRFADYL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCCHHHHCCCCCEEEHEE
HVPYIAYNSEVIIVCGAMIGAGLGFLWFNAHPAQVFMGDVGALSLGAMLGTIAVMTRQEI
ECCEEEECCCEEEEEHHHHHCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AFAIMGGLFVAEALSVMLQVGSYKLRKKRVFRMAPLHHHFEEIGWKETQVVARFWIIAII
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LVILGLMTLKLR
HHHHHHHHHCCC
>Mature Secondary Structure
MLVWLFSWLGHYYAPFYAVSSLTLRALLAVVTALAFSMVFGNRVIRRLRALKYGQAIRND
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPQSHLVKTGTPTMGGVLILSAIGVSTLLWARLNNPYVWILLIVMIIFGAVGWADDWLKI
CCHHCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEE
KYKNPKGLIARKKYFWLSMGALFVGISLYYIATLQPDIATTREMQDLLIPIFKDWMIPFS
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCHH
AVPFGIGFIIFTYFVINGASNAVNLTDGLDGLAILPVVLVAAGLGAMAYVSGDVRFADYL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCCHHHHCCCCCEEEHEE
HVPYIAYNSEVIIVCGAMIGAGLGFLWFNAHPAQVFMGDVGALSLGAMLGTIAVMTRQEI
ECCEEEECCCEEEEEHHHHHCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AFAIMGGLFVAEALSVMLQVGSYKLRKKRVFRMAPLHHHFEEIGWKETQVVARFWIIAII
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LVILGLMTLKLR
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA