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The map label for this gene is pepE [H]

Identifier: 93007097

GI number: 93007097

Start: 2791113

End: 2792930

Strand: Reverse

Name: pepE [H]

Synonym: Pcryo_2273

Alternate gene names: 93007097

Gene position: 2792930-2791113 (Counterclockwise)

Preceding gene: 93007098

Following gene: 93007093

Centisome position: 91.28

GC content: 46.59

Gene sequence:

>1818_bases
ATGAATAAACAAGCCATTCATGATCGTATCGAGAGCTTACGTCAAACCCTAGCAGCACAAGACCTGACAGCGATTATTGT
CCCTTCTGCTGATCCGCATCTGTCTGAGTATTTACCAGAATATTGGCAGGCGAGGCTTTGGTTGTCAGGCTTTACCGGTT
CGGTCGGTACATTGGTCGTTACCGCTGACTTTGCTGGTCTGTGGACCGACAGCCGCTACTGGGTACATGCAGCTGAGCAG
TTGGATGGCACGGGTATTACTTTAGAGAAGCTAGCACCGGGTCAGCCAAACCATATCGATTGGTTGGCTACGCATTTGGC
GGAAGGTGATAGCGTGGCAGTCGATGGCAATGTACTGTCTATCGCTGAGCAAGATCGCTTGCTTGATGCCTTTGAAGCCA
ATGATATTACCTTAATTACTGAGCGTGATCTATTGACGGAAGTATGGACTGACCGTCCAGCATTGCCAGCAGCCAGTTTA
TATGTACATGATGCACAGTTTTTAGCGCAGTCTGCTATCGACAAACTTGTCGCCGTCCGTGTGGGTATGGCAGAGGCAGG
GGCGACGCATCATCTGCTCTCGAGCTTAGATGATATTGCTTGGCTGACCAACTTACGCGGCGCTGATGTTGATTATAATC
CTGTGTTTTTGGCACATATGCTCATTAGCGAAAACGACGCGACATTGTTTATTGATAATAATAAAGTCAATAGCGAGATA
GCACAAAGCTTGAAAGATAGCGGTATCGCAATTGCTGATTATGAGGCAGTGCAAGACGCATTGGGTACGCTCACAGCCAA
TGACTTATTGCTATTAGACCCAAGTAAAGTGGCAGTGGGTACGCTATCTAAAATGGCCGATGGCGTAGGTTTTATTGAGC
AAATGGCGCCAAGTACTTTGCTAAAATCGGTTAAATCTGACGCTGACATCGATCATGTACGTGAAGCGATGCGTCAAGAT
GGCGCAGCATTATGTGAGTTTTTTGCCACCTTTGAGCAGCGTTTAGCAGACGGTGAGCATTTAAGCGAGCTGGATGTTGA
TAGTATGCTGATCGAGGTACGTAGTCAGCAGCCACATTATGTGTCGCCAAGTTTCCCCACTATCGCAGGTTTCAATGAAA
ACGGTGCTTTGCCGCATTACCGCGCAACACCAGAAAAATTCAGCTATTTAGATGTAAATGAAGGCGAAGGCGGACTGCTA
CTGATTGATTCAGGTGCTCAATATCAAAACGGCACCACAGATATCACCCGGGTGGTTGGCATCGGTCAAGTAAGCACGGA
ACACAAACGCGACTTTACCACTGTACTTAAAGCACATATTGCTTTAGCAAAAGCACATTTTCCTGATGGTATTGCCTCAC
CACTGATTGATGCGATTTGCCGTGCGCCACTATGGCAAGCTCAAATGGATTATGGTCACGGTACGGGTCATGGCGTTGGT
TACTTCCTCAATGTCCATGAAGGTCCACAAGTGATTGCTTATAGTGCCAGTACGCCAAAAGAGCGCGCGATGAAAGAAGG
TATGATATCTAGTAATGAGCCGGGTCTATACCGCGAAGGTAAGTGGGGGATCCGTATCGAAAACTTGATGGTTAATAAAC
GTGTTTCTCATCCAGTAGAGACGGAATTTGGTAATTTCCTTAATTTTGAGACTGTTACTTACTGCCCAATTGATACGCGT
TTGATTGAGCCATCATTATTAAGTCAAGTAGAGGTCGATTGGCTGAATGACTATCATCGCCAAGTATATGCAGAGCTAAA
AAATCGCGTCGATGGCGCAGCACTTGACTGGCTAACCGAGCGTACGCAAGCCATATAA

Upstream 100 bases:

>100_bases
CAATTTCTCAAATAAGACGGCTATCCATAGTCGCCTCACGTTATTTTTTAAACGCTGATTTTTAAATACTAATTTTTAAA
CACTCATAAGGAATTACCTA

Downstream 100 bases:

>100_bases
ACATTGCTCATTTTTAAGCAAGCATAAAAAAGCCCCGTAAATATTTATGGGGCTTTTTTTTGTTCAGAGAATGCGTTTAG
TTTTTTGGAAGATTACCGTT

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MNKQAIHDRIESLRQTLAAQDLTAIIVPSADPHLSEYLPEYWQARLWLSGFTGSVGTLVVTADFAGLWTDSRYWVHAAEQ
LDGTGITLEKLAPGQPNHIDWLATHLAEGDSVAVDGNVLSIAEQDRLLDAFEANDITLITERDLLTEVWTDRPALPAASL
YVHDAQFLAQSAIDKLVAVRVGMAEAGATHHLLSSLDDIAWLTNLRGADVDYNPVFLAHMLISENDATLFIDNNKVNSEI
AQSLKDSGIAIADYEAVQDALGTLTANDLLLLDPSKVAVGTLSKMADGVGFIEQMAPSTLLKSVKSDADIDHVREAMRQD
GAALCEFFATFEQRLADGEHLSELDVDSMLIEVRSQQPHYVSPSFPTIAGFNENGALPHYRATPEKFSYLDVNEGEGGLL
LIDSGAQYQNGTTDITRVVGIGQVSTEHKRDFTTVLKAHIALAKAHFPDGIASPLIDAICRAPLWQAQMDYGHGTGHGVG
YFLNVHEGPQVIAYSASTPKERAMKEGMISSNEPGLYREGKWGIRIENLMVNKRVSHPVETEFGNFLNFETVTYCPIDTR
LIEPSLLSQVEVDWLNDYHRQVYAELKNRVDGAALDWLTERTQAI

Sequences:

>Translated_605_residues
MNKQAIHDRIESLRQTLAAQDLTAIIVPSADPHLSEYLPEYWQARLWLSGFTGSVGTLVVTADFAGLWTDSRYWVHAAEQ
LDGTGITLEKLAPGQPNHIDWLATHLAEGDSVAVDGNVLSIAEQDRLLDAFEANDITLITERDLLTEVWTDRPALPAASL
YVHDAQFLAQSAIDKLVAVRVGMAEAGATHHLLSSLDDIAWLTNLRGADVDYNPVFLAHMLISENDATLFIDNNKVNSEI
AQSLKDSGIAIADYEAVQDALGTLTANDLLLLDPSKVAVGTLSKMADGVGFIEQMAPSTLLKSVKSDADIDHVREAMRQD
GAALCEFFATFEQRLADGEHLSELDVDSMLIEVRSQQPHYVSPSFPTIAGFNENGALPHYRATPEKFSYLDVNEGEGGLL
LIDSGAQYQNGTTDITRVVGIGQVSTEHKRDFTTVLKAHIALAKAHFPDGIASPLIDAICRAPLWQAQMDYGHGTGHGVG
YFLNVHEGPQVIAYSASTPKERAMKEGMISSNEPGLYREGKWGIRIENLMVNKRVSHPVETEFGNFLNFETVTYCPIDTR
LIEPSLLSQVEVDWLNDYHRQVYAELKNRVDGAALDWLTERTQAI
>Mature_605_residues
MNKQAIHDRIESLRQTLAAQDLTAIIVPSADPHLSEYLPEYWQARLWLSGFTGSVGTLVVTADFAGLWTDSRYWVHAAEQ
LDGTGITLEKLAPGQPNHIDWLATHLAEGDSVAVDGNVLSIAEQDRLLDAFEANDITLITERDLLTEVWTDRPALPAASL
YVHDAQFLAQSAIDKLVAVRVGMAEAGATHHLLSSLDDIAWLTNLRGADVDYNPVFLAHMLISENDATLFIDNNKVNSEI
AQSLKDSGIAIADYEAVQDALGTLTANDLLLLDPSKVAVGTLSKMADGVGFIEQMAPSTLLKSVKSDADIDHVREAMRQD
GAALCEFFATFEQRLADGEHLSELDVDSMLIEVRSQQPHYVSPSFPTIAGFNENGALPHYRATPEKFSYLDVNEGEGGLL
LIDSGAQYQNGTTDITRVVGIGQVSTEHKRDFTTVLKAHIALAKAHFPDGIASPLIDAICRAPLWQAQMDYGHGTGHGVG
YFLNVHEGPQVIAYSASTPKERAMKEGMISSNEPGLYREGKWGIRIENLMVNKRVSHPVETEFGNFLNFETVTYCPIDTR
LIEPSLLSQVEVDWLNDYHRQVYAELKNRVDGAALDWLTERTQAI

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=633, Percent_Identity=35.7030015797788, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI264681565, Length=633, Percent_Identity=33.8072669826224, Blast_Score=334, Evalue=1e-91,
Organism=Homo sapiens, GI93141226, Length=612, Percent_Identity=32.6797385620915, Blast_Score=319, Evalue=4e-87,
Organism=Escherichia coli, GI1788728, Length=175, Percent_Identity=32, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509539, Length=601, Percent_Identity=33.6106489184692, Blast_Score=328, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI25149105, Length=631, Percent_Identity=27.4167987321712, Blast_Score=243, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6322999, Length=658, Percent_Identity=32.0668693009119, Blast_Score=306, Evalue=7e-84,
Organism=Drosophila melanogaster, GI17137632, Length=596, Percent_Identity=33.7248322147651, Blast_Score=320, Evalue=3e-87,
Organism=Drosophila melanogaster, GI161078230, Length=636, Percent_Identity=28.1446540880503, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI21357287, Length=636, Percent_Identity=28.1446540880503, Blast_Score=244, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 66500; Mature: 66500

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQAIHDRIESLRQTLAAQDLTAIIVPSADPHLSEYLPEYWQARLWLSGFTGSVGTLVV
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCEEEEE
TADFAGLWTDSRYWVHAAEQLDGTGITLEKLAPGQPNHIDWLATHLAEGDSVAVDGNVLS
EECCCCCCCCCCEEEEEHHHCCCCCEEHHHCCCCCCCHHHHHHHHHCCCCCEEECCCEEE
IAEQDRLLDAFEANDITLITERDLLTEVWTDRPALPAASLYVHDAQFLAQSAIDKLVAVR
EHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHH
VGMAEAGATHHLLSSLDDIAWLTNLRGADVDYNPVFLAHMLISENDATLFIDNNKVNSEI
HCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEHHHCCCCCCEEEEECCCCHHHH
AQSLKDSGIAIADYEAVQDALGTLTANDLLLLDPSKVAVGTLSKMADGVGFIEQMAPSTL
HHHHHHCCCEEEHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKSVKSDADIDHVREAMRQDGAALCEFFATFEQRLADGEHLSELDVDSMLIEVRSQQPHY
HHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCC
VSPSFPTIAGFNENGALPHYRATPEKFSYLDVNEGEGGLLLIDSGAQYQNGTTDITRVVG
CCCCCCEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCHHHHHEE
IGQVSTEHKRDFTTVLKAHIALAKAHFPDGIASPLIDAICRAPLWQAQMDYGHGTGHGVG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEE
YFLNVHEGPQVIAYSASTPKERAMKEGMISSNEPGLYREGKWGIRIENLMVNKRVSHPVE
EEEEECCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEECCCCCEEEEEEEECCCCCCCCH
TEFGNFLNFETVTYCPIDTRLIEPSLLSQVEVDWLNDYHRQVYAELKNRVDGAALDWLTE
HHHCCCCCCCEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RTQAI
HHHCC
>Mature Secondary Structure
MNKQAIHDRIESLRQTLAAQDLTAIIVPSADPHLSEYLPEYWQARLWLSGFTGSVGTLVV
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCEEEEE
TADFAGLWTDSRYWVHAAEQLDGTGITLEKLAPGQPNHIDWLATHLAEGDSVAVDGNVLS
EECCCCCCCCCCEEEEEHHHCCCCCEEHHHCCCCCCCHHHHHHHHHCCCCCEEECCCEEE
IAEQDRLLDAFEANDITLITERDLLTEVWTDRPALPAASLYVHDAQFLAQSAIDKLVAVR
EHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHH
VGMAEAGATHHLLSSLDDIAWLTNLRGADVDYNPVFLAHMLISENDATLFIDNNKVNSEI
HCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEHHHCCCCCCEEEEECCCCHHHH
AQSLKDSGIAIADYEAVQDALGTLTANDLLLLDPSKVAVGTLSKMADGVGFIEQMAPSTL
HHHHHHCCCEEEHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKSVKSDADIDHVREAMRQDGAALCEFFATFEQRLADGEHLSELDVDSMLIEVRSQQPHY
HHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCC
VSPSFPTIAGFNENGALPHYRATPEKFSYLDVNEGEGGLLLIDSGAQYQNGTTDITRVVG
CCCCCCEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCHHHHHEE
IGQVSTEHKRDFTTVLKAHIALAKAHFPDGIASPLIDAICRAPLWQAQMDYGHGTGHGVG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEE
YFLNVHEGPQVIAYSASTPKERAMKEGMISSNEPGLYREGKWGIRIENLMVNKRVSHPVE
EEEEECCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEECCCCCEEEEEEEECCCCCCCCH
TEFGNFLNFETVTYCPIDTRLIEPSLLSQVEVDWLNDYHRQVYAELKNRVDGAALDWLTE
HHHCCCCCCCEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RTQAI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]