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The map label for this gene is yclF [H]

Identifier: 93007098

GI number: 93007098

Start: 2793292

End: 2794854

Strand: Reverse

Name: yclF [H]

Synonym: Pcryo_2274

Alternate gene names: 93007098

Gene position: 2794854-2793292 (Counterclockwise)

Preceding gene: 93007099

Following gene: 93007097

Centisome position: 91.34

GC content: 43.95

Gene sequence:

>1563_bases
ATGAATATAGAATCAAAATCAGAGGTGAGTGCTGCCGAATTGGCATCGCTAGAAAACGGCTTTATGGGACATCCTAAGCC
GCTACGCCCGTTATTTTTCACTGAAATGTGGGAGCGTTTTTCTTATTATAGTATCCGTCCGCTACTGGTATTGTTTATGG
TAGCGACTGTCGGTAGTGGGGGTTTTGGCTTTGATGAAGTGACTGCCTCTGCCATTTATGGTATTTTTGCCGGTTCGTTG
TATTTAGCAGCCGTGCCGGGCGGTTGGCTAGCTGACAATTGGCTGGGTCAAGAGCGTGCGCTATGGTGGGGCAGTATTAT
TATTGCTTTGGGTCATTTGTGTATCGCGCTTTCTGCTATGTTCGGTATGACGCTGTTCTTTATGGGGCTCATCTGTATCG
TCTTGGGTTCAGGCTTGTTTAAAACCTGTATCTCAGTGATGGTTGGTGCCTTATACCCTAAGGGCGATTCGCGCCGCGAT
GGTGGATTTACTTTATTTTATATGGGTATCAATATTGGCGCGCTATTGGCAGCACTGATTGTGGGTGTATTTAAAGAAAA
AGGGATGTGGCATATAGGTTTTGGCGTTGGTGGACTTGGTATGTTGGCTTCGCTAATCATTTACCGCTTTTCTGCTAAAA
AGACGTTAAATCGTTATGCCAGTGCCAAAAACATCACCCCTGAATGGGAGCAATCGACAGGACTGTTTAAAAACGTCGGT
CAGTGGGTTGCAGGATTCTTAGCTTTGCTAGTTGCCATTGTGATTTTAGTATCCACTGGTATCATGCCATTTAACCCTGA
AATGGTCGCAGAATATATGACTTATGTCATTGCTGCAGTGGTCATCTTATATTTTGCAGTAATGGCTATTTCACCAAGAC
TGGATAAAACAGATAAGCTGCGCTTGTTGATTTGCTTTATTTTGATTATTGGCTCGACGCTATTTTGGTCAAGTTTTGAG
CAGCAACCAACGTCTTTTAACTTGTTTGCCGATCGCTATACAGATCTAAATGTTTTAGGGTTTGAAGTACCCAGTATCTG
GTTTCAATCATTGAATCCGTTGTTTATCTTAATATTAGCGCCTATAGCTAGTATTTTATGGGTCAAGCTTGGCAATCGAG
GTCTTGAGCCAAGTAGTATGACGAAGTTTGCGCTTGGTATGTTGCTTGCGGCTGCCGGTTTTGCCTTGATGATATTTGCA
TCAAAAAGCATCTTAACCGCTGATGGCGGCTTGGCATCACCTTTATGGTTGGTTGGTAGTCTATTACTACTGACGCTTGG
TGAGTTGGCACTGAGCCCTGTTGGGTTGTCTGCTATGACGAAGCTTGCGCCAAAAGGTATGCAAGGGCAGATGATGGGGC
TGTTCTTTGCTTCTGTTGCACTGGGCAACTTAGTTGCGGCATTCTTTGGTGGTCATGTCTCAGCAGATAAGATTGAAGGA
TTACCCGGATTGTTTACCACTATGACTGTCTTTTTGGTAGTAACGGCAGTTATCTTGCTATTATTGGCAAAACCTATCAA
TAATATGCTCAAACAAAGCGAGCATGCGGATCAAGCCAGCTAG

Upstream 100 bases:

>100_bases
TGCTTCCGAGCAGGTGAAACAATATTGCGCCTATAAAACCACTGACTAAAAGAATTAGGAATTGGGGCATTATCTAAGTG
GAATTTAAGGGAATAGATTT

Downstream 100 bases:

>100_bases
ATAACCAGTTATTGATTAGAAGTGGTCCAAGTCAGTGACTGATGATAAGACGTGTTACCATTATGGGTAGCATGTCTTAT
TTTTTAACTTGCTAAGATAT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MNIESKSEVSAAELASLENGFMGHPKPLRPLFFTEMWERFSYYSIRPLLVLFMVATVGSGGFGFDEVTASAIYGIFAGSL
YLAAVPGGWLADNWLGQERALWWGSIIIALGHLCIALSAMFGMTLFFMGLICIVLGSGLFKTCISVMVGALYPKGDSRRD
GGFTLFYMGINIGALLAALIVGVFKEKGMWHIGFGVGGLGMLASLIIYRFSAKKTLNRYASAKNITPEWEQSTGLFKNVG
QWVAGFLALLVAIVILVSTGIMPFNPEMVAEYMTYVIAAVVILYFAVMAISPRLDKTDKLRLLICFILIIGSTLFWSSFE
QQPTSFNLFADRYTDLNVLGFEVPSIWFQSLNPLFILILAPIASILWVKLGNRGLEPSSMTKFALGMLLAAAGFALMIFA
SKSILTADGGLASPLWLVGSLLLLTLGELALSPVGLSAMTKLAPKGMQGQMMGLFFASVALGNLVAAFFGGHVSADKIEG
LPGLFTTMTVFLVVTAVILLLLAKPINNMLKQSEHADQAS

Sequences:

>Translated_520_residues
MNIESKSEVSAAELASLENGFMGHPKPLRPLFFTEMWERFSYYSIRPLLVLFMVATVGSGGFGFDEVTASAIYGIFAGSL
YLAAVPGGWLADNWLGQERALWWGSIIIALGHLCIALSAMFGMTLFFMGLICIVLGSGLFKTCISVMVGALYPKGDSRRD
GGFTLFYMGINIGALLAALIVGVFKEKGMWHIGFGVGGLGMLASLIIYRFSAKKTLNRYASAKNITPEWEQSTGLFKNVG
QWVAGFLALLVAIVILVSTGIMPFNPEMVAEYMTYVIAAVVILYFAVMAISPRLDKTDKLRLLICFILIIGSTLFWSSFE
QQPTSFNLFADRYTDLNVLGFEVPSIWFQSLNPLFILILAPIASILWVKLGNRGLEPSSMTKFALGMLLAAAGFALMIFA
SKSILTADGGLASPLWLVGSLLLLTLGELALSPVGLSAMTKLAPKGMQGQMMGLFFASVALGNLVAAFFGGHVSADKIEG
LPGLFTTMTVFLVVTAVILLLLAKPINNMLKQSEHADQAS
>Mature_520_residues
MNIESKSEVSAAELASLENGFMGHPKPLRPLFFTEMWERFSYYSIRPLLVLFMVATVGSGGFGFDEVTASAIYGIFAGSL
YLAAVPGGWLADNWLGQERALWWGSIIIALGHLCIALSAMFGMTLFFMGLICIVLGSGLFKTCISVMVGALYPKGDSRRD
GGFTLFYMGINIGALLAALIVGVFKEKGMWHIGFGVGGLGMLASLIIYRFSAKKTLNRYASAKNITPEWEQSTGLFKNVG
QWVAGFLALLVAIVILVSTGIMPFNPEMVAEYMTYVIAAVVILYFAVMAISPRLDKTDKLRLLICFILIIGSTLFWSSFE
QQPTSFNLFADRYTDLNVLGFEVPSIWFQSLNPLFILILAPIASILWVKLGNRGLEPSSMTKFALGMLLAAAGFALMIFA
SKSILTADGGLASPLWLVGSLLLLTLGELALSPVGLSAMTKLAPKGMQGQMMGLFFASVALGNLVAAFFGGHVSADKIEG
LPGLFTTMTVFLVVTAVILLLLAKPINNMLKQSEHADQAS

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=407, Percent_Identity=24.3243243243243, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI226371746, Length=379, Percent_Identity=25.3298153034301, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI226371748, Length=373, Percent_Identity=24.9329758713137, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789911, Length=504, Percent_Identity=30.1587301587302, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1787922, Length=515, Percent_Identity=28.1553398058252, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1790572, Length=516, Percent_Identity=27.7131782945736, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1786927, Length=476, Percent_Identity=28.1512605042017, Blast_Score=175, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI71987453, Length=400, Percent_Identity=25.5, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17569141, Length=410, Percent_Identity=21.4634146341463, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24639581, Length=358, Percent_Identity=26.536312849162, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639585, Length=373, Percent_Identity=26.2734584450402, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639583, Length=373, Percent_Identity=26.2734584450402, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571098, Length=393, Percent_Identity=25.4452926208651, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571102, Length=393, Percent_Identity=25.4452926208651, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571100, Length=393, Percent_Identity=25.4452926208651, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56153; Mature: 56153

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIESKSEVSAAELASLENGFMGHPKPLRPLFFTEMWERFSYYSIRPLLVLFMVATVGSG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCC
GFGFDEVTASAIYGIFAGSLYLAAVPGGWLADNWLGQERALWWGSIIIALGHLCIALSAM
CCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FGMTLFFMGLICIVLGSGLFKTCISVMVGALYPKGDSRRDGGFTLFYMGINIGALLAALI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
VGVFKEKGMWHIGFGVGGLGMLASLIIYRFSAKKTLNRYASAKNITPEWEQSTGLFKNVG
HHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHH
QWVAGFLALLVAIVILVSTGIMPFNPEMVAEYMTYVIAAVVILYFAVMAISPRLDKTDKL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RLLICFILIIGSTLFWSSFEQQPTSFNLFADRYTDLNVLGFEVPSIWFQSLNPLFILILA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEECHHHHHHHHCCCHHHHHHHH
PIASILWVKLGNRGLEPSSMTKFALGMLLAAAGFALMIFASKSILTADGGLASPLWLVGS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHH
LLLLTLGELALSPVGLSAMTKLAPKGMQGQMMGLFFASVALGNLVAAFFGGHVSADKIEG
HHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCC
LPGLFTTMTVFLVVTAVILLLLAKPINNMLKQSEHADQAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNIESKSEVSAAELASLENGFMGHPKPLRPLFFTEMWERFSYYSIRPLLVLFMVATVGSG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCC
GFGFDEVTASAIYGIFAGSLYLAAVPGGWLADNWLGQERALWWGSIIIALGHLCIALSAM
CCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FGMTLFFMGLICIVLGSGLFKTCISVMVGALYPKGDSRRDGGFTLFYMGINIGALLAALI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
VGVFKEKGMWHIGFGVGGLGMLASLIIYRFSAKKTLNRYASAKNITPEWEQSTGLFKNVG
HHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHH
QWVAGFLALLVAIVILVSTGIMPFNPEMVAEYMTYVIAAVVILYFAVMAISPRLDKTDKL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RLLICFILIIGSTLFWSSFEQQPTSFNLFADRYTDLNVLGFEVPSIWFQSLNPLFILILA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEECHHHHHHHHCCCHHHHHHHH
PIASILWVKLGNRGLEPSSMTKFALGMLLAAAGFALMIFASKSILTADGGLASPLWLVGS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHH
LLLLTLGELALSPVGLSAMTKLAPKGMQGQMMGLFFASVALGNLVAAFFGGHVSADKIEG
HHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCC
LPGLFTTMTVFLVVTAVILLLLAKPINNMLKQSEHADQAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]