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The map label for this gene is aroC [H]

Identifier: 93006459

GI number: 93006459

Start: 2010980

End: 2012083

Strand: Reverse

Name: aroC [H]

Synonym: Pcryo_1635

Alternate gene names: 93006459

Gene position: 2012083-2010980 (Counterclockwise)

Preceding gene: 93006460

Following gene: 93006457

Centisome position: 65.76

GC content: 47.55

Gene sequence:

>1104_bases
ATGGCAGGCAACAGTATTGGGCAGGTCTTTACCGTCACCACCTGCGGTGAGTCGCATGGTGCAGGTTTGTTGGCAATCGT
CGATGGCGTGCCACCAGGTTTAGCCTTATCCGAAGCCGACTTGCAAATAGATTTGGATCGCCGTAAACCGGGTACTTCTA
AGTACTCGACCCAGCGCCGTGAATCTGATGAAGTCGAGATTATCTCTGGCGTTTTTGAAGGTAAAACGACAGGTACTTCT
ATCGGTCTACTGATTCGTAATACCAATCAAAAATCTAAAGACTATGGTGAAATTAAAGATACCTTTCGCCCTGGTCATGC
CGATTATACTTATAGTATGAAGTATGGCTTTCGTGACTATCGTGGCGGTGGTCGATCATCGGCGCGTGAGACTGCCATGC
GTGTAGCGGCAGGTGCTATCGCCAAAAAATACTTGCTAGAGCGCTTAGGTGTGCAAATCCGTGGTCATGTGACCCAAATT
GGTCATGAGTACAGTGATGTCCTAAACTCGAGCACAATCGATTGGGATTTTGTGAATAGTAATCCGTTTTTCTGTGCGGA
TGCCGATGCTGTCAGTCGCTTTGAGACCTTGATAGATAGTTTACGCCGTGAAGGTACGAGCTGTGGTGCCCGTCTTGAGA
TTATTGCAAGCGGTGTACCAGTTGGACTTGGTGAGCCTGTCTTTGACCGTTTAGATGCCGATATTGCCCATGCCATGATG
AGTATCAATGCTGTTAAAGGTGTTGAGATTGGTGATGGCATGGCAGTGGCAGGACAATTTGGGCATAGCTCTCGTGATGA
AATGACACCCGATGGTTTTACCGCCAATCATGCAGGCGGCATCTTGGGTGGTATCTCATCAGGACAAGATATCCGTGTCA
GTATTGCACTGAAGCCAACCTCTAGTATTACTACGGCTGGCAAGAGTATCAATACAGAGGGGGAGGCGATTGAGATGCTG
ACTAAAGGTCGTCATGATCCTTGCGTTGGTGTACGTGCAACACCTATCGCCGAAGCTATGTTAGCGATTGTGTTACTGGA
TCATTATCTGCGTCATCGTGGTCAAAATGCCGATATTAAGCAACCAGTCCAATCGATTACTTAA

Upstream 100 bases:

>100_bases
TTCGCCAATTATGTACAGTTACTAGATAGCAATCAATAAATCACGGTTGATACTATAATTCAAACAGTCAAAAATCGACT
TCATTTGTTTAAGGATAAAT

Downstream 100 bases:

>100_bases
GGTCCTTATGTCTTTATAACATGAGTAAGGTTGACCCTTTACATTATTTTAAACCTTTACAGTTGGCATAGTAACTGACC
GTTGCTGGCCAATCTGAGAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MAGNSIGQVFTVTTCGESHGAGLLAIVDGVPPGLALSEADLQIDLDRRKPGTSKYSTQRRESDEVEIISGVFEGKTTGTS
IGLLIRNTNQKSKDYGEIKDTFRPGHADYTYSMKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLLERLGVQIRGHVTQI
GHEYSDVLNSSTIDWDFVNSNPFFCADADAVSRFETLIDSLRREGTSCGARLEIIASGVPVGLGEPVFDRLDADIAHAMM
SINAVKGVEIGDGMAVAGQFGHSSRDEMTPDGFTANHAGGILGGISSGQDIRVSIALKPTSSITTAGKSINTEGEAIEML
TKGRHDPCVGVRATPIAEAMLAIVLLDHYLRHRGQNADIKQPVQSIT

Sequences:

>Translated_367_residues
MAGNSIGQVFTVTTCGESHGAGLLAIVDGVPPGLALSEADLQIDLDRRKPGTSKYSTQRRESDEVEIISGVFEGKTTGTS
IGLLIRNTNQKSKDYGEIKDTFRPGHADYTYSMKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLLERLGVQIRGHVTQI
GHEYSDVLNSSTIDWDFVNSNPFFCADADAVSRFETLIDSLRREGTSCGARLEIIASGVPVGLGEPVFDRLDADIAHAMM
SINAVKGVEIGDGMAVAGQFGHSSRDEMTPDGFTANHAGGILGGISSGQDIRVSIALKPTSSITTAGKSINTEGEAIEML
TKGRHDPCVGVRATPIAEAMLAIVLLDHYLRHRGQNADIKQPVQSIT
>Mature_366_residues
AGNSIGQVFTVTTCGESHGAGLLAIVDGVPPGLALSEADLQIDLDRRKPGTSKYSTQRRESDEVEIISGVFEGKTTGTSI
GLLIRNTNQKSKDYGEIKDTFRPGHADYTYSMKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLLERLGVQIRGHVTQIG
HEYSDVLNSSTIDWDFVNSNPFFCADADAVSRFETLIDSLRREGTSCGARLEIIASGVPVGLGEPVFDRLDADIAHAMMS
INAVKGVEIGDGMAVAGQFGHSSRDEMTPDGFTANHAGGILGGISSGQDIRVSIALKPTSSITTAGKSINTEGEAIEMLT
KGRHDPCVGVRATPIAEAMLAIVLLDHYLRHRGQNADIKQPVQSIT

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=69.4444444444444, Blast_Score=494, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6321290, Length=370, Percent_Identity=43.5135135135135, Blast_Score=279, Evalue=6e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39192; Mature: 39060

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQVFTVTTCGESHGAGLLAIVDGVPPGLALSEADLQIDLDRRKPGTSKYSTQRR
CCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEECCCEEEEECCCCCCCCCHHHHHC
ESDEVEIISGVFEGKTTGTSIGLLIRNTNQKSKDYGEIKDTFRPGHADYTYSMKYGFRDY
CCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEECCCHHH
RGGGRSSARETAMRVAAGAIAKKYLLERLGVQIRGHVTQIGHEYSDVLNSSTIDWDFVNS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCEEEEECC
NPFFCADADAVSRFETLIDSLRREGTSCGARLEIIASGVPVGLGEPVFDRLDADIAHAMM
CCCEEECHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
SINAVKGVEIGDGMAVAGQFGHSSRDEMTPDGFTANHAGGILGGISSGQDIRVSIALKPT
HHHHHCCEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCC
SSITTAGKSINTEGEAIEMLTKGRHDPCVGVRATPIAEAMLAIVLLDHYLRHRGQNADIK
CCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
QPVQSIT
HHHHHCC
>Mature Secondary Structure 
AGNSIGQVFTVTTCGESHGAGLLAIVDGVPPGLALSEADLQIDLDRRKPGTSKYSTQRR
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEECCCEEEEECCCCCCCCCHHHHHC
ESDEVEIISGVFEGKTTGTSIGLLIRNTNQKSKDYGEIKDTFRPGHADYTYSMKYGFRDY
CCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEECCCHHH
RGGGRSSARETAMRVAAGAIAKKYLLERLGVQIRGHVTQIGHEYSDVLNSSTIDWDFVNS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCEEEEECC
NPFFCADADAVSRFETLIDSLRREGTSCGARLEIIASGVPVGLGEPVFDRLDADIAHAMM
CCCEEECHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
SINAVKGVEIGDGMAVAGQFGHSSRDEMTPDGFTANHAGGILGGISSGQDIRVSIALKPT
HHHHHCCEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCC
SSITTAGKSINTEGEAIEMLTKGRHDPCVGVRATPIAEAMLAIVLLDHYLRHRGQNADIK
CCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
QPVQSIT
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA