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The map label for this gene is yfkJ [H]

Identifier: 93006295

GI number: 93006295

Start: 1810013

End: 1810507

Strand: Direct

Name: yfkJ [H]

Synonym: Pcryo_1469

Alternate gene names: 93006295

Gene position: 1810013-1810507 (Clockwise)

Preceding gene: 93006294

Following gene: 93006296

Centisome position: 59.15

GC content: 45.05

Gene sequence:

>495_bases
ATGCCCATCAAAGCGTCTACTCCGTCATCTGTATTATTGGTCTGTTTGGGGAATATCTGCCGTTCACCAACTGCTGAAGA
GATTTTTCGTCAGCAAGCAGCGATTGCAGGGCTGTCGATGAAGGTAGATTCGGCAGGCACTGGGGATTGGCATATTGGGC
ATGCACCTGATGAGCGCGCGCAGCGTCACGCTAAAGCTCATGGTTACAACATCAATAAATTGGTCGCGCGCCAAGTCAGT
GCTGATGACTTTCGCGATTTTGATTTAATATTGGCGATGGATGCACAAAATTTAGCAGACTTGCAGAGTATTAAAAACGG
TATAACAAATACCGATAAAAAATTAGCCAAATTGGCTTTATTTAGTGAGGAAGATCCCACTTACGGCGGTGATGATGTGC
CAGACCCATATACTGGTGATGGCGATGCTTTTGAAGAGGTAATCGAACGTATCGAATCAAGTGCACAAGCTTGGATTGAA
AGCTGGAAGATATAG

Upstream 100 bases:

>100_bases
GCTATCACCCATTAACTTACACTCTATAGCATGCTTATAAATCACATCTCTAATGTTGATTTTGATAGCATGTTTTTTTA
TTGCGACAAAAGGTCATCAT

Downstream 100 bases:

>100_bases
TAATCATAAGGCGCTATATTTTTGCTACCTTTATACCTAGCATCCTTTATAATAAATACCATATGACTTTTTGTTTACTT
GCCCCATAGGCTATGTTATG

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MPIKASTPSSVLLVCLGNICRSPTAEEIFRQQAAIAGLSMKVDSAGTGDWHIGHAPDERAQRHAKAHGYNINKLVARQVS
ADDFRDFDLILAMDAQNLADLQSIKNGITNTDKKLAKLALFSEEDPTYGGDDVPDPYTGDGDAFEEVIERIESSAQAWIE
SWKI

Sequences:

>Translated_164_residues
MPIKASTPSSVLLVCLGNICRSPTAEEIFRQQAAIAGLSMKVDSAGTGDWHIGHAPDERAQRHAKAHGYNINKLVARQVS
ADDFRDFDLILAMDAQNLADLQSIKNGITNTDKKLAKLALFSEEDPTYGGDDVPDPYTGDGDAFEEVIERIESSAQAWIE
SWKI
>Mature_163_residues
PIKASTPSSVLLVCLGNICRSPTAEEIFRQQAAIAGLSMKVDSAGTGDWHIGHAPDERAQRHAKAHGYNINKLVARQVSA
DDFRDFDLILAMDAQNLADLQSIKNGITNTDKKLAKLALFSEEDPTYGGDDVPDPYTGDGDAFEEVIERIESSAQAWIES
WKI

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=153, Percent_Identity=41.1764705882353, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI6005988, Length=153, Percent_Identity=38.562091503268, Blast_Score=103, Evalue=5e-23,
Organism=Homo sapiens, GI96304457, Length=78, Percent_Identity=48.7179487179487, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI87081812, Length=150, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=3e-17,
Organism=Escherichia coli, GI1788375, Length=153, Percent_Identity=32.0261437908497, Blast_Score=79, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325330, Length=156, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706770, Length=165, Percent_Identity=38.7878787878788, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI78706772, Length=165, Percent_Identity=38.7878787878788, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI78711846, Length=155, Percent_Identity=35.4838709677419, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706766, Length=153, Percent_Identity=32.6797385620915, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706768, Length=153, Percent_Identity=32.6797385620915, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706764, Length=96, Percent_Identity=40.625, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648069, Length=95, Percent_Identity=35.7894736842105, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17916; Mature: 17785

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKASTPSSVLLVCLGNICRSPTAEEIFRQQAAIAGLSMKVDSAGTGDWHIGHAPDERA
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHH
QRHAKAHGYNINKLVARQVSADDFRDFDLILAMDAQNLADLQSIKNGITNTDKKLAKLAL
HHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHH
FSEEDPTYGGDDVPDPYTGDGDAFEEVIERIESSAQAWIESWKI
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIKASTPSSVLLVCLGNICRSPTAEEIFRQQAAIAGLSMKVDSAGTGDWHIGHAPDERA
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHH
QRHAKAHGYNINKLVARQVSADDFRDFDLILAMDAQNLADLQSIKNGITNTDKKLAKLAL
HHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHH
FSEEDPTYGGDDVPDPYTGDGDAFEEVIERIESSAQAWIESWKI
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]