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The map label for this gene is dnaX [H]

Identifier: 93006233

GI number: 93006233

Start: 1727235

End: 1729292

Strand: Reverse

Name: dnaX [H]

Synonym: Pcryo_1407

Alternate gene names: 93006233

Gene position: 1729292-1727235 (Counterclockwise)

Preceding gene: 93006234

Following gene: 93006232

Centisome position: 56.52

GC content: 45.58

Gene sequence:

>2058_bases
ATGACGCAGCAATATCAAGTTTTAGCCCGCAAATACCGCCCCAAAAACTTTCACGAGTTGATTGGGCAAACGCATGTCTC
ACAGGCGTTGATCAATGCGATTGATTACAATCGTCTGCATCATGCTTATTTATTTACGGGTACGCGCGGTGTCGGTAAAA
CGACCATCGCCCGTATTTTGTCTAAATGTTTGAACTGTGATACTGGCATTACCAGTACCCCATGTGGCGTGTGTGATAAT
TGCGTGGCGATTGATCAAGGGCGTTTTATTGATCTGATTGAGATTGATGCGGCTTCTCGTACCAAAGTTGAGGACACGCG
CGAGCTACTGGATAATGTGCCGTATGCGCCAAGCCAAGGCCGTTATAAAGTCTACCTGATTGACGAAGTGCATATGCTGT
CGACACACAGTTTTAACGCGCTTCTTAAGACTTTGGAAGAGCCTCCTGAGCATGTCAAGTTCCTATTAGCCACTACGGAT
CCACAAAAGCTGCCGATTACTATTATCTCGCGCTGTCTGCAGTTCGTATTACGTCCTTTGTCGCAAAGCTTGCTCAGTGA
GCATTTAGCCAATGTTCTAACTCAAGAACAAGTAGGCTATACACAGCCTGCACTTTGGCAATTGGCTAGTGCGGCAAAAG
GCTCGGTACGTGATGCTTTATCCTTGACCGATCAAGCCATTGCTTTTGGCCAAGGTGCGCTTGATGATGTGACCGTTAAT
TCGATGCTCGGCTTGATTGATGCGGCCGACTTAGTGAGCTTAATTACAGATATCTATAATCATGATAAGCCTGCTGTCGC
TGCCCATATCGAGCAGATGCGTGCGCAAATGGTTGATGCTAGCAGTATGTTTGACGGACTCGCTGAGCTATTGCATCAGT
TGGCATTGTGTCAGCTGCTGCCCGAAGTCGCTCTCAATGTCAATGAAGCGCAAGCACAGCATATCGATCAGCTTGCCCAG
CATATGAGCCCTGACGTATTACAGCTTTATTATGAAATTGTGGTACAAGCACGGGAAGGCGTCAAGCTTGCCAGTACGCC
GATGCAAGCACTTGAGATGTGTATTTTACGTCTCTTAGCTTTTCGTCCCTTACCGGTTGATGAGATATTAGCCAATGTAC
TTGATAGTACGGTAATGGCTATAGAAAAACCTACTACCACTGTCTCTAGCGCTACATTAATCACTGAGCCAGTGTCATCA
TCATTAGAATTACAAACTCAATCTGATAATATCGTTTATGAGAATATTGATACAAGTGTCAATGATAAACAGGATGTTGG
TGCTGATAATAGTATTACTCAACATGAGCAATATTACTCAAATGACGAGGCTAGTCATTTAAACCAGTACGACAATTCTA
GCGTTTATGACACGCTAGAATTGTCCAATAATCAGCCTGAACCCGTTGTTGAACCCGTTGTTGAACCCGTTGTTGAACCC
GTTGTTGAACCCGTTGTTGAACCCGTTGTTGAACCCGTTGTTGAACCCGTTGTTGAACCCGTTGTTGAACCCGTTGTTGA
ACCCGTTGTTGAACCCGTTGTTGAACCCGTTGTTGAACCCGTTGTTGAACCCGTTGTTGAACCCGAGGTAAATGATTCTC
AATTATTAATTCAATCTGAAGACCCTCGGGCGCTTCTACGTTGTCCGCCGCAAGAATTGATAGGTGAGTGGACACCAGAA
AAATGGGACTATTGGCTACAAACTGCTCGTGAAGCCGCTAGTTTGGCTCAAGATGAATTGGCGCTTGCCCGTCAAGGTAT
GATGACAGGCAGCTGTAATGCCGAAGCCATCTTTGTCACAGCAGTCGATAGTAAGCATTTGCAGGCAACCTTTGAGCAGC
TAGCGACAAAGATGCAGGTACAATTCCCTGATGCTGCCATCAGCTTACGAATTGATAGCAGTATCGCGCAAGCCGATGAT
AAAACCCCAGAGCGTCGTCAACAAAAACGTCTCGTTGAGGCTAAAACAGTGGCAGAATCAAGATTGTTTAATACGCCAGT
GATGCAATATTTAACCGAGCGCGGCGAAGGAAAAATGGGCAAGGTTCAGTTATATTAA

Upstream 100 bases:

>100_bases
CGACACTTATTTTTGACATTTAGCTTCGATAACTGATTTTAAGATAAATTGCTAATTTGATGCTTTACTTATATTTTTAC
GACTTACCTTGGCATTCATT

Downstream 100 bases:

>100_bases
ACAGTCATACATTTATTAATTGATTGATAGTTTATAAAAATTAGCACTTTATTAAAAATATTGTATTTATTGAAAAATCA
AGGCGATATTTATCTATCAT

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 684

Protein sequence:

>685_residues
MTQQYQVLARKYRPKNFHELIGQTHVSQALINAIDYNRLHHAYLFTGTRGVGKTTIARILSKCLNCDTGITSTPCGVCDN
CVAIDQGRFIDLIEIDAASRTKVEDTRELLDNVPYAPSQGRYKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLLATTD
PQKLPITIISRCLQFVLRPLSQSLLSEHLANVLTQEQVGYTQPALWQLASAAKGSVRDALSLTDQAIAFGQGALDDVTVN
SMLGLIDAADLVSLITDIYNHDKPAVAAHIEQMRAQMVDASSMFDGLAELLHQLALCQLLPEVALNVNEAQAQHIDQLAQ
HMSPDVLQLYYEIVVQAREGVKLASTPMQALEMCILRLLAFRPLPVDEILANVLDSTVMAIEKPTTTVSSATLITEPVSS
SLELQTQSDNIVYENIDTSVNDKQDVGADNSITQHEQYYSNDEASHLNQYDNSSVYDTLELSNNQPEPVVEPVVEPVVEP
VVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPEVNDSQLLIQSEDPRALLRCPPQELIGEWTPE
KWDYWLQTAREAASLAQDELALARQGMMTGSCNAEAIFVTAVDSKHLQATFEQLATKMQVQFPDAAISLRIDSSIAQADD
KTPERRQQKRLVEAKTVAESRLFNTPVMQYLTERGEGKMGKVQLY

Sequences:

>Translated_685_residues
MTQQYQVLARKYRPKNFHELIGQTHVSQALINAIDYNRLHHAYLFTGTRGVGKTTIARILSKCLNCDTGITSTPCGVCDN
CVAIDQGRFIDLIEIDAASRTKVEDTRELLDNVPYAPSQGRYKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLLATTD
PQKLPITIISRCLQFVLRPLSQSLLSEHLANVLTQEQVGYTQPALWQLASAAKGSVRDALSLTDQAIAFGQGALDDVTVN
SMLGLIDAADLVSLITDIYNHDKPAVAAHIEQMRAQMVDASSMFDGLAELLHQLALCQLLPEVALNVNEAQAQHIDQLAQ
HMSPDVLQLYYEIVVQAREGVKLASTPMQALEMCILRLLAFRPLPVDEILANVLDSTVMAIEKPTTTVSSATLITEPVSS
SLELQTQSDNIVYENIDTSVNDKQDVGADNSITQHEQYYSNDEASHLNQYDNSSVYDTLELSNNQPEPVVEPVVEPVVEP
VVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPEVNDSQLLIQSEDPRALLRCPPQELIGEWTPE
KWDYWLQTAREAASLAQDELALARQGMMTGSCNAEAIFVTAVDSKHLQATFEQLATKMQVQFPDAAISLRIDSSIAQADD
KTPERRQQKRLVEAKTVAESRLFNTPVMQYLTERGEGKMGKVQLY
>Mature_684_residues
TQQYQVLARKYRPKNFHELIGQTHVSQALINAIDYNRLHHAYLFTGTRGVGKTTIARILSKCLNCDTGITSTPCGVCDNC
VAIDQGRFIDLIEIDAASRTKVEDTRELLDNVPYAPSQGRYKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLLATTDP
QKLPITIISRCLQFVLRPLSQSLLSEHLANVLTQEQVGYTQPALWQLASAAKGSVRDALSLTDQAIAFGQGALDDVTVNS
MLGLIDAADLVSLITDIYNHDKPAVAAHIEQMRAQMVDASSMFDGLAELLHQLALCQLLPEVALNVNEAQAQHIDQLAQH
MSPDVLQLYYEIVVQAREGVKLASTPMQALEMCILRLLAFRPLPVDEILANVLDSTVMAIEKPTTTVSSATLITEPVSSS
LELQTQSDNIVYENIDTSVNDKQDVGADNSITQHEQYYSNDEASHLNQYDNSSVYDTLELSNNQPEPVVEPVVEPVVEPV
VEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPEVNDSQLLIQSEDPRALLRCPPQELIGEWTPEK
WDYWLQTAREAASLAQDELALARQGMMTGSCNAEAIFVTAVDSKHLQATFEQLATKMQVQFPDAAISLRIDSSIAQADDK
TPERRQQKRLVEAKTVAESRLFNTPVMQYLTERGEGKMGKVQLY

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=336, Percent_Identity=24.1071428571429, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI194306571, Length=339, Percent_Identity=23.8938053097345, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI194306567, Length=339, Percent_Identity=23.8938053097345, Blast_Score=74, Evalue=6e-13,
Organism=Escherichia coli, GI1786676, Length=365, Percent_Identity=55.0684931506849, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1787119, Length=201, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787341, Length=315, Percent_Identity=26.3492063492064, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324039, Length=295, Percent_Identity=23.3898305084746, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 75864; Mature: 75733

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQYQVLARKYRPKNFHELIGQTHVSQALINAIDYNRLHHAYLFTGTRGVGKTTIARIL
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
SKCLNCDTGITSTPCGVCDNCVAIDQGRFIDLIEIDAASRTKVEDTRELLDNVPYAPSQG
HHHHCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCC
RYKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLLATTDPQKLPITIISRCLQFVLRPL
CEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHH
SQSLLSEHLANVLTQEQVGYTQPALWQLASAAKGSVRDALSLTDQAIAFGQGALDDVTVN
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SMLGLIDAADLVSLITDIYNHDKPAVAAHIEQMRAQMVDASSMFDGLAELLHQLALCQLL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PEVALNVNEAQAQHIDQLAQHMSPDVLQLYYEIVVQAREGVKLASTPMQALEMCILRLLA
HHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHH
FRPLPVDEILANVLDSTVMAIEKPTTTVSSATLITEPVSSSLELQTQSDNIVYENIDTSV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHEECCCCCCEEEEECCCCEEEECCCCCC
NDKQDVGADNSITQHEQYYSNDEASHLNQYDNSSVYDTLELSNNQPEPVVEPVVEPVVEP
CCCHHCCCCCCCHHHHHHHCCCCHHHHHHCCCCCCEEEHCCCCCCCCHHHHHHHHHHHHH
VVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPEVNDSQLLIQSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
DPRALLRCPPQELIGEWTPEKWDYWLQTAREAASLAQDELALARQGMMTGSCNAEAIFVT
CCHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
AVDSKHLQATFEQLATKMQVQFPDAAISLRIDSSIAQADDKTPERRQQKRLVEAKTVAES
ECCCHHHHHHHHHHHHHHHEECCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHH
RLFNTPVMQYLTERGEGKMGKVQLY
HHCCCHHHHHHHHCCCCCCCCEEEC
>Mature Secondary Structure 
TQQYQVLARKYRPKNFHELIGQTHVSQALINAIDYNRLHHAYLFTGTRGVGKTTIARIL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
SKCLNCDTGITSTPCGVCDNCVAIDQGRFIDLIEIDAASRTKVEDTRELLDNVPYAPSQG
HHHHCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCC
RYKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLLATTDPQKLPITIISRCLQFVLRPL
CEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHH
SQSLLSEHLANVLTQEQVGYTQPALWQLASAAKGSVRDALSLTDQAIAFGQGALDDVTVN
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SMLGLIDAADLVSLITDIYNHDKPAVAAHIEQMRAQMVDASSMFDGLAELLHQLALCQLL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PEVALNVNEAQAQHIDQLAQHMSPDVLQLYYEIVVQAREGVKLASTPMQALEMCILRLLA
HHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHH
FRPLPVDEILANVLDSTVMAIEKPTTTVSSATLITEPVSSSLELQTQSDNIVYENIDTSV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHEECCCCCCEEEEECCCCEEEECCCCCC
NDKQDVGADNSITQHEQYYSNDEASHLNQYDNSSVYDTLELSNNQPEPVVEPVVEPVVEP
CCCHHCCCCCCCHHHHHHHCCCCHHHHHHCCCCCCEEEHCCCCCCCCHHHHHHHHHHHHH
VVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPVVEPEVNDSQLLIQSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
DPRALLRCPPQELIGEWTPEKWDYWLQTAREAASLAQDELALARQGMMTGSCNAEAIFVT
CCHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
AVDSKHLQATFEQLATKMQVQFPDAAISLRIDSSIAQADDKTPERRQQKRLVEAKTVAES
ECCCHHHHHHHHHHHHHHHEECCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHH
RLFNTPVMQYLTERGEGKMGKVQLY
HHCCCHHHHHHHHCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]