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The map label for this gene is ttdR [H]

Identifier: 93006232

GI number: 93006232

Start: 1726096

End: 1726995

Strand: Reverse

Name: ttdR [H]

Synonym: Pcryo_1406

Alternate gene names: 93006232

Gene position: 1726995-1726096 (Counterclockwise)

Preceding gene: 93006233

Following gene: 93006229

Centisome position: 56.44

GC content: 41.33

Gene sequence:

>900_bases
ATGTTAGATAATTTACGTGGTATGGCTGTGTTTGCTAGTGTGGTCGGACACGGCTCCTTTAGTGGTTCAGCCCGTGAGCT
TGGTATCACCACCAGCGCCGTCAGTCAGCAAATACGTTCTTTAGAGAACGAGCTTGGTGTGGTGTTATTACATCGCTCAA
CCCGTAAGCTCAGCTTAACAGAAGCGGGTGCTAGCTTTTATGAAGCGGCAAAAGATGTGGTAAGTGCGGCAGAGCAAGGT
CGAATTAAAGTCAATCAATTACGTGATGAATTGGCAGGTAGTTTGCGTATTGCAACGACCCCAGAGCTTGGTGTCAATCA
TATTTTGCCAGCACTATCGACTTGGATGTCAGCGCACGATGATCTTAGTATTACCTATTTTGCAGATAATAATTATATTG
ATATGATTGATGAGCGAATCGATATTGCGATACGTATGAGCCCCAATATCAACGACTCAACTGTGAGCAATCATCCGTTA
TCTGATGTGCGTCAAATGTTGGTCGCTTCACCACAATATTTACGTCAACATAAGAAAATTGAAACACCGAAAGATTTGGC
GGATCATCATCTTATCTGTATTGATATCATGAAGGATACAAATAATGTTGAGCTGACTCAGACTGAGACTGGTAAAAAAA
CACGTATCAAAATGACGTCGCGTATCCATACCAATAACGTCTTTATGGCAATGACCATCGCTAAAGAAGGTCATGGTATT
CTTAGAATGATGGAAATGGATGTCAAAAAAGAGCTAGAATCGGGTAACTTGGTCGAAGTTCTAACCGGCTATCAGATGCC
AAGTTTTGTACTATATGCTGTAACCTTAAATCGTGAGCAACAGCCTGCAAAAATCACGCGTTGCTTAGAGGTATTAAAAA
AATACTTTCATGCAAACTAA

Upstream 100 bases:

>100_bases
ATCTTACTCTGAGTTTAATATTAAAAAACTGTAAGATTTATCATTATCCGCTATAATGGTTAAGTTATATTAACAACTAA
AAAGCAGCTTGGATGAGAAT

Downstream 100 bases:

>100_bases
GGTTTAGTTTATTTAAATGCTAACAAAGCTGAATGATTAATAATGAAAAAAGCCTATAGATAATTTATCTATAGGCTTTT
TATATTTTGGTTAAATAGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLDNLRGMAVFASVVGHGSFSGSARELGITTSAVSQQIRSLENELGVVLLHRSTRKLSLTEAGASFYEAAKDVVSAAEQG
RIKVNQLRDELAGSLRIATTPELGVNHILPALSTWMSAHDDLSITYFADNNYIDMIDERIDIAIRMSPNINDSTVSNHPL
SDVRQMLVASPQYLRQHKKIETPKDLADHHLICIDIMKDTNNVELTQTETGKKTRIKMTSRIHTNNVFMAMTIAKEGHGI
LRMMEMDVKKELESGNLVEVLTGYQMPSFVLYAVTLNREQQPAKITRCLEVLKKYFHAN

Sequences:

>Translated_299_residues
MLDNLRGMAVFASVVGHGSFSGSARELGITTSAVSQQIRSLENELGVVLLHRSTRKLSLTEAGASFYEAAKDVVSAAEQG
RIKVNQLRDELAGSLRIATTPELGVNHILPALSTWMSAHDDLSITYFADNNYIDMIDERIDIAIRMSPNINDSTVSNHPL
SDVRQMLVASPQYLRQHKKIETPKDLADHHLICIDIMKDTNNVELTQTETGKKTRIKMTSRIHTNNVFMAMTIAKEGHGI
LRMMEMDVKKELESGNLVEVLTGYQMPSFVLYAVTLNREQQPAKITRCLEVLKKYFHAN
>Mature_299_residues
MLDNLRGMAVFASVVGHGSFSGSARELGITTSAVSQQIRSLENELGVVLLHRSTRKLSLTEAGASFYEAAKDVVSAAEQG
RIKVNQLRDELAGSLRIATTPELGVNHILPALSTWMSAHDDLSITYFADNNYIDMIDERIDIAIRMSPNINDSTVSNHPL
SDVRQMLVASPQYLRQHKKIETPKDLADHHLICIDIMKDTNNVELTQTETGKKTRIKMTSRIHTNNVFMAMTIAKEGHGI
LRMMEMDVKKELESGNLVEVLTGYQMPSFVLYAVTLNREQQPAKITRCLEVLKKYFHAN

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=29.8969072164948, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=29.1525423728814, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87081978, Length=298, Percent_Identity=30.5369127516779, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786401, Length=261, Percent_Identity=27.9693486590038, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=26.0869565217391, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787589, Length=267, Percent_Identity=23.9700374531835, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1787128, Length=271, Percent_Identity=24.7232472324723, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789173, Length=257, Percent_Identity=29.1828793774319, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786448, Length=245, Percent_Identity=29.3877551020408, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI157672245, Length=146, Percent_Identity=31.5068493150685, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790011, Length=302, Percent_Identity=22.8476821192053, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786508, Length=91, Percent_Identity=36.2637362637363, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790399, Length=112, Percent_Identity=31.25, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788297, Length=145, Percent_Identity=27.5862068965517, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33411; Mature: 33411

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNLRGMAVFASVVGHGSFSGSARELGITTSAVSQQIRSLENELGVVLLHRSTRKLSLT
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEHH
EAGASFYEAAKDVVSAAEQGRIKVNQLRDELAGSLRIATTPELGVNHILPALSTWMSAHD
HHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCC
DLSITYFADNNYIDMIDERIDIAIRMSPNINDSTVSNHPLSDVRQMLVASPQYLRQHKKI
CCEEEEEECCCCCEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCC
ETPKDLADHHLICIDIMKDTNNVELTQTETGKKTRIKMTSRIHTNNVFMAMTIAKEGHGI
CCCHHHHCCEEEEEEEEECCCCEEEEECCCCCEEEEEEEEEEECCCEEEEEEEECCCCCH
LRMMEMDVKKELESGNLVEVLTGYQMPSFVLYAVTLNREQQPAKITRCLEVLKKYFHAN
HHHHHHHHHHHHCCCCEEEEHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDNLRGMAVFASVVGHGSFSGSARELGITTSAVSQQIRSLENELGVVLLHRSTRKLSLT
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEHH
EAGASFYEAAKDVVSAAEQGRIKVNQLRDELAGSLRIATTPELGVNHILPALSTWMSAHD
HHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCC
DLSITYFADNNYIDMIDERIDIAIRMSPNINDSTVSNHPLSDVRQMLVASPQYLRQHKKI
CCEEEEEECCCCCEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCC
ETPKDLADHHLICIDIMKDTNNVELTQTETGKKTRIKMTSRIHTNNVFMAMTIAKEGHGI
CCCHHHHCCEEEEEEEEECCCCEEEEECCCCCEEEEEEEEEEECCCEEEEEEEECCCCCH
LRMMEMDVKKELESGNLVEVLTGYQMPSFVLYAVTLNREQQPAKITRCLEVLKKYFHAN
HHHHHHHHHHHHCCCCEEEEHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]