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The map label for this gene is hsdM [C]

Identifier: 93006185

GI number: 93006185

Start: 1661546

End: 1663135

Strand: Direct

Name: hsdM [C]

Synonym: Pcryo_1359

Alternate gene names: 93006185

Gene position: 1661546-1663135 (Clockwise)

Preceding gene: 93006184

Following gene: 93006186

Centisome position: 54.3

GC content: 47.3

Gene sequence:

>1590_bases
ATGGCTAAAACACCTGCGAACAAAAAAGATAAAACAGACAATGGCAATTTTGAAGAAGCCCTTTGGGATGCTGCCAACAA
GCTACGAGGTAGCGTCGAATCATCAGAATATAAGCACATCGTCCTTAGCCTAATTTTCTTAAAATTCATCAGTGATACTT
TCGAGCAGCAGCGCCAAAAACTGATCGATACAGGCTATGAAAAGCATATCAACATGGTGCAAGCTTATACCAAAGATAAC
GTGTTCTACTTGCCAGAGGAGAGCCGTTGGAGTTTTATCCAGCAGAATGCTAAGCAAGAAGACATCGCGCTTAAAATCGA
CACGGCGCTCAGTACCATCGAAAAGACCAACCAATCATTGAAAGGCGCATTGCCTGACAACTACTTCTCACGTCTAGGCT
TAACGGCCAGTAAGCTTGCCGCCTTGATTGATGTGGTCAATAACATCGACACTATCGGTAATCCAGAAGAAGACACGGTA
GGGCGCGTGTACGAGTATTTCTTGGGTAAGTTTGCTGCAACTGAAGGTAAAGGCGGTGGTGAGTTCTATACGCCTAAGTC
TGTGGTCAATCTGATTGCAGAAATGGTTGAGCCATATCAAGGCAAAATCTACGATCCGTGCTGCGGCTCGGGCGGTATGT
TCGTCCAGTCCATCAAATTCATCGAGAGTCACCACGGCAATACCAAAGATGTGTCTATCTATGGGCAAGAGTACACCAGC
ACGACCTACAAGCTCGCTAAGATGAACCTTGCCATTCGTGGTATCTCTAGCAACTTGGGTGATGTGGCTGCCGATACTTT
CTTTAAAGATCAGCACGAAGACCTAAAAGCCGATTTCATCATGGCAAACCCACCTTTTAACCAAAAGGATTGGCGCGCCT
CTGATGAGCTGGTCGATGACCCACGCTGGGCAGGGTATCCGACACCGCCTACGGGCAATGCCAACTATGCATGGATATTG
CACATGATATCCAAGCTCTCTGAGCATGGAACTGCTGGTTTTGTACTTGCCAATGGTTCGATGTCTACCACCACCAGTGG
TGAGGGTGAGATACGCGAGCAAATCATCAAAAACGATCTGGTCGATTGTATGATTGCGCTACCGGGTCAGCTGTTTTATA
CCACGCAGATTCCGGTGTGTTTATGGTTTATCAGTAAAGACAAACAAGCTACGTCAGCTGATAGTAAGGCAAAGGGGTTG
CGTAACCGTAGCGGTGAGACGCTGTTCATTGATGCCCGTAATATCGGTGCGATGATTGACCGTACGCATAAAGAGTTTTC
TACTGATGATATCGAAGCGATTGCCAAGACTTATCATGCATGGCGCGGTGAGAAAGAAGCGGGCGGCTATGAAGCCTACG
CAGATGAAGCAGGCTATTGTAAATCCGCCAGTCTAGACGATATCAAAGCCAATGACTATGTGCTGACGCCTGGGCGTTAT
GTTGGGGCGGCAGCTATCGAAGATGATGGCATTCCGTTTGAGACTAAGATGCTGGAGCTAAGCCAAACGCTATATGCACA
GATGCAAGAGTCCGAAAAGCTAGATGCGACCATTCGTCAGAACTTGGAGGTATTGGGTTATGGCGAGTGA

Upstream 100 bases:

>100_bases
ACATCGTAAAGGTAGTCGGAATCATATCTGTATTGCATATGAAAATTAAACACAATTCATCATACAAATTAAAAGTATCA
CAAATAGAGATTAAAGAAAC

Downstream 100 bases:

>100_bases
TTGGGTAAAAACAACTCTTGGAGAAATAGTAAAGCTGGGCAATGGAATAATTCAGACAGGACCATTTGGTAGCCAATTGC
ATGCCTCTGATTATGTTGAT

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MAKTPANKKDKTDNGNFEEALWDAANKLRGSVESSEYKHIVLSLIFLKFISDTFEQQRQKLIDTGYEKHINMVQAYTKDN
VFYLPEESRWSFIQQNAKQEDIALKIDTALSTIEKTNQSLKGALPDNYFSRLGLTASKLAALIDVVNNIDTIGNPEEDTV
GRVYEYFLGKFAATEGKGGGEFYTPKSVVNLIAEMVEPYQGKIYDPCCGSGGMFVQSIKFIESHHGNTKDVSIYGQEYTS
TTYKLAKMNLAIRGISSNLGDVAADTFFKDQHEDLKADFIMANPPFNQKDWRASDELVDDPRWAGYPTPPTGNANYAWIL
HMISKLSEHGTAGFVLANGSMSTTTSGEGEIREQIIKNDLVDCMIALPGQLFYTTQIPVCLWFISKDKQATSADSKAKGL
RNRSGETLFIDARNIGAMIDRTHKEFSTDDIEAIAKTYHAWRGEKEAGGYEAYADEAGYCKSASLDDIKANDYVLTPGRY
VGAAAIEDDGIPFETKMLELSQTLYAQMQESEKLDATIRQNLEVLGYGE

Sequences:

>Translated_529_residues
MAKTPANKKDKTDNGNFEEALWDAANKLRGSVESSEYKHIVLSLIFLKFISDTFEQQRQKLIDTGYEKHINMVQAYTKDN
VFYLPEESRWSFIQQNAKQEDIALKIDTALSTIEKTNQSLKGALPDNYFSRLGLTASKLAALIDVVNNIDTIGNPEEDTV
GRVYEYFLGKFAATEGKGGGEFYTPKSVVNLIAEMVEPYQGKIYDPCCGSGGMFVQSIKFIESHHGNTKDVSIYGQEYTS
TTYKLAKMNLAIRGISSNLGDVAADTFFKDQHEDLKADFIMANPPFNQKDWRASDELVDDPRWAGYPTPPTGNANYAWIL
HMISKLSEHGTAGFVLANGSMSTTTSGEGEIREQIIKNDLVDCMIALPGQLFYTTQIPVCLWFISKDKQATSADSKAKGL
RNRSGETLFIDARNIGAMIDRTHKEFSTDDIEAIAKTYHAWRGEKEAGGYEAYADEAGYCKSASLDDIKANDYVLTPGRY
VGAAAIEDDGIPFETKMLELSQTLYAQMQESEKLDATIRQNLEVLGYGE
>Mature_528_residues
AKTPANKKDKTDNGNFEEALWDAANKLRGSVESSEYKHIVLSLIFLKFISDTFEQQRQKLIDTGYEKHINMVQAYTKDNV
FYLPEESRWSFIQQNAKQEDIALKIDTALSTIEKTNQSLKGALPDNYFSRLGLTASKLAALIDVVNNIDTIGNPEEDTVG
RVYEYFLGKFAATEGKGGGEFYTPKSVVNLIAEMVEPYQGKIYDPCCGSGGMFVQSIKFIESHHGNTKDVSIYGQEYTST
TYKLAKMNLAIRGISSNLGDVAADTFFKDQHEDLKADFIMANPPFNQKDWRASDELVDDPRWAGYPTPPTGNANYAWILH
MISKLSEHGTAGFVLANGSMSTTTSGEGEIREQIIKNDLVDCMIALPGQLFYTTQIPVCLWFISKDKQATSADSKAKGLR
NRSGETLFIDARNIGAMIDRTHKEFSTDDIEAIAKTYHAWRGEKEAGGYEAYADEAGYCKSASLDDIKANDYVLTPGRYV
GAAAIEDDGIPFETKMLELSQTLYAQMQESEKLDATIRQNLEVLGYGE

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=397, Percent_Identity=22.9219143576826, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 58891; Mature: 58759

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTPANKKDKTDNGNFEEALWDAANKLRGSVESSEYKHIVLSLIFLKFISDTFEQQRQK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDTGYEKHINMVQAYTKDNVFYLPEESRWSFIQQNAKQEDIALKIDTALSTIEKTNQSL
HHHCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
KGALPDNYFSRLGLTASKLAALIDVVNNIDTIGNPEEDTVGRVYEYFLGKFAATEGKGGG
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
EFYTPKSVVNLIAEMVEPYQGKIYDPCCGSGGMFVQSIKFIESHHGNTKDVSIYGQEYTS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHCC
TTYKLAKMNLAIRGISSNLGDVAADTFFKDQHEDLKADFIMANPPFNQKDWRASDELVDD
HHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHCCC
PRWAGYPTPPTGNANYAWILHMISKLSEHGTAGFVLANGSMSTTTSGEGEIREQIIKNDL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
VDCMIALPGQLFYTTQIPVCLWFISKDKQATSADSKAKGLRNRSGETLFIDARNIGAMID
HHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHH
RTHKEFSTDDIEAIAKTYHAWRGEKEAGGYEAYADEAGYCKSASLDDIKANDYVLTPGRY
HHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEECCCCE
VGAAAIEDDGIPFETKMLELSQTLYAQMQESEKLDATIRQNLEVLGYGE
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
AKTPANKKDKTDNGNFEEALWDAANKLRGSVESSEYKHIVLSLIFLKFISDTFEQQRQK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDTGYEKHINMVQAYTKDNVFYLPEESRWSFIQQNAKQEDIALKIDTALSTIEKTNQSL
HHHCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
KGALPDNYFSRLGLTASKLAALIDVVNNIDTIGNPEEDTVGRVYEYFLGKFAATEGKGGG
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
EFYTPKSVVNLIAEMVEPYQGKIYDPCCGSGGMFVQSIKFIESHHGNTKDVSIYGQEYTS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHCC
TTYKLAKMNLAIRGISSNLGDVAADTFFKDQHEDLKADFIMANPPFNQKDWRASDELVDD
HHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHCCC
PRWAGYPTPPTGNANYAWILHMISKLSEHGTAGFVLANGSMSTTTSGEGEIREQIIKNDL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
VDCMIALPGQLFYTTQIPVCLWFISKDKQATSADSKAKGLRNRSGETLFIDARNIGAMID
HHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHH
RTHKEFSTDDIEAIAKTYHAWRGEKEAGGYEAYADEAGYCKSASLDDIKANDYVLTPGRY
HHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEECCCCE
VGAAAIEDDGIPFETKMLELSQTLYAQMQESEKLDATIRQNLEVLGYGE
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]