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The map label for this gene is tolQ [H]

Identifier: 93005964

GI number: 93005964

Start: 1371041

End: 1371781

Strand: Reverse

Name: tolQ [H]

Synonym: Pcryo_1136

Alternate gene names: 93005964

Gene position: 1371781-1371041 (Counterclockwise)

Preceding gene: 93005972

Following gene: 93005963

Centisome position: 44.83

GC content: 46.56

Gene sequence:

>741_bases
ATGCCTGAATCCTTAAATATTATCGACCTTATTACTCAAGCGAGCCTGCTGGTTCAGATCGTGATGGCTCTATTGTTATT
AGCATCGTTACTCAGTTGGGTGATTATTTTTCGTATGAGTGCGCGGCTTGGCACTGCCAGAAACTTTGACCAACAGTTCG
AGGCTTGGTTTTGGTCGGGTGAAGATTTGGCGAAATTGTATCAAGGTATTCAGGGCTCACCTGAGCGCCAAGGTCTTGAG
CAGATTTTCTATGTTGGCTTCTCTGAATACTTAAGAATGCACAAAAAACGTCAACCAAAAGATGACATTATCGATGGCGT
TGAGCGTAAGCTTAGGGTTGGTCTTGGTCGTCAGCAGCTACTTTTGGAGTCAGGACTTACAACGCTTGCCAGTATCGGCT
CCGTTGCACCTTACGTCGGTTTGTTCGGCACCGTTTGGGGTATCATGAATGCCTTTTTGGGGTTGTCACAAAATGAACAA
GCTACCCTAGCCGCTGTGGCACCAGGTATTGCAGAAGCATTAATTGCCACCGCTATGGGTTTGTTTGCCGCTATTCCTGC
AGTATTGGCTTATAACCATTTTACCGCTAAATCTAGTCGATTATATGATTCACGTGCCTTATTCTGTGATGAGATGACGG
GTATGCTGCAGCGCGAAACCAGTAATGAAAGCCCGCAGCCTAGCACTCAAGTAAGCCAAGCCAACCAAGCCAACCAAAGC
ACTCAGGTGGCTGGTCTATGA

Upstream 100 bases:

>100_bases
ACATTATTAATGATATTTACCAAGATTAGCAGTACACTAGGGGGTTAATATGAGCACCCTATTTTTAATGACTATTATTA
ATTATCCATGAGTCCTTTAC

Downstream 100 bases:

>100_bases
AACAAAGTCCCTATCGCCGTGAGAAAAAAGCACTGAATGCGGAGATGAACGTTGTTCCTTATATCGACGTAATGCTCGTT
CTGCTCGTGATATTTATGGT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPESLNIIDLITQASLLVQIVMALLLLASLLSWVIIFRMSARLGTARNFDQQFEAWFWSGEDLAKLYQGIQGSPERQGLE
QIFYVGFSEYLRMHKKRQPKDDIIDGVERKLRVGLGRQQLLLESGLTTLASIGSVAPYVGLFGTVWGIMNAFLGLSQNEQ
ATLAAVAPGIAEALIATAMGLFAAIPAVLAYNHFTAKSSRLYDSRALFCDEMTGMLQRETSNESPQPSTQVSQANQANQS
TQVAGL

Sequences:

>Translated_246_residues
MPESLNIIDLITQASLLVQIVMALLLLASLLSWVIIFRMSARLGTARNFDQQFEAWFWSGEDLAKLYQGIQGSPERQGLE
QIFYVGFSEYLRMHKKRQPKDDIIDGVERKLRVGLGRQQLLLESGLTTLASIGSVAPYVGLFGTVWGIMNAFLGLSQNEQ
ATLAAVAPGIAEALIATAMGLFAAIPAVLAYNHFTAKSSRLYDSRALFCDEMTGMLQRETSNESPQPSTQVSQANQANQS
TQVAGL
>Mature_245_residues
PESLNIIDLITQASLLVQIVMALLLLASLLSWVIIFRMSARLGTARNFDQQFEAWFWSGEDLAKLYQGIQGSPERQGLEQ
IFYVGFSEYLRMHKKRQPKDDIIDGVERKLRVGLGRQQLLLESGLTTLASIGSVAPYVGLFGTVWGIMNAFLGLSQNEQA
TLAAVAPGIAEALIATAMGLFAAIPAVLAYNHFTAKSSRLYDSRALFCDEMTGMLQRETSNESPQPSTQVSQANQANQST
QVAGL

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=226, Percent_Identity=45.575221238938, Blast_Score=190, Evalue=6e-50,
Organism=Escherichia coli, GI1789381, Length=213, Percent_Identity=36.150234741784, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26961; Mature: 26830

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
PESLNIIDLITQASLLVQIVMALLLLASLLSWVIIFRMSARLGTARNFDQQFEAWFWSG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
EDLAKLYQGIQGSPERQGLEQIFYVGFSEYLRMHKKRQPKDDIIDGVERKLRVGLGRQQL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHH
LLESGLTTLASIGSVAPYVGLFGTVWGIMNAFLGLSQNEQATLAAVAPGIAEALIATAMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LFAAIPAVLAYNHFTAKSSRLYDSRALFCDEMTGMLQRETSNESPQPSTQVSQANQANQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TQVAGL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]