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The map label for this gene is uvrA [H]

Identifier: 93005694

GI number: 93005694

Start: 1024001

End: 1026562

Strand: Reverse

Name: uvrA [H]

Synonym: Pcryo_0866

Alternate gene names: 93005694

Gene position: 1026562-1024001 (Counterclockwise)

Preceding gene: 93005696

Following gene: 93005688

Centisome position: 33.55

GC content: 49.1

Gene sequence:

>2562_bases
ATGACCACTAAAAATAAAAAAGTAAAACCCACTGCAAAAGTCGATGACAATGCCACTAAAGATATCGCTTGCGACCCTGC
TCATAGTATCCAAGTCAGAGGCGCAAGGGTTCATAATCTAAAAAACGTCGATGTTGATTTGCCGCGTAATGCCCTTGTGG
TATTCACGGGTATATCAGGGTCAGGCAAATCTTCACTGGCATTCGGTACTCTTTTTGCTGAGTCACAACATCGCTATCTT
GACTCAGTATCGCCTTATGCCAGACGCTTGATCGATCAAGTGGATCAGCCTGATGTCGATTCGATAGAAGGCTTGCCGCC
CGCCGTTGCCCTGCAACAACAACGAGGCACGCCGTCTGTGCGCTCATCGGTTGGTAGTGTCACGACGATTTCGAATGGCT
TACGCATGCTCTACTCGCGAGCGGGCGAATACCCTGCTGGTCAAGACATACTCTACGCTGACGCGTTCTCTCCAAATACG
CCAGATGGCGCTTGCCCTACTTGCTCCGGTATTGGCCGCGTGTTTGAGGTAACAGAAGAATTGCTAGTTCCTGACAATAC
CAAAACCATTCGCGAACGCGCCATTGCCGCTTGGCCGCCTGCATGGCAAGGGCAAAACCTAAGCCGTATCCTGACCTCAC
TTGGCTACGATATCGATAAGCCGTGGAATACCCTGCCCCAAAAAACCCGCGATTGGATTCTCTTTACCGACGACACCCCA
GAAGTCCCTGTCTATCCAGAATACAACATTGAACAAGTACGTGACGCTATTAAAAAAGGTGAAAAACCCAATTATAAAGG
GACGTTTACCAGTGCTAAGAATTTCGTCTTGCATTCTTTTGCCAGTACGCAAAGCCCGCGTACCAAAAAGCGCGTTTCCC
AGTTTATGCAAATTTCTGAATGTCCAGAATGCCATGGCAAAAAACTCAAAAAAGAATCGCTATCGGTGAAATTCGCGGGT
CTTGATATTGGTGAATTATCGCAATTAACCTTGACTGAAATGGCGCTTAAACTTCAGGATGCTGCCAAGACCAAACCAAA
TGACAACATGCCAAACCGAGAAAAGGCCATTGTTGCTCAACGTATTGCCAGTGACATTCTGTCTCGAGTTGAGGCGTTGA
CCACACTAGGCTTAGGGTATCTTTCGCTTGAACGCACTACACCTACTTTGTCTCCGGGTGAATTACAACGCCTAAGACTC
GCTACCCAAATTCGCTCTAAACTGTTTGGTGTGGTCTATGTGCTTGATGAGCCGTCTGCTGGATTACATCCTGCCGATAC
TCAAGCGCTATTGGGCGCATTGGATGAGCTGACAGCGGCTGGTAACTCGTTATTTATTGTTGAGCATGATGTCAGCGTGA
TTCGGCACGCCGATTGGATTGTCGATGTGGGGCCAAAGGCTGGAACCCATGGCGGCGAAGTTATTTACAGTGGCCCTGTA
GCAGGCTTGCGGGACGTTGCGCAATCACGCACGGGACAGTATCTTTTTGAGACTGAAGGGGCGGTTGAGCATACCCCAAG
AAAAGCAAAAGCCTCGCTACAGCTGGTCAATATCGAACGCAACAACTTACAAGGGCTAGATGTAGCGTTTCCTCTAGGGG
TGATGACAACGGTGACGGGCGTATCAGGTTCAGGCAAATCAAGTCTAGTCAGTCAAGCGCTGGTCGATCTCATTTATAGC
GAATTAGGGCAGAAGACAATCATCGAAGCACCGACTGGCGAAGCTGATTTACTAGAGCAAGAGCTAGAAACTCAGACCAG
CGGTAAGATTGCTAATGGTATGGAGCACGTAAGTCGATTGGTGACCGTCGATCAAAAAGCCATCGGTCGTACGCCGCGCT
CAAACCTTGCTACTTATACCGGCCTGTTCGATCATGTGCGCAAATTATTTGCCGCAACGCCAGAAGCCAAGGCACGACGT
TACGATGCCGGTCGCTTCTCCTTTAACGTTAAGAAAGGCCGCTGCCCAAATTGTGAAGGTGTTGGTTTTGTGAGTGTTGA
GCTGCTATTTCTGCCGAGCGTTTACTCGCCGTGCCAAGTGTGTCATGGGCAACGCTACAATGATGAAACCCTTGAGATCA
CTTATCGAGGCAAAAATATCGCTGAAATCCTCGATCTCACTGTCGAATCTGCTTATGAATTCTTTGTAGAAGAATCATCT
ATCCTACGAGCATTAGACGCGTTGCTAAAAGTCGGACTGGGTTATCTCAGGCTTGGTCAGCCAGCAACCGAGCTTTCGGG
CGGTGAAGCACAGCGCATTAAGCTTGCCACCGAACTGCAACGGACACAACGAGGAGACACGCTTTATATCCTTGATGAAC
CAACAACTGGCCTGCACCCTTCGGATGTGTCGCTATTGATGGCGCAATTGAACGGACTCGTTGACGCTGGTAACACTGTG
ATTATGGTTGAGCATGACATGCAAGTCGCTAGTAACAGTGATTGGATTATCGATATTGGGCCGGGCGCTGGCGATGAGGG
CGGTCTTATTGTGGCAGAAGGCACACCAGCAGAGGTTGCGAAGTCAAAAGCCAGTCGTACCGCGCCTTTTTTGCTGTTTT
AG

Upstream 100 bases:

>100_bases
TTAATTAGCTAACTATTTAGCAAGCAGTTTCTTGGCCAAAACTTTACCCGTCTTTTTCAAAATAAAGCTAAAAATACGAT
TTGATAGGAATAACTGTTTT

Downstream 100 bases:

>100_bases
TCTATTAGGGCACATTTTATTAAAAATCTTTTATCAACTCAGCAACTGACGGCAGCGCTCAATTACGGGCGCGTCGACCA
TTTGACCTGCTATTTTAAAT

Product: excinuclease ABC subunit A

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 853; Mature: 852

Protein sequence:

>853_residues
MTTKNKKVKPTAKVDDNATKDIACDPAHSIQVRGARVHNLKNVDVDLPRNALVVFTGISGSGKSSLAFGTLFAESQHRYL
DSVSPYARRLIDQVDQPDVDSIEGLPPAVALQQQRGTPSVRSSVGSVTTISNGLRMLYSRAGEYPAGQDILYADAFSPNT
PDGACPTCSGIGRVFEVTEELLVPDNTKTIRERAIAAWPPAWQGQNLSRILTSLGYDIDKPWNTLPQKTRDWILFTDDTP
EVPVYPEYNIEQVRDAIKKGEKPNYKGTFTSAKNFVLHSFASTQSPRTKKRVSQFMQISECPECHGKKLKKESLSVKFAG
LDIGELSQLTLTEMALKLQDAAKTKPNDNMPNREKAIVAQRIASDILSRVEALTTLGLGYLSLERTTPTLSPGELQRLRL
ATQIRSKLFGVVYVLDEPSAGLHPADTQALLGALDELTAAGNSLFIVEHDVSVIRHADWIVDVGPKAGTHGGEVIYSGPV
AGLRDVAQSRTGQYLFETEGAVEHTPRKAKASLQLVNIERNNLQGLDVAFPLGVMTTVTGVSGSGKSSLVSQALVDLIYS
ELGQKTIIEAPTGEADLLEQELETQTSGKIANGMEHVSRLVTVDQKAIGRTPRSNLATYTGLFDHVRKLFAATPEAKARR
YDAGRFSFNVKKGRCPNCEGVGFVSVELLFLPSVYSPCQVCHGQRYNDETLEITYRGKNIAEILDLTVESAYEFFVEESS
ILRALDALLKVGLGYLRLGQPATELSGGEAQRIKLATELQRTQRGDTLYILDEPTTGLHPSDVSLLMAQLNGLVDAGNTV
IMVEHDMQVASNSDWIIDIGPGAGDEGGLIVAEGTPAEVAKSKASRTAPFLLF

Sequences:

>Translated_853_residues
MTTKNKKVKPTAKVDDNATKDIACDPAHSIQVRGARVHNLKNVDVDLPRNALVVFTGISGSGKSSLAFGTLFAESQHRYL
DSVSPYARRLIDQVDQPDVDSIEGLPPAVALQQQRGTPSVRSSVGSVTTISNGLRMLYSRAGEYPAGQDILYADAFSPNT
PDGACPTCSGIGRVFEVTEELLVPDNTKTIRERAIAAWPPAWQGQNLSRILTSLGYDIDKPWNTLPQKTRDWILFTDDTP
EVPVYPEYNIEQVRDAIKKGEKPNYKGTFTSAKNFVLHSFASTQSPRTKKRVSQFMQISECPECHGKKLKKESLSVKFAG
LDIGELSQLTLTEMALKLQDAAKTKPNDNMPNREKAIVAQRIASDILSRVEALTTLGLGYLSLERTTPTLSPGELQRLRL
ATQIRSKLFGVVYVLDEPSAGLHPADTQALLGALDELTAAGNSLFIVEHDVSVIRHADWIVDVGPKAGTHGGEVIYSGPV
AGLRDVAQSRTGQYLFETEGAVEHTPRKAKASLQLVNIERNNLQGLDVAFPLGVMTTVTGVSGSGKSSLVSQALVDLIYS
ELGQKTIIEAPTGEADLLEQELETQTSGKIANGMEHVSRLVTVDQKAIGRTPRSNLATYTGLFDHVRKLFAATPEAKARR
YDAGRFSFNVKKGRCPNCEGVGFVSVELLFLPSVYSPCQVCHGQRYNDETLEITYRGKNIAEILDLTVESAYEFFVEESS
ILRALDALLKVGLGYLRLGQPATELSGGEAQRIKLATELQRTQRGDTLYILDEPTTGLHPSDVSLLMAQLNGLVDAGNTV
IMVEHDMQVASNSDWIIDIGPGAGDEGGLIVAEGTPAEVAKSKASRTAPFLLF
>Mature_852_residues
TTKNKKVKPTAKVDDNATKDIACDPAHSIQVRGARVHNLKNVDVDLPRNALVVFTGISGSGKSSLAFGTLFAESQHRYLD
SVSPYARRLIDQVDQPDVDSIEGLPPAVALQQQRGTPSVRSSVGSVTTISNGLRMLYSRAGEYPAGQDILYADAFSPNTP
DGACPTCSGIGRVFEVTEELLVPDNTKTIRERAIAAWPPAWQGQNLSRILTSLGYDIDKPWNTLPQKTRDWILFTDDTPE
VPVYPEYNIEQVRDAIKKGEKPNYKGTFTSAKNFVLHSFASTQSPRTKKRVSQFMQISECPECHGKKLKKESLSVKFAGL
DIGELSQLTLTEMALKLQDAAKTKPNDNMPNREKAIVAQRIASDILSRVEALTTLGLGYLSLERTTPTLSPGELQRLRLA
TQIRSKLFGVVYVLDEPSAGLHPADTQALLGALDELTAAGNSLFIVEHDVSVIRHADWIVDVGPKAGTHGGEVIYSGPVA
GLRDVAQSRTGQYLFETEGAVEHTPRKAKASLQLVNIERNNLQGLDVAFPLGVMTTVTGVSGSGKSSLVSQALVDLIYSE
LGQKTIIEAPTGEADLLEQELETQTSGKIANGMEHVSRLVTVDQKAIGRTPRSNLATYTGLFDHVRKLFAATPEAKARRY
DAGRFSFNVKKGRCPNCEGVGFVSVELLFLPSVYSPCQVCHGQRYNDETLEITYRGKNIAEILDLTVESAYEFFVEESSI
LRALDALLKVGLGYLRLGQPATELSGGEAQRIKLATELQRTQRGDTLYILDEPTTGLHPSDVSLLMAQLNGLVDAGNTVI
MVEHDMQVASNSDWIIDIGPGAGDEGGLIVAEGTPAEVAKSKASRTAPFLLF

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=706, Percent_Identity=40.5099150141643, Blast_Score=508, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017871 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 92674; Mature: 92543

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKNKKVKPTAKVDDNATKDIACDPAHSIQVRGARVHNLKNVDVDLPRNALVVFTGISG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEECCCCCCCEECCCCEEEEEEECCC
SGKSSLAFGTLFAESQHRYLDSVSPYARRLIDQVDQPDVDSIEGLPPAVALQQQRGTPSV
CCCCCEEEHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCHH
RSSVGSVTTISNGLRMLYSRAGEYPAGQDILYADAFSPNTPDGACPTCSGIGRVFEVTEE
HHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
LLVPDNTKTIRERAIAAWPPAWQGQNLSRILTSLGYDIDKPWNTLPQKTRDWILFTDDTP
HHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCC
EVPVYPEYNIEQVRDAIKKGEKPNYKGTFTSAKNFVLHSFASTQSPRTKKRVSQFMQISE
CCCCCCCCCHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
CPECHGKKLKKESLSVKFAGLDIGELSQLTLTEMALKLQDAAKTKPNDNMPNREKAIVAQ
CHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RIASDILSRVEALTTLGLGYLSLERTTPTLSPGELQRLRLATQIRSKLFGVVYVLDEPSA
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCC
GLHPADTQALLGALDELTAAGNSLFIVEHDVSVIRHADWIVDVGPKAGTHGGEVIYSGPV
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCEEEECCCCCCCCCCEEEECCCC
AGLRDVAQSRTGQYLFETEGAVEHTPRKAKASLQLVNIERNNLQGLDVAFPLGVMTTVTG
HHHHHHHHHCCCCEEEECCCCHHCCCCHHHCEEEEEEEECCCCCCCCCHHHHHHHHHHCC
VSGSGKSSLVSQALVDLIYSELGQKTIIEAPTGEADLLEQELETQTSGKIANGMEHVSRL
CCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VTVDQKAIGRTPRSNLATYTGLFDHVRKLFAATPEAKARRYDAGRFSFNVKKGRCPNCEG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCCCC
VGFVSVELLFLPSVYSPCQVCHGQRYNDETLEITYRGKNIAEILDLTVESAYEFFVEESS
CCEEEEEEEECCCCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ILRALDALLKVGLGYLRLGQPATELSGGEAQRIKLATELQRTQRGDTLYILDEPTTGLHP
HHHHHHHHHHHCCCCEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
SDVSLLMAQLNGLVDAGNTVIMVEHDMQVASNSDWIIDIGPGAGDEGGLIVAEGTPAEVA
HHHHHHHHHHHHHEECCCEEEEEECCCEECCCCCEEEECCCCCCCCCCEEEECCCCHHHH
KSKASRTAPFLLF
HHHHHCCCCEEEC
>Mature Secondary Structure 
TTKNKKVKPTAKVDDNATKDIACDPAHSIQVRGARVHNLKNVDVDLPRNALVVFTGISG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEECCCCCCCEECCCCEEEEEEECCC
SGKSSLAFGTLFAESQHRYLDSVSPYARRLIDQVDQPDVDSIEGLPPAVALQQQRGTPSV
CCCCCEEEHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCHH
RSSVGSVTTISNGLRMLYSRAGEYPAGQDILYADAFSPNTPDGACPTCSGIGRVFEVTEE
HHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
LLVPDNTKTIRERAIAAWPPAWQGQNLSRILTSLGYDIDKPWNTLPQKTRDWILFTDDTP
HHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCC
EVPVYPEYNIEQVRDAIKKGEKPNYKGTFTSAKNFVLHSFASTQSPRTKKRVSQFMQISE
CCCCCCCCCHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
CPECHGKKLKKESLSVKFAGLDIGELSQLTLTEMALKLQDAAKTKPNDNMPNREKAIVAQ
CHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RIASDILSRVEALTTLGLGYLSLERTTPTLSPGELQRLRLATQIRSKLFGVVYVLDEPSA
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCC
GLHPADTQALLGALDELTAAGNSLFIVEHDVSVIRHADWIVDVGPKAGTHGGEVIYSGPV
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCEEEECCCCCCCCCCEEEECCCC
AGLRDVAQSRTGQYLFETEGAVEHTPRKAKASLQLVNIERNNLQGLDVAFPLGVMTTVTG
HHHHHHHHHCCCCEEEECCCCHHCCCCHHHCEEEEEEEECCCCCCCCCHHHHHHHHHHCC
VSGSGKSSLVSQALVDLIYSELGQKTIIEAPTGEADLLEQELETQTSGKIANGMEHVSRL
CCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VTVDQKAIGRTPRSNLATYTGLFDHVRKLFAATPEAKARRYDAGRFSFNVKKGRCPNCEG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCCCC
VGFVSVELLFLPSVYSPCQVCHGQRYNDETLEITYRGKNIAEILDLTVESAYEFFVEESS
CCEEEEEEEECCCCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ILRALDALLKVGLGYLRLGQPATELSGGEAQRIKLATELQRTQRGDTLYILDEPTTGLHP
HHHHHHHHHHHCCCCEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
SDVSLLMAQLNGLVDAGNTVIMVEHDMQVASNSDWIIDIGPGAGDEGGLIVAEGTPAEVA
HHHHHHHHHHHHHEECCCEEEEEECCCEECCCCCEEEECCCCCCCCCCEEEECCCCHHHH
KSKASRTAPFLLF
HHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8269961 [H]