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The map label for this gene is insF7 [C]

Identifier: 93005545

GI number: 93005545

Start: 844517

End: 845323

Strand: Reverse

Name: insF7 [C]

Synonym: Pcryo_0715

Alternate gene names: 93005545

Gene position: 845323-844517 (Counterclockwise)

Preceding gene: 93005546

Following gene: 93005544

Centisome position: 27.63

GC content: 43.0

Gene sequence:

>807_bases
TTGCTTAGTGTTAGTCCGCAAGCGGTTTATCAACACCGTATTCGGCAGCATGACAAAGCAAGCAGGTTTGCTGTCATCAA
AGACTGGGTGCAAGCGTATCGAATACTCATGCCTCGTATAGGGGGTCGGAAGTTATATTGGCTCATTAAGCCTAAGCTGA
TGGCTCATGGCATAAAGATTGGCCGTGATGGCTTCTTTGATTATCTAAGAGCACACCGCTTGTTAGTGATGCCTAAACGT
AGCTATACAAAGACAACCTTTAGTAAGCACTGGATGAAAAAACATCCCAATCTAACGAAAGATGCCCCTGCGCCTATCAA
GCCTGAACAAACCTTGGTGGCTGATATTACTTATGTCACATCCAAACAAGGGACGCACTACCTATCGTTAGTAACGGATG
GGTATTCAAGACAGATCATGGGGTATCATTTAAGTGAGAGTATGCCAGCGACTGAGGTTGTAAAAGCGCTTAAGATGGCA
GCTCAAAGGCGGCGTTATACTCATAAAGCGATTCATCACTCTGATAGAGGCCTTCAGTACTGTGCATCAGAGTATCAAGA
GGTGCTTAGAGCAAATAACATCTCACCGTCTATGACCGATGGCTATGATTGTTATCAAAATGCATTGGCTGAGCGCGTTA
ATGGGATTTTAAAGAATGAGTTCTTGTTGTATGAGTGCAATACGATGAGTGAGCTTAAACAGCTGATCGATGAGTCTATT
TATGTCTATAACCATATCAGACCGCATTTAAGTTTGAATATGAGAACACCTGCTGAGGTACATGACGGTTATTTATGTCC
TGCTTAA

Upstream 100 bases:

>100_bases
TTGAAAATGACTATGGAGAAAATGCTAGAAAAAAGTCTTCTACGGCATCCTTTGGAAACTCAAAACAGACAAACAAATAA
GTTTAGCTCAAGGATGCCGG

Downstream 100 bases:

>100_bases
TACAAAAAAGCCAGATACTCAGGGTATCTGGCTTAGCAAAAACTATCAATCTATTTTAGGACGGGACATCTATTTAATGA
ATCGTAGCGTTTTAAAGCTA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLSVSPQAVYQHRIRQHDKASRFAVIKDWVQAYRILMPRIGGRKLYWLIKPKLMAHGIKIGRDGFFDYLRAHRLLVMPKR
SYTKTTFSKHWMKKHPNLTKDAPAPIKPEQTLVADITYVTSKQGTHYLSLVTDGYSRQIMGYHLSESMPATEVVKALKMA
AQRRRYTHKAIHHSDRGLQYCASEYQEVLRANNISPSMTDGYDCYQNALAERVNGILKNEFLLYECNTMSELKQLIDESI
YVYNHIRPHLSLNMRTPAEVHDGYLCPA

Sequences:

>Translated_268_residues
MLSVSPQAVYQHRIRQHDKASRFAVIKDWVQAYRILMPRIGGRKLYWLIKPKLMAHGIKIGRDGFFDYLRAHRLLVMPKR
SYTKTTFSKHWMKKHPNLTKDAPAPIKPEQTLVADITYVTSKQGTHYLSLVTDGYSRQIMGYHLSESMPATEVVKALKMA
AQRRRYTHKAIHHSDRGLQYCASEYQEVLRANNISPSMTDGYDCYQNALAERVNGILKNEFLLYECNTMSELKQLIDESI
YVYNHIRPHLSLNMRTPAEVHDGYLCPA
>Mature_268_residues
MLSVSPQAVYQHRIRQHDKASRFAVIKDWVQAYRILMPRIGGRKLYWLIKPKLMAHGIKIGRDGFFDYLRAHRLLVMPKR
SYTKTTFSKHWMKKHPNLTKDAPAPIKPEQTLVADITYVTSKQGTHYLSLVTDGYSRQIMGYHLSESMPATEVVKALKMA
AQRRRYTHKAIHHSDRGLQYCASEYQEVLRANNISPSMTDGYDCYQNALAERVNGILKNEFLLYECNTMSELKQLIDESI
YVYNHIRPHLSLNMRTPAEVHDGYLCPA

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=186, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1788405, Length=174, Percent_Identity=31.6091954022989, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787263, Length=174, Percent_Identity=31.6091954022989, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786753, Length=174, Percent_Identity=31.6091954022989, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786570, Length=174, Percent_Identity=31.6091954022989, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786490, Length=174, Percent_Identity=31.6091954022989, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789981, Length=173, Percent_Identity=32.3699421965318, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31086; Mature: 31086

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVSPQAVYQHRIRQHDKASRFAVIKDWVQAYRILMPRIGGRKLYWLIKPKLMAHGIKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHCCCCC
GRDGFFDYLRAHRLLVMPKRSYTKTTFSKHWMKKHPNLTKDAPAPIKPEQTLVADITYVT
CCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHEEE
SKQGTHYLSLVTDGYSRQIMGYHLSESMPATEVVKALKMAAQRRRYTHKAIHHSDRGLQY
CCCCCEEEEEEECCCHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
CASEYQEVLRANNISPSMTDGYDCYQNALAERVNGILKNEFLLYECNTMSELKQLIDESI
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHH
YVYNHIRPHLSLNMRTPAEVHDGYLCPA
HHHHCCCCCEEECCCCCHHHCCCCCCCC
>Mature Secondary Structure
MLSVSPQAVYQHRIRQHDKASRFAVIKDWVQAYRILMPRIGGRKLYWLIKPKLMAHGIKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHCCCCC
GRDGFFDYLRAHRLLVMPKRSYTKTTFSKHWMKKHPNLTKDAPAPIKPEQTLVADITYVT
CCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHEEE
SKQGTHYLSLVTDGYSRQIMGYHLSESMPATEVVKALKMAAQRRRYTHKAIHHSDRGLQY
CCCCCEEEEEEECCCHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
CASEYQEVLRANNISPSMTDGYDCYQNALAERVNGILKNEFLLYECNTMSELKQLIDESI
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHH
YVYNHIRPHLSLNMRTPAEVHDGYLCPA
HHHHCCCCCEEECCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]