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The map label for this gene is hmp [H]

Identifier: 93005544

GI number: 93005544

Start: 842899

End: 844098

Strand: Reverse

Name: hmp [H]

Synonym: Pcryo_0714

Alternate gene names: 93005544

Gene position: 844098-842899 (Counterclockwise)

Preceding gene: 93005545

Following gene: 93005543

Centisome position: 27.59

GC content: 42.83

Gene sequence:

>1200_bases
ATGGCGTCACTACAAACATTAGCAATCGTCAAAGCAACGGTACCGGTACTCGAAGAGCATGGAACCGCGATTACTACTGT
ATTTTATAAGAATATGTTTCATGAGCATCCTGAACTACTTGATATTTTTAATGAAACCAATCAAAAGCTTGGTCGTCAAC
AGACTGCACTGGCAATGACGGTTTTGGCAGCGGCTAAACATCTAGAAAACTTAGCGACATTATTGCCGCAAGTGACGCAA
ATCAGCCATAAGCATCGCGCCTTACAAATCCTACCAGAGCACTACCCTATCGTTGGCAAGCATCTGCTTGCTGCCATCAA
GGAAGTATTGGGTGATGCAGCAACTGACGATATCCTTACGGCTTGGGCAGAAGCTTATGATGAGATTGCCTCGATATTTA
TCCAAATCGAGCATGGTATGTATGAGCAAGCAATGTGGCAAGGCTTTGCACCGTTTATAGTAACGGCAAAAGCAGAAGCA
GCGACTGATATCGCCGCCTTTACCGTCGTCCCGGTAAATGACCATTCAGTAAACAATCAGACTATCGATTTAAGCAAGAT
TAAACTGTCTGCCGGTCAATACATTACCGTAAAAACAGACCCAGCAGAAAGCGAACATATTGCTCTGCGTCACTACTCTT
TGTACTCAGCCAATAGCGATCAAGGTATCCAGTTTGCAGTTAGACGTGACAATCGCAATGAGCATCATGGTCTAGTGTCT
AATTATTTACATGATCATCTAGCCATCGGTGACACCGTTTTATTGTCGGCACCGGCTGGTGATTTTGAGCTAGACCAAGA
TTTGGTACAGCAAAACGATATTCCCTTGGTACTGATCAGTGCTGGCGTTGGCGTGACACCTATTTTATCCATGTTAGAAG
CTCAAGTTACCGCCAATCCAAAACGTCCTATCGTTTGGGTTTATGCTTGCCAAAACCGAGAGCATCATGCTTTTGATAGT
GAAGTTAATAAACTATTGGCTACTGCGACAAACGTAGAAAAGCACATTTTTTACTTTGAGTCTGGGCAGATTCTGAATGA
AGCTTGGCTTAGCAATTTGCCTAAACTTGCTGATATTTATGTTTGTGGTTCCATGCCTTTTATGGAAAGCATTATTGATA
GCCTGATCATCCTTGACCATGTCCTTAATAACATTCATTACGAACCCTTTGGTCCCAAAATGAGTATAGAGCTGGCTTAA

Upstream 100 bases:

>100_bases
TCATTCGGCGGTTCAGAATTTTGATTATCGTTATTAATTTCGTTCATTAATCTTAAATCACTAAATACTATCAATGTGAA
TATTCACTAAAGGATCCACA

Downstream 100 bases:

>100_bases
GGTTATAAGCAATTGTTAATGACAAAATAGTATTACTGGGATGGTTTTTTGAAGCTTCTGCATCGTTTTCTTCGAGCAAG
CGATAAAAAACCATCTCGGT

Product: globin

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MASLQTLAIVKATVPVLEEHGTAITTVFYKNMFHEHPELLDIFNETNQKLGRQQTALAMTVLAAAKHLENLATLLPQVTQ
ISHKHRALQILPEHYPIVGKHLLAAIKEVLGDAATDDILTAWAEAYDEIASIFIQIEHGMYEQAMWQGFAPFIVTAKAEA
ATDIAAFTVVPVNDHSVNNQTIDLSKIKLSAGQYITVKTDPAESEHIALRHYSLYSANSDQGIQFAVRRDNRNEHHGLVS
NYLHDHLAIGDTVLLSAPAGDFELDQDLVQQNDIPLVLISAGVGVTPILSMLEAQVTANPKRPIVWVYACQNREHHAFDS
EVNKLLATATNVEKHIFYFESGQILNEAWLSNLPKLADIYVCGSMPFMESIIDSLIILDHVLNNIHYEPFGPKMSIELA

Sequences:

>Translated_399_residues
MASLQTLAIVKATVPVLEEHGTAITTVFYKNMFHEHPELLDIFNETNQKLGRQQTALAMTVLAAAKHLENLATLLPQVTQ
ISHKHRALQILPEHYPIVGKHLLAAIKEVLGDAATDDILTAWAEAYDEIASIFIQIEHGMYEQAMWQGFAPFIVTAKAEA
ATDIAAFTVVPVNDHSVNNQTIDLSKIKLSAGQYITVKTDPAESEHIALRHYSLYSANSDQGIQFAVRRDNRNEHHGLVS
NYLHDHLAIGDTVLLSAPAGDFELDQDLVQQNDIPLVLISAGVGVTPILSMLEAQVTANPKRPIVWVYACQNREHHAFDS
EVNKLLATATNVEKHIFYFESGQILNEAWLSNLPKLADIYVCGSMPFMESIIDSLIILDHVLNNIHYEPFGPKMSIELA
>Mature_398_residues
ASLQTLAIVKATVPVLEEHGTAITTVFYKNMFHEHPELLDIFNETNQKLGRQQTALAMTVLAAAKHLENLATLLPQVTQI
SHKHRALQILPEHYPIVGKHLLAAIKEVLGDAATDDILTAWAEAYDEIASIFIQIEHGMYEQAMWQGFAPFIVTAKAEAA
TDIAAFTVVPVNDHSVNNQTIDLSKIKLSAGQYITVKTDPAESEHIALRHYSLYSANSDQGIQFAVRRDNRNEHHGLVSN
YLHDHLAIGDTVLLSAPAGDFELDQDLVQQNDIPLVLISAGVGVTPILSMLEAQVTANPKRPIVWVYACQNREHHAFDSE
VNKLLATATNVEKHIFYFESGQILNEAWLSNLPKLADIYVCGSMPFMESIIDSLIILDHVLNNIHYEPFGPKMSIELA

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=412, Percent_Identity=37.378640776699, Blast_Score=248, Evalue=5e-67,
Organism=Saccharomyces cerevisiae, GI6321673, Length=400, Percent_Identity=53.25, Blast_Score=404, Evalue=1e-113,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR001834
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 44260; Mature: 44129

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLQTLAIVKATVPVLEEHGTAITTVFYKNMFHEHPELLDIFNETNQKLGRQQTALAMT
CCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHH
VLAAAKHLENLATLLPQVTQISHKHRALQILPEHYPIVGKHLLAAIKEVLGDAATDDILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
AWAEAYDEIASIFIQIEHGMYEQAMWQGFAPFIVTAKAEAATDIAAFTVVPVNDHSVNNQ
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCHHCCCEEEEEEEECCCCCCCCC
TIDLSKIKLSAGQYITVKTDPAESEHIALRHYSLYSANSDQGIQFAVRRDNRNEHHGLVS
EEEEEEEEECCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHH
NYLHDHLAIGDTVLLSAPAGDFELDQDLVQQNDIPLVLISAGVGVTPILSMLEAQVTANP
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
KRPIVWVYACQNREHHAFDSEVNKLLATATNVEKHIFYFESGQILNEAWLSNLPKLADIY
CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHEEEEEECCCHHHHHHHCCCCCCEEEE
VCGSMPFMESIIDSLIILDHVLNNIHYEPFGPKMSIELA
EECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
>Mature Secondary Structure 
ASLQTLAIVKATVPVLEEHGTAITTVFYKNMFHEHPELLDIFNETNQKLGRQQTALAMT
CCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHH
VLAAAKHLENLATLLPQVTQISHKHRALQILPEHYPIVGKHLLAAIKEVLGDAATDDILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
AWAEAYDEIASIFIQIEHGMYEQAMWQGFAPFIVTAKAEAATDIAAFTVVPVNDHSVNNQ
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCHHCCCEEEEEEEECCCCCCCCC
TIDLSKIKLSAGQYITVKTDPAESEHIALRHYSLYSANSDQGIQFAVRRDNRNEHHGLVS
EEEEEEEEECCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHH
NYLHDHLAIGDTVLLSAPAGDFELDQDLVQQNDIPLVLISAGVGVTPILSMLEAQVTANP
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
KRPIVWVYACQNREHHAFDSEVNKLLATATNVEKHIFYFESGQILNEAWLSNLPKLADIY
CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHEEEEEECCCHHHHHHHCCCCCCEEEE
VCGSMPFMESIIDSLIILDHVLNNIHYEPFGPKMSIELA
EECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10484179; 11058132 [H]