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The map label for this gene is moaA [H]

Identifier: 93005542

GI number: 93005542

Start: 840011

End: 841114

Strand: Reverse

Name: moaA [H]

Synonym: Pcryo_0712

Alternate gene names: 93005542

Gene position: 841114-840011 (Counterclockwise)

Preceding gene: 93005543

Following gene: 93005541

Centisome position: 27.49

GC content: 43.03

Gene sequence:

>1104_bases
ATGAACCATCTTGCCCCCACCGTAGGAAATGCTCAACTGTATTCGCCTACTGCTGCATCTAGTTTTTTTGATGATCATTT
ACCATCGAAATTGGCAGTTTTGTCTACTGATTCTGCAGTTAACTTAGCTCAACCATTAACAGATGGCTTTGCACGACGTC
TGACCTATTTGCGTTTATCGATTACTGATTTCTGTAATTTTCGCTGTGAGTATTGCTTGCCCAATGGCTATCAAGGCAAA
CCTCCCCAAGATGAGCTTAGTGTCGCTGAAATTGCTACGTTAATCCGCGGATTTGCCCAAGTTGGCACCAAAAAAGTCAG
GATTACGGGCGGTGAGCCTTCTATACGCCGTGATGTGGTAGACATTATTAAAACAATCAAAAACACTGAAGGCATTGAAA
CCGTTGCCATGACCAGTAATGGTTATAAGCTTGGTAAGCACCTGGCTAGTTGGCAGGCAGCTGGACTAAATCAGCTTAAT
ATCAGTATGGACAGCTTTGATGCCGCTACTTTCCATAAGATGACTGGCTTTGATATGTTGCCGCAACTCTTGGCTGATAT
GGATACCTTGCTGGCAACCACCGATATTAAGCTTAAAATAAACAGCATTCTGATGGCAGAAACTGCCTTTGAAAACTTAA
TGAATGCCATTGATTATGTCAAAGATAGAGCAGTCACTTATCGCTTTATTGAATTTATGCAGACCAGTGACAACAGCGAT
TTGTTTTTTGCTCAGCATGCGCAAACCGACATCATTACCAATTATCTGATAGAAGACGGCTGGCAAACTCATGAACGCGG
CAGTAACGACGGTCCAGCAATTGAGTACAGTCATCCTGATTATAAAGGGCGTATCGGACTGATTGCCCCATATGCAGCCC
ATTTTTGTGACAGCTGTAATCGCCTGCGGGTTAGCAGTCAAGGCAAAGTGCATCTGTGCTTATTTGATCAAGGCAATTAC
GACATTCGTGAGCATTTGCAGCAAGATGATGTTGCAGGACTGGTCAGTACTTTACATAGTTTTATGCCCATTAAACCTGA
GCACCATCATCTTCATGACTCGAACAGTGGCATTATGAATAACTTGTCGATGATTGGTGGTTAA

Upstream 100 bases:

>100_bases
AGTTACTCGGTCATATTTATACCTGAATAGCCTATTTCACTCACAACCTGAGGCAACGCTTAAAAGTACACACTATATTT
TATATTAATGGTAATCATCT

Downstream 100 bases:

>100_bases
TTTATTTATCAGCAATATTTTTCATAATAAGCATATTTATCAAGGAACATTCATGAGCAAGCTGCAAGCACCTTTTACCC
CACTTAATATCGCCATCTTA

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNHLAPTVGNAQLYSPTAASSFFDDHLPSKLAVLSTDSAVNLAQPLTDGFARRLTYLRLSITDFCNFRCEYCLPNGYQGK
PPQDELSVAEIATLIRGFAQVGTKKVRITGGEPSIRRDVVDIIKTIKNTEGIETVAMTSNGYKLGKHLASWQAAGLNQLN
ISMDSFDAATFHKMTGFDMLPQLLADMDTLLATTDIKLKINSILMAETAFENLMNAIDYVKDRAVTYRFIEFMQTSDNSD
LFFAQHAQTDIITNYLIEDGWQTHERGSNDGPAIEYSHPDYKGRIGLIAPYAAHFCDSCNRLRVSSQGKVHLCLFDQGNY
DIREHLQQDDVAGLVSTLHSFMPIKPEHHHLHDSNSGIMNNLSMIGG

Sequences:

>Translated_367_residues
MNHLAPTVGNAQLYSPTAASSFFDDHLPSKLAVLSTDSAVNLAQPLTDGFARRLTYLRLSITDFCNFRCEYCLPNGYQGK
PPQDELSVAEIATLIRGFAQVGTKKVRITGGEPSIRRDVVDIIKTIKNTEGIETVAMTSNGYKLGKHLASWQAAGLNQLN
ISMDSFDAATFHKMTGFDMLPQLLADMDTLLATTDIKLKINSILMAETAFENLMNAIDYVKDRAVTYRFIEFMQTSDNSD
LFFAQHAQTDIITNYLIEDGWQTHERGSNDGPAIEYSHPDYKGRIGLIAPYAAHFCDSCNRLRVSSQGKVHLCLFDQGNY
DIREHLQQDDVAGLVSTLHSFMPIKPEHHHLHDSNSGIMNNLSMIGG
>Mature_367_residues
MNHLAPTVGNAQLYSPTAASSFFDDHLPSKLAVLSTDSAVNLAQPLTDGFARRLTYLRLSITDFCNFRCEYCLPNGYQGK
PPQDELSVAEIATLIRGFAQVGTKKVRITGGEPSIRRDVVDIIKTIKNTEGIETVAMTSNGYKLGKHLASWQAAGLNQLN
ISMDSFDAATFHKMTGFDMLPQLLADMDTLLATTDIKLKINSILMAETAFENLMNAIDYVKDRAVTYRFIEFMQTSDNSD
LFFAQHAQTDIITNYLIEDGWQTHERGSNDGPAIEYSHPDYKGRIGLIAPYAAHFCDSCNRLRVSSQGKVHLCLFDQGNY
DIREHLQQDDVAGLVSTLHSFMPIKPEHHHLHDSNSGIMNNLSMIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=285, Percent_Identity=32.280701754386, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI22027536, Length=285, Percent_Identity=32.280701754386, Blast_Score=175, Evalue=6e-44,
Organism=Escherichia coli, GI1786999, Length=329, Percent_Identity=45.2887537993921, Blast_Score=312, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI32566331, Length=293, Percent_Identity=35.8361774744027, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI32566329, Length=293, Percent_Identity=35.8361774744027, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17561210, Length=332, Percent_Identity=33.1325301204819, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI28574490, Length=323, Percent_Identity=33.7461300309598, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI28574488, Length=330, Percent_Identity=33.3333333333333, Blast_Score=193, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 40772; Mature: 40772

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLAPTVGNAQLYSPTAASSFFDDHLPSKLAVLSTDSAVNLAQPLTDGFARRLTYLRLS
CCCCCCCCCCCEEECCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHEE
ITDFCNFRCEYCLPNGYQGKPPQDELSVAEIATLIRGFAQVGTKKVRITGGEPSIRRDVV
HHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHH
DIIKTIKNTEGIETVAMTSNGYKLGKHLASWQAAGLNQLNISMDSFDAATFHKMTGFDML
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCHHHH
PQLLADMDTLLATTDIKLKINSILMAETAFENLMNAIDYVKDRAVTYRFIEFMQTSDNSD
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LFFAQHAQTDIITNYLIEDGWQTHERGSNDGPAIEYSHPDYKGRIGLIAPYAAHFCDSCN
EEEEECCCHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCCCCCCEEEECHHHHHHHCCCC
RLRVSSQGKVHLCLFDQGNYDIREHLQQDDVAGLVSTLHSFMPIKPEHHHLHDSNSGIMN
EEEECCCCCEEEEEECCCCCHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
NLSMIGG
HHHHCCC
>Mature Secondary Structure
MNHLAPTVGNAQLYSPTAASSFFDDHLPSKLAVLSTDSAVNLAQPLTDGFARRLTYLRLS
CCCCCCCCCCCEEECCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHEE
ITDFCNFRCEYCLPNGYQGKPPQDELSVAEIATLIRGFAQVGTKKVRITGGEPSIRRDVV
HHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHH
DIIKTIKNTEGIETVAMTSNGYKLGKHLASWQAAGLNQLNISMDSFDAATFHKMTGFDML
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCHHHH
PQLLADMDTLLATTDIKLKINSILMAETAFENLMNAIDYVKDRAVTYRFIEFMQTSDNSD
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LFFAQHAQTDIITNYLIEDGWQTHERGSNDGPAIEYSHPDYKGRIGLIAPYAAHFCDSCN
EEEEECCCHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCCCCCCEEEECHHHHHHHCCCC
RLRVSSQGKVHLCLFDQGNYDIREHLQQDDVAGLVSTLHSFMPIKPEHHHLHDSNSGIMN
EEEECCCCCEEEEEECCCCCHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
NLSMIGG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA