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The map label for this gene is moaB [H]

Identifier: 93005541

GI number: 93005541

Start: 839428

End: 839958

Strand: Reverse

Name: moaB [H]

Synonym: Pcryo_0711

Alternate gene names: 93005541

Gene position: 839958-839428 (Counterclockwise)

Preceding gene: 93005542

Following gene: 93005540

Centisome position: 27.45

GC content: 49.15

Gene sequence:

>531_bases
ATGAGCAAGCTGCAAGCACCTTTTACCCCACTTAATATCGCCATCTTAACGGTTTCTGACAGTCGTACGATGGCAGAAGA
TAGCTCAGGGCAGTATCTGGTCGATCAGTTAACCGCAGCAGGGCATCAGCTTGCTGATCGTCAACTGATTACCGACGATA
TCTATAAGATTAGAGCCGTTGTCAGCGGCTGGATTGCGGACCCAAATGTTCATGCAGTGATTACCACTGGCGGTACGGGG
TTTTATATTAGAGACAGCATTCCAGAGGCAGTCAGCGTCTTGTTTGACAAGTCAGTAGATGGTTTTGGCGAGATGTTCCG
CTTAATCTCAAAAGATGATATCGGCATGTCTACCATCCAATCTCGCGCTGTAGCTGGTATGGCAAATGGTACAGGCATTT
TTTGCCTACCCGGCTCATCAGGCGCTTGCCGTACTGCTTGGGAAGGCATCTTACAAGAGCAGCTGGATAGCCGTACGCGC
CCATGCAATTTTGTTCCGCACTTTATGCGTACCAACCCCGGTCACGATTAA

Upstream 100 bases:

>100_bases
GACTCGAACAGTGGCATTATGAATAACTTGTCGATGATTGGTGGTTAATTTATTTATCAGCAATATTTTTCATAATAAGC
ATATTTATCAAGGAACATTC

Downstream 100 bases:

>100_bases
TCATGACAGATGCTGTAAATACCTTAAAAAGTGTAAATAGCTCAAGCGATATAGATCACTTGAATCGCTTAGCAGGTATC
GTCATCTTAGCAGGCGGTGC

Product: molybdopterin binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSKLQAPFTPLNIAILTVSDSRTMAEDSSGQYLVDQLTAAGHQLADRQLITDDIYKIRAVVSGWIADPNVHAVITTGGTG
FYIRDSIPEAVSVLFDKSVDGFGEMFRLISKDDIGMSTIQSRAVAGMANGTGIFCLPGSSGACRTAWEGILQEQLDSRTR
PCNFVPHFMRTNPGHD

Sequences:

>Translated_176_residues
MSKLQAPFTPLNIAILTVSDSRTMAEDSSGQYLVDQLTAAGHQLADRQLITDDIYKIRAVVSGWIADPNVHAVITTGGTG
FYIRDSIPEAVSVLFDKSVDGFGEMFRLISKDDIGMSTIQSRAVAGMANGTGIFCLPGSSGACRTAWEGILQEQLDSRTR
PCNFVPHFMRTNPGHD
>Mature_175_residues
SKLQAPFTPLNIAILTVSDSRTMAEDSSGQYLVDQLTAAGHQLADRQLITDDIYKIRAVVSGWIADPNVHAVITTGGTGF
YIRDSIPEAVSVLFDKSVDGFGEMFRLISKDDIGMSTIQSRAVAGMANGTGIFCLPGSSGACRTAWEGILQEQLDSRTRP
CNFVPHFMRTNPGHD

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=146, Percent_Identity=30.8219178082192, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI66932975, Length=146, Percent_Identity=30.8219178082192, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787000, Length=170, Percent_Identity=54.1176470588235, Blast_Score=196, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19039; Mature: 18908

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLQAPFTPLNIAILTVSDSRTMAEDSSGQYLVDQLTAAGHQLADRQLITDDIYKIRAV
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VSGWIADPNVHAVITTGGTGFYIRDSIPEAVSVLFDKSVDGFGEMFRLISKDDIGMSTIQ
HHHHCCCCCCEEEEEECCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHH
SRAVAGMANGTGIFCLPGSSGACRTAWEGILQEQLDSRTRPCNFVPHFMRTNPGHD
HHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
SKLQAPFTPLNIAILTVSDSRTMAEDSSGQYLVDQLTAAGHQLADRQLITDDIYKIRAV
CCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VSGWIADPNVHAVITTGGTGFYIRDSIPEAVSVLFDKSVDGFGEMFRLISKDDIGMSTIQ
HHHHCCCCCCEEEEEECCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHH
SRAVAGMANGTGIFCLPGSSGACRTAWEGILQEQLDSRTRPCNFVPHFMRTNPGHD
HHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]