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The map label for this gene is ribB [H]

Identifier: 93004933

GI number: 93004933

Start: 117512

End: 118624

Strand: Reverse

Name: ribB [H]

Synonym: Pcryo_0102

Alternate gene names: 93004933

Gene position: 118624-117512 (Counterclockwise)

Preceding gene: 93004934

Following gene: 93004926

Centisome position: 3.88

GC content: 47.08

Gene sequence:

>1113_bases
ATGAGTTTAAATACGATTCCTGAGATTATCGAAGACATTCGTGCAGGTAAAATGGTCATCTTGATGGATGATGAAGACCG
CGAAAACGAAGGCGATATTATCATGGCAGCGACCCACGTGCGCCCTGAAGATATCAACTTTATGATTACTCATGCACGTG
GCTTGGTCTGTTTGACCTTGTCACAAGCACGTTGCCAGCAGTTGGCACTGCCACTCATGTCTGACCGTAATGAAGCAAAA
TTTAGTACCAATTTTACCGTTTCTATTGAAGCGGCTGAAGGCGTGACTACGGGTATTTCAGCCGCTGACCGCGCGCGTAC
CATTCAAGCAGCGGTCTCCTCTTCTGCAAAACCAGAAGACATCGTTCAGCCTGGGCATATTTTCCCAATCATGGCACAGA
ATGGTGGCGTCTTACATCGTGCCGGACATACCGAAGCAGGTTGTGATTTGGCACGTCTTGCCGGACTTGAGCCAGCAGCG
GTGATTGTAGAGATTATCAATGCGGATGGCACCATGGCACGCCGTGATGATCTTGAAGTATTTGCAAAGGAACATGATTT
AAAAATTGGTACGATTGCTGATTTGATTAACTACCGTATTGCTAATGAGCAAACCGTCGAAGAGATTGCCTCGCATCCGT
TTGAGACCGAGTATGGCACTTTTACCTTACATCGTTTCCGTGAGTTCGGTGCGACTGAAACCCATTTAGCTTTGGTTAAA
GGCGATGTGAGCCAAGGTATTAGCACCGTTCGCGTCCATGGTTTCCATCCATTACGTGACTTGTTTGCTGCCAAAAATGA
TACCACTGGTCGTAGCGGCTGGAGCGTACGCTCAGCATTAGAAGAGATCAGTGCATCAGAGCGTGGTGTCTTGGTTTGGA
TTGGCAATCATGAGCCGACTGACTTGGGCGATGCTTTGGATAAGGCGGCATTGAATGAAGCTCTATCTACCATCACACAG
CAACCATATCGCAGTATTGGTGTTGGCGCACAGATTTTGCGTCATTTAGGGGTACGTGATATGCGCCTCTTGTCCTCACC
GATGAAGTTTTATGCCTTATCAGGTTTTGATTTGAACGTGGTTGATTTTGTCCATGCACCAAAGCAAGATTAA

Upstream 100 bases:

>100_bases
GCCGCAACAGCGCTTTGTCGCATCTACTGCTACAATAGGCAGATAACACTTTATATCCCATATTGACACCTATTTATACA
ATAAAATATTGAGATCTACT

Downstream 100 bases:

>100_bases
TAGGCTTAATTAATAGAAACTTATTATCAATAAAAAAGGCGCATCAGCTTAGATTGATGCGCCTTTTTTCTTATTTTCTC
AAAGCTTAATCACAAAGCAT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSLNTIPEIIEDIRAGKMVILMDDEDRENEGDIIMAATHVRPEDINFMITHARGLVCLTLSQARCQQLALPLMSDRNEAK
FSTNFTVSIEAAEGVTTGISAADRARTIQAAVSSSAKPEDIVQPGHIFPIMAQNGGVLHRAGHTEAGCDLARLAGLEPAA
VIVEIINADGTMARRDDLEVFAKEHDLKIGTIADLINYRIANEQTVEEIASHPFETEYGTFTLHRFREFGATETHLALVK
GDVSQGISTVRVHGFHPLRDLFAAKNDTTGRSGWSVRSALEEISASERGVLVWIGNHEPTDLGDALDKAALNEALSTITQ
QPYRSIGVGAQILRHLGVRDMRLLSSPMKFYALSGFDLNVVDFVHAPKQD

Sequences:

>Translated_370_residues
MSLNTIPEIIEDIRAGKMVILMDDEDRENEGDIIMAATHVRPEDINFMITHARGLVCLTLSQARCQQLALPLMSDRNEAK
FSTNFTVSIEAAEGVTTGISAADRARTIQAAVSSSAKPEDIVQPGHIFPIMAQNGGVLHRAGHTEAGCDLARLAGLEPAA
VIVEIINADGTMARRDDLEVFAKEHDLKIGTIADLINYRIANEQTVEEIASHPFETEYGTFTLHRFREFGATETHLALVK
GDVSQGISTVRVHGFHPLRDLFAAKNDTTGRSGWSVRSALEEISASERGVLVWIGNHEPTDLGDALDKAALNEALSTITQ
QPYRSIGVGAQILRHLGVRDMRLLSSPMKFYALSGFDLNVVDFVHAPKQD
>Mature_369_residues
SLNTIPEIIEDIRAGKMVILMDDEDRENEGDIIMAATHVRPEDINFMITHARGLVCLTLSQARCQQLALPLMSDRNEAKF
STNFTVSIEAAEGVTTGISAADRARTIQAAVSSSAKPEDIVQPGHIFPIMAQNGGVLHRAGHTEAGCDLARLAGLEPAAV
IVEIINADGTMARRDDLEVFAKEHDLKIGTIADLINYRIANEQTVEEIASHPFETEYGTFTLHRFREFGATETHLALVKG
DVSQGISTVRVHGFHPLRDLFAAKNDTTGRSGWSVRSALEEISASERGVLVWIGNHEPTDLGDALDKAALNEALSTITQQ
PYRSIGVGAQILRHLGVRDMRLLSSPMKFYALSGFDLNVVDFVHAPKQD

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=192, Percent_Identity=51.5625, Blast_Score=206, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=44.3349753694581, Blast_Score=175, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40401; Mature: 40270

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNTIPEIIEDIRAGKMVILMDDEDRENEGDIIMAATHVRPEDINFMITHARGLVCLTL
CCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEE
SQARCQQLALPLMSDRNEAKFSTNFTVSIEAAEGVTTGISAADRARTIQAAVSSSAKPED
CHHHHHHHHCHHHCCCCCCEEECEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHH
IVQPGHIFPIMAQNGGVLHRAGHTEAGCDLARLAGLEPAAVIVEIINADGTMARRDDLEV
HCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCHHHHHHEEECCCCCCCCHHHHHH
FAKEHDLKIGTIADLINYRIANEQTVEEIASHPFETEYGTFTLHRFREFGATETHLALVK
HHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEEEE
GDVSQGISTVRVHGFHPLRDLFAAKNDTTGRSGWSVRSALEEISASERGVLVWIGNHEPT
CCHHCCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCC
DLGDALDKAALNEALSTITQQPYRSIGVGAQILRHLGVRDMRLLSSPMKFYALSGFDLNV
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHCCCCEEEECCCCCCH
VDFVHAPKQD
HHHCCCCCCC
>Mature Secondary Structure 
SLNTIPEIIEDIRAGKMVILMDDEDRENEGDIIMAATHVRPEDINFMITHARGLVCLTL
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEE
SQARCQQLALPLMSDRNEAKFSTNFTVSIEAAEGVTTGISAADRARTIQAAVSSSAKPED
CHHHHHHHHCHHHCCCCCCEEECEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHH
IVQPGHIFPIMAQNGGVLHRAGHTEAGCDLARLAGLEPAAVIVEIINADGTMARRDDLEV
HCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCHHHHHHEEECCCCCCCCHHHHHH
FAKEHDLKIGTIADLINYRIANEQTVEEIASHPFETEYGTFTLHRFREFGATETHLALVK
HHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEEEE
GDVSQGISTVRVHGFHPLRDLFAAKNDTTGRSGWSVRSALEEISASERGVLVWIGNHEPT
CCHHCCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCC
DLGDALDKAALNEALSTITQQPYRSIGVGAQILRHLGVRDMRLLSSPMKFYALSGFDLNV
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHCCCCEEEECCCCCCH
VDFVHAPKQD
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]