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The map label for this gene is ygbM [C]

Identifier: 92115296

GI number: 92115296

Start: 3546464

End: 3547252

Strand: Direct

Name: ygbM [C]

Synonym: Csal_3181

Alternate gene names: 92115296

Gene position: 3546464-3547252 (Clockwise)

Preceding gene: 92115295

Following gene: 92115304

Centisome position: 95.94

GC content: 65.78

Gene sequence:

>789_bases
ATGCCCCGCTTTGCCGCCAACCTGTCCATGATGTTCAACGAGGAGCCCTTCATGGAGCGCTTCGCCGCGGCCGCCGCCTG
CGGCTTCGAAGGGGTCGAGTTCCTGTTCCCCTATGCGTTCGAGGCCGATGACATCGCTGCCGAGTTGAGACGTCATGGCT
TGCAGCAGGCGCTGTTCAACCTGCCGCCGGGCGACTGGGACGCCGGCGAGCGCGGCATCGCCGCCCTGCCGGGGCGCGAG
GCGGAGTTCCGCGACAGCGTCGAGACCGCGATTCGTTACGCCCGGGCGCTGAACTGTCCGCGCCTGCATGCCATGGCAGG
GCTGGCCCCCGAGGATGTGGCACGGGAAACATGGCGCGAGGTGTATCTGGAAAACCTGCGCCATGCCGCCCGCCGCCTCG
CCGAACACGACCTCGAATTGCTGATCGAGCCCATCAATACCCGCGACATGCCGGGATACTGCCTCAACCATCAGGCCGAG
GGGCACGCCATCGTGGCCGAACTGGGCGAGCCCAACGTCAAGGTACAGATGGATTTCTACCACACCCAGATCATGGACGG
GGACCTCTGGACGACCTACCGGCGTCATCGCGCAGGGGTCGGCCACATTCAGATCGCCGGCGTGCCCGAGCGTCACGAAC
CCGATACCGGGGAAGTGAATTATCCGTGGCTTTTCCAACAGTTGGACGCAGACGGGTTCGAGGGCTGGATCGGCTGTGAA
TACAAGCCCCGCGCCGGCACCCGGGCGGGACTGGGATGGTTCGAGGCGTGGAAACGGCCAGCCGGCTAG

Upstream 100 bases:

>100_bases
GCGCCAGCACGACGTACGCACCCTGGGCGAAGCGGAAATCGATGAGCTTCGTCAGGCCTTCGGCGCCCACTGGTAAGCAT
TTTCTGAAAGGAGTCTCCCC

Downstream 100 bases:

>100_bases
CGGCCGAGACGCTGGCGGGCGCCGGCGTTGGCACGTGCGCCGGAGCCCGCCAGGACACTCAGAACGCGTAGGTCAGCGTC
GAGGTCACCCGTCGTGGTTC

Product: hydroxypyruvate isomerase

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPRFAANLSMMFNEEPFMERFAAAAACGFEGVEFLFPYAFEADDIAAELRRHGLQQALFNLPPGDWDAGERGIAALPGRE
AEFRDSVETAIRYARALNCPRLHAMAGLAPEDVARETWREVYLENLRHAARRLAEHDLELLIEPINTRDMPGYCLNHQAE
GHAIVAELGEPNVKVQMDFYHTQIMDGDLWTTYRRHRAGVGHIQIAGVPERHEPDTGEVNYPWLFQQLDADGFEGWIGCE
YKPRAGTRAGLGWFEAWKRPAG

Sequences:

>Translated_262_residues
MPRFAANLSMMFNEEPFMERFAAAAACGFEGVEFLFPYAFEADDIAAELRRHGLQQALFNLPPGDWDAGERGIAALPGRE
AEFRDSVETAIRYARALNCPRLHAMAGLAPEDVARETWREVYLENLRHAARRLAEHDLELLIEPINTRDMPGYCLNHQAE
GHAIVAELGEPNVKVQMDFYHTQIMDGDLWTTYRRHRAGVGHIQIAGVPERHEPDTGEVNYPWLFQQLDADGFEGWIGCE
YKPRAGTRAGLGWFEAWKRPAG
>Mature_261_residues
PRFAANLSMMFNEEPFMERFAAAAACGFEGVEFLFPYAFEADDIAAELRRHGLQQALFNLPPGDWDAGERGIAALPGREA
EFRDSVETAIRYARALNCPRLHAMAGLAPEDVARETWREVYLENLRHAARRLAEHDLELLIEPINTRDMPGYCLNHQAEG
HAIVAELGEPNVKVQMDFYHTQIMDGDLWTTYRRHRAGVGHIQIAGVPERHEPDTGEVNYPWLFQQLDADGFEGWIGCEY
KPRAGTRAGLGWFEAWKRPAG

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=265, Percent_Identity=47.5471698113208, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=47.3251028806584, Blast_Score=209, Evalue=3e-54,
Organism=Escherichia coli, GI1789095, Length=258, Percent_Identity=50.7751937984496, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1786718, Length=258, Percent_Identity=46.8992248062016, Blast_Score=254, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI17552022, Length=254, Percent_Identity=38.5826771653543, Blast_Score=190, Evalue=6e-49,
Organism=Drosophila melanogaster, GI17530883, Length=255, Percent_Identity=37.2549019607843, Blast_Score=177, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 29668; Mature: 29536

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLSMMFNEEPFMERFAAAAACGFEGVEFLFPYAFEADDIAAELRRHGLQQALFN
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
LPPGDWDAGERGIAALPGREAEFRDSVETAIRYARALNCPRLHAMAGLAPEDVARETWRE
CCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHH
VYLENLRHAARRLAEHDLELLIEPINTRDMPGYCLNHQAEGHAIVAELGEPNVKVQMDFY
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEECCCCCCCEEEEECCCCCEEEEEEEE
HTQIMDGDLWTTYRRHRAGVGHIQIAGVPERHEPDTGEVNYPWLFQQLDADGFEGWIGCE
EHEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCE
YKPRAGTRAGLGWFEAWKRPAG
ECCCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
PRFAANLSMMFNEEPFMERFAAAAACGFEGVEFLFPYAFEADDIAAELRRHGLQQALFN
CCHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
LPPGDWDAGERGIAALPGREAEFRDSVETAIRYARALNCPRLHAMAGLAPEDVARETWRE
CCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHH
VYLENLRHAARRLAEHDLELLIEPINTRDMPGYCLNHQAEGHAIVAELGEPNVKVQMDFY
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEECCCCCCCEEEEECCCCCEEEEEEEE
HTQIMDGDLWTTYRRHRAGVGHIQIAGVPERHEPDTGEVNYPWLFQQLDADGFEGWIGCE
EHEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCE
YKPRAGTRAGLGWFEAWKRPAG
ECCCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]