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The map label for this gene is siaT [H]

Identifier: 92115254

GI number: 92115254

Start: 3495262

End: 3496545

Strand: Direct

Name: siaT [H]

Synonym: Csal_3139

Alternate gene names: 92115254

Gene position: 3495262-3496545 (Clockwise)

Preceding gene: 92115253

Following gene: 92115256

Centisome position: 94.55

GC content: 64.64

Gene sequence:

>1284_bases
ATGCTAACTTGGCTAGCCGTGATCATGCTCGTGTTGCTGCTGCTCGGGTTCCCCATGATGGTTCCCCTGGCGGCGGGCAC
GCTGTTCATGATGTTCACCGGCATGACGTTTTTCGGGCCCGATCAGGCCGTGAGCTGGATGATCAACGGTATCGGCAGTT
GGGTACTCGCCGCCGTGCCCATGTTCATCTTCGCCGCCGACATCCTGACCAAGGGCCACACCGCCAACCGTCTGCTGGAT
GTCGTCGACGCCTTCACTCGCCACATCCGCGGTGGCTTGCCCATCACCACCGCCGCCTCCTGCGCGCTGTTCGGGGCCGT
GTCCGGCTCCACCCAGGCGACGGTGGTGGCGATGGGCGGTCCCATGCGCCCGAGGCTGCTGGCCAAGGGCTATAAAGACG
ATTTCACCCTGGGGCTGATCGTCAATGCCAGCGACATCGCGCTGCTGATCCCGCCGAGCATCGGCTTCATCGTCTACGGC
GTGGTGATGAAGACCTCGATCGGCGACCTGTTCCTCGCGGGGATCCTGCCCGGCCTGATGATCCTGGCCATGTTCGCCCT
GTACTGTTACATCTATTCGCGCATCAAGGGCATCGAGGCGGAGCCCCGGGCCTCCTGGCGCGAGCGCGCCCGCGCCATCC
GCCGGGTGATCCTGCCGATGGGTTTTCCGGTCCTGGTCGTGGGGGGCATATACGGCGGCTTTTTCAGCGCCGTCGAAGCC
TCGGCGGTCGCGGTGGCCTACGCGCTGCTGCTGGAGGTGGTGATCTATCGTCAGGTCTCGATCCGCGACCTCGGCAGCCT
CGCGCTGTCCACGGGGATGATCACCGCCGTGGTCTTCATCCTGGTCGCCATCGGTGCCGCCTTCTCCCAGACCCTGGGCA
CCGCCGGCGTGCCGGACAAGATCCTCGGCCCGGTCATCGACGGCATCGGCGACAACCAGTTCCTGGCACTGCTGCTGATC
GCCGCGGCCTTCTTCGTCGGCTGCATGTTCGTCGACCCGATCGTGGTCATCCTGATCCTGGTCCCGATCTTCAAGCCACT
GGTGGACGCCACTGGCCTGGATCCGGTTCACGTCGGCGTCATCGTCACGCTGCAAGCGGCCATCGGCTCGGCCACGCCAC
CCTTCGGCTGCGATATCTTCACCGCCATCGCCGTCTTCCGCCGCCCTTACATGGACGTGATTCGTGGTACGCCACCGTTC
ATCGTGATCCTGGCATTGGCGACGATCATCCTGATCATGTTCCCGCAGATATCGCTGCTGCTGCCGTCACTCGGCGGCGA
CTGA

Upstream 100 bases:

>100_bases
ACGAGCTGCCTCCGGAAGCGGACGAACACGATGACGCGCGCCGCGACACCTGATTCGCCCCTCCCACACACGACCGCCAT
CAACGCGAGGACGTAAAACA

Downstream 100 bases:

>100_bases
GCGGCCGACCGGCCTGGGGATACCAGGCCGGCCCCGCAGGGCATCCTTCCCGCCAACAGCGACCAGGCATGAAAAAACCC
CGGGAGCCGACGCTCCCGGG

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MLTWLAVIMLVLLLLGFPMMVPLAAGTLFMMFTGMTFFGPDQAVSWMINGIGSWVLAAVPMFIFAADILTKGHTANRLLD
VVDAFTRHIRGGLPITTAASCALFGAVSGSTQATVVAMGGPMRPRLLAKGYKDDFTLGLIVNASDIALLIPPSIGFIVYG
VVMKTSIGDLFLAGILPGLMILAMFALYCYIYSRIKGIEAEPRASWRERARAIRRVILPMGFPVLVVGGIYGGFFSAVEA
SAVAVAYALLLEVVIYRQVSIRDLGSLALSTGMITAVVFILVAIGAAFSQTLGTAGVPDKILGPVIDGIGDNQFLALLLI
AAAFFVGCMFVDPIVVILILVPIFKPLVDATGLDPVHVGVIVTLQAAIGSATPPFGCDIFTAIAVFRRPYMDVIRGTPPF
IVILALATIILIMFPQISLLLPSLGGD

Sequences:

>Translated_427_residues
MLTWLAVIMLVLLLLGFPMMVPLAAGTLFMMFTGMTFFGPDQAVSWMINGIGSWVLAAVPMFIFAADILTKGHTANRLLD
VVDAFTRHIRGGLPITTAASCALFGAVSGSTQATVVAMGGPMRPRLLAKGYKDDFTLGLIVNASDIALLIPPSIGFIVYG
VVMKTSIGDLFLAGILPGLMILAMFALYCYIYSRIKGIEAEPRASWRERARAIRRVILPMGFPVLVVGGIYGGFFSAVEA
SAVAVAYALLLEVVIYRQVSIRDLGSLALSTGMITAVVFILVAIGAAFSQTLGTAGVPDKILGPVIDGIGDNQFLALLLI
AAAFFVGCMFVDPIVVILILVPIFKPLVDATGLDPVHVGVIVTLQAAIGSATPPFGCDIFTAIAVFRRPYMDVIRGTPPF
IVILALATIILIMFPQISLLLPSLGGD
>Mature_427_residues
MLTWLAVIMLVLLLLGFPMMVPLAAGTLFMMFTGMTFFGPDQAVSWMINGIGSWVLAAVPMFIFAADILTKGHTANRLLD
VVDAFTRHIRGGLPITTAASCALFGAVSGSTQATVVAMGGPMRPRLLAKGYKDDFTLGLIVNASDIALLIPPSIGFIVYG
VVMKTSIGDLFLAGILPGLMILAMFALYCYIYSRIKGIEAEPRASWRERARAIRRVILPMGFPVLVVGGIYGGFFSAVEA
SAVAVAYALLLEVVIYRQVSIRDLGSLALSTGMITAVVFILVAIGAAFSQTLGTAGVPDKILGPVIDGIGDNQFLALLLI
AAAFFVGCMFVDPIVVILILVPIFKPLVDATGLDPVHVGVIVTLQAAIGSATPPFGCDIFTAIAVFRRPYMDVIRGTPPF
IVILALATIILIMFPQISLLLPSLGGD

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=421, Percent_Identity=29.6912114014252, Blast_Score=138, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45213; Mature: 45213

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTWLAVIMLVLLLLGFPMMVPLAAGTLFMMFTGMTFFGPDQAVSWMINGIGSWVLAAVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
MFIFAADILTKGHTANRLLDVVDAFTRHIRGGLPITTAASCALFGAVSGSTQATVVAMGG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEECC
PMRPRLLAKGYKDDFTLGLIVNASDIALLIPPSIGFIVYGVVMKTSIGDLFLAGILPGLM
CCCCHHHHCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAMFALYCYIYSRIKGIEAEPRASWRERARAIRRVILPMGFPVLVVGGIYGGFFSAVEA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SAVAVAYALLLEVVIYRQVSIRDLGSLALSTGMITAVVFILVAIGAAFSQTLGTAGVPDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ILGPVIDGIGDNQFLALLLIAAAFFVGCMFVDPIVVILILVPIFKPLVDATGLDPVHVGV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IVTLQAAIGSATPPFGCDIFTAIAVFRRPYMDVIRGTPPFIVILALATIILIMFPQISLL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LPSLGGD
HCCCCCC
>Mature Secondary Structure
MLTWLAVIMLVLLLLGFPMMVPLAAGTLFMMFTGMTFFGPDQAVSWMINGIGSWVLAAVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
MFIFAADILTKGHTANRLLDVVDAFTRHIRGGLPITTAASCALFGAVSGSTQATVVAMGG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEECC
PMRPRLLAKGYKDDFTLGLIVNASDIALLIPPSIGFIVYGVVMKTSIGDLFLAGILPGLM
CCCCHHHHCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAMFALYCYIYSRIKGIEAEPRASWRERARAIRRVILPMGFPVLVVGGIYGGFFSAVEA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SAVAVAYALLLEVVIYRQVSIRDLGSLALSTGMITAVVFILVAIGAAFSQTLGTAGVPDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ILGPVIDGIGDNQFLALLLIAAAFFVGCMFVDPIVVILILVPIFKPLVDATGLDPVHVGV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IVTLQAAIGSATPPFGCDIFTAIAVFRRPYMDVIRGTPPFIVILALATIILIMFPQISLL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LPSLGGD
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]