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The map label for this gene is hisQ [H]

Identifier: 92114900

GI number: 92114900

Start: 3114532

End: 3115248

Strand: Direct

Name: hisQ [H]

Synonym: Csal_2782

Alternate gene names: 92114900

Gene position: 3114532-3115248 (Clockwise)

Preceding gene: 92114899

Following gene: 92114901

Centisome position: 84.25

GC content: 62.06

Gene sequence:

>717_bases
ATGATCGACCTGCAGGGCTACGGCCCCCGGCTTCTCGAAGGTGCCCTGGTCACGGTGGAAGTCGCCGTGCTGTCGTTGTT
GCTGGCCCTGGTTCTGGGCCTGCTCACCGCCAGCGCCAAGCTGTCTCGCCACCGACTCTTGCACCGGATCGCCACGCTCT
ATACCACCCTCATCCGCGGGGTGCCCGACCTGGTATTGATGCTGCTGCTGTTCTTCGGCGGCCAGATGGGCGTCAATGCC
ATCACCGACTGGCTGTATTACCAGTTCGATGTGGATATCTTCATCAACATCAACGAATTCGTCGCCGGCGTCGTCACCAT
CGGCTTCATCTTCGGCGCCTACATGGGCGAGACGTTCCGGGGCGCCTTCCTCGCCGTCGACAGCGGCCAGCTCGAGGCCG
GACGCGCCTACGGCATGTCCAGCCGCCTCATCTTTCGGCGCATTCAGTTTCCGCAAATGATGCGTCACGCCCTTCCCGGC
CTGGGCAACAACTGGATGGTACTGCTCAAGACCACGGCCCTGGTCTCCGTCATCGGGCTTTCCGACATGGTGCGCATCGC
TGCCGAGGCGACCAAGGCCACCCATGAACCCTTCCTGTTCATGATCCCGGTCGCCGTCATCTATCTGCTGATCGCGAGCG
TGTCGGAGTGGGGCGTGGCGCGACTGCAAAAACGCTATAACGTCGGTTTCGGGGAGGCGGACGAATGGAACAACTGA

Upstream 100 bases:

>100_bases
GAAGCCGGGCCGCCGGAAGAAGTGCTGGGCAATCCCCAGTCGGAACGCCTCCAGCAATTCCTGGCACCCAAGCACTGATG
CCGCGACGGGAGAACATCGC

Downstream 100 bases:

>100_bases
ACGCCTGGTTCACCGAACTGCTCGCGGACAACGCCATCTTCACGGCCAACACCCTGGGGTATTACCTCGACGGGCTGGGC
AATACCGTGCGGCTGGTCTT

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MIDLQGYGPRLLEGALVTVEVAVLSLLLALVLGLLTASAKLSRHRLLHRIATLYTTLIRGVPDLVLMLLLFFGGQMGVNA
ITDWLYYQFDVDIFININEFVAGVVTIGFIFGAYMGETFRGAFLAVDSGQLEAGRAYGMSSRLIFRRIQFPQMMRHALPG
LGNNWMVLLKTTALVSVIGLSDMVRIAAEATKATHEPFLFMIPVAVIYLLIASVSEWGVARLQKRYNVGFGEADEWNN

Sequences:

>Translated_238_residues
MIDLQGYGPRLLEGALVTVEVAVLSLLLALVLGLLTASAKLSRHRLLHRIATLYTTLIRGVPDLVLMLLLFFGGQMGVNA
ITDWLYYQFDVDIFININEFVAGVVTIGFIFGAYMGETFRGAFLAVDSGQLEAGRAYGMSSRLIFRRIQFPQMMRHALPG
LGNNWMVLLKTTALVSVIGLSDMVRIAAEATKATHEPFLFMIPVAVIYLLIASVSEWGVARLQKRYNVGFGEADEWNN
>Mature_238_residues
MIDLQGYGPRLLEGALVTVEVAVLSLLLALVLGLLTASAKLSRHRLLHRIATLYTTLIRGVPDLVLMLLLFFGGQMGVNA
ITDWLYYQFDVDIFININEFVAGVVTIGFIFGAYMGETFRGAFLAVDSGQLEAGRAYGMSSRLIFRRIQFPQMMRHALPG
LGNNWMVLLKTTALVSVIGLSDMVRIAAEATKATHEPFLFMIPVAVIYLLIASVSEWGVARLQKRYNVGFGEADEWNN

Specific function: Part of the binding-protein-dependent transport system for histidine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4215

COG function: function code E; ABC-type arginine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788646, Length=232, Percent_Identity=51.7241379310345, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1787087, Length=224, Percent_Identity=35.7142857142857, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787030, Length=220, Percent_Identity=33.1818181818182, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788645, Length=215, Percent_Identity=30.6976744186047, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=28.5024154589372, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786874, Length=181, Percent_Identity=27.0718232044199, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786873, Length=217, Percent_Identity=24.8847926267281, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26333; Mature: 26333

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLQGYGPRLLEGALVTVEVAVLSLLLALVLGLLTASAKLSRHRLLHRIATLYTTLIRG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPDLVLMLLLFFGGQMGVNAITDWLYYQFDVDIFININEFVAGVVTIGFIFGAYMGETFR
CHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
GAFLAVDSGQLEAGRAYGMSSRLIFRRIQFPQMMRHALPGLGNNWMVLLKTTALVSVIGL
CEEEEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
SDMVRIAAEATKATHEPFLFMIPVAVIYLLIASVSEWGVARLQKRYNVGFGEADEWNN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIDLQGYGPRLLEGALVTVEVAVLSLLLALVLGLLTASAKLSRHRLLHRIATLYTTLIRG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPDLVLMLLLFFGGQMGVNAITDWLYYQFDVDIFININEFVAGVVTIGFIFGAYMGETFR
CHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
GAFLAVDSGQLEAGRAYGMSSRLIFRRIQFPQMMRHALPGLGNNWMVLLKTTALVSVIGL
CEEEEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
SDMVRIAAEATKATHEPFLFMIPVAVIYLLIASVSEWGVARLQKRYNVGFGEADEWNN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]