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The map label for this gene is degP [H]

Identifier: 92114333

GI number: 92114333

Start: 2485616

End: 2486854

Strand: Direct

Name: degP [H]

Synonym: Csal_2211

Alternate gene names: 92114333

Gene position: 2485616-2486854 (Clockwise)

Preceding gene: 92114331

Following gene: 92114343

Centisome position: 67.24

GC content: 65.7

Gene sequence:

>1239_bases
ATGCGCCGCTCACTGATGTCGCTCGTCTGGCCCACCATCAGTGGCATCCTGCTTGCCATCGTGCTGCTCAACGCCTTCCC
CCAGCTGCTTGGCGGACGCAACGCCGACGACACCGTGACGCCCGTCCCCGATACCAGCGCCGTGCGCGCCATTGCCGAAC
GCACCGATACCGCCGCCCGTGCCCCGGAAGTCGTCGAGGCCGCCCCGCTCGACCGGGCACAAGGACCGGCCAGCTATGCC
ACCGCGGTGGACAAGGCCGCCCCGGCCGTCGTCAATATCTACTCGTCGCGCATGGTCGATCCCAGCGAGCACCCCCTGAT
GTCCGACCCGTTCTTCGAGCAATTCTTCGGCAAGGACATGCCGCAACGTCAGCGCATGCTGTCCAGTCTGGGTTCCGGCG
TCATCGTGAGTCCCGAGGGCTACGTCCTCACGAACAACCACGTCATTCGCAACGCCGACCAGATCCAGGTCGCCCTGCGC
GACGGCCGCGAGACCCTCGCCGAGGTCGTCGGCACCGATCCCGAAAGCGACCTCGCGGTGCTCAAGATTCCCGTCGACAA
CCTGCCGGTCATCGAGCTCAGCGACTCGGAGCAGGTCGCCGTAGGGGACGTCAGCCTGGCCATCGGCAACCCCTTCGGCG
TGGGACAGACCGTGACCATGGGAATCATCAGCGCGACCGGACGCAACCATCTGGGGCTCAACGCCTACGAGGACTTCATT
CAAACCGATGCCGCCATCAACCCGGGCAACTCCGGTGGCGCCCTGGTTAATGCCGAAGGCGCTCTGGTGGGCATCAACAC
CGCGATCTTCTCCCGCTCGGGAGGCTCGCAAGGCATCGGTTTCGCGATTCCCGCCAACCTCGCCCATCAGGTACTCGATC
AGATCGTCGCGCATGGACGTGTCATTCGCGGCTGGCTGGGCATCGACGTCCAGGCGATGACTCCCGACCTTGCCACCTCT
TTCGGCCTGAAGACCCTCAAGGGCGTGGTCATCGCCAATGTCGTGCCCGGCGGCCCCGGCGAAAAGGCAGGCCTGCAGCC
CGGAGACGTGCTGATGTCCGTCAACGGCAAGATCATCGTCGACGCTCGCGAGGCGATGGCCGATATCGCGGAGATCTCGC
CCGGCACCTCGCTCCCCGTCACCATCGTGCGCGATGGCGAAAAGCGTGAGGTGACGCTGACGGTCGGCGAGCGCCCCCAG
GCAGCGCAGCGTCAACCAACCGCTCCCTCTTCTGAATGA

Upstream 100 bases:

>100_bases
GCGGCTCCAGACAGTTGGCGGATGCAATGTTACACTCGGCGCCATTGTAACGGCTGCCCCGAGGGGCGGCGACTGCCCGT
TCGCCGACAAGGAACCCGTC

Downstream 100 bases:

>100_bases
CGCGTCGACATCCCTGAGACGACACGGCCCCGCCGGCAATATATACCGACGGGGCCGTGAGGGGGCGGATGCGCAAGCCG
GGATGTCGGCCCGGCCCGAC

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRRSLMSLVWPTISGILLAIVLLNAFPQLLGGRNADDTVTPVPDTSAVRAIAERTDTAARAPEVVEAAPLDRAQGPASYA
TAVDKAAPAVVNIYSSRMVDPSEHPLMSDPFFEQFFGKDMPQRQRMLSSLGSGVIVSPEGYVLTNNHVIRNADQIQVALR
DGRETLAEVVGTDPESDLAVLKIPVDNLPVIELSDSEQVAVGDVSLAIGNPFGVGQTVTMGIISATGRNHLGLNAYEDFI
QTDAAINPGNSGGALVNAEGALVGINTAIFSRSGGSQGIGFAIPANLAHQVLDQIVAHGRVIRGWLGIDVQAMTPDLATS
FGLKTLKGVVIANVVPGGPGEKAGLQPGDVLMSVNGKIIVDAREAMADIAEISPGTSLPVTIVRDGEKREVTLTVGERPQ
AAQRQPTAPSSE

Sequences:

>Translated_412_residues
MRRSLMSLVWPTISGILLAIVLLNAFPQLLGGRNADDTVTPVPDTSAVRAIAERTDTAARAPEVVEAAPLDRAQGPASYA
TAVDKAAPAVVNIYSSRMVDPSEHPLMSDPFFEQFFGKDMPQRQRMLSSLGSGVIVSPEGYVLTNNHVIRNADQIQVALR
DGRETLAEVVGTDPESDLAVLKIPVDNLPVIELSDSEQVAVGDVSLAIGNPFGVGQTVTMGIISATGRNHLGLNAYEDFI
QTDAAINPGNSGGALVNAEGALVGINTAIFSRSGGSQGIGFAIPANLAHQVLDQIVAHGRVIRGWLGIDVQAMTPDLATS
FGLKTLKGVVIANVVPGGPGEKAGLQPGDVLMSVNGKIIVDAREAMADIAEISPGTSLPVTIVRDGEKREVTLTVGERPQ
AAQRQPTAPSSE
>Mature_412_residues
MRRSLMSLVWPTISGILLAIVLLNAFPQLLGGRNADDTVTPVPDTSAVRAIAERTDTAARAPEVVEAAPLDRAQGPASYA
TAVDKAAPAVVNIYSSRMVDPSEHPLMSDPFFEQFFGKDMPQRQRMLSSLGSGVIVSPEGYVLTNNHVIRNADQIQVALR
DGRETLAEVVGTDPESDLAVLKIPVDNLPVIELSDSEQVAVGDVSLAIGNPFGVGQTVTMGIISATGRNHLGLNAYEDFI
QTDAAINPGNSGGALVNAEGALVGINTAIFSRSGGSQGIGFAIPANLAHQVLDQIVAHGRVIRGWLGIDVQAMTPDLATS
FGLKTLKGVVIANVVPGGPGEKAGLQPGDVLMSVNGKIIVDAREAMADIAEISPGTSLPVTIVRDGEKREVTLTVGERPQ
AAQRQPTAPSSE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=333, Percent_Identity=34.5345345345345, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI22129776, Length=315, Percent_Identity=35.5555555555556, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI24308541, Length=395, Percent_Identity=30.8860759493671, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI7019477, Length=341, Percent_Identity=32.258064516129, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1789629, Length=336, Percent_Identity=44.047619047619, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1789630, Length=328, Percent_Identity=45.7317073170732, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI1786356, Length=372, Percent_Identity=41.3978494623656, Blast_Score=253, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24646839, Length=306, Percent_Identity=34.640522875817, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 43064; Mature: 43064

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSLMSLVWPTISGILLAIVLLNAFPQLLGGRNADDTVTPVPDTSAVRAIAERTDTAAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
APEVVEAAPLDRAQGPASYATAVDKAAPAVVNIYSSRMVDPSEHPLMSDPFFEQFFGKDM
CCHHHHHCCCCCCCCCHHHHHHHHHHCCHHEEHHHHHCCCCCCCCCCCCHHHHHHHCCCC
PQRQRMLSSLGSGVIVSPEGYVLTNNHVIRNADQIQVALRDGRETLAEVVGTDPESDLAV
HHHHHHHHHHCCCEEECCCCEEEECCCEEECCHHEEEEHHCCHHHHHHHHCCCCCCCEEE
LKIPVDNLPVIELSDSEQVAVGDVSLAIGNPFGVGQTVTMGIISATGRNHLGLNAYEDFI
EEECCCCCCEEEECCCCEEEEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHHH
QTDAAINPGNSGGALVNAEGALVGINTAIFSRSGGSQGIGFAIPANLAHQVLDQIVAHGR
HHCCCCCCCCCCCEEEECCCCEEEEEHHEEECCCCCCCCCEECCHHHHHHHHHHHHHCCC
VIRGWLGIDVQAMTPDLATSFGLKTLKGVVIANVVPGGPGEKAGLQPGDVLMSVNGKIIV
EEEEEECCEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEECCEEEE
DAREAMADIAEISPGTSLPVTIVRDGEKREVTLTVGERPQAAQRQPTAPSSE
ECHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCHHCCCCCCCCCC
>Mature Secondary Structure
MRRSLMSLVWPTISGILLAIVLLNAFPQLLGGRNADDTVTPVPDTSAVRAIAERTDTAAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
APEVVEAAPLDRAQGPASYATAVDKAAPAVVNIYSSRMVDPSEHPLMSDPFFEQFFGKDM
CCHHHHHCCCCCCCCCHHHHHHHHHHCCHHEEHHHHHCCCCCCCCCCCCHHHHHHHCCCC
PQRQRMLSSLGSGVIVSPEGYVLTNNHVIRNADQIQVALRDGRETLAEVVGTDPESDLAV
HHHHHHHHHHCCCEEECCCCEEEECCCEEECCHHEEEEHHCCHHHHHHHHCCCCCCCEEE
LKIPVDNLPVIELSDSEQVAVGDVSLAIGNPFGVGQTVTMGIISATGRNHLGLNAYEDFI
EEECCCCCCEEEECCCCEEEEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHHH
QTDAAINPGNSGGALVNAEGALVGINTAIFSRSGGSQGIGFAIPANLAHQVLDQIVAHGR
HHCCCCCCCCCCCEEEECCCCEEEEEHHEEECCCCCCCCCEECCHHHHHHHHHHHHHCCC
VIRGWLGIDVQAMTPDLATSFGLKTLKGVVIANVVPGGPGEKAGLQPGDVLMSVNGKIIV
EEEEEECCEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEECCEEEE
DAREAMADIAEISPGTSLPVTIVRDGEKREVTLTVGERPQAAQRQPTAPSSE
ECHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]