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The map label for this gene is lpxH

Identifier: 92114176

GI number: 92114176

Start: 2318281

End: 2319021

Strand: Direct

Name: lpxH

Synonym: Csal_2054

Alternate gene names: 92114176

Gene position: 2318281-2319021 (Clockwise)

Preceding gene: 92114175

Following gene: 161897780

Centisome position: 62.71

GC content: 64.78

Gene sequence:

>741_bases
ATGACCACCCTGCTGATTTCCGACTTGCACCTCCATACGGGCCAACCGGACATCACGCGCGGTTTCCTGGATTACCTGGA
ACGCGACGCACGTCACGCCGACACGCTCTACCTGCTTGGCGATATCTTCGAGGCCTGGATCGGCGACGATTATCTCGGTG
ACCTGGAACGCCAGGTCATCGAGGCACTGAGGCGTCTCAGCGATGCCGGCACCCAGCTCTATTTCATGCACGGCAATCGC
GACTTCCTGGTCGGCGAGGACTTCGCCGCCGCCGCCGGCGCCACCCTGCTCGACGATCCCTGTCTCGCGACGCTCGGCCG
TCAGACGGTGCTGCTGATGCACGGCGACAGTCTCTGCACCGGCGACGAGGAATACATGAAGTTTCGCGCCATGGCACGGG
ACCCCGAGTGGCAGGCCCAGATTCTTGCCTTGCCCATCGAGCAACGCCTGGAGCTGGCCAAGAGCCTGCGCATGCAATCC
TCGGATGCCAATACGCAAAAGGCGGATGCGATCATGGACGTCACGCCGGCGGAAGTCGAAGCGATCATGCGCGAGCATGG
CGTGAGCACCCTGATCCACGGCCACACCCACCGACCGGCGGTACACGAATTCACGCTCGACGGCCAGCCCGCCCAGCGTA
TCGTGCTGGGTGACTGGCGCCCCGGACGCGGCTGGGAGGTACGCGTCGAGGACGACGCCCCCCCACGGCTGCGTGAATTC
GCATTCCAGGCCCGCGCCTGA

Upstream 100 bases:

>100_bases
GCGCCTACGTCGAAGACTGATCGTTACGCGTCGCCGTGCCCGCGGGCACGGCATCGCCCTTCCGCTTCCTTCTCGCCACG
TTCACGAGGACGCCAGCACG

Downstream 100 bases:

>100_bases
TCAAACCCGGCGCCGACACGACTGGCGCCCTCTTCACGGTCTCAATGCTGGGGCTCGCCGAGCACACGGTCGAGTTGCGT
ACGCCAGCGCACCAGCATCG

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTTLLISDLHLHTGQPDITRGFLDYLERDARHADTLYLLGDIFEAWIGDDYLGDLERQVIEALRRLSDAGTQLYFMHGNR
DFLVGEDFAAAAGATLLDDPCLATLGRQTVLLMHGDSLCTGDEEYMKFRAMARDPEWQAQILALPIEQRLELAKSLRMQS
SDANTQKADAIMDVTPAEVEAIMREHGVSTLIHGHTHRPAVHEFTLDGQPAQRIVLGDWRPGRGWEVRVEDDAPPRLREF
AFQARA

Sequences:

>Translated_246_residues
MTTLLISDLHLHTGQPDITRGFLDYLERDARHADTLYLLGDIFEAWIGDDYLGDLERQVIEALRRLSDAGTQLYFMHGNR
DFLVGEDFAAAAGATLLDDPCLATLGRQTVLLMHGDSLCTGDEEYMKFRAMARDPEWQAQILALPIEQRLELAKSLRMQS
SDANTQKADAIMDVTPAEVEAIMREHGVSTLIHGHTHRPAVHEFTLDGQPAQRIVLGDWRPGRGWEVRVEDDAPPRLREF
AFQARA
>Mature_245_residues
TTLLISDLHLHTGQPDITRGFLDYLERDARHADTLYLLGDIFEAWIGDDYLGDLERQVIEALRRLSDAGTQLYFMHGNRD
FLVGEDFAAAAGATLLDDPCLATLGRQTVLLMHGDSLCTGDEEYMKFRAMARDPEWQAQILALPIEQRLELAKSLRMQSS
DANTQKADAIMDVTPAEVEAIMREHGVSTLIHGHTHRPAVHEFTLDGQPAQRIVLGDWRPGRGWEVRVEDDAPPRLREFA
FQARA

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family

Homologues:

Organism=Escherichia coli, GI1786735, Length=232, Percent_Identity=50, Blast_Score=222, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXH_CHRSD (Q1QVV3)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574104.1
- ProteinModelPortal:   Q1QVV3
- STRING:   Q1QVV3
- GeneID:   4026516
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2054
- NMPDR:   fig|290398.4.peg.1511
- eggNOG:   COG2908
- HOGENOM:   HBG288883
- OMA:   CHGDTLC
- BioCyc:   CSAL290398:CSAL_2054-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00575
- InterPro:   IPR004843
- InterPro:   IPR010138
- TIGRFAMs:   TIGR01854

Pfam domain/function: PF00149 Metallophos

EC number: 3.6.1.-

Molecular weight: Translated: 27706; Mature: 27574

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLISDLHLHTGQPDITRGFLDYLERDARHADTLYLLGDIFEAWIGDDYLGDLERQVI
CCEEEEEECEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EALRRLSDAGTQLYFMHGNRDFLVGEDFAAAAGATLLDDPCLATLGRQTVLLMHGDSLCT
HHHHHHHCCCCEEEEEECCCEEEECCCHHHHCCCHHHCCHHHHHCCCCEEEEEECCCCCC
GDEEYMKFRAMARDPEWQAQILALPIEQRLELAKSLRMQSSDANTQKADAIMDVTPAEVE
CCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHH
AIMREHGVSTLIHGHTHRPAVHEFTLDGQPAQRIVLGDWRPGRGWEVRVEDDAPPRLREF
HHHHHCCCCEEECCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCEEEECCCCCHHHHHH
AFQARA
HHHCCC
>Mature Secondary Structure 
TTLLISDLHLHTGQPDITRGFLDYLERDARHADTLYLLGDIFEAWIGDDYLGDLERQVI
CEEEEEECEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EALRRLSDAGTQLYFMHGNRDFLVGEDFAAAAGATLLDDPCLATLGRQTVLLMHGDSLCT
HHHHHHHCCCCEEEEEECCCEEEECCCHHHHCCCHHHCCHHHHHCCCCEEEEEECCCCCC
GDEEYMKFRAMARDPEWQAQILALPIEQRLELAKSLRMQSSDANTQKADAIMDVTPAEVE
CCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHH
AIMREHGVSTLIHGHTHRPAVHEFTLDGQPAQRIVLGDWRPGRGWEVRVEDDAPPRLREF
HHHHHCCCCEEECCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCEEEECCCCCHHHHHH
AFQARA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA