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The map label for this gene is mtnN

Identifier: 92114172

GI number: 92114172

Start: 2313587

End: 2314294

Strand: Direct

Name: mtnN

Synonym: Csal_2050

Alternate gene names: 92114172

Gene position: 2313587-2314294 (Clockwise)

Preceding gene: 92114171

Following gene: 92114175

Centisome position: 62.59

GC content: 63.84

Gene sequence:

>708_bases
ATGCGCAAGATTGCCATCATCGGTGCCATGGCCGAGGAAGTCGAACGCCTCGCCTCGCATCTGGAAAACCGCCAGACCCG
CCAGCATGCCGGCTCGACATTCCATTCGGGCCACCTGCATGGCGTCGAGGTCGTCATTCTGCAGTCGGGAATCGGCAAGG
TGAATGCCGCCGTCGGCACCACGCAACTGCTCGAAGCCTATCAGCCGGATGCGGTGATCAACACCGGCTCGGCAGGCGGC
TTCGGCGTCGACCTCGACGTCGGCGATGTGGTCATTTCCAGCGAGGTGCGTCATCACGATGTCGACGCGGTGGTGTTCGG
CTACGAATACGGCCAGGTCCCGCAGATGCCGGCCGCTTACGCACCCGACCCTCATCTGGTGAACGTCGCCCGCGAATGCA
TCGAGGGACTCGGCGAGCTGCGCGTCGCGGAAGGCCTCATCTGCACCGGTGACATCTTCATGGCCGACAAGGCCGCGGTC
GACCAGGCCCGCGAACGCTTTCCGAGCATGCTGGCCGCGGAAATGGAAGCGGCTGCCATCGCCCAGACGTGCCATCTGTA
CGGCTGCCCCTTCGTGGTCATTCGTGCGCTGTCCGATATCGCCGGCAAGGAGTCGGACCTCTCCTTCCAGGCCTTCATCG
AGAAAGCCGCAACGCACTCGGCGATGATGGTCGAAGCCATGGTCAAGCGGCTGGGCACTGCGAGCTAA

Upstream 100 bases:

>100_bases
ACAGTCTCGAAGGCGCTCAAGCCCTGGCACGCGACCTGCTGGCCAAGCGCAATGAATGGAACCAGGTGTTCGCCTGATCG
ATAGAGGGGTCACACTCCAA

Downstream 100 bases:

>100_bases
GAATGCACCTTCCCCGCGATGACGGGTGACAGCGACAAGGCAAAGAAAGGGGAGAAAAGGGTCTTTGCCAAGAACCCCAT
ACCGCCAACAGCCTTGAGAT

Product: methylthioadenosine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRKIAIIGAMAEEVERLASHLENRQTRQHAGSTFHSGHLHGVEVVILQSGIGKVNAAVGTTQLLEAYQPDAVINTGSAGG
FGVDLDVGDVVISSEVRHHDVDAVVFGYEYGQVPQMPAAYAPDPHLVNVARECIEGLGELRVAEGLICTGDIFMADKAAV
DQARERFPSMLAAEMEAAAIAQTCHLYGCPFVVIRALSDIAGKESDLSFQAFIEKAATHSAMMVEAMVKRLGTAS

Sequences:

>Translated_235_residues
MRKIAIIGAMAEEVERLASHLENRQTRQHAGSTFHSGHLHGVEVVILQSGIGKVNAAVGTTQLLEAYQPDAVINTGSAGG
FGVDLDVGDVVISSEVRHHDVDAVVFGYEYGQVPQMPAAYAPDPHLVNVARECIEGLGELRVAEGLICTGDIFMADKAAV
DQARERFPSMLAAEMEAAAIAQTCHLYGCPFVVIRALSDIAGKESDLSFQAFIEKAATHSAMMVEAMVKRLGTAS
>Mature_235_residues
MRKIAIIGAMAEEVERLASHLENRQTRQHAGSTFHSGHLHGVEVVILQSGIGKVNAAVGTTQLLEAYQPDAVINTGSAGG
FGVDLDVGDVVISSEVRHHDVDAVVFGYEYGQVPQMPAAYAPDPHLVNVARECIEGLGELRVAEGLICTGDIFMADKAAV
DQARERFPSMLAAEMEAAAIAQTCHLYGCPFVVIRALSDIAGKESDLSFQAFIEKAATHSAMMVEAMVKRLGTAS

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily

Homologues:

Organism=Escherichia coli, GI1786354, Length=229, Percent_Identity=49.7816593886463, Blast_Score=203, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNN_CHRSD (Q1QVV7)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574100.1
- ProteinModelPortal:   Q1QVV7
- SMR:   Q1QVV7
- STRING:   Q1QVV7
- GeneID:   4025950
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2050
- NMPDR:   fig|290398.4.peg.1649
- eggNOG:   COG0775
- HOGENOM:   HBG367723
- OMA:   AMEQEVT
- BioCyc:   CSAL290398:CSAL_2050-MONOMER
- HAMAP:   MF_01684
- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR01704

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =3.2.2.9

Molecular weight: Translated: 25017; Mature: 25017

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: ACT_SITE 13-13 BINDING 79-79 BINDING 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIAIIGAMAEEVERLASHLENRQTRQHAGSTFHSGHLHGVEVVILQSGIGKVNAAVGT
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHH
TQLLEAYQPDAVINTGSAGGFGVDLDVGDVVISSEVRHHDVDAVVFGYEYGQVPQMPAAY
HHHHHHHCCCCEEECCCCCCEEEECCCCCEEECCCHHHCCCCEEEEECCCCCCCCCCCCC
APDPHLVNVARECIEGLGELRVAEGLICTGDIFMADKAAVDQARERFPSMLAAEMEAAAI
CCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQTCHLYGCPFVVIRALSDIAGKESDLSFQAFIEKAATHSAMMVEAMVKRLGTAS
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKIAIIGAMAEEVERLASHLENRQTRQHAGSTFHSGHLHGVEVVILQSGIGKVNAAVGT
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHH
TQLLEAYQPDAVINTGSAGGFGVDLDVGDVVISSEVRHHDVDAVVFGYEYGQVPQMPAAY
HHHHHHHCCCCEEECCCCCCEEEECCCCCEEECCCHHHCCCCEEEEECCCCCCCCCCCCC
APDPHLVNVARECIEGLGELRVAEGLICTGDIFMADKAAVDQARERFPSMLAAEMEAAAI
CCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQTCHLYGCPFVVIRALSDIAGKESDLSFQAFIEKAATHSAMMVEAMVKRLGTAS
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA