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The map label for this gene is luxS

Identifier: 92114171

GI number: 92114171

Start: 2313096

End: 2313563

Strand: Direct

Name: luxS

Synonym: Csal_2049

Alternate gene names: 92114171

Gene position: 2313096-2313563 (Clockwise)

Preceding gene: 92114170

Following gene: 92114172

Centisome position: 62.57

GC content: 59.4

Gene sequence:

>468_bases
ATGAGCGACAAAGAAATGAACGTCGAGAGCTTCAACCTCGACCATACCAAGGTCAAGGCGCCCTATGTACGCCTGGCCGG
GATCAAGACCGGCGATCACGGCGATGCGATTCACAAGTACGATCTGCGTATCTGCCAGCCGAACAAGGCCCACATGGAAA
TGCCCGCCCTGCATTCCCTGGAACACCTGATGGCCGAATTGTCGCGCAACCACACCGACAAGATGCTCGACATCAGCCCC
ATGGGCTGCCAGACCGGCTTCTACGTCACGCTGATCAACCACGACGATTACGACGACGTGCTCGACCTCATCGACAAGAC
CCTCAACGACGTGCTCGTCGCCAAGGAAGTGCCGGCCTGCAACGAAATGCAGTGCGGCTGGGCCGCCAGCCACAGTCTCG
AAGGCGCTCAAGCCCTGGCACGCGACCTGCTGGCCAAGCGCAATGAATGGAACCAGGTGTTCGCCTGA

Upstream 100 bases:

>100_bases
AAAACACGCTGTTCGCCGCCGAACTGCACGACGGCATGCACGCCTAGCGTACAGGCGTTACAATGAACGGCTACATCCAG
TTCGAGAAAGGAGTGGAGAG

Downstream 100 bases:

>100_bases
TCGATAGAGGGGTCACACTCCAAATGCGCAAGATTGCCATCATCGGTGCCATGGCCGAGGAAGTCGAACGCCTCGCCTCG
CATCTGGAAAACCGCCAGAC

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSDKEMNVESFNLDHTKVKAPYVRLAGIKTGDHGDAIHKYDLRICQPNKAHMEMPALHSLEHLMAELSRNHTDKMLDISP
MGCQTGFYVTLINHDDYDDVLDLIDKTLNDVLVAKEVPACNEMQCGWAASHSLEGAQALARDLLAKRNEWNQVFA

Sequences:

>Translated_155_residues
MSDKEMNVESFNLDHTKVKAPYVRLAGIKTGDHGDAIHKYDLRICQPNKAHMEMPALHSLEHLMAELSRNHTDKMLDISP
MGCQTGFYVTLINHDDYDDVLDLIDKTLNDVLVAKEVPACNEMQCGWAASHSLEGAQALARDLLAKRNEWNQVFA
>Mature_154_residues
SDKEMNVESFNLDHTKVKAPYVRLAGIKTGDHGDAIHKYDLRICQPNKAHMEMPALHSLEHLMAELSRNHTDKMLDISPM
GCQTGFYVTLINHDDYDDVLDLIDKTLNDVLVAKEVPACNEMQCGWAASHSLEGAQALARDLLAKRNEWNQVFA

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=146, Percent_Identity=43.8356164383562, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_CHRSD (Q1QVV8)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574099.1
- ProteinModelPortal:   Q1QVV8
- SMR:   Q1QVV8
- STRING:   Q1QVV8
- GeneID:   4025949
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2049
- NMPDR:   fig|290398.4.peg.1507
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   DKYSCGN
- ProtClustDB:   PRK02260
- BioCyc:   CSAL290398:CSAL_2049-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17462; Mature: 17331

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKEMNVESFNLDHTKVKAPYVRLAGIKTGDHGDAIHKYDLRICQPNKAHMEMPALHSL
CCCCCCCCEEECCCCCEECCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHH
EHLMAELSRNHTDKMLDISPMGCQTGFYVTLINHDDYDDVLDLIDKTLNDVLVAKEVPAC
HHHHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
NEMQCGWAASHSLEGAQALARDLLAKRNEWNQVFA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure 
SDKEMNVESFNLDHTKVKAPYVRLAGIKTGDHGDAIHKYDLRICQPNKAHMEMPALHSL
CCCCCCCEEECCCCCEECCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHH
EHLMAELSRNHTDKMLDISPMGCQTGFYVTLINHDDYDDVLDLIDKTLNDVLVAKEVPAC
HHHHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
NEMQCGWAASHSLEGAQALARDLLAKRNEWNQVFA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA