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The map label for this gene is moeB [H]

Identifier: 92113656

GI number: 92113656

Start: 1744752

End: 1745531

Strand: Direct

Name: moeB [H]

Synonym: Csal_1532

Alternate gene names: 92113656

Gene position: 1744752-1745531 (Clockwise)

Preceding gene: 92113655

Following gene: 92113657

Centisome position: 47.2

GC content: 68.59

Gene sequence:

>780_bases
ATGACGGAAATGGACGATACCGCGCTGCTGCGCTATAGCCGCCAGATCATGCTCGAGCAGTTCGATGTGGCGGGGCAGCA
GCGCCTGCTGGCGGGGCATGCCTTGATCGTCGGCGCGGGAGGGCTGGGCTCGCCCGTGGCGCTGTATCTCGCCGCCGCCG
GGGTGGGGCGCCTGTCCATCGCCGACGACGATGTGGTGGAATTGTCCAATCTGCAGCGTCAAATCGCCCACGACGAGCGT
GATCTGGGCCGTGGCAAGGCCGAGTCGGCGGCGGTCTCGGCGCGGCGGCTCAATGCGGCCTGCCAGGTGGACGTCATTGC
CTCGCGGCTTGCGGGGGAGGCGCTGCAGCGTGCGGTGACGGAGGCGGACGTCGTGCTCGACTGCACCGACGGCTTCGCCA
GCCGCCATGCCATCAACCGTGCCTGTGTCGCCACGCGAACGCCGCTGGTATCCGGCGCGGCGATTCGCTTCTCGGGTCAG
CTGGCGGTCTTCGATGCGCGTGATGCGGCCTCGCCCTGTTATGCCTGCCTTTACGGCGAGGACGGTGACGACGAAGCGCT
GCGCTGCGCCGAAAACGGCGTGATCGCCCCTCTGGTGGGCATCATCGGCACCTTTCAGGCGCTCGAGGCGATCAAGCTTC
TCGCCGGCGTCGGTGAGTCACATCGCGGCCTGGCCACGTTCGATGGCCTGAGCGGAGAGTGGCGACGCTTCAATGTCGGT
CGCGACCCGGCGTGTCCCGTTTGCGGCCCTGGCCCGCACGGCGCGTCTGCCACGTCCTGA

Upstream 100 bases:

>100_bases
AGAAGTCAAGGAAGAGGTCTCGCTGCATGTGCCCGATATCGAGCGGCTCGATACATGACGGCGCCCCCGGGCGCTGCGCG
CGACTAAGGTGATGAATGTC

Downstream 100 bases:

>100_bases
TCCCTGAAAAGGAAGGTGCCGTCGCCGGATGGCAACGGCATGACGCCAATTTCGCAGACAATGTGAAAACGCTGTTCTAT
AACCCTTTCGGGCTCCCGCT

Product: UBA/THIF-type NAD/FAD binding fold protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTEMDDTALLRYSRQIMLEQFDVAGQQRLLAGHALIVGAGGLGSPVALYLAAAGVGRLSIADDDVVELSNLQRQIAHDER
DLGRGKAESAAVSARRLNAACQVDVIASRLAGEALQRAVTEADVVLDCTDGFASRHAINRACVATRTPLVSGAAIRFSGQ
LAVFDARDAASPCYACLYGEDGDDEALRCAENGVIAPLVGIIGTFQALEAIKLLAGVGESHRGLATFDGLSGEWRRFNVG
RDPACPVCGPGPHGASATS

Sequences:

>Translated_259_residues
MTEMDDTALLRYSRQIMLEQFDVAGQQRLLAGHALIVGAGGLGSPVALYLAAAGVGRLSIADDDVVELSNLQRQIAHDER
DLGRGKAESAAVSARRLNAACQVDVIASRLAGEALQRAVTEADVVLDCTDGFASRHAINRACVATRTPLVSGAAIRFSGQ
LAVFDARDAASPCYACLYGEDGDDEALRCAENGVIAPLVGIIGTFQALEAIKLLAGVGESHRGLATFDGLSGEWRRFNVG
RDPACPVCGPGPHGASATS
>Mature_258_residues
TEMDDTALLRYSRQIMLEQFDVAGQQRLLAGHALIVGAGGLGSPVALYLAAAGVGRLSIADDDVVELSNLQRQIAHDERD
LGRGKAESAAVSARRLNAACQVDVIASRLAGEALQRAVTEADVVLDCTDGFASRHAINRACVATRTPLVSGAAIRFSGQL
AVFDARDAASPCYACLYGEDGDDEALRCAENGVIAPLVGIIGTFQALEAIKLLAGVGESHRGLATFDGLSGEWRRFNVGR
DPACPVCGPGPHGASATS

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=228, Percent_Identity=46.0526315789474, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI4885649, Length=150, Percent_Identity=26, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1787048, Length=253, Percent_Identity=45.8498023715415, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI87082356, Length=246, Percent_Identity=49.1869918699187, Blast_Score=210, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI17540406, Length=245, Percent_Identity=42.8571428571429, Blast_Score=194, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI193203301, Length=153, Percent_Identity=24.8366013071895, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=246, Percent_Identity=36.5853658536585, Blast_Score=145, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24582879, Length=254, Percent_Identity=42.1259842519685, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24660640, Length=160, Percent_Identity=29.375, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26975; Mature: 26844

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEMDDTALLRYSRQIMLEQFDVAGQQRLLAGHALIVGAGGLGSPVALYLAAAGVGRLSI
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEE
ADDDVVELSNLQRQIAHDERDLGRGKAESAAVSARRLNAACQVDVIASRLAGEALQRAVT
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EADVVLDCTDGFASRHAINRACVATRTPLVSGAAIRFSGQLAVFDARDAASPCYACLYGE
HCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCCCEEEEEECC
DGDDEALRCAENGVIAPLVGIIGTFQALEAIKLLAGVGESHRGLATFDGLSGEWRRFNVG
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEECCC
RDPACPVCGPGPHGASATS
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEMDDTALLRYSRQIMLEQFDVAGQQRLLAGHALIVGAGGLGSPVALYLAAAGVGRLSI
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEE
ADDDVVELSNLQRQIAHDERDLGRGKAESAAVSARRLNAACQVDVIASRLAGEALQRAVT
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EADVVLDCTDGFASRHAINRACVATRTPLVSGAAIRFSGQLAVFDARDAASPCYACLYGE
HCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCCCEEEEEECC
DGDDEALRCAENGVIAPLVGIIGTFQALEAIKLLAGVGESHRGLATFDGLSGEWRRFNVG
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEECCC
RDPACPVCGPGPHGASATS
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]