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The map label for this gene is lrp [H]

Identifier: 92113655

GI number: 92113655

Start: 1744212

End: 1744709

Strand: Direct

Name: lrp [H]

Synonym: Csal_1531

Alternate gene names: 92113655

Gene position: 1744212-1744709 (Clockwise)

Preceding gene: 92113654

Following gene: 92113656

Centisome position: 47.18

GC content: 60.24

Gene sequence:

>498_bases
ATGAAAGCCAAGACCCGATCGCTCGATCGCATCGATCTCAACATTTTGCGCTGCCTGCAGGACAACGCCCGCATTTCCTA
CGTCGATCTGGCCTCCCGGGTGGGGCTGTCGACCACGCCCTGCCTGGAGCGTGTCAAGCGTCTGGAAAAGGCCGGCATCA
TCCGTGGCTACAAGGCACTGCTGGATCCCAAGGCCCTCAAGGCCAACCTGCTCGTGTTCGTCGAGATCAGCCTGGAAACG
CAGTCGCCGGCGGTATTCGACGAGTTCCGCCGGGCCGTGGCCAAGCTGCCGCAGATTCAAGAATGCCACCTGGTCTCCGG
CCAGTTCGATTACATCCTCAAGTGCCGCATTCCCGAGATGTCGGCCTATCGCCAGTTGCTGGGCGACGTGGTGCTGACGC
TGCCCGGTGTCAAGGAGTCCAAGAGCTACGTGGTGATGGAAGAAGTCAAGGAAGAGGTCTCGCTGCATGTGCCCGATATC
GAGCGGCTCGATACATGA

Upstream 100 bases:

>100_bases
GCCTCGCACTCGACGGTGCCGACGCCTGGCGGCCGCTTGATGCCGCCGGTGCCGTCGCGGGTATTTCCTTTGCCATTCAA
CGTCTCGGAACAATAATATA

Downstream 100 bases:

>100_bases
CGGCGCCCCCGGGCGCTGCGCGCGACTAAGGTGATGAATGTCATGACGGAAATGGACGATACCGCGCTGCTGCGCTATAG
CCGCCAGATCATGCTCGAGC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKAKTRSLDRIDLNILRCLQDNARISYVDLASRVGLSTTPCLERVKRLEKAGIIRGYKALLDPKALKANLLVFVEISLET
QSPAVFDEFRRAVAKLPQIQECHLVSGQFDYILKCRIPEMSAYRQLLGDVVLTLPGVKESKSYVVMEEVKEEVSLHVPDI
ERLDT

Sequences:

>Translated_165_residues
MKAKTRSLDRIDLNILRCLQDNARISYVDLASRVGLSTTPCLERVKRLEKAGIIRGYKALLDPKALKANLLVFVEISLET
QSPAVFDEFRRAVAKLPQIQECHLVSGQFDYILKCRIPEMSAYRQLLGDVVLTLPGVKESKSYVVMEEVKEEVSLHVPDI
ERLDT
>Mature_165_residues
MKAKTRSLDRIDLNILRCLQDNARISYVDLASRVGLSTTPCLERVKRLEKAGIIRGYKALLDPKALKANLLVFVEISLET
QSPAVFDEFRRAVAKLPQIQECHLVSGQFDYILKCRIPEMSAYRQLLGDVVLTLPGVKESKSYVVMEEVKEEVSLHVPDI
ERLDT

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=62.6666666666667, Blast_Score=196, Evalue=7e-52,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=34, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1790182, Length=144, Percent_Identity=25.6944444444444, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18701; Mature: 18701

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKTRSLDRIDLNILRCLQDNARISYVDLASRVGLSTTPCLERVKRLEKAGIIRGYKAL
CCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDPKALKANLLVFVEISLETQSPAVFDEFRRAVAKLPQIQECHLVSGQFDYILKCRIPEM
CCCHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHEEECCCCCEEEEECCCCH
SAYRQLLGDVVLTLPGVKESKSYVVMEEVKEEVSLHVPDIERLDT
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHHCCC
>Mature Secondary Structure
MKAKTRSLDRIDLNILRCLQDNARISYVDLASRVGLSTTPCLERVKRLEKAGIIRGYKAL
CCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDPKALKANLLVFVEISLETQSPAVFDEFRRAVAKLPQIQECHLVSGQFDYILKCRIPEM
CCCHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHEEECCCCCEEEEECCCCH
SAYRQLLGDVVLTLPGVKESKSYVVMEEVKEEVSLHVPDIERLDT
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]