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The map label for this gene is livK [C]

Identifier: 92113543

GI number: 92113543

Start: 1604636

End: 1605850

Strand: Direct

Name: livK [C]

Synonym: Csal_1418

Alternate gene names: 92113543

Gene position: 1604636-1605850 (Clockwise)

Preceding gene: 92113535

Following gene: 92113551

Centisome position: 43.41

GC content: 63.87

Gene sequence:

>1215_bases
ATGACCGTCAAGAAACCGCTTATCGGTGCTATTTCCGCGGTGGCCCTGGCCACCAGTATTTCCGCCCTGGCCGAACCGCT
CAAGATCGGTGTGCTGGTGCCGCTGACCGGCGACCTGCAAAGCTATGGCGAACCCGCGCTCAAGGCGGCGCAACTCGCGG
CCAAGGAGATCAATGCTGCCGGCGGCGTGCTCGGCGAAGACGTCGAGATCAGCAGTGGCGACACTCAGACCTCGCCGCAG
CCCGGCGTCGCCGCGGCCCAGAAGCTGGTCAACATCGAGGGCGTCAACGCGATCATGGGCGCGCTCTCCAGTGGGGTGAC
CATTCCCGTGGCGCAGAGCGTTGCCAAGGCCGAGCAGATACCGCAGGTCAGCAGCGCCTCGACTTCGCCGGTCATCACTT
CGCTGGATGACGACGACTTCCTGTTTCGTACCGTACCGTCTGACGCCTTCCAGGGCGTAGCGCTCTCCGAAGTGACCCAG
GAGAAGGGCTACGAAAACGTCAGCATCATCTATATCAACAACGATTACGGCAAAGGGTTGGCCGAGGCTTTCACCCAGGC
CTTCGAAAAGGCGGGGGGCACGGTGTCCGCCACGGTGGCCTACGAACAGGGCCAGGCGGCCTATCGCGGCGAACTGCAGC
AGGCGGCCAGCGACGATGCGGAGGCGCTGGTCCTGGTCGGCTATCCGGAGAACGGGCAGACCATCCTGCGTCAGGCGCTG
GAAGGCGGTTTCTTCCGAAACTTCGTGTTCACCGACGGCATGAAGGCCCCCGAGCTGGTCGACAACCTGGGGGCGCAATA
TCTCGAGGGCTCGGTGGGCACCGTGCCGCAGGCCCGCGACGACTCCCCGGGCGCCCAGCATTTCAGCAGCGCCTATGAGA
GCGAATACGACTCGCTGCCGCCCAAGCCCTATCTGGATACCGCCTACGACGCCTTCTATCTGCTGTCGCTGGCGGCTCAG
GCGGCGGGTTCCACCGACAGCGTGGCGATTCGCGACCAACTGCGCGCGGTGGCCAATCCGCCGGGCGAGCAGGTCGGTCC
GGGCGAGTTCGAGAAAGCCGTCAAGCTGCTCGAGGAAGGCAAGGAAATCGATTATGAAGGCGCGTCCGGTTCGGTCAACT
TCGACGACAACGGCGACGTGCCGGGGACCTTCGGCGAGTGGACGTTCAAGGATGGCGAAGTGGTGACCAATCGAATCTTC
GAACCCAAGATGTAA

Upstream 100 bases:

>100_bases
TCAGCGATCCGCTTATGCTGGACGTCGGGTTGATAGCAAAATGAAGGGTCATACCCGCCGATCAATCAACAATTAAGGTC
TGCACAAGGAGTCTTCTGCA

Downstream 100 bases:

>100_bases
TCGCTCGTCGGGCGGTCGGATGTCGTCTGGCCGCCGCGGCGAACGTTTCAGCGCTATTGCCATTCACGCAACGCCCGGCT
CAGGCCGGGCGTTGTCGTGA

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTVKKPLIGAISAVALATSISALAEPLKIGVLVPLTGDLQSYGEPALKAAQLAAKEINAAGGVLGEDVEISSGDTQTSPQ
PGVAAAQKLVNIEGVNAIMGALSSGVTIPVAQSVAKAEQIPQVSSASTSPVITSLDDDDFLFRTVPSDAFQGVALSEVTQ
EKGYENVSIIYINNDYGKGLAEAFTQAFEKAGGTVSATVAYEQGQAAYRGELQQAASDDAEALVLVGYPENGQTILRQAL
EGGFFRNFVFTDGMKAPELVDNLGAQYLEGSVGTVPQARDDSPGAQHFSSAYESEYDSLPPKPYLDTAYDAFYLLSLAAQ
AAGSTDSVAIRDQLRAVANPPGEQVGPGEFEKAVKLLEEGKEIDYEGASGSVNFDDNGDVPGTFGEWTFKDGEVVTNRIF
EPKM

Sequences:

>Translated_404_residues
MTVKKPLIGAISAVALATSISALAEPLKIGVLVPLTGDLQSYGEPALKAAQLAAKEINAAGGVLGEDVEISSGDTQTSPQ
PGVAAAQKLVNIEGVNAIMGALSSGVTIPVAQSVAKAEQIPQVSSASTSPVITSLDDDDFLFRTVPSDAFQGVALSEVTQ
EKGYENVSIIYINNDYGKGLAEAFTQAFEKAGGTVSATVAYEQGQAAYRGELQQAASDDAEALVLVGYPENGQTILRQAL
EGGFFRNFVFTDGMKAPELVDNLGAQYLEGSVGTVPQARDDSPGAQHFSSAYESEYDSLPPKPYLDTAYDAFYLLSLAAQ
AAGSTDSVAIRDQLRAVANPPGEQVGPGEFEKAVKLLEEGKEIDYEGASGSVNFDDNGDVPGTFGEWTFKDGEVVTNRIF
EPKM
>Mature_403_residues
TVKKPLIGAISAVALATSISALAEPLKIGVLVPLTGDLQSYGEPALKAAQLAAKEINAAGGVLGEDVEISSGDTQTSPQP
GVAAAQKLVNIEGVNAIMGALSSGVTIPVAQSVAKAEQIPQVSSASTSPVITSLDDDDFLFRTVPSDAFQGVALSEVTQE
KGYENVSIIYINNDYGKGLAEAFTQAFEKAGGTVSATVAYEQGQAAYRGELQQAASDDAEALVLVGYPENGQTILRQALE
GGFFRNFVFTDGMKAPELVDNLGAQYLEGSVGTVPQARDDSPGAQHFSSAYESEYDSLPPKPYLDTAYDAFYLLSLAAQA
AGSTDSVAIRDQLRAVANPPGEQVGPGEFEKAVKLLEEGKEIDYEGASGSVNFDDNGDVPGTFGEWTFKDGEVVTNRIFE
PKM

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Homo sapiens, GI4504147, Length=109, Percent_Identity=37.6146788990826, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI110611176, Length=105, Percent_Identity=38.0952380952381, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI32528268, Length=109, Percent_Identity=37.6146788990826, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI187960069, Length=131, Percent_Identity=31.2977099236641, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI187960067, Length=131, Percent_Identity=31.2977099236641, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789867, Length=341, Percent_Identity=27.5659824046921, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI48994941, Length=326, Percent_Identity=29.4478527607362, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221330057, Length=344, Percent_Identity=24.4186046511628, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330059, Length=339, Percent_Identity=23.8938053097345, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330055, Length=339, Percent_Identity=23.8938053097345, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 42281; Mature: 42150

Theoretical pI: Translated: 3.96; Mature: 3.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKKPLIGAISAVALATSISALAEPLKIGVLVPLTGDLQSYGEPALKAAQLAAKEINAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHCCCHHHHHHHHHHHHHHHC
GGVLGEDVEISSGDTQTSPQPGVAAAQKLVNIEGVNAIMGALSSGVTIPVAQSVAKAEQI
CCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEHHHHHHHHHHHC
PQVSSASTSPVITSLDDDDFLFRTVPSDAFQGVALSEVTQEKGYENVSIIYINNDYGKGL
CCCCCCCCCCEEEECCCCCCEEEECCCHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCHH
AEAFTQAFEKAGGTVSATVAYEQGQAAYRGELQQAASDDAEALVLVGYPENGQTILRQAL
HHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHH
EGGFFRNFVFTDGMKAPELVDNLGAQYLEGSVGTVPQARDDSPGAQHFSSAYESEYDSLP
CCCCEEHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PKPYLDTAYDAFYLLSLAAQAAGSTDSVAIRDQLRAVANPPGEQVGPGEFEKAVKLLEEG
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
KEIDYEGASGSVNFDDNGDVPGTFGEWTFKDGEVVTNRIFEPKM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TVKKPLIGAISAVALATSISALAEPLKIGVLVPLTGDLQSYGEPALKAAQLAAKEINAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHCCCHHHHHHHHHHHHHHHC
GGVLGEDVEISSGDTQTSPQPGVAAAQKLVNIEGVNAIMGALSSGVTIPVAQSVAKAEQI
CCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEHHHHHHHHHHHC
PQVSSASTSPVITSLDDDDFLFRTVPSDAFQGVALSEVTQEKGYENVSIIYINNDYGKGL
CCCCCCCCCCEEEECCCCCCEEEECCCHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCHH
AEAFTQAFEKAGGTVSATVAYEQGQAAYRGELQQAASDDAEALVLVGYPENGQTILRQAL
HHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHH
EGGFFRNFVFTDGMKAPELVDNLGAQYLEGSVGTVPQARDDSPGAQHFSSAYESEYDSLP
CCCCEEHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PKPYLDTAYDAFYLLSLAAQAAGSTDSVAIRDQLRAVANPPGEQVGPGEFEKAVKLLEEG
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
KEIDYEGASGSVNFDDNGDVPGTFGEWTFKDGEVVTNRIFEPKM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]