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The map label for this gene is aroK

Identifier: 92112746

GI number: 92112746

Start: 682515

End: 683057

Strand: Direct

Name: aroK

Synonym: Csal_0613

Alternate gene names: 92112746

Gene position: 682515-683057 (Clockwise)

Preceding gene: 92112745

Following gene: 92112747

Centisome position: 18.46

GC content: 66.48

Gene sequence:

>543_bases
ATGCAGGGGTTGCCCACGATCATCCTCGTCGGCCCCATGGGCGCGGGGAAAAGCACGATTGGCCGTTTGCTGGCGGCCGA
ACTCCAGCGCGAGTTCTTCGATAGCGATCACGAGATCGAAGCGCGCTGCGGGGCGAATATCGCCTGGATCTTCGATGTCG
AAGGCGAGGCCGGTTTTCGCGATCGCGAAACGGCCATGCTGCGCGAGCTGGCGAGCCTCGATGCCGTCGTGCTGGCCACC
GGGGGCGGTGCGGTGATGCGTGAAGACAATCGCCAGGCGCTGCGCGAGCGCGGCACGGTGGTGTACCTGGCGACCTCCGT
CGAGCAGCAGATTCGGCGCACCGCGCGCGATCGCAACCGGCCGCTGCTCCGTCAGGGCAATCCCGAGCAGGTGTTGCGCG
ACCTGTTCGCCAAGCGCGATCCGCTTTACCGGGCCACCGCCGATCTGGTGGTGCGGACCGATCGACGCGGTCCGCGGGCG
GTGGTCAACGAGATCATTCGCCGCACCAAGCGTTTGTCCGATCCACTCGACCTCAAGGCTTGA

Upstream 100 bases:

>100_bases
TCGGTTCGCTGTTCCGCTATACCCAGGAATCCAACGAAAAGGTAGAATTGCTGATCTTCATAACACCCACGATCATCGGA
GACGGACAGGCGAATCGCTG

Downstream 100 bases:

>100_bases
TCATGACCGCTTCGACCGCCTCGCCGTCCCAATGCCTGCACGTCGAACTCGACGCGCGGCGCTACCCCATCCATGTGGGG
CCTGGTCTGCTCGACGACCC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MQGLPTIILVGPMGAGKSTIGRLLAAELQREFFDSDHEIEARCGANIAWIFDVEGEAGFRDRETAMLRELASLDAVVLAT
GGGAVMREDNRQALRERGTVVYLATSVEQQIRRTARDRNRPLLRQGNPEQVLRDLFAKRDPLYRATADLVVRTDRRGPRA
VVNEIIRRTKRLSDPLDLKA

Sequences:

>Translated_180_residues
MQGLPTIILVGPMGAGKSTIGRLLAAELQREFFDSDHEIEARCGANIAWIFDVEGEAGFRDRETAMLRELASLDAVVLAT
GGGAVMREDNRQALRERGTVVYLATSVEQQIRRTARDRNRPLLRQGNPEQVLRDLFAKRDPLYRATADLVVRTDRRGPRA
VVNEIIRRTKRLSDPLDLKA
>Mature_180_residues
MQGLPTIILVGPMGAGKSTIGRLLAAELQREFFDSDHEIEARCGANIAWIFDVEGEAGFRDRETAMLRELASLDAVVLAT
GGGAVMREDNRQALRERGTVVYLATSVEQQIRRTARDRNRPLLRQGNPEQVLRDLFAKRDPLYRATADLVVRTDRRGPRA
VVNEIIRRTKRLSDPLDLKA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=163, Percent_Identity=53.3742331288344, Blast_Score=180, Evalue=6e-47,
Organism=Escherichia coli, GI1786587, Length=162, Percent_Identity=35.1851851851852, Blast_Score=97, Evalue=8e-22,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_CHRSD (Q1QZY3)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572674.1
- ProteinModelPortal:   Q1QZY3
- SMR:   Q1QZY3
- STRING:   Q1QZY3
- GeneID:   4029082
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0613
- NMPDR:   fig|290398.4.peg.383
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- ProtClustDB:   PRK00131
- BioCyc:   CSAL290398:CSAL_0613-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR003593
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100
- SMART:   SM00382

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20164; Mature: 20164

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 36-36 BINDING 60-60 BINDING 82-82 BINDING 120-120 BINDING 139-139

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLPTIILVGPMGAGKSTIGRLLAAELQREFFDSDHEIEARCGANIAWIFDVEGEAGFR
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEECCCCCCC
DRETAMLRELASLDAVVLATGGGAVMREDNRQALRERGTVVYLATSVEQQIRRTARDRNR
HHHHHHHHHHHHCCEEEEEECCCCEEECCHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCC
PLLRQGNPEQVLRDLFAKRDPLYRATADLVVRTDRRGPRAVVNEIIRRTKRLSDPLDLKA
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQGLPTIILVGPMGAGKSTIGRLLAAELQREFFDSDHEIEARCGANIAWIFDVEGEAGFR
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEECCCCCCC
DRETAMLRELASLDAVVLATGGGAVMREDNRQALRERGTVVYLATSVEQQIRRTARDRNR
HHHHHHHHHHHHCCEEEEEECCCCEEECCHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCC
PLLRQGNPEQVLRDLFAKRDPLYRATADLVVRTDRRGPRAVVNEIIRRTKRLSDPLDLKA
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA