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The map label for this gene is aroB [H]

Identifier: 92112747

GI number: 92112747

Start: 683060

End: 684172

Strand: Direct

Name: aroB [H]

Synonym: Csal_0614

Alternate gene names: 92112747

Gene position: 683060-684172 (Clockwise)

Preceding gene: 92112746

Following gene: 92112748

Centisome position: 18.48

GC content: 67.21

Gene sequence:

>1113_bases
ATGACCGCTTCGACCGCCTCGCCGTCCCAATGCCTGCACGTCGAACTCGACGCGCGGCGCTACCCCATCCATGTGGGGCC
TGGTCTGCTCGACGACCCGGCCATGCTGGTGCCATATCTTGCCGGCCGGCAGGTGATGATCGTCACCAACGAAACGGTGG
CGCCGCGCTATCTCGAACGTCTCAAGCGAGCGCTGAGCGGTGATGATCGCGACGTGCGCGAGATCGTGCTGCCCGATGGC
GAGCACACCAAGACGCTGGCCAGCGTGGAGCGTATCTGGGATGCGCTGCTCGCCGCCGGCTTCAACCGTCGCTGTACCCT
GGTGGCGCTCGGCGGCGGCGTGATCGGCGACATGGCAGGCTTCGCCGCGGCGTGCTATCAGCGCGGCGTGGCTTTCGTGC
AGGTTCCCACCACGCTATTGTCGCAGGTGGATTCTTCGGTGGGCGGCAAGACCGGCGTCAATCATCCGCGCGGCAAGAAC
ATGATCGGTGCCTTCTGGCAGCCCCGCGCGGTGGTGATCGATACCCAGACGCTCACCACGCTGCCGTCCCGCGAGCTGTC
CGCGGGGCTCGCCGAGGTGATCAAGTACGGCCTGATCCACGATATCGAGTTCCTGGCCTGGCTGGAATCGCGCATGACGG
CGCTGCGGGCGCTCGACGCCGAAGCGCTCACCGAGGCGATTCTGCGCAGCTGCGCGATCAAGGCGGAGATCGTCGCCGCC
GACGAAACCGAGCAGGGGCAGCGGGCGTTGCTCAACCTCGGGCATACCTTCGGGCACGCCATCGAGGCGCACCAGGGCTA
TGGCAACTGGCTGCATGGCGAAGCCGTGGGGGCGGGGATGGCGATGGCCGCCGAACTCTCGCGGCGTCTCGGTTGGCTAG
ACGACGCCGAGGTGGCGCGCGTCGAAGCGCTCATCGTCCACGCCGGTCTGCCGGTGACGGCCCCCGCCGCCATGAGCGGT
GACGACTTTCTTGCCACCATGCGGCTGGACAAGAAAAACATCGACGCACGCTTGCGTCTGGTGTTGCTGTCGCGACTCGG
CGAGGCTTGCATCCACGACGCGACGCCGCCCGATATGCTCGATGCGCTGCTCGCGGACTTCCCCCGCCACTGA

Upstream 100 bases:

>100_bases
TGGTGGTGCGGACCGATCGACGCGGTCCGCGGGCGGTGGTCAACGAGATCATTCGCCGCACCAAGCGTTTGTCCGATCCA
CTCGACCTCAAGGCTTGATC

Downstream 100 bases:

>100_bases
CGACGCTCGGTCTCGCCCGGCCCCCCTGCACGACGCCTGCCGCTCCGGCAGGCGTTTTTGGTTGTGTCACGGTCCCCGCA
TGCGGATTTGTGCGCTGACG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTASTASPSQCLHVELDARRYPIHVGPGLLDDPAMLVPYLAGRQVMIVTNETVAPRYLERLKRALSGDDRDVREIVLPDG
EHTKTLASVERIWDALLAAGFNRRCTLVALGGGVIGDMAGFAAACYQRGVAFVQVPTTLLSQVDSSVGGKTGVNHPRGKN
MIGAFWQPRAVVIDTQTLTTLPSRELSAGLAEVIKYGLIHDIEFLAWLESRMTALRALDAEALTEAILRSCAIKAEIVAA
DETEQGQRALLNLGHTFGHAIEAHQGYGNWLHGEAVGAGMAMAAELSRRLGWLDDAEVARVEALIVHAGLPVTAPAAMSG
DDFLATMRLDKKNIDARLRLVLLSRLGEACIHDATPPDMLDALLADFPRH

Sequences:

>Translated_370_residues
MTASTASPSQCLHVELDARRYPIHVGPGLLDDPAMLVPYLAGRQVMIVTNETVAPRYLERLKRALSGDDRDVREIVLPDG
EHTKTLASVERIWDALLAAGFNRRCTLVALGGGVIGDMAGFAAACYQRGVAFVQVPTTLLSQVDSSVGGKTGVNHPRGKN
MIGAFWQPRAVVIDTQTLTTLPSRELSAGLAEVIKYGLIHDIEFLAWLESRMTALRALDAEALTEAILRSCAIKAEIVAA
DETEQGQRALLNLGHTFGHAIEAHQGYGNWLHGEAVGAGMAMAAELSRRLGWLDDAEVARVEALIVHAGLPVTAPAAMSG
DDFLATMRLDKKNIDARLRLVLLSRLGEACIHDATPPDMLDALLADFPRH
>Mature_369_residues
TASTASPSQCLHVELDARRYPIHVGPGLLDDPAMLVPYLAGRQVMIVTNETVAPRYLERLKRALSGDDRDVREIVLPDGE
HTKTLASVERIWDALLAAGFNRRCTLVALGGGVIGDMAGFAAACYQRGVAFVQVPTTLLSQVDSSVGGKTGVNHPRGKNM
IGAFWQPRAVVIDTQTLTTLPSRELSAGLAEVIKYGLIHDIEFLAWLESRMTALRALDAEALTEAILRSCAIKAEIVAAD
ETEQGQRALLNLGHTFGHAIEAHQGYGNWLHGEAVGAGMAMAAELSRRLGWLDDAEVARVEALIVHAGLPVTAPAAMSGD
DFLATMRLDKKNIDARLRLVLLSRLGEACIHDATPPDMLDALLADFPRH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=353, Percent_Identity=55.2407932011331, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6320332, Length=346, Percent_Identity=38.728323699422, Blast_Score=209, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39873; Mature: 39742

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASTASPSQCLHVELDARRYPIHVGPGLLDDPAMLVPYLAGRQVMIVTNETVAPRYLER
CCCCCCCCCCEEEEEECCCCCCEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHH
LKRALSGDDRDVREIVLPDGEHTKTLASVERIWDALLAAGFNRRCTLVALGGGVIGDMAG
HHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
FAAACYQRGVAFVQVPTTLLSQVDSSVGGKTGVNHPRGKNMIGAFWQPRAVVIDTQTLTT
HHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHC
LPSRELSAGLAEVIKYGLIHDIEFLAWLESRMTALRALDAEALTEAILRSCAIKAEIVAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEC
DETEQGQRALLNLGHTFGHAIEAHQGYGNWLHGEAVGAGMAMAAELSRRLGWLDDAEVAR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
VEALIVHAGLPVTAPAAMSGDDFLATMRLDKKNIDARLRLVLLSRLGEACIHDATPPDML
HHHHEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
DALLADFPRH
HHHHHHCCCC
>Mature Secondary Structure 
TASTASPSQCLHVELDARRYPIHVGPGLLDDPAMLVPYLAGRQVMIVTNETVAPRYLER
CCCCCCCCCEEEEEECCCCCCEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHH
LKRALSGDDRDVREIVLPDGEHTKTLASVERIWDALLAAGFNRRCTLVALGGGVIGDMAG
HHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
FAAACYQRGVAFVQVPTTLLSQVDSSVGGKTGVNHPRGKNMIGAFWQPRAVVIDTQTLTT
HHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHC
LPSRELSAGLAEVIKYGLIHDIEFLAWLESRMTALRALDAEALTEAILRSCAIKAEIVAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEC
DETEQGQRALLNLGHTFGHAIEAHQGYGNWLHGEAVGAGMAMAAELSRRLGWLDDAEVAR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
VEALIVHAGLPVTAPAAMSGDDFLATMRLDKKNIDARLRLVLLSRLGEACIHDATPPDML
HHHHEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
DALLADFPRH
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA