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The map label for this gene is pilQ [H]

Identifier: 92112745

GI number: 92112745

Start: 680509

End: 682515

Strand: Direct

Name: pilQ [H]

Synonym: Csal_0612

Alternate gene names: 92112745

Gene position: 680509-682515 (Clockwise)

Preceding gene: 92112744

Following gene: 92112746

Centisome position: 18.41

GC content: 64.52

Gene sequence:

>2007_bases
ATGATGATGCGAACGCTGCGAGGCTGGCTGAGCGGCTGGCTCTGGCTGGTTGGGGTGATCGTCTGCGCCCAGGGGCAGGC
GGCGACGCTGACGTCGCTGGACATCGCCCAGCGCGAGGATGGCGGCATCGATGCCATGCTCGGTTTCGACGGGCCGGCGC
CTGAGGCGCACAGTTACCGCGGCGACGCGCCGGCGCAGATGATCGTCGACCTGCCGGATACGGCCAGTGGGCTCGAGCAA
CGCACGGTCGAGGTCGGGCAGGGCGGGCTGCGCGACATCAGCGTCGTCGACGCTGCCGAACGCACGCGTCTGGTCTTCGG
ACTGACGTCGCCCCAGGCATATTCGGTCCAGCGCCAGGGCGATCGTCTGAGGGTGCGATTGGGCAGCGAGGCGATCCCGG
ATGGCGTGACGTCCATCCGCGATCTCGATTTTCGCCGAGGCAATGCCGGCGGCGGGCGGCTGGTGGTGACCCTCGATGCG
CCCGGGGTGTCTCCGGAAACCTCGGTCGACGGCAATACCCTGACACTGACGTTGCCCGGCACGCGCTTGCCCGACGCATT
GGATCGCATTCTCGATGTCAGCGACTTCGCCACACCGGTGTCGCGTATCGTGCCGAATCGCCAGGACGATGCCGTGACCC
TGACGCTGGAGAATCGCGAGCCCTTTCAGCATCTGGTGACGCAGCGCGGTGATCGCCTGATCGTCGACGTGCAACCCCGC
AACGAGCAGACCAGCGATGCCCGGGACGCCTCGCCGACCTATACCGGCGAGCCGATCAGCCTCAATTTCCAGAATATCCA
GGTGCGTGAGGTGCTGTCGGTCCTGTCCGATTTCAGCGGGCTCAACATCGTGGCCAGCGATAGCGTACAGGGCAGCGTGA
CACTCAATCTCCAGCAGGTGCCCTGGGATCAGGCATTGGCATTGATCCTGCAGAGTCACGGGTTGGCCAGCCGCCGCAAC
GGCGACGTGATCGTGGTGGCGCCCGTCGATGAACTGGCGCAGATGGAACGTCAGACTCTGGAGAACCGCGCTCAATCCGA
GCAGTTGGCCCCCCTGGTCACCGACTACGTGCAGGTGCGCTATGCCAAGGCCACCGATCTGGCGGCGATGCTGCGCGGCA
GCGAAGGCTTCGGTCTGCTTTCCGAGCGCGGGCGCGTCACGGTCGATGAGCGCACCAATACCCTGCTGGTGCGTGATACC
CGCGAGCAACTGGCCAGCATCCGCGGCATGCTCGAGCGGCTCGACGTGCCGGTGCGCCAGGTGCAGATCGAGGCGCGCAT
CGTCATCGCGCGCGACACGGCGTCCCGGGAACTGGGCGTCAACTGGGGCATCTCGCAGCGCCAGGGCGTCACCTTCGATG
ACGACGGCGTGGGCAGCGTGGTGGACCGCAACCCCAGTGGCGCCAACCGCGGCTCCGCCGGCTTGTCCGTGGACCTGGGC
GACAGCGACGGCAGCGGCTCCACCTTCAGCTTCGGTTACCTTTCCGGCGATGTCCTGCTCGACCTGGAATTGCGCGCCCT
GGAAAGCGAGGGCAAGAGTCAGACCATCTCTCAGCCCAAGGTGATCACCGCCAACCAGAAGACGGCGGTCATCAAGCAGG
GACAGGAGATCCCCTACCAGGAGTCGACCTCGTCCGGTGCCACCAACGTGGAATTCAAGGAAGCCGTGCTGTCGCTGGAG
GCCACACCGCAGATCACGCCCGACGGCAGTATCGTCATGGATCTGTTGATCAACAACGATACCGTCGCCGACAACAGCTA
TGATGGTGCACCTGCGATCGATACCAATTCCATCGAGACCCAGGTGCTCGTGGACGATGGTGCCACGGTGGTGCTGGGCG
GCATCCTGACGTCCGAACAGCTGCGCAACCTCTACAAGACCCCGTTCCTCGGGGACTTGCCGTTGATCGGTTCGCTGTTC
CGCTATACCCAGGAATCCAACGAAAAGGTAGAATTGCTGATCTTCATAACACCCACGATCATCGGAGACGGACAGGCGAA
TCGCTGA

Upstream 100 bases:

>100_bases
GATTCATCCCAAGCCGCCGAATAGACGCGCCGGGCAAGCACCACGTACAGGCATGTTGTCGGATAACGCCAAGAGCGGAT
GGGAACAGGCAGGGAGATCC

Downstream 100 bases:

>100_bases
TGCAGGGGTTGCCCACGATCATCCTCGTCGGCCCCATGGGCGCGGGGAAAAGCACGATTGGCCGTTTGCTGGCGGCCGAA
CTCCAGCGCGAGTTCTTCGA

Product: type II and III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MMMRTLRGWLSGWLWLVGVIVCAQGQAATLTSLDIAQREDGGIDAMLGFDGPAPEAHSYRGDAPAQMIVDLPDTASGLEQ
RTVEVGQGGLRDISVVDAAERTRLVFGLTSPQAYSVQRQGDRLRVRLGSEAIPDGVTSIRDLDFRRGNAGGGRLVVTLDA
PGVSPETSVDGNTLTLTLPGTRLPDALDRILDVSDFATPVSRIVPNRQDDAVTLTLENREPFQHLVTQRGDRLIVDVQPR
NEQTSDARDASPTYTGEPISLNFQNIQVREVLSVLSDFSGLNIVASDSVQGSVTLNLQQVPWDQALALILQSHGLASRRN
GDVIVVAPVDELAQMERQTLENRAQSEQLAPLVTDYVQVRYAKATDLAAMLRGSEGFGLLSERGRVTVDERTNTLLVRDT
REQLASIRGMLERLDVPVRQVQIEARIVIARDTASRELGVNWGISQRQGVTFDDDGVGSVVDRNPSGANRGSAGLSVDLG
DSDGSGSTFSFGYLSGDVLLDLELRALESEGKSQTISQPKVITANQKTAVIKQGQEIPYQESTSSGATNVEFKEAVLSLE
ATPQITPDGSIVMDLLINNDTVADNSYDGAPAIDTNSIETQVLVDDGATVVLGGILTSEQLRNLYKTPFLGDLPLIGSLF
RYTQESNEKVELLIFITPTIIGDGQANR

Sequences:

>Translated_668_residues
MMMRTLRGWLSGWLWLVGVIVCAQGQAATLTSLDIAQREDGGIDAMLGFDGPAPEAHSYRGDAPAQMIVDLPDTASGLEQ
RTVEVGQGGLRDISVVDAAERTRLVFGLTSPQAYSVQRQGDRLRVRLGSEAIPDGVTSIRDLDFRRGNAGGGRLVVTLDA
PGVSPETSVDGNTLTLTLPGTRLPDALDRILDVSDFATPVSRIVPNRQDDAVTLTLENREPFQHLVTQRGDRLIVDVQPR
NEQTSDARDASPTYTGEPISLNFQNIQVREVLSVLSDFSGLNIVASDSVQGSVTLNLQQVPWDQALALILQSHGLASRRN
GDVIVVAPVDELAQMERQTLENRAQSEQLAPLVTDYVQVRYAKATDLAAMLRGSEGFGLLSERGRVTVDERTNTLLVRDT
REQLASIRGMLERLDVPVRQVQIEARIVIARDTASRELGVNWGISQRQGVTFDDDGVGSVVDRNPSGANRGSAGLSVDLG
DSDGSGSTFSFGYLSGDVLLDLELRALESEGKSQTISQPKVITANQKTAVIKQGQEIPYQESTSSGATNVEFKEAVLSLE
ATPQITPDGSIVMDLLINNDTVADNSYDGAPAIDTNSIETQVLVDDGATVVLGGILTSEQLRNLYKTPFLGDLPLIGSLF
RYTQESNEKVELLIFITPTIIGDGQANR
>Mature_668_residues
MMMRTLRGWLSGWLWLVGVIVCAQGQAATLTSLDIAQREDGGIDAMLGFDGPAPEAHSYRGDAPAQMIVDLPDTASGLEQ
RTVEVGQGGLRDISVVDAAERTRLVFGLTSPQAYSVQRQGDRLRVRLGSEAIPDGVTSIRDLDFRRGNAGGGRLVVTLDA
PGVSPETSVDGNTLTLTLPGTRLPDALDRILDVSDFATPVSRIVPNRQDDAVTLTLENREPFQHLVTQRGDRLIVDVQPR
NEQTSDARDASPTYTGEPISLNFQNIQVREVLSVLSDFSGLNIVASDSVQGSVTLNLQQVPWDQALALILQSHGLASRRN
GDVIVVAPVDELAQMERQTLENRAQSEQLAPLVTDYVQVRYAKATDLAAMLRGSEGFGLLSERGRVTVDERTNTLLVRDT
REQLASIRGMLERLDVPVRQVQIEARIVIARDTASRELGVNWGISQRQGVTFDDDGVGSVVDRNPSGANRGSAGLSVDLG
DSDGSGSTFSFGYLSGDVLLDLELRALESEGKSQTISQPKVITANQKTAVIKQGQEIPYQESTSSGATNVEFKEAVLSLE
ATPQITPDGSIVMDLLINNDTVADNSYDGAPAIDTNSIETQVLVDDGATVVLGGILTSEQLRNLYKTPFLGDLPLIGSLF
RYTQESNEKVELLIFITPTIIGDGQANR

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=413, Percent_Identity=37.046004842615, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI87082242, Length=403, Percent_Identity=30.272952853598, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 72073; Mature: 72073

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMRTLRGWLSGWLWLVGVIVCAQGQAATLTSLDIAQREDGGIDAMLGFDGPAPEAHSYR
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCEEEEEECCCCCCCCCCCC
GDAPAQMIVDLPDTASGLEQRTVEVGQGGLRDISVVDAAERTRLVFGLTSPQAYSVQRQG
CCCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCEEEECCCC
DRLRVRLGSEAIPDGVTSIRDLDFRRGNAGGGRLVVTLDAPGVSPETSVDGNTLTLTLPG
CEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECC
TRLPDALDRILDVSDFATPVSRIVPNRQDDAVTLTLENREPFQHLVTQRGDRLIVDVQPR
CCCHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCC
NEQTSDARDASPTYTGEPISLNFQNIQVREVLSVLSDFSGLNIVASDSVQGSVTLNLQQV
CCCCCCCCCCCCCCCCCCEEEEECCEEHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECC
PWDQALALILQSHGLASRRNGDVIVVAPVDELAQMERQTLENRAQSEQLAPLVTDYVQVR
CHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
YAKATDLAAMLRGSEGFGLLSERGRVTVDERTNTLLVRDTREQLASIRGMLERLDVPVRQ
ECCHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHCCCCEE
VQIEARIVIARDTASRELGVNWGISQRQGVTFDDDGVGSVVDRNPSGANRGSAGLSVDLG
EEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEEC
DSDGSGSTFSFGYLSGDVLLDLELRALESEGKSQTISQPKVITANQKTAVIKQGQEIPYQ
CCCCCCCEEEEEEECCCEEEEEEEEEHHCCCCCCCCCCCEEEECCCCEEEECCCCCCCCC
ESTSSGATNVEFKEAVLSLEATPQITPDGSIVMDLLINNDTVADNSYDGAPAIDTNSIET
CCCCCCCCCCHHHHHHHEECCCCCCCCCCCEEEEEEECCCEECCCCCCCCCCCCCCCCEE
QVLVDDGATVVLGGILTSEQLRNLYKTPFLGDLPLIGSLFRYTQESNEKVELLIFITPTI
EEEEECCCEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECEE
IGDGQANR
ECCCCCCC
>Mature Secondary Structure
MMMRTLRGWLSGWLWLVGVIVCAQGQAATLTSLDIAQREDGGIDAMLGFDGPAPEAHSYR
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCEEEEEECCCCCCCCCCCC
GDAPAQMIVDLPDTASGLEQRTVEVGQGGLRDISVVDAAERTRLVFGLTSPQAYSVQRQG
CCCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCEEEECCCC
DRLRVRLGSEAIPDGVTSIRDLDFRRGNAGGGRLVVTLDAPGVSPETSVDGNTLTLTLPG
CEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECC
TRLPDALDRILDVSDFATPVSRIVPNRQDDAVTLTLENREPFQHLVTQRGDRLIVDVQPR
CCCHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCC
NEQTSDARDASPTYTGEPISLNFQNIQVREVLSVLSDFSGLNIVASDSVQGSVTLNLQQV
CCCCCCCCCCCCCCCCCCEEEEECCEEHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECC
PWDQALALILQSHGLASRRNGDVIVVAPVDELAQMERQTLENRAQSEQLAPLVTDYVQVR
CHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
YAKATDLAAMLRGSEGFGLLSERGRVTVDERTNTLLVRDTREQLASIRGMLERLDVPVRQ
ECCHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHCCCCEE
VQIEARIVIARDTASRELGVNWGISQRQGVTFDDDGVGSVVDRNPSGANRGSAGLSVDLG
EEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEEC
DSDGSGSTFSFGYLSGDVLLDLELRALESEGKSQTISQPKVITANQKTAVIKQGQEIPYQ
CCCCCCCEEEEEEECCCEEEEEEEEEHHCCCCCCCCCCCEEEECCCCEEEECCCCCCCCC
ESTSSGATNVEFKEAVLSLEATPQITPDGSIVMDLLINNDTVADNSYDGAPAIDTNSIET
CCCCCCCCCCHHHHHHHEECCCCCCCCCCCEEEEEEECCCEECCCCCCCCCCCCCCCCEE
QVLVDDGATVVLGGILTSEQLRNLYKTPFLGDLPLIGSLFRYTQESNEKVELLIFITPTI
EEEEECCCEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECEE
IGDGQANR
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]