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The map label for this gene is yedX [C]

Identifier: 92112203

GI number: 92112203

Start: 87570

End: 87926

Strand: Direct

Name: yedX [C]

Synonym: Csal_0068

Alternate gene names: 92112203

Gene position: 87570-87926 (Clockwise)

Preceding gene: 92112199

Following gene: 92112204

Centisome position: 2.37

GC content: 66.95

Gene sequence:

>357_bases
ATGGGCTATCTCACCACGCACGTTCTGGACACCGCTCGGGGCTGCCCTGCACGCGGCATGCGCCTGTCGCTGTATCGGCT
CGATGGTGACACCCGCCAGGCGCTGGGCGAGTTCGTGACCAACGAGGATGGCCGTTGCGATGGCCCGCTGCTGGAGGGCG
AAGCCTTCCGGGTGGGCGAGTACGAGCTGCTGTTCGAGGCCGGCGAGTATCTCGATCGCCAGGATGAGGTCCCGCCGACG
GGGCCGCGCTTTCTGGCGCGGATTCCGCTGCGCTTCGGCATCGACGATGCGGGCGCCCACTACCATGTCCCGCTGTTGCT
GTCCCCCTTCGGTTATTCCACCTACCGCGGTAGCTGA

Upstream 100 bases:

>100_bases
TTCGGGATTGTTGTATACAAAAATCAGGGTAAGCGGTGGCGCCACGGGCGTCCATCCCGGGCTGCCGCTCGATGCCCGCC
GACGATCGCAAGGAGTGACC

Downstream 100 bases:

>100_bases
TGTCGGGCGGGCAATGCGATGATCAGCGCAAATGCATTCGGGAGCCGTGAATGAGCGAGTCACGTCAGGCGCATGCCGCC
AAGAAAACGCGTCGCAACGA

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase 2; HIUHase 2 [H]

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MGYLTTHVLDTARGCPARGMRLSLYRLDGDTRQALGEFVTNEDGRCDGPLLEGEAFRVGEYELLFEAGEYLDRQDEVPPT
GPRFLARIPLRFGIDDAGAHYHVPLLLSPFGYSTYRGS

Sequences:

>Translated_118_residues
MGYLTTHVLDTARGCPARGMRLSLYRLDGDTRQALGEFVTNEDGRCDGPLLEGEAFRVGEYELLFEAGEYLDRQDEVPPT
GPRFLARIPLRFGIDDAGAHYHVPLLLSPFGYSTYRGS
>Mature_117_residues
GYLTTHVLDTARGCPARGMRLSLYRLDGDTRQALGEFVTNEDGRCDGPLLEGEAFRVGEYELLFEAGEYLDRQDEVPPTG
PRFLARIPLRFGIDDAGAHYHVPLLLSPFGYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=115, Percent_Identity=36.5217391304348, Blast_Score=79, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115532922, Length=115, Percent_Identity=35.6521739130435, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532920, Length=115, Percent_Identity=35.6521739130435, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534555, Length=115, Percent_Identity=33.9130434782609, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652571, Length=117, Percent_Identity=38.4615384615385, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 13156; Mature: 13025

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00769 TRANSTHYRETIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYLTTHVLDTARGCPARGMRLSLYRLDGDTRQALGEFVTNEDGRCDGPLLEGEAFRVGE
CCCHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCEECCCEEECCC
YELLFEAGEYLDRQDEVPPTGPRFLARIPLRFGIDDAGAHYHVPLLLSPFGYSTYRGS
EEEEEHHHHHCCCCCCCCCCCCCEEEECCEEECCCCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
GYLTTHVLDTARGCPARGMRLSLYRLDGDTRQALGEFVTNEDGRCDGPLLEGEAFRVGE
CCHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCEECCCEEECCC
YELLFEAGEYLDRQDEVPPTGPRFLARIPLRFGIDDAGAHYHVPLLLSPFGYSTYRGS
EEEEEHHHHHCCCCCCCCCCCCCEEEECCEEECCCCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]