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The map label for this gene is pilE [H]

Identifier: 91790503

GI number: 91790503

Start: 4962936

End: 4963445

Strand: Reverse

Name: pilE [H]

Synonym: Bpro_4674

Alternate gene names: 91790503

Gene position: 4963445-4962936 (Counterclockwise)

Preceding gene: 91790505

Following gene: 91790502

Centisome position: 95.45

GC content: 54.12

Gene sequence:

>510_bases
ATGAAGCGTTCCATGCAAAAGGGTTTCACCCTGATCGAGTTGATGATCGTTGTGGCGATTATCGGTATTCTGGCTGCCGT
GGCTTTGCCTGCTTACCAGGATTACACGAAGCGCGCCAAGATGTCTGAAGTGATTTTGGCGGCTTCTTCCTGCCGTACCA
GTATTACTGAAACCATCCAGTCTGCGGCCTCTGGCAGTACCATCGCTGCGAATGGCTGGGGTTGCGAGGTGTCTACAGGT
TCGGGTACCAAGTATGTCGCCTCTATGGAAACCACGGCTAATAATCCTGGTGCTGCCGGCGGCGCGATGATTACCGTGAC
TGCCCAAAACATTGCTTCCGATGCAAATGGCGGGGTGTCTTTGGCGCCTTGCAGCACGGCTGCTACAACTTTTGGAACCT
GCTTGCAACCTGCGTTGGCTTCGACGGTTAATAGCTGGGTTTGCGGTCCTGCAGCGTCTGGTGGTGTTAATCCCAAGTTC
TTGCCTGGTTCTTGCCGCACCGGCCAATAA

Upstream 100 bases:

>100_bases
GACTGGTTAAAAAGCAGGAAAAAGTTCTCGAATTGGAGGCTTTGGCGAGCTGGCCCGAAACCTGCTCTATTTCATTGCTT
TTTCAACCAAGGAGTTTTCA

Downstream 100 bases:

>100_bases
GCTCGGATGATTCAAAAAGCGGCTCCGGCCGCTTTTTTTTATGACAGCTTCACGTTTCCATGCCTTCGGGGTTCTTTGTC
TTGCGTGGGCCTGGCTGGCG

Product: methylation

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MKRSMQKGFTLIELMIVVAIIGILAAVALPAYQDYTKRAKMSEVILAASSCRTSITETIQSAASGSTIAANGWGCEVSTG
SGTKYVASMETTANNPGAAGGAMITVTAQNIASDANGGVSLAPCSTAATTFGTCLQPALASTVNSWVCGPAASGGVNPKF
LPGSCRTGQ

Sequences:

>Translated_169_residues
MKRSMQKGFTLIELMIVVAIIGILAAVALPAYQDYTKRAKMSEVILAASSCRTSITETIQSAASGSTIAANGWGCEVSTG
SGTKYVASMETTANNPGAAGGAMITVTAQNIASDANGGVSLAPCSTAATTFGTCLQPALASTVNSWVCGPAASGGVNPKF
LPGSCRTGQ
>Mature_169_residues
MKRSMQKGFTLIELMIVVAIIGILAAVALPAYQDYTKRAKMSEVILAASSCRTSITETIQSAASGSTIAANGWGCEVSTG
SGTKYVASMETTANNPGAAGGAMITVTAQNIASDANGGVSLAPCSTAATTFGTCLQPALASTVNSWVCGPAASGGVNPKF
LPGSCRTGQ

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 16931; Mature: 16931

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSMQKGFTLIELMIVVAIIGILAAVALPAYQDYTKRAKMSEVILAASSCRTSITETIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAASGSTIAANGWGCEVSTGSGTKYVASMETTANNPGAAGGAMITVTAQNIASDANGGVS
HHCCCCEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEHHHHCCCCCCCEE
LAPCSTAATTFGTCLQPALASTVNSWVCGPAASGGVNPKFLPGSCRTGQ
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRSMQKGFTLIELMIVVAIIGILAAVALPAYQDYTKRAKMSEVILAASSCRTSITETIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAASGSTIAANGWGCEVSTGSGTKYVASMETTANNPGAAGGAMITVTAQNIASDANGGVS
HHCCCCEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEHHHHCCCCCCCEE
LAPCSTAATTFGTCLQPALASTVNSWVCGPAASGGVNPKFLPGSCRTGQ
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3141743; 10710307; 8645220; 8993351; 9515697 [H]