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The map label for this gene is dctS [H]

Identifier: 91790482

GI number: 91790482

Start: 4937953

End: 4940082

Strand: Reverse

Name: dctS [H]

Synonym: Bpro_4653

Alternate gene names: 91790482

Gene position: 4940082-4937953 (Counterclockwise)

Preceding gene: 91790483

Following gene: 91790481

Centisome position: 95.0

GC content: 66.43

Gene sequence:

>2130_bases
GTGAAATTTCCTCTTCTGAACGGTGTCAGCTGGGCCAGCCGGCGCTGGTCGCTCTGGGCCCTGCTGCTGGCGCTGGTGGT
GACGCTGCTGGCGATTCTTGTCTGGCTGTCGGGCCGCTACGAGTCCAGCATGGTGCAAAGCCGGCTGGAGCACGATGCGG
GAGAGACCGTCACGGACATCCGTTCGGGGCTGACCCGCAACATCCAGACGTTCCAGGCCTTGCAGTCCACGGAGCGCCCG
CCCGCCGCCTGGCATGCACCCGCCGCCGAGCTGCTGCGCGAGCATCGCGAGATCATGCGGCTGGAGTGGCGCAGCGAGAC
GCTGGAGGTGCTGGGATTTGTCGAGACGCCCTACCGGTCCTCGGTGTTTGAGCGCCTGGGTCGTCACGGCATGGAGGCCG
ATGTCAACCTGACCTGCACCACGGCTCGCCGCCTGAGCGGGTCGGCCTATTCCACCAGTTACTTCATGCCGCAAAACGAT
GGCCTGGGTCTGGAAGTCATGGACATGTGCTTGCCGATTGTGGCGGCGGGCCGACTGATGGGCTATGTGGTGGCCACCTA
TTCCCTGCAGGACATTCTGGGCGAACTGGTGGGCAAACAGCTGGCCCGCGGCGTCGGCCTCTCGTTCACGGAGGCCGATG
GCACGCGCCTGGCGCTGCATGGCGTGGTGTCGCGCGGCAGCCGGGTTTACGTCGCCCAGCAATTGCTCGACCTGCCGGGC
AACACGCTGGTCGTCAGGATGGAAAGCCGGCTCGGCACCCCCGCGCTGTTCCCCAATGTGCTGACGGCGCTGGTCACAGC
CATGTCGGTGGCCTTGCTGGCCGTGCTGTTCCTGCTGGCCCGCGACATGCGGCGGCGCCTCAAGGTGGAGCACGACCTGG
GCGAGGCCCTGGCCTTTCGCAAGGCCATGGAAGACTCGGTCCTGACGGGCCTGCGGGCGCGGGACCTGCAGGGGCGCATC
ACTTACGTCAATCCGGCGTTCTGCAAGATGGTGGGGGTGGATGCCAAGGACCTGCTCAACCAGAGCGTCCCTGCGCCCTA
CTGGCCGCCCGAGCTCGCAGCCATGTACCAGCAGCGCCAGGAAATCCGCCTGTCCGGCAGCAACCTGCCGCGTGAGGGCC
ATGAGTCCGTGTTCATGCGGCAGGACGGCACACGGTTTCCGGTGCTCATCATGGAGGCGCCGCTGATCAACGCGGTCGGC
AAGCACACCGGCTGGATGAGCGCCATTCTGGATGTCAGCGAACAGCGCCGCATTGAAGAGCTCTCGCGCGCCAGCCAGGA
CCGCCTGCAGGCCACGGCGAGGCTGGCGATGGTGGGAGAGATGGCATCGCTGCTCAGCCACGAACTCAACCAGCCGCTGG
CGGCCATTTCGAGCTATGCCACCGGCTCGCTCAACCTGCTGCAGGGCGAAATGGCGCCTGCCGCGACGTCTTCCCCGGGC
GGGCCGGATGCAGGCCCGACGGCACCGCCCCTGTCCGAAGACCTGCAACTGGCGATGCGGCGCATTGCCGAGCAGGCCGA
ACGGGCCGGCAAGGTGATCAAGAGCGTGCACGATTTTGTCCGGCGGCGCGACCAGGTACGCGAAGCCGTGGAGCCGCGGG
CCTTGCTGGACGCCATCATGCCGCTCGTCAGCCTGCAGGCCCGCAAGCTGGGCGTGCGCGTGGTGATCGAGGTGGACGCG
GCCTGCGAGCCGGTGCTGTGCGACCGCACCATGGTCGAGCAGGTGCTGCTCAACCTGTCGCGCAATGGCATGCAGGCCAT
GCAGGCCATGCAGGGTATAGACGAAACGCAGGCGCCCAACCAGCAGGCCAGAGTGCTCACCTTGCGTATCCGGCCGGCAG
CCTCCAATGCGCACAGCCGCTGGGTTGAATTTGCGGTGATTGACCGCGGTGAGGGCATTCCCCGTGAGGTGGCGGACCAG
CTTTTCACGCCCTTCTTCACGACCAAGGAGGAAGGCATGGGCCTGGGCCTGAGCCTGTGCCGCACGGTGATAGAGCAGCA
TGGCGGATTCCTGGGATTTGAAGCAGCGCAGCCGCGTGGCACGATTTTCAGTTTCACCTTGCCGGTGGCGCTGGCGCGGG
ATGGCCATGCCGATGTCGATGCCGCTGGTACCGCCAAGGAAATGGCCTAG

Upstream 100 bases:

>100_bases
GCGCGGCCGTGGTGATGGCCGAGGTTCTCCGCGCCGGCCTGGAGGGCGTGCGCAGCCGCTTGCCCGCCTTGCGCCACGGC
GTGTTGTGAAAGCGGCTGGC

Downstream 100 bases:

>100_bases
AGTACGCACCATGGAACCCATTCAAAATGCCACGGTTTATATCGTCGACGATGACGCCAGCGTACGCGATGCGCTGGCCT
GGCTGTTGCGGTCGCGTCGT

Product: signal transduction histidine kinase NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 709

Protein sequence:

>709_residues
MKFPLLNGVSWASRRWSLWALLLALVVTLLAILVWLSGRYESSMVQSRLEHDAGETVTDIRSGLTRNIQTFQALQSTERP
PAAWHAPAAELLREHREIMRLEWRSETLEVLGFVETPYRSSVFERLGRHGMEADVNLTCTTARRLSGSAYSTSYFMPQND
GLGLEVMDMCLPIVAAGRLMGYVVATYSLQDILGELVGKQLARGVGLSFTEADGTRLALHGVVSRGSRVYVAQQLLDLPG
NTLVVRMESRLGTPALFPNVLTALVTAMSVALLAVLFLLARDMRRRLKVEHDLGEALAFRKAMEDSVLTGLRARDLQGRI
TYVNPAFCKMVGVDAKDLLNQSVPAPYWPPELAAMYQQRQEIRLSGSNLPREGHESVFMRQDGTRFPVLIMEAPLINAVG
KHTGWMSAILDVSEQRRIEELSRASQDRLQATARLAMVGEMASLLSHELNQPLAAISSYATGSLNLLQGEMAPAATSSPG
GPDAGPTAPPLSEDLQLAMRRIAEQAERAGKVIKSVHDFVRRRDQVREAVEPRALLDAIMPLVSLQARKLGVRVVIEVDA
ACEPVLCDRTMVEQVLLNLSRNGMQAMQAMQGIDETQAPNQQARVLTLRIRPAASNAHSRWVEFAVIDRGEGIPREVADQ
LFTPFFTTKEEGMGLGLSLCRTVIEQHGGFLGFEAAQPRGTIFSFTLPVALARDGHADVDAAGTAKEMA

Sequences:

>Translated_709_residues
MKFPLLNGVSWASRRWSLWALLLALVVTLLAILVWLSGRYESSMVQSRLEHDAGETVTDIRSGLTRNIQTFQALQSTERP
PAAWHAPAAELLREHREIMRLEWRSETLEVLGFVETPYRSSVFERLGRHGMEADVNLTCTTARRLSGSAYSTSYFMPQND
GLGLEVMDMCLPIVAAGRLMGYVVATYSLQDILGELVGKQLARGVGLSFTEADGTRLALHGVVSRGSRVYVAQQLLDLPG
NTLVVRMESRLGTPALFPNVLTALVTAMSVALLAVLFLLARDMRRRLKVEHDLGEALAFRKAMEDSVLTGLRARDLQGRI
TYVNPAFCKMVGVDAKDLLNQSVPAPYWPPELAAMYQQRQEIRLSGSNLPREGHESVFMRQDGTRFPVLIMEAPLINAVG
KHTGWMSAILDVSEQRRIEELSRASQDRLQATARLAMVGEMASLLSHELNQPLAAISSYATGSLNLLQGEMAPAATSSPG
GPDAGPTAPPLSEDLQLAMRRIAEQAERAGKVIKSVHDFVRRRDQVREAVEPRALLDAIMPLVSLQARKLGVRVVIEVDA
ACEPVLCDRTMVEQVLLNLSRNGMQAMQAMQGIDETQAPNQQARVLTLRIRPAASNAHSRWVEFAVIDRGEGIPREVADQ
LFTPFFTTKEEGMGLGLSLCRTVIEQHGGFLGFEAAQPRGTIFSFTLPVALARDGHADVDAAGTAKEMA
>Mature_709_residues
MKFPLLNGVSWASRRWSLWALLLALVVTLLAILVWLSGRYESSMVQSRLEHDAGETVTDIRSGLTRNIQTFQALQSTERP
PAAWHAPAAELLREHREIMRLEWRSETLEVLGFVETPYRSSVFERLGRHGMEADVNLTCTTARRLSGSAYSTSYFMPQND
GLGLEVMDMCLPIVAAGRLMGYVVATYSLQDILGELVGKQLARGVGLSFTEADGTRLALHGVVSRGSRVYVAQQLLDLPG
NTLVVRMESRLGTPALFPNVLTALVTAMSVALLAVLFLLARDMRRRLKVEHDLGEALAFRKAMEDSVLTGLRARDLQGRI
TYVNPAFCKMVGVDAKDLLNQSVPAPYWPPELAAMYQQRQEIRLSGSNLPREGHESVFMRQDGTRFPVLIMEAPLINAVG
KHTGWMSAILDVSEQRRIEELSRASQDRLQATARLAMVGEMASLLSHELNQPLAAISSYATGSLNLLQGEMAPAATSSPG
GPDAGPTAPPLSEDLQLAMRRIAEQAERAGKVIKSVHDFVRRRDQVREAVEPRALLDAIMPLVSLQARKLGVRVVIEVDA
ACEPVLCDRTMVEQVLLNLSRNGMQAMQAMQGIDETQAPNQQARVLTLRIRPAASNAHSRWVEFAVIDRGEGIPREVADQ
LFTPFFTTKEEGMGLGLSLCRTVIEQHGGFLGFEAAQPRGTIFSFTLPVALARDGHADVDAAGTAKEMA

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=288, Percent_Identity=27.7777777777778, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788549, Length=408, Percent_Identity=24.5098039215686, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790300, Length=297, Percent_Identity=29.96632996633, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=422, Percent_Identity=23.696682464455, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77905; Mature: 77905

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPLLNGVSWASRRWSLWALLLALVVTLLAILVWLSGRYESSMVQSRLEHDAGETVTDI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
RSGLTRNIQTFQALQSTERPPAAWHAPAAELLREHREIMRLEWRSETLEVLGFVETPYRS
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SVFERLGRHGMEADVNLTCTTARRLSGSAYSTSYFMPQNDGLGLEVMDMCLPIVAAGRLM
HHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
GYVVATYSLQDILGELVGKQLARGVGLSFTEADGTRLALHGVVSRGSRVYVAQQLLDLPG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHHCCCCHHHHHHHHHCCC
NTLVVRMESRLGTPALFPNVLTALVTAMSVALLAVLFLLARDMRRRLKVEHDLGEALAFR
CEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAMEDSVLTGLRARDLQGRITYVNPAFCKMVGVDAKDLLNQSVPAPYWPPELAAMYQQRQ
HHHHHHHHHCCHHHCCCCEEEEECHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHH
EIRLSGSNLPREGHESVFMRQDGTRFPVLIMEAPLINAVGKHTGWMSAILDVSEQRRIEE
HHHCCCCCCCCCCCCCEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRASQDRLQATARLAMVGEMASLLSHELNQPLAAISSYATGSLNLLQGEMAPAATSSPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCC
GPDAGPTAPPLSEDLQLAMRRIAEQAERAGKVIKSVHDFVRRRDQVREAVEPRALLDAIM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
PLVSLQARKLGVRVVIEVDAACEPVLCDRTMVEQVLLNLSRNGMQAMQAMQGIDETQAPN
HHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
QQARVLTLRIRPAASNAHSRWVEFAVIDRGEGIPREVADQLFTPFFTTKEEGMGLGLSLC
CCCEEEEEEEECCCCCCHHHEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHH
RTVIEQHGGFLGFEAAQPRGTIFSFTLPVALARDGHADVDAAGTAKEMA
HHHHHHCCCEEEECCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure
MKFPLLNGVSWASRRWSLWALLLALVVTLLAILVWLSGRYESSMVQSRLEHDAGETVTDI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
RSGLTRNIQTFQALQSTERPPAAWHAPAAELLREHREIMRLEWRSETLEVLGFVETPYRS
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SVFERLGRHGMEADVNLTCTTARRLSGSAYSTSYFMPQNDGLGLEVMDMCLPIVAAGRLM
HHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
GYVVATYSLQDILGELVGKQLARGVGLSFTEADGTRLALHGVVSRGSRVYVAQQLLDLPG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHHCCCCHHHHHHHHHCCC
NTLVVRMESRLGTPALFPNVLTALVTAMSVALLAVLFLLARDMRRRLKVEHDLGEALAFR
CEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAMEDSVLTGLRARDLQGRITYVNPAFCKMVGVDAKDLLNQSVPAPYWPPELAAMYQQRQ
HHHHHHHHHCCHHHCCCCEEEEECHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHH
EIRLSGSNLPREGHESVFMRQDGTRFPVLIMEAPLINAVGKHTGWMSAILDVSEQRRIEE
HHHCCCCCCCCCCCCCEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRASQDRLQATARLAMVGEMASLLSHELNQPLAAISSYATGSLNLLQGEMAPAATSSPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCC
GPDAGPTAPPLSEDLQLAMRRIAEQAERAGKVIKSVHDFVRRRDQVREAVEPRALLDAIM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
PLVSLQARKLGVRVVIEVDAACEPVLCDRTMVEQVLLNLSRNGMQAMQAMQGIDETQAPN
HHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
QQARVLTLRIRPAASNAHSRWVEFAVIDRGEGIPREVADQLFTPFFTTKEEGMGLGLSLC
CCCEEEEEEEECCCCCCHHHEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHH
RTVIEQHGGFLGFEAAQPRGTIFSFTLPVALARDGHADVDAAGTAKEMA
HHHHHHCCCEEEECCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]