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The map label for this gene is yafV [C]

Identifier: 91790483

GI number: 91790483

Start: 4940094

End: 4940900

Strand: Reverse

Name: yafV [C]

Synonym: Bpro_4654

Alternate gene names: 91790483

Gene position: 4940900-4940094 (Counterclockwise)

Preceding gene: 91790484

Following gene: 91790482

Centisome position: 95.01

GC content: 66.54

Gene sequence:

>807_bases
ATGAAAGTCGCAGCCATCCAGATGGTTTCAGGCGTCCAGCTGCAGGACAACCTGGACATGGCCGGTCAGTTGCTGGGCCA
GGCCGCCGCACAGGGCGCCGAACTGGCGGTTCTGCCCGAATACTTCTGCATTATGGGCTTGAAGGACACCGACAAGCTCC
AGGTTCAGGAGACCGCCGGCCAGGGGCTGATCCAGGATTTCCTGAGCCACTCTGCGCGCGAACTCGGCATGTGGATCGTC
GGCGGCACGCTTCCGATGGCGACCACCGATCCGCGCCGTGCCCGCAACTGCTCACTGGCTTACGCCCCCTCGGGGGAATG
CGTGGCGCGCTACGACAAGATCCACCTGTTCCGTTTTGCACACGGCAAGGAAGACTACGACGAAACCCGCGTCCTCGAGC
CGGGCACTGCCCCGGTCCGTTTTGAGCTGGCCTCGCGGGACGGCCATGCCTACACCATTGGCATGAGCGTTTGCTACGAC
CTGCGGTTTCCGGAGCTGTACCGCGCGCTGAAGGCGGATGTGCTGCTGGTGCCCAGTGCGTTCACCTACACCACCGGGCA
GGCGCACTGGGAGGTGCTGCTGCGCGCGCGCGCGATCGAGAATCAGGCTTATGTGGTGGCTGCGGCGCAGGGCGGCACGC
ACGACAACGGCCGCCAAACCTGGGGCCACAGCATGGTGGTCGACCCGTGGGGCCAGGTTCTGGCCCAGCATGCCGAGGGC
GCGGCCGTGGTGATGGCCGAGGTTCTCCGCGCCGGCCTGGAGGGCGTGCGCAGCCGCTTGCCCGCCTTGCGCCACGGCGT
GTTGTGA

Upstream 100 bases:

>100_bases
ACATCCACGGCACCTGGTCCGATCCCAAAATCACCAAGCTTGAACGCAAGGCCGCGGCGGACAGCAAGGCTGGCGACACC
TCCACGGAGACCCGCTGATC

Downstream 100 bases:

>100_bases
AAGCGGCTGGCGTGAAATTTCCTCTTCTGAACGGTGTCAGCTGGGCCAGCCGGCGCTGGTCGCTCTGGGCCCTGCTGCTG
GCGCTGGTGGTGACGCTGCT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKVAAIQMVSGVQLQDNLDMAGQLLGQAAAQGAELAVLPEYFCIMGLKDTDKLQVQETAGQGLIQDFLSHSARELGMWIV
GGTLPMATTDPRRARNCSLAYAPSGECVARYDKIHLFRFAHGKEDYDETRVLEPGTAPVRFELASRDGHAYTIGMSVCYD
LRFPELYRALKADVLLVPSAFTYTTGQAHWEVLLRARAIENQAYVVAAAQGGTHDNGRQTWGHSMVVDPWGQVLAQHAEG
AAVVMAEVLRAGLEGVRSRLPALRHGVL

Sequences:

>Translated_268_residues
MKVAAIQMVSGVQLQDNLDMAGQLLGQAAAQGAELAVLPEYFCIMGLKDTDKLQVQETAGQGLIQDFLSHSARELGMWIV
GGTLPMATTDPRRARNCSLAYAPSGECVARYDKIHLFRFAHGKEDYDETRVLEPGTAPVRFELASRDGHAYTIGMSVCYD
LRFPELYRALKADVLLVPSAFTYTTGQAHWEVLLRARAIENQAYVVAAAQGGTHDNGRQTWGHSMVVDPWGQVLAQHAEG
AAVVMAEVLRAGLEGVRSRLPALRHGVL
>Mature_268_residues
MKVAAIQMVSGVQLQDNLDMAGQLLGQAAAQGAELAVLPEYFCIMGLKDTDKLQVQETAGQGLIQDFLSHSARELGMWIV
GGTLPMATTDPRRARNCSLAYAPSGECVARYDKIHLFRFAHGKEDYDETRVLEPGTAPVRFELASRDGHAYTIGMSVCYD
LRFPELYRALKADVLLVPSAFTYTTGQAHWEVLLRARAIENQAYVVAAAQGGTHDNGRQTWGHSMVVDPWGQVLAQHAEG
AAVVMAEVLRAGLEGVRSRLPALRHGVL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=270, Percent_Identity=39.6296296296296, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI297632348, Length=270, Percent_Identity=39.6296296296296, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI297632350, Length=270, Percent_Identity=39.6296296296296, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI9910460, Length=270, Percent_Identity=33.3333333333333, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI297632346, Length=196, Percent_Identity=34.1836734693878, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1786412, Length=236, Percent_Identity=33.4745762711864, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17556280, Length=268, Percent_Identity=37.3134328358209, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322335, Length=296, Percent_Identity=31.0810810810811, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6323383, Length=277, Percent_Identity=30.3249097472924, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17933642, Length=272, Percent_Identity=37.1323529411765, Blast_Score=151, Evalue=4e-37,
Organism=Drosophila melanogaster, GI21355835, Length=276, Percent_Identity=32.6086956521739, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29220; Mature: 29220

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAAIQMVSGVQLQDNLDMAGQLLGQAAAQGAELAVLPEYFCIMGLKDTDKLQVQETAG
CCEEEEEHHCCCEECCCCCHHHHHHHHHHHCCCCEEECCHHHHEECCCCCCCEEEHHHHC
QGLIQDFLSHSARELGMWIVGGTLPMATTDPRRARNCSLAYAPSGECVARYDKIHLFRFA
CHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHCCCEEEECCCCCHHHHHHHEEEEEEE
HGKEDYDETRVLEPGTAPVRFELASRDGHAYTIGMSVCYDLRFPELYRALKADVLLVPSA
CCCCCCCCCEEECCCCCCEEEEEECCCCCEEEEEEEHEEECCCHHHHHHHHCCEEEECCC
FTYTTGQAHWEVLLRARAIENQAYVVAAAQGGTHDNGRQTWGHSMVVDPWGQVLAQHAEG
EEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHCCC
AAVVMAEVLRAGLEGVRSRLPALRHGVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVAAIQMVSGVQLQDNLDMAGQLLGQAAAQGAELAVLPEYFCIMGLKDTDKLQVQETAG
CCEEEEEHHCCCEECCCCCHHHHHHHHHHHCCCCEEECCHHHHEECCCCCCCEEEHHHHC
QGLIQDFLSHSARELGMWIVGGTLPMATTDPRRARNCSLAYAPSGECVARYDKIHLFRFA
CHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHCCCEEEECCCCCHHHHHHHEEEEEEE
HGKEDYDETRVLEPGTAPVRFELASRDGHAYTIGMSVCYDLRFPELYRALKADVLLVPSA
CCCCCCCCCEEECCCCCCEEEEEECCCCCEEEEEEEHEEECCCHHHHHHHHCCEEEECCC
FTYTTGQAHWEVLLRARAIENQAYVVAAAQGGTHDNGRQTWGHSMVVDPWGQVLAQHAEG
EEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHCCC
AAVVMAEVLRAGLEGVRSRLPALRHGVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]