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The map label for this gene is dctR [H]

Identifier: 91790481

GI number: 91790481

Start: 4937316

End: 4937942

Strand: Reverse

Name: dctR [H]

Synonym: Bpro_4652

Alternate gene names: 91790481

Gene position: 4937942-4937316 (Counterclockwise)

Preceding gene: 91790482

Following gene: 91790480

Centisome position: 94.96

GC content: 62.84

Gene sequence:

>627_bases
ATGGAACCCATTCAAAATGCCACGGTTTATATCGTCGACGATGACGCCAGCGTACGCGATGCGCTGGCCTGGCTGTTGCG
GTCGCGTCGTCTGCCCAGTGAGACCTTCGACAGCGCCGAGGCCTTCGATGCGCGGGTGTCGCAGCAGTTTGAGGTGAAGT
CGCCTTCCTGCGTCCTGCTGGACGTGCGGATGGCGGGCCTGAGTGGTCTGGCCATGTTTGAGAAACTGATTGGCTACGGC
CTGCTGCCGACCCTGCCGGTGATTTTCCTGACGGGCCATGCGGATGTGCCGACGGCCGTCGATGCGGTCAAGCGTGGCGC
CTTTGATTTCTGCGAGAAGCCGTTTTCGGACAACGCACTCGTCGACCGCATCGAGCAGGCGCTCAAGTTTTCCGCGGCGG
CGCTGGCCCAGCACAGCGAATCGATCAGCCGGCAGGCGCGGCTGGACGGGCTGACCGACCGCGAGCGGGATGTGATGCGG
CTGGTGGTGGGCGGCCTGCCCAACAAGCTGGTGGCCGACCAGCTCGACATCAGTGTGCGGACGGTGGAAGTTCACCGTGC
CCGCGTTTTTGACAAAATGGGAGTCAAGTCGGCGGTAGAGCTTGCGAACCTGCTACGAAACCTGTAG

Upstream 100 bases:

>100_bases
ACGATTTTCAGTTTCACCTTGCCGGTGGCGCTGGCGCGGGATGGCCATGCCGATGTCGATGCCGCTGGTACCGCCAAGGA
AATGGCCTAGAGTACGCACC

Downstream 100 bases:

>100_bases
CGGGTTGGGTTTATTCCTTGTCGGCGCCGGCGTCTGATGCAGGGGGCACCGAATCGGCTTTCAGTTCGCCATTTTTTCGG
CCTGAAAACATCGTCCACCA

Product: two component LuxR family transcriptional regulator

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MEPIQNATVYIVDDDASVRDALAWLLRSRRLPSETFDSAEAFDARVSQQFEVKSPSCVLLDVRMAGLSGLAMFEKLIGYG
LLPTLPVIFLTGHADVPTAVDAVKRGAFDFCEKPFSDNALVDRIEQALKFSAAALAQHSESISRQARLDGLTDRERDVMR
LVVGGLPNKLVADQLDISVRTVEVHRARVFDKMGVKSAVELANLLRNL

Sequences:

>Translated_208_residues
MEPIQNATVYIVDDDASVRDALAWLLRSRRLPSETFDSAEAFDARVSQQFEVKSPSCVLLDVRMAGLSGLAMFEKLIGYG
LLPTLPVIFLTGHADVPTAVDAVKRGAFDFCEKPFSDNALVDRIEQALKFSAAALAQHSESISRQARLDGLTDRERDVMR
LVVGGLPNKLVADQLDISVRTVEVHRARVFDKMGVKSAVELANLLRNL
>Mature_208_residues
MEPIQNATVYIVDDDASVRDALAWLLRSRRLPSETFDSAEAFDARVSQQFEVKSPSCVLLDVRMAGLSGLAMFEKLIGYG
LLPTLPVIFLTGHADVPTAVDAVKRGAFDFCEKPFSDNALVDRIEQALKFSAAALAQHSESISRQARLDGLTDRERDVMR
LVVGGLPNKLVADQLDISVRTVEVHRARVFDKMGVKSAVELANLLRNL

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctR functions as a transcriptional repressor of genes for C4-dicarboxylate transport [H]

COG id: COG4566

COG function: function code T; Response regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=38.0952380952381, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22899; Mature: 22899

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIQNATVYIVDDDASVRDALAWLLRSRRLPSETFDSAEAFDARVSQQFEVKSPSCVLL
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEE
DVRMAGLSGLAMFEKLIGYGLLPTLPVIFLTGHADVPTAVDAVKRGAFDFCEKPFSDNAL
EEHHHCCHHHHHHHHHHCCCCHHHHHHEEEECCCCCCHHHHHHHHCHHHHHCCCCCCCHH
VDRIEQALKFSAAALAQHSESISRQARLDGLTDRERDVMRLVVGGLPNKLVADQLDISVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHCCEEE
TVEVHRARVFDKMGVKSAVELANLLRNL
HHHHHHHHHHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEPIQNATVYIVDDDASVRDALAWLLRSRRLPSETFDSAEAFDARVSQQFEVKSPSCVLL
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEE
DVRMAGLSGLAMFEKLIGYGLLPTLPVIFLTGHADVPTAVDAVKRGAFDFCEKPFSDNAL
EEHHHCCHHHHHHHHHHCCCCHHHHHHEEEECCCCCCHHHHHHHHCHHHHHCCCCCCCHH
VDRIEQALKFSAAALAQHSESISRQARLDGLTDRERDVMRLVVGGLPNKLVADQLDISVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHCCEEE
TVEVHRARVFDKMGVKSAVELANLLRNL
HHHHHHHHHHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]