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The map label for this gene is mltA [H]

Identifier: 91790480

GI number: 91790480

Start: 4935943

End: 4937211

Strand: Reverse

Name: mltA [H]

Synonym: Bpro_4651

Alternate gene names: 91790480

Gene position: 4937211-4935943 (Counterclockwise)

Preceding gene: 91790481

Following gene: 91790479

Centisome position: 94.94

GC content: 66.43

Gene sequence:

>1269_bases
ATGAACACCAGCAGCAGCAACGCCCCCAGGGCTTCGAGCAAAAGTAGGGCCATGACATTTCCTTGGATTGCAAACACCGT
TTCGCGGGAGCCGGTGCGATTCAGGTCAATTATCGCCACAGCCGCCGCCATCATCATGCTGCTGGCGTCCTGTGCCAGTC
CGCCCTACCGCACGCCGCCGCCCTCATCGCCCTCGCCCATGCCACCGGCCGCAGCGCCTGCCACTTCGGCTGCGGGGCCC
CGTCCGGGTGATACCGGGGCGTTGCCGGAGCCCATGGTGCAGGGCAAAAGCCGCTGGGTTGCCGTTCGCTGGGCGGACCT
GCCGGGGTTTGACGAGGACGCGCTGTTCGAGGCCTGGAACGCCTGGCTCAAAAGCTGCGAGCGGCCGGGGCCGGCATTTG
CCCCGCTGTGCGGCGAGGTGCGGCGCCTGAGCATTGCCCGGGCCGAAGACCAGCGTGCCTGGATGGTCGCTCGATTGCAG
CCTTACCGGGTCGAAACACTTCAGGGCGGTGCCGAAGGTTTGCTGACCAGTTATTACGAACCGGTGCTCAAGGCCAGCCG
TCAGCCGGGCAGTGGTTACGAGGTGCCCTTGTACCGGGTGCCGGCGTCGCTGGGCAGCCGCAAGCCCTGGTTCTCGCGGC
ATGAAATCGATACGCTGCCGGAGGCCCGTGTTGCCCTGAGGGGCCGGGAAATTGCCTGGCTGGCAGATCCGATCGAGGCG
ATGTCGCTGCACATCCAGGGCTCGGGCCGGTTGAACATCACGGAAGCGGATGGTTCGCAGCGGGTCGTGCGGGTGGCGTA
TGCCGGATCCAACGAGCAACCCTTTCGCAGCGTAACCCAATGGCTCCAGGATCAGGGCGAGGGCCGGATGACGGCGCCCT
GGATGGAGTCCACCAAGGCGTGGGCGGCGCGAAATCCGCAGCGCGTGCAGCAGATGCTGTGGAGCAATCCGCGCTACACG
TTTTTCCAGGAGCAGCCCCTGAGCGATCTGGACGCCGCATTCGGGCCGAAGGGCGCCCAGGGTGTGGCGTTGACGGCGGG
CCGCTCGATTGCAGTCGATCCGGGCAGCATTCCTTATGGCACACCGGTGTGGCTGGCGTCCCGCGGTAGCGCGGCCCAGT
TGCAGAAGCTGGTGTTTGCGCAAGATACCGGGAGTGCCATCGTGGGCGCGGTGCGCGCCGACTATTTTGCGGGGACCGGC
GCCGAAGCCGGCGAATTGGCCGCGCGGTTCAACCAGCCGCTGCGGCTTTGGGTGCTCTGGCCAAAATAG

Upstream 100 bases:

>100_bases
TTGGGTTTATTCCTTGTCGGCGCCGGCGTCTGATGCAGGGGGCACCGAATCGGCTTTCAGTTCGCCATTTTTTCGGCCTG
AAAACATCGTCCACCACACA

Downstream 100 bases:

>100_bases
CCAGAATGGTCAAACAGGCCAAAGAGTTGCCACGCCGGACACACACAGAGGACAGGGGGCACAGGATGCGCATCATGAAC
AAGCGTGCAGGCAGGCGGAT

Product: MltA

Products: Muramic Acid Residue [C]

Alternate protein names: Murein hydrolase A [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNTSSSNAPRASSKSRAMTFPWIANTVSREPVRFRSIIATAAAIIMLLASCASPPYRTPPPSSPSPMPPAAAPATSAAGP
RPGDTGALPEPMVQGKSRWVAVRWADLPGFDEDALFEAWNAWLKSCERPGPAFAPLCGEVRRLSIARAEDQRAWMVARLQ
PYRVETLQGGAEGLLTSYYEPVLKASRQPGSGYEVPLYRVPASLGSRKPWFSRHEIDTLPEARVALRGREIAWLADPIEA
MSLHIQGSGRLNITEADGSQRVVRVAYAGSNEQPFRSVTQWLQDQGEGRMTAPWMESTKAWAARNPQRVQQMLWSNPRYT
FFQEQPLSDLDAAFGPKGAQGVALTAGRSIAVDPGSIPYGTPVWLASRGSAAQLQKLVFAQDTGSAIVGAVRADYFAGTG
AEAGELAARFNQPLRLWVLWPK

Sequences:

>Translated_422_residues
MNTSSSNAPRASSKSRAMTFPWIANTVSREPVRFRSIIATAAAIIMLLASCASPPYRTPPPSSPSPMPPAAAPATSAAGP
RPGDTGALPEPMVQGKSRWVAVRWADLPGFDEDALFEAWNAWLKSCERPGPAFAPLCGEVRRLSIARAEDQRAWMVARLQ
PYRVETLQGGAEGLLTSYYEPVLKASRQPGSGYEVPLYRVPASLGSRKPWFSRHEIDTLPEARVALRGREIAWLADPIEA
MSLHIQGSGRLNITEADGSQRVVRVAYAGSNEQPFRSVTQWLQDQGEGRMTAPWMESTKAWAARNPQRVQQMLWSNPRYT
FFQEQPLSDLDAAFGPKGAQGVALTAGRSIAVDPGSIPYGTPVWLASRGSAAQLQKLVFAQDTGSAIVGAVRADYFAGTG
AEAGELAARFNQPLRLWVLWPK
>Mature_422_residues
MNTSSSNAPRASSKSRAMTFPWIANTVSREPVRFRSIIATAAAIIMLLASCASPPYRTPPPSSPSPMPPAAAPATSAAGP
RPGDTGALPEPMVQGKSRWVAVRWADLPGFDEDALFEAWNAWLKSCERPGPAFAPLCGEVRRLSIARAEDQRAWMVARLQ
PYRVETLQGGAEGLLTSYYEPVLKASRQPGSGYEVPLYRVPASLGSRKPWFSRHEIDTLPEARVALRGREIAWLADPIEA
MSLHIQGSGRLNITEADGSQRVVRVAYAGSNEQPFRSVTQWLQDQGEGRMTAPWMESTKAWAARNPQRVQQMLWSNPRYT
FFQEQPLSDLDAAFGPKGAQGVALTAGRSIAVDPGSIPYGTPVWLASRGSAAQLQKLVFAQDTGSAIVGAVRADYFAGTG
AEAGELAARFNQPLRLWVLWPK

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Note=In closely related bacteria this protein is attached to the outer membrane by a lipid anchor. This is apparently not the case here [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=256, Percent_Identity=31.640625, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 45884; Mature: 45884

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSSSNAPRASSKSRAMTFPWIANTVSREPVRFRSIIATAAAIIMLLASCASPPYRTPP
CCCCCCCCCCCCCCCCEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PSSPSPMPPAAAPATSAAGPRPGDTGALPEPMVQGKSRWVAVRWADLPGFDEDALFEAWN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCCHHHHHHHHH
AWLKSCERPGPAFAPLCGEVRRLSIARAEDQRAWMVARLQPYRVETLQGGAEGLLTSYYE
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCEEEHHHCCCHHHHHHHHHH
PVLKASRQPGSGYEVPLYRVPASLGSRKPWFSRHEIDTLPEARVALRGREIAWLADPIEA
HHHHHCCCCCCCCCCEEEECCHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCEE
MSLHIQGSGRLNITEADGSQRVVRVAYAGSNEQPFRSVTQWLQDQGEGRMTAPWMESTKA
EEEEEECCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEECCHHHHHHH
WAARNPQRVQQMLWSNPRYTFFQEQPLSDLDAAFGPKGAQGVALTAGRSIAVDPGSIPYG
HHCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCCCCEEEECCCEEEECCCCCCCC
TPVWLASRGSAAQLQKLVFAQDTGSAIVGAVRADYFAGTGAEAGELAARFNQPLRLWVLW
CCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEC
PK
CC
>Mature Secondary Structure
MNTSSSNAPRASSKSRAMTFPWIANTVSREPVRFRSIIATAAAIIMLLASCASPPYRTPP
CCCCCCCCCCCCCCCCEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PSSPSPMPPAAAPATSAAGPRPGDTGALPEPMVQGKSRWVAVRWADLPGFDEDALFEAWN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCCHHHHHHHHH
AWLKSCERPGPAFAPLCGEVRRLSIARAEDQRAWMVARLQPYRVETLQGGAEGLLTSYYE
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCEEEHHHCCCHHHHHHHHHH
PVLKASRQPGSGYEVPLYRVPASLGSRKPWFSRHEIDTLPEARVALRGREIAWLADPIEA
HHHHHCCCCCCCCCCEEEECCHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCEE
MSLHIQGSGRLNITEADGSQRVVRVAYAGSNEQPFRSVTQWLQDQGEGRMTAPWMESTKA
EEEEEECCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEECCHHHHHHH
WAARNPQRVQQMLWSNPRYTFFQEQPLSDLDAAFGPKGAQGVALTAGRSIAVDPGSIPYG
HHCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCCCCEEEECCCEEEECCCCCCCC
TPVWLASRGSAAQLQKLVFAQDTGSAIVGAVRADYFAGTGAEAGELAARFNQPLRLWVLW
CCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEC
PK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]