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The map label for this gene is dppA [H]

Identifier: 91790240

GI number: 91790240

Start: 4652035

End: 4653660

Strand: Reverse

Name: dppA [H]

Synonym: Bpro_4407

Alternate gene names: 91790240

Gene position: 4653660-4652035 (Counterclockwise)

Preceding gene: 91790242

Following gene: 91790239

Centisome position: 89.49

GC content: 58.67

Gene sequence:

>1626_bases
ATGGATCGTCGTGATTTCGTCAAAGGCGCAGCAGCTCTTACTGCAACCGCCGCCGCCGGCATCGGGCAAGCGCAACAAGC
CGGGGCGCCAGTTGCGAAGCGCTCAATTCTGACAGCTACCGCGCAGTTCGACCCGGCCCGCCCGGAGATTGCCCGGGTCG
TCGCACAGTCCTGCAAGTCGCTCGGGTGGGAGGTTGAAGCCAATCCCATCGACTACAACCAGGGCATCACGAAAGTGATC
AACGAGCATGACTTCGAGATGTTCCTGGTCTTTCTTCCGGGTACGGCCATCCGCATCGACCCCGACTTCTTCATTCGCAG
CGTTCACCACTCCACAGAGCATAAGCGCGGCGGCTTCAACTGGGCGGGCTACAAGAACGATCGGGTGGATGCTCTTGCGG
CCGTGCAGAGCCGCATGATGAACTTCAACGATCGCTGGAAGCCAGTCTTCGAAGCGCAGGACGTCATCTTCCAGGACCAG
CCTGGAACCGTGCTGGCCTATACGCAGATGACGATGGCTCATCGTTCGGACAAGCTCAAGGGCCTGGTGCCGCAGCTCGG
CGAGGGCATCGGCGGCTTTTGGTCTGACGTCAACATGGAAGTAGCGGGCGATGGCTACTCGCGTACGGGCTCAAACGCGG
ATGTGAAGCATCTGAATCCGCTCGCCGTTACCGACACGAGTGAGTTCATGGAGCTTTCCATGATCTATGACCGACTCTTT
CGCCTCGGACCGGATGGCAAACCTGTACCGTGGGCAGCCTCCGGAATGAAGTTGATCAACGACAGAACGATCGAGCTGAC
GATCCGCTCGGATATGCGCTGGCATGACGGCAAGCCAGTGACGGCCGAGGACGTCATGTTCACCTTCGACTATCACAAGA
AGTGGAAGGCGCCATTTTTCCTTGCCGCGCTCAATAATGTCGTCGCGGTGGAGCTCCCGAGCCCCAATACGGTGCGCATC
CGACTCGAAAATCCATCGGCTCCCTTTGTCTCCAACGTGATGGCGACGATGTTTCTTCTCCCCAAACACATTTGGGAAGG
CATCCCGGAGAAGGTCGGCATTGACGATCCGCTCAAATTCCCCAACGACAAGCCGGTCGGTAGCGGACCGTTCAAGTTCG
ACTACTGGCGGCGTGGCTCGGAACTCAAGGTCACCGCGTTCCGCGAGCACTTTAAACCGCCCAAGTGCGCTGGCATCATC
CGCGTCGTCTATGGCAGCCATGACGCTTTGGCCGCTGCCATCGAGAAGGGGGAATGCGACCGCTCACGCTATATCGTGTC
GCCAGCCCTCGTCAATCGCCTGAAAGCGGTGAAGAACGTAGTAGCCAAGGGCTATCCCAGCCACGGCCTCTATCACCTGG
CGTACAACAACAAGATCAAGCCTTTCGACGATCCCGTCTTTCGCCAGGCGCTCAACCATGTGATGCCGCGCAAGATGATC
TCGGAACTGATCCTGCTTGGATACGCTGATCCTGGTGCATCAATCATCTCGCCCATCAACGCGTTCTGGCACAACCCGGC
TGTCAAGGTTCCGGCCGAAGACGTGAAGAAGGCGCGCGACATTCTTGCGAAGGCCGGTTACGGATGGGACGCGCAAGGCA
AATTGCTCTCTCCCCGCGGCAAATGA

Upstream 100 bases:

>100_bases
TGGGTGGATAACGTAGCCACGCTTGGCGTGGACTTCCCCGAATCTTCGTTCATAGACTTGTCGCATAACGGGCTTGGGCC
TGATCAACTGAGGAGCAAGA

Downstream 100 bases:

>100_bases
CCTGAGCCCCACTGCGGCTGCTGACTCCTCCATTCGAACGCCTTCATATCACGGCGCGTTCAATGACAGAGTACGTCGCG
CGTCGCCTCTTCCTCGACGT

Product: twin-arginine translocation pathway signal protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MDRRDFVKGAAALTATAAAGIGQAQQAGAPVAKRSILTATAQFDPARPEIARVVAQSCKSLGWEVEANPIDYNQGITKVI
NEHDFEMFLVFLPGTAIRIDPDFFIRSVHHSTEHKRGGFNWAGYKNDRVDALAAVQSRMMNFNDRWKPVFEAQDVIFQDQ
PGTVLAYTQMTMAHRSDKLKGLVPQLGEGIGGFWSDVNMEVAGDGYSRTGSNADVKHLNPLAVTDTSEFMELSMIYDRLF
RLGPDGKPVPWAASGMKLINDRTIELTIRSDMRWHDGKPVTAEDVMFTFDYHKKWKAPFFLAALNNVVAVELPSPNTVRI
RLENPSAPFVSNVMATMFLLPKHIWEGIPEKVGIDDPLKFPNDKPVGSGPFKFDYWRRGSELKVTAFREHFKPPKCAGII
RVVYGSHDALAAAIEKGECDRSRYIVSPALVNRLKAVKNVVAKGYPSHGLYHLAYNNKIKPFDDPVFRQALNHVMPRKMI
SELILLGYADPGASIISPINAFWHNPAVKVPAEDVKKARDILAKAGYGWDAQGKLLSPRGK

Sequences:

>Translated_541_residues
MDRRDFVKGAAALTATAAAGIGQAQQAGAPVAKRSILTATAQFDPARPEIARVVAQSCKSLGWEVEANPIDYNQGITKVI
NEHDFEMFLVFLPGTAIRIDPDFFIRSVHHSTEHKRGGFNWAGYKNDRVDALAAVQSRMMNFNDRWKPVFEAQDVIFQDQ
PGTVLAYTQMTMAHRSDKLKGLVPQLGEGIGGFWSDVNMEVAGDGYSRTGSNADVKHLNPLAVTDTSEFMELSMIYDRLF
RLGPDGKPVPWAASGMKLINDRTIELTIRSDMRWHDGKPVTAEDVMFTFDYHKKWKAPFFLAALNNVVAVELPSPNTVRI
RLENPSAPFVSNVMATMFLLPKHIWEGIPEKVGIDDPLKFPNDKPVGSGPFKFDYWRRGSELKVTAFREHFKPPKCAGII
RVVYGSHDALAAAIEKGECDRSRYIVSPALVNRLKAVKNVVAKGYPSHGLYHLAYNNKIKPFDDPVFRQALNHVMPRKMI
SELILLGYADPGASIISPINAFWHNPAVKVPAEDVKKARDILAKAGYGWDAQGKLLSPRGK
>Mature_541_residues
MDRRDFVKGAAALTATAAAGIGQAQQAGAPVAKRSILTATAQFDPARPEIARVVAQSCKSLGWEVEANPIDYNQGITKVI
NEHDFEMFLVFLPGTAIRIDPDFFIRSVHHSTEHKRGGFNWAGYKNDRVDALAAVQSRMMNFNDRWKPVFEAQDVIFQDQ
PGTVLAYTQMTMAHRSDKLKGLVPQLGEGIGGFWSDVNMEVAGDGYSRTGSNADVKHLNPLAVTDTSEFMELSMIYDRLF
RLGPDGKPVPWAASGMKLINDRTIELTIRSDMRWHDGKPVTAEDVMFTFDYHKKWKAPFFLAALNNVVAVELPSPNTVRI
RLENPSAPFVSNVMATMFLLPKHIWEGIPEKVGIDDPLKFPNDKPVGSGPFKFDYWRRGSELKVTAFREHFKPPKCAGII
RVVYGSHDALAAAIEKGECDRSRYIVSPALVNRLKAVKNVVAKGYPSHGLYHLAYNNKIKPFDDPVFRQALNHVMPRKMI
SELILLGYADPGASIISPINAFWHNPAVKVPAEDVKKARDILAKAGYGWDAQGKLLSPRGK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=365, Percent_Identity=26.027397260274, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787052, Length=339, Percent_Identity=25.9587020648968, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787762, Length=294, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87082063, Length=164, Percent_Identity=31.0975609756098, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60156; Mature: 60156

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRDFVKGAAALTATAAAGIGQAQQAGAPVAKRSILTATAQFDPARPEIARVVAQSCKS
CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
LGWEVEANPIDYNQGITKVINEHDFEMFLVFLPGTAIRIDPDFFIRSVHHSTEHKRGGFN
CCCEEECCCCCCCCCHHHHHCCCCEEEEEEEECCCEEEECHHHHHHHHHHHHHHCCCCCC
WAGYKNDRVDALAAVQSRMMNFNDRWKPVFEAQDVIFQDQPGTVLAYTQMTMAHRSDKLK
CCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEECCCCCEEEEEHHHHHHHHHHHH
GLVPQLGEGIGGFWSDVNMEVAGDGYSRTGSNADVKHLNPLAVTDTSEFMELSMIYDRLF
HHHHHHCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHH
RLGPDGKPVPWAASGMKLINDRTIELTIRSDMRWHDGKPVTAEDVMFTFDYHKKWKAPFF
HCCCCCCCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCHHHEEEEEECCCCCCCCEE
LAALNNVVAVELPSPNTVRIRLENPSAPFVSNVMATMFLLPKHIWEGIPEKVGIDDPLKF
EEECCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PNDKPVGSGPFKFDYWRRGSELKVTAFREHFKPPKCAGIIRVVYGSHDALAAAIEKGECD
CCCCCCCCCCCEEHHHCCCCCEEEEEHHHHCCCCCHHHEEEEEECCCHHHHHHHHCCCCC
RSRYIVSPALVNRLKAVKNVVAKGYPSHGLYHLAYNNKIKPFDDPVFRQALNHVMPRKMI
CCEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
SELILLGYADPGASIISPINAFWHNPAVKVPAEDVKKARDILAKAGYGWDAQGKLLSPRG
HHHHHEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
K
C
>Mature Secondary Structure
MDRRDFVKGAAALTATAAAGIGQAQQAGAPVAKRSILTATAQFDPARPEIARVVAQSCKS
CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
LGWEVEANPIDYNQGITKVINEHDFEMFLVFLPGTAIRIDPDFFIRSVHHSTEHKRGGFN
CCCEEECCCCCCCCCHHHHHCCCCEEEEEEEECCCEEEECHHHHHHHHHHHHHHCCCCCC
WAGYKNDRVDALAAVQSRMMNFNDRWKPVFEAQDVIFQDQPGTVLAYTQMTMAHRSDKLK
CCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEECCCCCEEEEEHHHHHHHHHHHH
GLVPQLGEGIGGFWSDVNMEVAGDGYSRTGSNADVKHLNPLAVTDTSEFMELSMIYDRLF
HHHHHHCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHH
RLGPDGKPVPWAASGMKLINDRTIELTIRSDMRWHDGKPVTAEDVMFTFDYHKKWKAPFF
HCCCCCCCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCHHHEEEEEECCCCCCCCEE
LAALNNVVAVELPSPNTVRIRLENPSAPFVSNVMATMFLLPKHIWEGIPEKVGIDDPLKF
EEECCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PNDKPVGSGPFKFDYWRRGSELKVTAFREHFKPPKCAGIIRVVYGSHDALAAAIEKGECD
CCCCCCCCCCCEEHHHCCCCCEEEEEHHHHCCCCCHHHEEEEEECCCHHHHHHHHCCCCC
RSRYIVSPALVNRLKAVKNVVAKGYPSHGLYHLAYNNKIKPFDDPVFRQALNHVMPRKMI
CCEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
SELILLGYADPGASIISPINAFWHNPAVKVPAEDVKKARDILAKAGYGWDAQGKLLSPRG
HHHHHEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]