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The map label for this gene is dgoD [H]

Identifier: 91790193

GI number: 91790193

Start: 4596945

End: 4598105

Strand: Reverse

Name: dgoD [H]

Synonym: Bpro_4358

Alternate gene names: 91790193

Gene position: 4598105-4596945 (Counterclockwise)

Preceding gene: 91790194

Following gene: 91790191

Centisome position: 88.42

GC content: 55.99

Gene sequence:

>1161_bases
ATGAAAATAAGCAGCGTAAAGGTCTACTTGATCAAAAGCGGTCTACTGCACCCAGTCATCGTGCGAATCGACACCGACGA
GGGCATCTATGGCGTCGGCGAGGCTGCAATTGCGTATGGGTTAGGCGGAACAGCTGCTGCCGGCATGGTTAAAGACCTTG
CGAACCGGATTCTGATTGGCCGGGATCCGCACGCCATTGAAGCAATCTGGTCGGAGATGTATGACCATTCTTTCTGGGCA
AAGGGAGGCGGCCCCATCGTGTTCGCTGGCATCAGCGCCATCGAACAGGCCCTCTGGGACATCAAAGGTAAAGCGCTCAA
TGTCCCTGTCTACCAACTGCTGGGCGGCAAGGTTCGTGATGCCATCCGGGTCTACGCCAACGGGTGGAGCACCGAGGCAA
CGACAGCCGCAGATTTCGCGCGCGCCGCAGAGCGGCCACTCAAAGACGGCTATACGGCGCTGAAGTTCTACCCGCTGGCA
ATGCCAGACTCCAAAGGGACCATTTGTCACCCCACGCACCGGGCGCTGGATCGCGAGCAGGTACGTTTGGCTTTCGACCG
CGTGAGAGCTGTGTGCGATTTGGCTGGCCCGGATATCGACATCATGCTAGATCTAAGCGGCGCGCTGACTACGGACGAGA
CCATCCGGCTGTGCCAGCGCTACGAAGATCTGGGCATTGAGTTCATCGAGGAGCCGGCCGACCCATTTGACTTGGGCGCG
CTCAAGAAGATTTCAGAGAAGGTCAATATCCCCATCGCGGTGGGCGAACGTCTCTATACACGTTACGGTTTTCGCAAATT
AATGGAAATGCACGTAGCAGACACAGTCCAGCCGGATGTTGGTAATACCGGCGGCATCATGGAAACCAAGAAGATCGCGG
CAATGGCCGAGGCCTATAACCTGCGCGTCGCGCCGCACAACTGCGCGAGTCCAGTCTGCACCGCAGCAACATTGCACATC
GCGGCGAACGTGCCGAACTTTTCAATACTGGAAATGTATCCCTACTCGAATCGGCATTCCGGCTATCTAGAGTTCACCGA
CGTGATACCCGAGCACGAGGTGAAGAACGGGTACCTCAAAGTGCCGGACAAGCCCGGAATAGGCATCGAACTTATTGAGG
AAAAAATCGACACCTATCTTTGGGCAGAGATTAAAACATGA

Upstream 100 bases:

>100_bases
TGGGTCGTTGCCGATTACCGATTGCTGACAATCGGTAATTTGAAGGTGGCGGCTGAATTCCAACCACTTACGAGCGCAGC
GTCCGCTCTTTGGAGAAATT

Downstream 100 bases:

>100_bases
TTTGCGAGGGCGGGCTGAACCGACATGAGGCGGAACCCGCCGCGCCAGGATACGAGCCGCCTGCGTCCCCGTCCATTTAA
CGGAGTAGAGCCGTTACCTC

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKISSVKVYLIKSGLLHPVIVRIDTDEGIYGVGEAAIAYGLGGTAAAGMVKDLANRILIGRDPHAIEAIWSEMYDHSFWA
KGGGPIVFAGISAIEQALWDIKGKALNVPVYQLLGGKVRDAIRVYANGWSTEATTAADFARAAERPLKDGYTALKFYPLA
MPDSKGTICHPTHRALDREQVRLAFDRVRAVCDLAGPDIDIMLDLSGALTTDETIRLCQRYEDLGIEFIEEPADPFDLGA
LKKISEKVNIPIAVGERLYTRYGFRKLMEMHVADTVQPDVGNTGGIMETKKIAAMAEAYNLRVAPHNCASPVCTAATLHI
AANVPNFSILEMYPYSNRHSGYLEFTDVIPEHEVKNGYLKVPDKPGIGIELIEEKIDTYLWAEIKT

Sequences:

>Translated_386_residues
MKISSVKVYLIKSGLLHPVIVRIDTDEGIYGVGEAAIAYGLGGTAAAGMVKDLANRILIGRDPHAIEAIWSEMYDHSFWA
KGGGPIVFAGISAIEQALWDIKGKALNVPVYQLLGGKVRDAIRVYANGWSTEATTAADFARAAERPLKDGYTALKFYPLA
MPDSKGTICHPTHRALDREQVRLAFDRVRAVCDLAGPDIDIMLDLSGALTTDETIRLCQRYEDLGIEFIEEPADPFDLGA
LKKISEKVNIPIAVGERLYTRYGFRKLMEMHVADTVQPDVGNTGGIMETKKIAAMAEAYNLRVAPHNCASPVCTAATLHI
AANVPNFSILEMYPYSNRHSGYLEFTDVIPEHEVKNGYLKVPDKPGIGIELIEEKIDTYLWAEIKT
>Mature_386_residues
MKISSVKVYLIKSGLLHPVIVRIDTDEGIYGVGEAAIAYGLGGTAAAGMVKDLANRILIGRDPHAIEAIWSEMYDHSFWA
KGGGPIVFAGISAIEQALWDIKGKALNVPVYQLLGGKVRDAIRVYANGWSTEATTAADFARAAERPLKDGYTALKFYPLA
MPDSKGTICHPTHRALDREQVRLAFDRVRAVCDLAGPDIDIMLDLSGALTTDETIRLCQRYEDLGIEFIEEPADPFDLGA
LKKISEKVNIPIAVGERLYTRYGFRKLMEMHVADTVQPDVGNTGGIMETKKIAAMAEAYNLRVAPHNCASPVCTAATLHI
AANVPNFSILEMYPYSNRHSGYLEFTDVIPEHEVKNGYLKVPDKPGIGIELIEEKIDTYLWAEIKT

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=397, Percent_Identity=21.6624685138539, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI48994953, Length=380, Percent_Identity=33.6842105263158, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1787864, Length=393, Percent_Identity=31.8066157760814, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI226510960, Length=344, Percent_Identity=28.1976744186047, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 42395; Mature: 42395

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISSVKVYLIKSGLLHPVIVRIDTDEGIYGVGEAAIAYGLGGTAAAGMVKDLANRILIG
CCCCCEEEEEEECCCCCEEEEEEECCCCCEECCHHHHHHCCCCHHHHHHHHHHHHHEEEC
RDPHAIEAIWSEMYDHSFWAKGGGPIVFAGISAIEQALWDIKGKALNVPVYQLLGGKVRD
CCCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCEECCCHHHHHCCHHHH
AIRVYANGWSTEATTAADFARAAERPLKDGYTALKFYPLAMPDSKGTICHPTHRALDREQ
HHHEEECCCCCCCHHHHHHHHHHCCCHHCCCEEEEEEEEECCCCCCCEECCHHHHCCHHH
VRLAFDRVRAVCDLAGPDIDIMLDLSGALTTDETIRLCQRYEDLGIEFIEEPADPFDLGA
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCHHH
LKKISEKVNIPIAVGERLYTRYGFRKLMEMHVADTVQPDVGNTGGIMETKKIAAMAEAYN
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHE
LRVAPHNCASPVCTAATLHIAANVPNFSILEMYPYSNRHSGYLEFTDVIPEHEVKNGYLK
EEECCCCCCCCHHHHEEEEEEECCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEE
VPDKPGIGIELIEEKIDTYLWAEIKT
CCCCCCCCHHHHHHHHHHEEEEEECC
>Mature Secondary Structure
MKISSVKVYLIKSGLLHPVIVRIDTDEGIYGVGEAAIAYGLGGTAAAGMVKDLANRILIG
CCCCCEEEEEEECCCCCEEEEEEECCCCCEECCHHHHHHCCCCHHHHHHHHHHHHHEEEC
RDPHAIEAIWSEMYDHSFWAKGGGPIVFAGISAIEQALWDIKGKALNVPVYQLLGGKVRD
CCCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCEECCCHHHHHCCHHHH
AIRVYANGWSTEATTAADFARAAERPLKDGYTALKFYPLAMPDSKGTICHPTHRALDREQ
HHHEEECCCCCCCHHHHHHHHHHCCCHHCCCEEEEEEEEECCCCCCCEECCHHHHCCHHH
VRLAFDRVRAVCDLAGPDIDIMLDLSGALTTDETIRLCQRYEDLGIEFIEEPADPFDLGA
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCHHH
LKKISEKVNIPIAVGERLYTRYGFRKLMEMHVADTVQPDVGNTGGIMETKKIAAMAEAYN
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHE
LRVAPHNCASPVCTAATLHIAANVPNFSILEMYPYSNRHSGYLEFTDVIPEHEVKNGYLK
EEECCCCCCCCHHHHEEEEEEECCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEE
VPDKPGIGIELIEEKIDTYLWAEIKT
CCCCCCCCHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA