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The map label for this gene is yafC [H]

Identifier: 91790089

GI number: 91790089

Start: 4477443

End: 4478381

Strand: Direct

Name: yafC [H]

Synonym: Bpro_4251

Alternate gene names: 91790089

Gene position: 4477443-4478381 (Clockwise)

Preceding gene: 91790085

Following gene: 91790095

Centisome position: 86.1

GC content: 66.13

Gene sequence:

>939_bases
ATGCCCCGCATTGACGTCAACCGTTCCGGCGACATGGAAGCTTTTGTGCAGGTGGTGGAACGCGGCGGGTTTTCTGCAGC
GGCGCAAACCCTTTGCATGACACCTTCCGCTGTCAGCAAACTCATCACCCGGCTGGAAGCGCGCCTGGGCACCCGGCTGC
TGAACCGCTCGACCCGCAAGCTGCAAATAACGCCCGAAGGCACGACGTTTTACGAACACAGCACACGCGTGCTGGCCGAC
ATGGATGAAGCCGAGCGCAGTGCCGCCGCCAGTGCCGCGCCGCGCGGGCGCGTCAGCGTGAACGCCAGCATGCCGACGGG
CCACCACCTGCTGCTACCGCTGGTACCGGCCTTTCACGCACGTTTTCCCGACATCTTGCTCGACATCAGCCTGACCGACC
GCGTGGTGGACCTGCTGGACGAGCGCGCCGATGTGGCGATTCGCTGGGGCGCCCTGGCGTCTTCACAACTGGTGGCGCGG
CGCCTGGGCGACACGGCGCAGGTCATCGTCGGCGCGCCGGCTTACCTGGCGCGCCACGGCACACCGCAAACAATGCAAGA
GCTGGCAGCACACCAGCGCCTGGGCCACAACTACAAGCGCAACGCACCTTACTGGCCGTTGCGCGTGAACGGGCAACTGC
AGCAGCTGCCGATTGCCGGCTATGCGCGCGTGAGCGACGGCGAGGCGCTACGGCATCTGGCACTGGCCGGGGCCGGGCTG
GCCCGCATGTCGGTGTTTCACATTCAGGCCGATATCAAGGCCGGCCGGCTGGTGCCTGTGGCCGAACACTTGAACCCCGG
CGAGCGCGAACCAATTCATGCCGTGTTCTTGGGCAAAGGTGGCAGGCTGCCGGCGCGGGTCCGGGTGTTTCTGGACTTCC
TGGTAGCCGCGGTGACGCAAGAGGTGCTGGATGCCGGCGGTTTGATGGGGCAAGGCTGA

Upstream 100 bases:

>100_bases
CATGCCTTGTAGTGTGCGGACGCGGCACCATCTTGACTAGAATGACCAGATGAATATCACTCATGAATTGAATTCATGAA
TATCAGAGGAAAATTCCGCC

Downstream 100 bases:

>100_bases
GCCTCAAGCATTAGACTATTTCCCCCGAGGGAAAGCCGCTGGTGCGGTGCAGGCCTGCGGTCGATAGCCGTTCCTAAATC
TGCACCCGCGTCCCCAGTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPRIDVNRSGDMEAFVQVVERGGFSAAAQTLCMTPSAVSKLITRLEARLGTRLLNRSTRKLQITPEGTTFYEHSTRVLAD
MDEAERSAAASAAPRGRVSVNASMPTGHHLLLPLVPAFHARFPDILLDISLTDRVVDLLDERADVAIRWGALASSQLVAR
RLGDTAQVIVGAPAYLARHGTPQTMQELAAHQRLGHNYKRNAPYWPLRVNGQLQQLPIAGYARVSDGEALRHLALAGAGL
ARMSVFHIQADIKAGRLVPVAEHLNPGEREPIHAVFLGKGGRLPARVRVFLDFLVAAVTQEVLDAGGLMGQG

Sequences:

>Translated_312_residues
MPRIDVNRSGDMEAFVQVVERGGFSAAAQTLCMTPSAVSKLITRLEARLGTRLLNRSTRKLQITPEGTTFYEHSTRVLAD
MDEAERSAAASAAPRGRVSVNASMPTGHHLLLPLVPAFHARFPDILLDISLTDRVVDLLDERADVAIRWGALASSQLVAR
RLGDTAQVIVGAPAYLARHGTPQTMQELAAHQRLGHNYKRNAPYWPLRVNGQLQQLPIAGYARVSDGEALRHLALAGAGL
ARMSVFHIQADIKAGRLVPVAEHLNPGEREPIHAVFLGKGGRLPARVRVFLDFLVAAVTQEVLDAGGLMGQG
>Mature_311_residues
PRIDVNRSGDMEAFVQVVERGGFSAAAQTLCMTPSAVSKLITRLEARLGTRLLNRSTRKLQITPEGTTFYEHSTRVLADM
DEAERSAAASAAPRGRVSVNASMPTGHHLLLPLVPAFHARFPDILLDISLTDRVVDLLDERADVAIRWGALASSQLVARR
LGDTAQVIVGAPAYLARHGTPQTMQELAAHQRLGHNYKRNAPYWPLRVNGQLQQLPIAGYARVSDGEALRHLALAGAGLA
RMSVFHIQADIKAGRLVPVAEHLNPGEREPIHAVFLGKGGRLPARVRVFLDFLVAAVTQEVLDAGGLMGQG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=36.2068965517241, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=33.5548172757475, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=31.1643835616438, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789440, Length=299, Percent_Identity=27.7591973244147, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789639, Length=307, Percent_Identity=28.3387622149837, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=27.1477663230241, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787589, Length=265, Percent_Identity=29.811320754717, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789173, Length=239, Percent_Identity=29.2887029288703, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788481, Length=265, Percent_Identity=26.7924528301887, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788706, Length=186, Percent_Identity=29.5698924731183, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082132, Length=260, Percent_Identity=23.8461538461538, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=28.3870967741935, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33781; Mature: 33650

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRIDVNRSGDMEAFVQVVERGGFSAAAQTLCMTPSAVSKLITRLEARLGTRLLNRSTRK
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCE
LQITPEGTTFYEHSTRVLADMDEAERSAAASAAPRGRVSVNASMPTGHHLLLPLVPAFHA
EEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHHC
RFPDILLDISLTDRVVDLLDERADVAIRWGALASSQLVARRLGDTAQVIVGAPAYLARHG
CCCHHEEEECHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCEEEEECCCHHHHHCC
TPQTMQELAAHQRLGHNYKRNAPYWPLRVNGQLQQLPIAGYARVSDGEALRHLALAGAGL
CHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEECCCCCEEECCCHHHHHHHHHHCCCH
ARMSVFHIQADIKAGRLVPVAEHLNPGEREPIHAVFLGKGGRLPARVRVFLDFLVAAVTQ
HHHEEEEEEECCCCCCEEEEHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EVLDAGGLMGQG
HHHHCCCCCCCC
>Mature Secondary Structure 
PRIDVNRSGDMEAFVQVVERGGFSAAAQTLCMTPSAVSKLITRLEARLGTRLLNRSTRK
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCE
LQITPEGTTFYEHSTRVLADMDEAERSAAASAAPRGRVSVNASMPTGHHLLLPLVPAFHA
EEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHHC
RFPDILLDISLTDRVVDLLDERADVAIRWGALASSQLVARRLGDTAQVIVGAPAYLARHG
CCCHHEEEECHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCEEEEECCCHHHHHCC
TPQTMQELAAHQRLGHNYKRNAPYWPLRVNGQLQQLPIAGYARVSDGEALRHLALAGAGL
CHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEECCCCCEEECCCHHHHHHHHHHCCCH
ARMSVFHIQADIKAGRLVPVAEHLNPGEREPIHAVFLGKGGRLPARVRVFLDFLVAAVTQ
HHHEEEEEEECCCCCCEEEEHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EVLDAGGLMGQG
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]