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The map label for this gene is dsbD [H]

Identifier: 91790095

GI number: 91790095

Start: 4486167

End: 4488383

Strand: Direct

Name: dsbD [H]

Synonym: Bpro_4257

Alternate gene names: 91790095

Gene position: 4486167-4488383 (Clockwise)

Preceding gene: 91790089

Following gene: 91790096

Centisome position: 86.27

GC content: 66.98

Gene sequence:

>2217_bases
ATGCCGCCGTCCTTTGCTCACACATCCACCATGAATTTCAAGTGCTCTCCGTTTGCCGCGTTTTTTGCTTCTGTTTTGAT
AGCTGTTGGCGCAATAAGCACGCCGTCTCAGGCCCAGAATTTCCAGACAAACATCCTGAACCAGGGTAGCCGCAATGAGG
CGGGCGCACTGGTAACCACCGAGCAGGTGCGCGCCGAACTGCTGGCCTGGGCGCCCGAGGGCGTGGAGGCAGGCAAGCCG
GTCTGGCTGGGCCTGCAGCTGACGCACCAGCCCGAATGGCACACCTACTGGAAAAATTCCGGCGATTCCGGCCTGCCAAC
CCAGCTGACCTGGCAGCTGCCGGCCGGCATCACAGCAGGCGAGATCGCCTGGCCCACACCGAAAAAAATACCGGTGGGCA
CCTTGGCCAACTACGGCTATGAAAACACCGTGCTGCTGCCCGTGCCGCTGACGGTGGCGCCCACATTCAACGCTGCGCAG
CTCAACGTCAAGCTCCATGCCACCTGGCTGGTGTGCCGCAAGGAGTGCATCCCGCAGGAAGGCGAGTTCACGCTGAGCCT
GCCGGTCAAAAGCTCCACGGCGCTGAGCGGCCAGGCCTTTCAGGCCGCTTTTGCCGCCACGCCCACCGCCTTGCCGGCGG
GCGGCAGCCAGGTCGAAGTCAGCGGCAAGGCCATTAAGGTCGCCCTGAGCGGGCTGCCGGCTGGCCTGCAGGGCAAAACC
CTGGAATTTTTCCCCGAAACCGGCAGCGTGATTGAGCCGGCGGCGCCGTGGCAGCAAGCCTGGCAGGGCGCGGTGTGGAC
GGCGCAAGTGCCGCTGTCCGGCCAGCGTACCGCCAGCCCCGCGCAAATGCCGCTGGTGGTTGCTTTCAACCAGAGCGCTT
ATCGCATCGAAGCCCCCGTCAAGGGGACCTGGCCGGCCGTGGCCGCTGCCGCCGTGGTGCCGCCCGCGCTGGAAGCGGCC
CTGAAGGCCAATGCCTCGGCCGGTGCCGCGCCAGTGCAAAGCAGCGGGCCGCCCCTGAGCCTGCTGGCCGCGTTGTTCGG
CGCGCTGGTGGGAGGGATGATCCTGAACCTGATGCCCTGCGTGTTTCCGGTGCTGGCCATCAAGGTGGTGAGCTTTGTGC
ATGTGAAGGACCCGGGCACGCGCCTGAGCACTGGCCTGGCCTACACCGCCGGCGTGGTGCTGTCGTTTTTGGCGCTGGGC
GCCCTGCTGCTGGGCCTGCGCGCCGCGGGCGAGCAACTGGGCTGGGGCTTTCAGCTGCAAAACCCGGCGGTGGTGGCCGC
GCTGGCGGCCCTGTTCACGCTGCTGGGCCTGAACCTGGCGGGCCTCTTCGAGTTTGGCCACTTCCTGCCCGAACGGATCA
CCAGCCTGCAGTCCACGCGCCCGACCATCAACGCTTTCCTGTCGGGCGTGCTGGCCAGCGCGATTGCCTCCCCCTGTACC
GCGCCTTTCATGGGCGCCTCGCTGGGGTATGCGGTGGGCTTGCCGGCGCTGCAGGCGCTGGCCATGTTTGGCATGATCGG
CCTGGGCATGGCCTTGCCCTACCTGGCCGCCAGTGCGGTGCCGGCCGTGGCCCGCGTGTTGCCGCGTCCCGGCCACTGGA
TGGTGACCTTCCGCCAGCTGATGGCCTTTCCGATGTTTGCCACCGTGGCCTGGCTGGTCTGGGTGCTGGGCCAGCAAAGC
GGCATCGACGGCGCGGGCGCGCTGCTCGCCCTGCTGGTGCTGATGGCGCTGGTGCTCTGGTCGCTGACCCTGAAGGGTCG
GGCCCGGGCCGTATTTGCGACTTTTTCAATAGCGCTTGCCGCAATTGGGGTGCTGACTGTTGGCCAAACCATCACCAAGC
CTTTGCAGGCGTCCGCGGGGCCCGCGCTGGCCACCTCCGGAAGATGGCAGGCCTGGGAGCCGGGCCGCGTCGACCAGCTG
ACGGCCCAGGGCCAGAGCGTGCTGGTGGATTTCACCGCCGCATGGTGCGTCACCTGCCAGTACAACAAGAAAACGACGCT
GGCCAACACCGCCGTGCTGGCTGACATCGATGCGAAAAACGTCGCGCTGCTGCGCGCCGACTGGACACGCCGCGACCCGG
CGGTGACGGCGGCGCTGACCCAGCTGGGCCGCAGCGGCGTACCGGTGTATGCCATCTACAAACCAGGCCACGCGCCGGTC
ATCCTGTCGGAAGTGCTGTCGGTCGATGACCTGCGGACCGAACTGGCCAAGCTGTGA

Upstream 100 bases:

>100_bases
GCCATCCCTGAGTTTGCCCTGATTGGGCCCTCCTTCGATTGCGGGGCGACCCGTTTTGACAAACAGGCCCTCAAGAAAGG
CCAGGAACACCCCGGAACTA

Downstream 100 bases:

>100_bases
CCTTTGTACGAAGTGGTAACGCCGCGGATAAGGCCGTCAGAAAATGGTAAGTTAGCTAGTATAGTGACCCCTCACAGCCC
GTGAGGTATTTGCCATGACC

Product: thiol-disulfide interchange protein DsbD-like protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 738; Mature: 737

Protein sequence:

>738_residues
MPPSFAHTSTMNFKCSPFAAFFASVLIAVGAISTPSQAQNFQTNILNQGSRNEAGALVTTEQVRAELLAWAPEGVEAGKP
VWLGLQLTHQPEWHTYWKNSGDSGLPTQLTWQLPAGITAGEIAWPTPKKIPVGTLANYGYENTVLLPVPLTVAPTFNAAQ
LNVKLHATWLVCRKECIPQEGEFTLSLPVKSSTALSGQAFQAAFAATPTALPAGGSQVEVSGKAIKVALSGLPAGLQGKT
LEFFPETGSVIEPAAPWQQAWQGAVWTAQVPLSGQRTASPAQMPLVVAFNQSAYRIEAPVKGTWPAVAAAAVVPPALEAA
LKANASAGAAPVQSSGPPLSLLAALFGALVGGMILNLMPCVFPVLAIKVVSFVHVKDPGTRLSTGLAYTAGVVLSFLALG
ALLLGLRAAGEQLGWGFQLQNPAVVAALAALFTLLGLNLAGLFEFGHFLPERITSLQSTRPTINAFLSGVLASAIASPCT
APFMGASLGYAVGLPALQALAMFGMIGLGMALPYLAASAVPAVARVLPRPGHWMVTFRQLMAFPMFATVAWLVWVLGQQS
GIDGAGALLALLVLMALVLWSLTLKGRARAVFATFSIALAAIGVLTVGQTITKPLQASAGPALATSGRWQAWEPGRVDQL
TAQGQSVLVDFTAAWCVTCQYNKKTTLANTAVLADIDAKNVALLRADWTRRDPAVTAALTQLGRSGVPVYAIYKPGHAPV
ILSEVLSVDDLRTELAKL

Sequences:

>Translated_738_residues
MPPSFAHTSTMNFKCSPFAAFFASVLIAVGAISTPSQAQNFQTNILNQGSRNEAGALVTTEQVRAELLAWAPEGVEAGKP
VWLGLQLTHQPEWHTYWKNSGDSGLPTQLTWQLPAGITAGEIAWPTPKKIPVGTLANYGYENTVLLPVPLTVAPTFNAAQ
LNVKLHATWLVCRKECIPQEGEFTLSLPVKSSTALSGQAFQAAFAATPTALPAGGSQVEVSGKAIKVALSGLPAGLQGKT
LEFFPETGSVIEPAAPWQQAWQGAVWTAQVPLSGQRTASPAQMPLVVAFNQSAYRIEAPVKGTWPAVAAAAVVPPALEAA
LKANASAGAAPVQSSGPPLSLLAALFGALVGGMILNLMPCVFPVLAIKVVSFVHVKDPGTRLSTGLAYTAGVVLSFLALG
ALLLGLRAAGEQLGWGFQLQNPAVVAALAALFTLLGLNLAGLFEFGHFLPERITSLQSTRPTINAFLSGVLASAIASPCT
APFMGASLGYAVGLPALQALAMFGMIGLGMALPYLAASAVPAVARVLPRPGHWMVTFRQLMAFPMFATVAWLVWVLGQQS
GIDGAGALLALLVLMALVLWSLTLKGRARAVFATFSIALAAIGVLTVGQTITKPLQASAGPALATSGRWQAWEPGRVDQL
TAQGQSVLVDFTAAWCVTCQYNKKTTLANTAVLADIDAKNVALLRADWTRRDPAVTAALTQLGRSGVPVYAIYKPGHAPV
ILSEVLSVDDLRTELAKL
>Mature_737_residues
PPSFAHTSTMNFKCSPFAAFFASVLIAVGAISTPSQAQNFQTNILNQGSRNEAGALVTTEQVRAELLAWAPEGVEAGKPV
WLGLQLTHQPEWHTYWKNSGDSGLPTQLTWQLPAGITAGEIAWPTPKKIPVGTLANYGYENTVLLPVPLTVAPTFNAAQL
NVKLHATWLVCRKECIPQEGEFTLSLPVKSSTALSGQAFQAAFAATPTALPAGGSQVEVSGKAIKVALSGLPAGLQGKTL
EFFPETGSVIEPAAPWQQAWQGAVWTAQVPLSGQRTASPAQMPLVVAFNQSAYRIEAPVKGTWPAVAAAAVVPPALEAAL
KANASAGAAPVQSSGPPLSLLAALFGALVGGMILNLMPCVFPVLAIKVVSFVHVKDPGTRLSTGLAYTAGVVLSFLALGA
LLLGLRAAGEQLGWGFQLQNPAVVAALAALFTLLGLNLAGLFEFGHFLPERITSLQSTRPTINAFLSGVLASAIASPCTA
PFMGASLGYAVGLPALQALAMFGMIGLGMALPYLAASAVPAVARVLPRPGHWMVTFRQLMAFPMFATVAWLVWVLGQQSG
IDGAGALLALLVLMALVLWSLTLKGRARAVFATFSIALAAIGVLTVGQTITKPLQASAGPALATSGRWQAWEPGRVDQLT
AQGQSVLVDFTAAWCVTCQYNKKTTLANTAVLADIDAKNVALLRADWTRRDPAVTAALTQLGRSGVPVYAIYKPGHAPVI
LSEVLSVDDLRTELAKL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=509, Percent_Identity=27.3084479371316, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 77099; Mature: 76968

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSFAHTSTMNFKCSPFAAFFASVLIAVGAISTPSQAQNFQTNILNQGSRNEAGALVTT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEH
EQVRAELLAWAPEGVEAGKPVWLGLQLTHQPEWHTYWKNSGDSGLPTQLTWQLPAGITAG
HHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHCCCCCCCCCCCEEEEECCCCCCCC
EIAWPTPKKIPVGTLANYGYENTVLLPVPLTVAPTFNAAQLNVKLHATWLVCRKECIPQE
CCCCCCCCCCCCCHHHCCCCCCEEEEEECEEECCCCCCEEEEEEEEEHHHHHHHHHCCCC
GEFTLSLPVKSSTALSGQAFQAAFAATPTALPAGGSQVEVSGKAIKVALSGLPAGLQGKT
CCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCE
LEFFPETGSVIEPAAPWQQAWQGAVWTAQVPLSGQRTASPAQMPLVVAFNQSAYRIEAPV
EEECCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEECCC
KGTWPAVAAAAVVPPALEAALKANASAGAAPVQSSGPPLSLLAALFGALVGGMILNLMPC
CCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VFPVLAIKVVSFVHVKDPGTRLSTGLAYTAGVVLSFLALGALLLGLRAAGEQLGWGFQLQ
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NPAVVAALAALFTLLGLNLAGLFEFGHFLPERITSLQSTRPTINAFLSGVLASAIASPCT
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
APFMGASLGYAVGLPALQALAMFGMIGLGMALPYLAASAVPAVARVLPRPGHWMVTFRQL
CCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
MAFPMFATVAWLVWVLGQQSGIDGAGALLALLVLMALVLWSLTLKGRARAVFATFSIALA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AIGVLTVGQTITKPLQASAGPALATSGRWQAWEPGRVDQLTAQGQSVLVDFTAAWCVTCQ
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHHHHHCCCEEEEEEEEEEEEEEE
YNKKTTLANTAVLADIDAKNVALLRADWTRRDPAVTAALTQLGRSGVPVYAIYKPGHAPV
CCCCCEEECEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCH
ILSEVLSVDDLRTELAKL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPSFAHTSTMNFKCSPFAAFFASVLIAVGAISTPSQAQNFQTNILNQGSRNEAGALVTT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEH
EQVRAELLAWAPEGVEAGKPVWLGLQLTHQPEWHTYWKNSGDSGLPTQLTWQLPAGITAG
HHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHCCCCCCCCCCCEEEEECCCCCCCC
EIAWPTPKKIPVGTLANYGYENTVLLPVPLTVAPTFNAAQLNVKLHATWLVCRKECIPQE
CCCCCCCCCCCCCHHHCCCCCCEEEEEECEEECCCCCCEEEEEEEEEHHHHHHHHHCCCC
GEFTLSLPVKSSTALSGQAFQAAFAATPTALPAGGSQVEVSGKAIKVALSGLPAGLQGKT
CCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCE
LEFFPETGSVIEPAAPWQQAWQGAVWTAQVPLSGQRTASPAQMPLVVAFNQSAYRIEAPV
EEECCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEECCC
KGTWPAVAAAAVVPPALEAALKANASAGAAPVQSSGPPLSLLAALFGALVGGMILNLMPC
CCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VFPVLAIKVVSFVHVKDPGTRLSTGLAYTAGVVLSFLALGALLLGLRAAGEQLGWGFQLQ
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NPAVVAALAALFTLLGLNLAGLFEFGHFLPERITSLQSTRPTINAFLSGVLASAIASPCT
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
APFMGASLGYAVGLPALQALAMFGMIGLGMALPYLAASAVPAVARVLPRPGHWMVTFRQL
CCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
MAFPMFATVAWLVWVLGQQSGIDGAGALLALLVLMALVLWSLTLKGRARAVFATFSIALA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AIGVLTVGQTITKPLQASAGPALATSGRWQAWEPGRVDQLTAQGQSVLVDFTAAWCVTCQ
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHHHHHCCCEEEEEEEEEEEEEEE
YNKKTTLANTAVLADIDAKNVALLRADWTRRDPAVTAALTQLGRSGVPVYAIYKPGHAPV
CCCCCEEECEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCH
ILSEVLSVDDLRTELAKL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA