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The map label for this gene is lysN [H]

Identifier: 91790078

GI number: 91790078

Start: 4466820

End: 4468040

Strand: Direct

Name: lysN [H]

Synonym: Bpro_4240

Alternate gene names: 91790078

Gene position: 4466820-4468040 (Clockwise)

Preceding gene: 91790077

Following gene: 91790079

Centisome position: 85.9

GC content: 66.01

Gene sequence:

>1221_bases
ATGGAATGGACCCAAGCGCACCGCGCCCAAAAAATGAACCCCTCGGTGATCCGCGAGATTCTCAAGGTCACCGAGAAACC
CGGCATCATCAGCTTTGCCGGCGGGCTGCCTTCGCCCAAGACCTTTCCGGTCGCCGCCTTTCGCGAGGCCTGCGACAAGG
TGCTGCGTGAAGACGGCCATGCCGCGCTGCAGTACGCGGCCAGCGAAGGCTACGCCCCGCTGCGCGAGATGGTCGCGGCC
ATGTTGCCCTGGGATGTCGATCCGGCGCAGGTGCTGATCACCACCGGCTCGCAGCAGGGCCTGGATTTGATCGCCAAAAT
CCTGATCGATGCGGGCAGCCGCGTGCTGGTGGAAACGCCCACCTACCTGGGCGCGCTGCAGGCTTTCACGCCCATGGAAC
CCGACATCGTCAGCGTGGCCAGCGACGACGAAGGCGTGGACCTTGCCGATCTCGAACGCAAGGCGGCCGGCGCCCGTTTC
TTCTATGTGCTGCCCAATTTCCAGAACCCGACCGGCCGCACCATGACCGAAGAACGCCGTGCGGCGCTGAGCGCTGAAGC
CGCGCGCCTGGGTCTGCCCATCGTGGAAGACAACCCCTATGGCGATCTCTGGTTTGACAACCCGCCGCCGCTGCCGCTGA
CGGCACGCAACCCCGAGGGCTGTGTCTACCTCGGTTCGTTTTCCAAGGTGCTGGCGCCGGGGCTGCGGCTGGGCTTCATG
GTGGCGCCCAAGGCGCTCTACCCCAAGCTGCTGCAGGCCAAGCAGGCCGCCGACCTGCACAGCCCGGGTTTTAACCAGCG
CATGGTGGCTGAAGTCATGAAGGGCGGCTTTCTGGACCGCCATGTGCCGACCATACGGGCGCTCTACAAGTCGCAGCGCG
ATGCCATGCTGGCCGCGATGCAGCGCGAAATGCCCGAAGGCGTCACCTGGAACACGCCGGCGGGTGGCATGTTCCTGTGG
GCGCGCCTGCCCCAGGGCATGAATGCGGTGGACCTGTTGCCCCATGCCGTGGAGCGGGGTGTGGCCTTCGTACCCGGCGC
TGCGTTTTATGCGGACACGGCGGACGCGCGTACCCTGCGCCTGTCGTTTGTCACGGCAAGCGTGGAGCAGATCAATATCG
GCATCGCCGCACTGGCCGCCGCGATTCGCGAGCTGCAGGCACCTGCCGCGCCGGCGGCTTCACAGGCCGCGACGAATCAG
GCACTGGCAGCCAGCCTTTAA

Upstream 100 bases:

>100_bases
GCGTGCCTGCCGGCCGCCGGTGCGCCGCACCATGCTGACAACTTTGCAGAAGATTTTTTGACCAGGGCTGTCTTTTACGG
CCCGCAAGGAGGAGAGTGAA

Downstream 100 bases:

>100_bases
ACCGTCCAAAATTCGTCAACACTTCAGGAAAGACATCCAGCATGCTGCATATCTGGGGACGCATCAGCTCCATCAATGTC
AAGAAAGTCGTCTGGACCGC

Product: class I/II aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MEWTQAHRAQKMNPSVIREILKVTEKPGIISFAGGLPSPKTFPVAAFREACDKVLREDGHAALQYAASEGYAPLREMVAA
MLPWDVDPAQVLITTGSQQGLDLIAKILIDAGSRVLVETPTYLGALQAFTPMEPDIVSVASDDEGVDLADLERKAAGARF
FYVLPNFQNPTGRTMTEERRAALSAEAARLGLPIVEDNPYGDLWFDNPPPLPLTARNPEGCVYLGSFSKVLAPGLRLGFM
VAPKALYPKLLQAKQAADLHSPGFNQRMVAEVMKGGFLDRHVPTIRALYKSQRDAMLAAMQREMPEGVTWNTPAGGMFLW
ARLPQGMNAVDLLPHAVERGVAFVPGAAFYADTADARTLRLSFVTASVEQINIGIAALAAAIRELQAPAAPAASQAATNQ
ALAASL

Sequences:

>Translated_406_residues
MEWTQAHRAQKMNPSVIREILKVTEKPGIISFAGGLPSPKTFPVAAFREACDKVLREDGHAALQYAASEGYAPLREMVAA
MLPWDVDPAQVLITTGSQQGLDLIAKILIDAGSRVLVETPTYLGALQAFTPMEPDIVSVASDDEGVDLADLERKAAGARF
FYVLPNFQNPTGRTMTEERRAALSAEAARLGLPIVEDNPYGDLWFDNPPPLPLTARNPEGCVYLGSFSKVLAPGLRLGFM
VAPKALYPKLLQAKQAADLHSPGFNQRMVAEVMKGGFLDRHVPTIRALYKSQRDAMLAAMQREMPEGVTWNTPAGGMFLW
ARLPQGMNAVDLLPHAVERGVAFVPGAAFYADTADARTLRLSFVTASVEQINIGIAALAAAIRELQAPAAPAASQAATNQ
ALAASL
>Mature_406_residues
MEWTQAHRAQKMNPSVIREILKVTEKPGIISFAGGLPSPKTFPVAAFREACDKVLREDGHAALQYAASEGYAPLREMVAA
MLPWDVDPAQVLITTGSQQGLDLIAKILIDAGSRVLVETPTYLGALQAFTPMEPDIVSVASDDEGVDLADLERKAAGARF
FYVLPNFQNPTGRTMTEERRAALSAEAARLGLPIVEDNPYGDLWFDNPPPLPLTARNPEGCVYLGSFSKVLAPGLRLGFM
VAPKALYPKLLQAKQAADLHSPGFNQRMVAEVMKGGFLDRHVPTIRALYKSQRDAMLAAMQREMPEGVTWNTPAGGMFLW
ARLPQGMNAVDLLPHAVERGVAFVPGAAFYADTADARTLRLSFVTASVEQINIGIAALAAAIRELQAPAAPAASQAATNQ
ALAASL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=416, Percent_Identity=33.1730769230769, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI33469970, Length=416, Percent_Identity=33.1730769230769, Blast_Score=203, Evalue=3e-52,
Organism=Escherichia coli, GI1787710, Length=377, Percent_Identity=26.790450928382, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790797, Length=353, Percent_Identity=24.929178470255, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI48994949, Length=394, Percent_Identity=26.6497461928934, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788722, Length=346, Percent_Identity=28.0346820809249, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321000, Length=429, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321929, Length=423, Percent_Identity=23.6406619385343, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356535, Length=396, Percent_Identity=28.030303030303, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43658; Mature: 43658

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWTQAHRAQKMNPSVIREILKVTEKPGIISFAGGLPSPKTFPVAAFREACDKVLREDGH
CCCHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCH
AALQYAASEGYAPLREMVAAMLPWDVDPAQVLITTGSQQGLDLIAKILIDAGSRVLVETP
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECC
TYLGALQAFTPMEPDIVSVASDDEGVDLADLERKAAGARFFYVLPNFQNPTGRTMTEERR
HHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHH
AALSAEAARLGLPIVEDNPYGDLWFDNPPPLPLTARNPEGCVYLGSFSKVLAPGLRLGFM
HHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCEECCCCCCEEEECCCHHHHCCCHHHHHE
VAPKALYPKLLQAKQAADLHSPGFNQRMVAEVMKGGFLDRHVPTIRALYKSQRDAMLAAM
ECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QREMPEGVTWNTPAGGMFLWARLPQGMNAVDLLPHAVERGVAFVPGAAFYADTADARTLR
HHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEECCCCHHCCCCCCCEEEE
LSFVTASVEQINIGIAALAAAIRELQAPAAPAASQAATNQALAASL
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWTQAHRAQKMNPSVIREILKVTEKPGIISFAGGLPSPKTFPVAAFREACDKVLREDGH
CCCHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCH
AALQYAASEGYAPLREMVAAMLPWDVDPAQVLITTGSQQGLDLIAKILIDAGSRVLVETP
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECC
TYLGALQAFTPMEPDIVSVASDDEGVDLADLERKAAGARFFYVLPNFQNPTGRTMTEERR
HHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHH
AALSAEAARLGLPIVEDNPYGDLWFDNPPPLPLTARNPEGCVYLGSFSKVLAPGLRLGFM
HHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCEECCCCCCEEEECCCHHHHCCCHHHHHE
VAPKALYPKLLQAKQAADLHSPGFNQRMVAEVMKGGFLDRHVPTIRALYKSQRDAMLAAM
ECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QREMPEGVTWNTPAGGMFLWARLPQGMNAVDLLPHAVERGVAFVPGAAFYADTADARTLR
HHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEECCCCHHCCCCCCCEEEE
LSFVTASVEQINIGIAALAAAIRELQAPAAPAASQAATNQALAASL
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA