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The map label for this gene is coaX

Identifier: 91789883

GI number: 91789883

Start: 4245246

End: 4246013

Strand: Reverse

Name: coaX

Synonym: Bpro_4044

Alternate gene names: 91789883

Gene position: 4246013-4245246 (Counterclockwise)

Preceding gene: 91789884

Following gene: 91789880

Centisome position: 81.65

GC content: 66.02

Gene sequence:

>768_bases
ATGACCTTTCTTGCGCTTGACGTGGGCAACACCCGCCTGAAATGGGCCCAGTACGAGGCCCCTGCCGTCGGCGCCAGACT
GCTGGCGCATGGCGCCGTGTTTCTGGAAAACATCGACAGGCTCGCCGAGGAGGAGTGGAGCGAGATGTCGCCGCCGACCC
GGATTCTCGGCTGCATCGTGGCCGGCGACGCGATCAAACGCCGCGTGACGGAGCAGATGGAACTGTGGGATGTGGTGCCG
CGCTGGGTGGTGTCGAGCCCGCAGGAGGCCGGCCTGACCAACGGTTACGAGCATCCGGCGCGGCTGGGCGCTGACCGCTG
GGTGGCCATGATCGGTGCGCGCCATCGTCTGCTGGCCCGCGGCATCAGCAAGCCCTGCATCGTGGTCATGGTCGGCACGG
CCGTGACGGTCGAAGCCATAGACGCCTCCGGCAAATTTCTCGGTGGCATCATCCTGCCCGGCCACGGCATCATGCTGCGC
GCGCTCGAATCCGGCACGGCCGGCCTGCATGTGCCGACCGGCGAGGTCCGCGACTTTCCCACCAACACCAGTGACGCGCT
GACCAGTGGGGGAACCTTTGCGATTGCCGGCGCCGTGCAGCGCATGGTGGAAAACATCACCCGCCATTGCGGCGAGCCAC
CCGAGTGCATCATGACCGGCGGCGCGGGCTGGAAGATGGCGCCCAGCATGTCCGTCAAGTACGAACTGGTGGACAGCCTG
ATTTTTGATGGCTTGCTGGAAATCGCCTCGCGCCGCTTTGCGCCTTGA

Upstream 100 bases:

>100_bases
CTGGCGCCGCCGCGGGCGCATGCCTCCGAGGCTGACTACTGGTAAACCCTTTGATCCACAGGCGGCCGGGGTGTGGCAAA
TCTGTTCATAATCCAGCCAA

Downstream 100 bases:

>100_bases
GGCGGCAGCCGACAGGGCAGCCTGCCGTGGAGCTACCCGGCAAACAAGCGCTTATTTTTCGCTTTCCATGCGTACCAGCA
AATTCACCACATCGCGCTTT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTFLALDVGNTRLKWAQYEAPAVGARLLAHGAVFLENIDRLAEEEWSEMSPPTRILGCIVAGDAIKRRVTEQMELWDVVP
RWVVSSPQEAGLTNGYEHPARLGADRWVAMIGARHRLLARGISKPCIVVMVGTAVTVEAIDASGKFLGGIILPGHGIMLR
ALESGTAGLHVPTGEVRDFPTNTSDALTSGGTFAIAGAVQRMVENITRHCGEPPECIMTGGAGWKMAPSMSVKYELVDSL
IFDGLLEIASRRFAP

Sequences:

>Translated_255_residues
MTFLALDVGNTRLKWAQYEAPAVGARLLAHGAVFLENIDRLAEEEWSEMSPPTRILGCIVAGDAIKRRVTEQMELWDVVP
RWVVSSPQEAGLTNGYEHPARLGADRWVAMIGARHRLLARGISKPCIVVMVGTAVTVEAIDASGKFLGGIILPGHGIMLR
ALESGTAGLHVPTGEVRDFPTNTSDALTSGGTFAIAGAVQRMVENITRHCGEPPECIMTGGAGWKMAPSMSVKYELVDSL
IFDGLLEIASRRFAP
>Mature_254_residues
TFLALDVGNTRLKWAQYEAPAVGARLLAHGAVFLENIDRLAEEEWSEMSPPTRILGCIVAGDAIKRRVTEQMELWDVVPR
WVVSSPQEAGLTNGYEHPARLGADRWVAMIGARHRLLARGISKPCIVVMVGTAVTVEAIDASGKFLGGIILPGHGIMLRA
LESGTAGLHVPTGEVRDFPTNTSDALTSGGTFAIAGAVQRMVENITRHCGEPPECIMTGGAGWKMAPSMSVKYELVDSLI
FDGLLEIASRRFAP

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_POLSJ (Q124V5)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550835.1
- ProteinModelPortal:   Q124V5
- STRING:   Q124V5
- GeneID:   4013294
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_4044
- NMPDR:   fig|296591.1.peg.4106
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   RTTIRSR
- ProtClustDB:   PRK13329
- BioCyc:   PSP296591:BPRO_4044-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27446; Mature: 27315

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: ACT_SITE 105-105 BINDING 96-96 BINDING 133-133 BINDING 183-183

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLALDVGNTRLKWAQYEAPAVGARLLAHGAVFLENIDRLAEEEWSEMSPPTRILGCIV
CEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGDAIKRRVTEQMELWDVVPRWVVSSPQEAGLTNGYEHPARLGADRWVAMIGARHRLLAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHH
GISKPCIVVMVGTAVTVEAIDASGKFLGGIILPGHGIMLRALESGTAGLHVPTGEVRDFP
CCCCCEEEEEECCEEEEEEECCCCCEECEEEECCCCEEEEEECCCCCCEECCCCCCCCCC
TNTSDALTSGGTFAIAGAVQRMVENITRHCGEPPECIMTGGAGWKMAPSMSVKYELVDSL
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCCHHHHHHHHH
IFDGLLEIASRRFAP
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
TFLALDVGNTRLKWAQYEAPAVGARLLAHGAVFLENIDRLAEEEWSEMSPPTRILGCIV
EEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGDAIKRRVTEQMELWDVVPRWVVSSPQEAGLTNGYEHPARLGADRWVAMIGARHRLLAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHH
GISKPCIVVMVGTAVTVEAIDASGKFLGGIILPGHGIMLRALESGTAGLHVPTGEVRDFP
CCCCCEEEEEECCEEEEEEECCCCCEECEEEECCCCEEEEEECCCCCCEECCCCCCCCCC
TNTSDALTSGGTFAIAGAVQRMVENITRHCGEPPECIMTGGAGWKMAPSMSVKYELVDSL
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCCHHHHHHHHH
IFDGLLEIASRRFAP
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA