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The map label for this gene is abcA [H]

Identifier: 91789843

GI number: 91789843

Start: 4201215

End: 4202588

Strand: Direct

Name: abcA [H]

Synonym: Bpro_4003

Alternate gene names: 91789843

Gene position: 4201215-4202588 (Clockwise)

Preceding gene: 91789842

Following gene: 91789844

Centisome position: 80.79

GC content: 49.93

Gene sequence:

>1374_bases
ATGTCCTCTGACGATATTGCCATCACCGTTCAAGGCGTGTCCAAGCGCTATGAGCTTTACCACAAACCCAGTGACCAGCT
TAAGCAGTTCCTGCTGCCGCGGCTTCAGCGTCTCACAGGGCAACCCCAGCACCATTACTTTCAGGAGTTTTGGGCACTGA
AGGATGTTTCATTCGATATAAGAAGAGGTGAGGCCTTTGGCATCGTGGGCCGCAACGGTAGCGGTAAAAGCACGTTGCTC
CAGATCATTACTGGGACTCTTTCGCCAACAACCGGAACCGTTTCCACGAGGGGGCGGGTGGCAGCCTTGCTTGAGTTGGG
CTCTGGCTTCGACCCTGAATTCACCGGGCGTGAAAATATCTACATGAACGGGGCGCTACTGGGTTTTGATCGCCAGCAAA
TCGACCAGAAATTTGATGCCATCGCCGCGTTCGCCGACATAGGCTTGCACCTGGATCAGCCCATTAAGTCCTACTCAAGC
GGAATGGTGGTCCGCCTTGCCATTGCCGTGCAGACTCAGGTCGAGCCCGACATACTTATTGTTGATGAAGCACTCGCTGT
CGGCGATGCCCTATTTCAAAAACGCTGCTATCGACAGATCGACAAATTGCTGGATAACGGGTGCACCCTGCTTTTTGTGT
CTCATGATCAGGAAATAGTACGGACGCTCACGAGCAGGGCAGTCTTTTTGAATGCGGGACTCCCGGTCAAATATGGCGCC
ACAACCGACGTTTTATTTGCGTACCGGGAATTTCTTCAGCAACAGGAAGAGGCCGCCTTCCTTGATCTCCAGGAAAGGTC
CAAACAAGAGCTCTTGCCCCAACCCACCAAGAAATCTTATGGCAGGCGTGATGTTGAGATACTGGGTGTTGAAGTTCTTG
CATCCGATAAAACTCGACAAAGTGTGTTTTATGCGGGTGACACCATAACGATTGCTATCGAATGCGTTTGCAATACAGAT
ATTGAAAACCTCAATATTGCCTTTCGCATACTGAACAAGGAAGGCGTCAAGGTCACCACATGGGGGACATTGAATGAAGA
CATGCCCAACTTCCCCACCCATCTTCAAAGTACTTTTTGGAATAAGCACTTTTTCAAGGGCGACACATTTAAAGTGAACT
TTACCGGCAGTTGCAATCTCAGCGCAAATCTGTACGAGATACAAGCGACCGTGACACGAGAGCACGACCAGTACTACGGC
AATCAACAAGTGCTTCACTGGCTGGACGAAGCGAGCCACTTTACTGTGATCCTGAAAAACAAAGAATATGTTTTCGACGG
AATTTGTGATTTAGGTTTAAGGTCAAGCGTGGAACTGGGAAGTAGCACTTCAACGGTTGAGCCACATCAACCCATAACGC
CTTCTGCCTCCTGA

Upstream 100 bases:

>100_bases
TTGCCAGATTGGGTGGGGCTGGCAGCCTATAGCCTTGTTTCCGTATTTATTGCTTGGGTAGGTTATGCCTGGTTCCAGAA
AACCCGCAAAGGTTTTGCCA

Downstream 100 bases:

>100_bases
TAGCTGATTTATATGAAAATTTTCATTGATTCACTACTTCAACGACTTAAACGAGCACTTCGTGGCCGGCGGGCTGATCT
GCCTGCCTTGGTAGTTACAA

Product: ABC transporter-like protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSSDDIAITVQGVSKRYELYHKPSDQLKQFLLPRLQRLTGQPQHHYFQEFWALKDVSFDIRRGEAFGIVGRNGSGKSTLL
QIITGTLSPTTGTVSTRGRVAALLELGSGFDPEFTGRENIYMNGALLGFDRQQIDQKFDAIAAFADIGLHLDQPIKSYSS
GMVVRLAIAVQTQVEPDILIVDEALAVGDALFQKRCYRQIDKLLDNGCTLLFVSHDQEIVRTLTSRAVFLNAGLPVKYGA
TTDVLFAYREFLQQQEEAAFLDLQERSKQELLPQPTKKSYGRRDVEILGVEVLASDKTRQSVFYAGDTITIAIECVCNTD
IENLNIAFRILNKEGVKVTTWGTLNEDMPNFPTHLQSTFWNKHFFKGDTFKVNFTGSCNLSANLYEIQATVTREHDQYYG
NQQVLHWLDEASHFTVILKNKEYVFDGICDLGLRSSVELGSSTSTVEPHQPITPSAS

Sequences:

>Translated_457_residues
MSSDDIAITVQGVSKRYELYHKPSDQLKQFLLPRLQRLTGQPQHHYFQEFWALKDVSFDIRRGEAFGIVGRNGSGKSTLL
QIITGTLSPTTGTVSTRGRVAALLELGSGFDPEFTGRENIYMNGALLGFDRQQIDQKFDAIAAFADIGLHLDQPIKSYSS
GMVVRLAIAVQTQVEPDILIVDEALAVGDALFQKRCYRQIDKLLDNGCTLLFVSHDQEIVRTLTSRAVFLNAGLPVKYGA
TTDVLFAYREFLQQQEEAAFLDLQERSKQELLPQPTKKSYGRRDVEILGVEVLASDKTRQSVFYAGDTITIAIECVCNTD
IENLNIAFRILNKEGVKVTTWGTLNEDMPNFPTHLQSTFWNKHFFKGDTFKVNFTGSCNLSANLYEIQATVTREHDQYYG
NQQVLHWLDEASHFTVILKNKEYVFDGICDLGLRSSVELGSSTSTVEPHQPITPSAS
>Mature_456_residues
SSDDIAITVQGVSKRYELYHKPSDQLKQFLLPRLQRLTGQPQHHYFQEFWALKDVSFDIRRGEAFGIVGRNGSGKSTLLQ
IITGTLSPTTGTVSTRGRVAALLELGSGFDPEFTGRENIYMNGALLGFDRQQIDQKFDAIAAFADIGLHLDQPIKSYSSG
MVVRLAIAVQTQVEPDILIVDEALAVGDALFQKRCYRQIDKLLDNGCTLLFVSHDQEIVRTLTSRAVFLNAGLPVKYGAT
TDVLFAYREFLQQQEEAAFLDLQERSKQELLPQPTKKSYGRRDVEILGVEVLASDKTRQSVFYAGDTITIAIECVCNTDI
ENLNIAFRILNKEGVKVTTWGTLNEDMPNFPTHLQSTFWNKHFFKGDTFKVNFTGSCNLSANLYEIQATVTREHDQYYGN
QQVLHWLDEASHFTVILKNKEYVFDGICDLGLRSSVELGSSTSTVEPHQPITPSAS

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=205, Percent_Identity=29.7560975609756, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI30795238, Length=194, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI27881501, Length=194, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI153792144, Length=168, Percent_Identity=25, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI105990541, Length=193, Percent_Identity=24.8704663212435, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI150417984, Length=197, Percent_Identity=25.3807106598985, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI27262624, Length=281, Percent_Identity=23.1316725978648, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI27262626, Length=281, Percent_Identity=23.1316725978648, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI116734710, Length=195, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI6005701, Length=162, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI157502201, Length=244, Percent_Identity=26.6393442622951, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI157502203, Length=244, Percent_Identity=26.6393442622951, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1790467, Length=211, Percent_Identity=30.3317535545024, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789891, Length=218, Percent_Identity=28.4403669724771, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=25, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788210, Length=211, Percent_Identity=29.8578199052133, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI48995001, Length=204, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789032, Length=216, Percent_Identity=27.3148148148148, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788165, Length=216, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081782, Length=183, Percent_Identity=26.2295081967213, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082267, Length=203, Percent_Identity=25.1231527093596, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787089, Length=213, Percent_Identity=24.4131455399061, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786319, Length=253, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI48994943, Length=330, Percent_Identity=25.1515151515152, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=194, Percent_Identity=28.3505154639175, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786398, Length=259, Percent_Identity=24.3243243243243, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=211, Percent_Identity=23.2227488151659, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790525, Length=221, Percent_Identity=23.9819004524887, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788897, Length=209, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=206, Percent_Identity=27.1844660194175, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533608, Length=206, Percent_Identity=27.6699029126214, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71983516, Length=247, Percent_Identity=24.6963562753036, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=247, Percent_Identity=24.6963562753036, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=247, Percent_Identity=24.6963562753036, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=206, Percent_Identity=24.2718446601942, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221500365, Length=226, Percent_Identity=26.5486725663717, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116007184, Length=226, Percent_Identity=26.5486725663717, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643674, Length=248, Percent_Identity=25, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573571, Length=207, Percent_Identity=24.6376811594203, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573573, Length=207, Percent_Identity=24.6376811594203, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648314, Length=187, Percent_Identity=27.807486631016, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221512771, Length=191, Percent_Identity=25.130890052356, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=258, Percent_Identity=25.1937984496124, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 51243; Mature: 51111

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDDIAITVQGVSKRYELYHKPSDQLKQFLLPRLQRLTGQPQHHYFQEFWALKDVSFDI
CCCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEE
RRGEAFGIVGRNGSGKSTLLQIITGTLSPTTGTVSTRGRVAALLELGSGFDPEFTGRENI
ECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCCCCE
YMNGALLGFDRQQIDQKFDAIAAFADIGLHLDQPIKSYSSGMVVRLAIAVQTQVEPDILI
EECCEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEEEEEEECCCCCEEE
VDEALAVGDALFQKRCYRQIDKLLDNGCTLLFVSHDQEIVRTLTSRAVFLNAGLPVKYGA
EEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCEEEEECCCCEEECC
TTDVLFAYREFLQQQEEAAFLDLQERSKQELLPQPTKKSYGRRDVEILGVEVLASDKTRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEEEECCCCCC
SVFYAGDTITIAIECVCNTDIENLNIAFRILNKEGVKVTTWGTLNEDMPNFPTHLQSTFW
EEEEECCEEEEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHC
NKHFFKGDTFKVNFTGSCNLSANLYEIQATVTREHDQYYGNQQVLHWLDEASHFTVILKN
CCCCCCCCEEEEEEEECCCCCCEEEEEEEEEECCHHHHCCCHHHHHHHCCCCEEEEEEEC
KEYVFDGICDLGLRSSVELGSSTSTVEPHQPITPSAS
CCEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSDDIAITVQGVSKRYELYHKPSDQLKQFLLPRLQRLTGQPQHHYFQEFWALKDVSFDI
CCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEE
RRGEAFGIVGRNGSGKSTLLQIITGTLSPTTGTVSTRGRVAALLELGSGFDPEFTGRENI
ECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCCCCE
YMNGALLGFDRQQIDQKFDAIAAFADIGLHLDQPIKSYSSGMVVRLAIAVQTQVEPDILI
EECCEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEEEEEEECCCCCEEE
VDEALAVGDALFQKRCYRQIDKLLDNGCTLLFVSHDQEIVRTLTSRAVFLNAGLPVKYGA
EEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCEEEEECCCCEEECC
TTDVLFAYREFLQQQEEAAFLDLQERSKQELLPQPTKKSYGRRDVEILGVEVLASDKTRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEEEECCCCCC
SVFYAGDTITIAIECVCNTDIENLNIAFRILNKEGVKVTTWGTLNEDMPNFPTHLQSTFW
EEEEECCEEEEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHC
NKHFFKGDTFKVNFTGSCNLSANLYEIQATVTREHDQYYGNQQVLHWLDEASHFTVILKN
CCCCCCCCEEEEEEEECCCCCCEEEEEEEEEECCHHHHCCCHHHHHHHCCCCEEEEEEEC
KEYVFDGICDLGLRSSVELGSSTSTVEPHQPITPSAS
CCEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]