Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 91789640

GI number: 91789640

Start: 3981978

End: 3982907

Strand: Reverse

Name: livH [H]

Synonym: Bpro_3796

Alternate gene names: 91789640

Gene position: 3982907-3981978 (Counterclockwise)

Preceding gene: 91789641

Following gene: 91789639

Centisome position: 76.59

GC content: 61.61

Gene sequence:

>930_bases
ATGGAAGTATTGCTTCAGCAGATCATCAATGGTCTGGTACTGGGTAGCATGTATGCCCTGATCGCCCTGGGCTACACCAT
GGTCTACGGCATCATCAACCTGATCAATTTTGCGCATGGCGAGGTCTTGATGGTGGGTGCGCTGACCAGCTGGACCATCA
TCGGCCTGATGCAGGAGGCCATGCCGGGCACACCGGGCTGGCTGATCTTGCTGATTTCGCTGCTGATCGCCTTCGTGGTG
TGCGGTGCGCTGAATTTCGCGATTGAAAAAGTCGCCTACCGGCCGCTGCGCAATTCGCCCAAGCTGGCCCCGCTGATCAC
CGCCATTGGCATGTCGCTGCTGCTGCAGACGCTGGCCATGATGATCTGGAAGCCCAACTACAAACCTTACCCAACCCTCT
TGCCGACCGAGCCCTTCCAGGTGGGCGGCGCCGTGATCACCGTGACCCAGCTGTTCATTCTGGGTGCCACGGCGGTTTCT
CTCTCAGTGCTGATGTGGCTGGTGCATTACACCCGGCTGGGCCGTGCCATGCGCGCTACCGCCGAGAACCCGCGCGTGGC
GGCGCTGATGGGCGTGCGGCCCGATACCGTGATTTCCGCCACCTTCATCATCGGTGCCATTCTGGCGGCGCTGGCCGGCG
TGATGTACGCCTCCAATTACGGCACGGTGCAGCACACCATGGGCTTTTTGCCCGGTCTCAAGGCCTTTACGGCAGCCGTG
TTTGGCGGCATCGGCAACCTGGGCGGCGCGGTGCTGGGCGGCATCCTGCTGGGCCTGATTGAATCCATCGGTGCGGGCTA
CATCGGCCCGCTGACGGGTGGCGTGCTGGGCAGCCAGTACTCCGATATTTTTGCCTTTATCGTGCTGATTTTTGTGCTCA
CGCTGCGCCCATCCGGCCTGCTGGGTGAACGTGTGGCTGACCGGGCCTGA

Upstream 100 bases:

>100_bases
TTTTGTTAGCTCGCGCGATCCAGTGGTGATCCCATTGGTTCGTGGCCATTGTTGGCAAGAGGCAGAGTTGGCAAGTTCAA
TCAAACGGGAGAGTGAGTTT

Downstream 100 bases:

>100_bases
TCCCCGGTTGCCCTAAGGAGAAATTCTGATGAAACCCAACAAGCTGGTTACTTTTTTTATAGTTGCCGCCGCGCTGCTGG
TGTTGCCCCTGCTGTTGCAG

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MEVLLQQIINGLVLGSMYALIALGYTMVYGIINLINFAHGEVLMVGALTSWTIIGLMQEAMPGTPGWLILLISLLIAFVV
CGALNFAIEKVAYRPLRNSPKLAPLITAIGMSLLLQTLAMMIWKPNYKPYPTLLPTEPFQVGGAVITVTQLFILGATAVS
LSVLMWLVHYTRLGRAMRATAENPRVAALMGVRPDTVISATFIIGAILAALAGVMYASNYGTVQHTMGFLPGLKAFTAAV
FGGIGNLGGAVLGGILLGLIESIGAGYIGPLTGGVLGSQYSDIFAFIVLIFVLTLRPSGLLGERVADRA

Sequences:

>Translated_309_residues
MEVLLQQIINGLVLGSMYALIALGYTMVYGIINLINFAHGEVLMVGALTSWTIIGLMQEAMPGTPGWLILLISLLIAFVV
CGALNFAIEKVAYRPLRNSPKLAPLITAIGMSLLLQTLAMMIWKPNYKPYPTLLPTEPFQVGGAVITVTQLFILGATAVS
LSVLMWLVHYTRLGRAMRATAENPRVAALMGVRPDTVISATFIIGAILAALAGVMYASNYGTVQHTMGFLPGLKAFTAAV
FGGIGNLGGAVLGGILLGLIESIGAGYIGPLTGGVLGSQYSDIFAFIVLIFVLTLRPSGLLGERVADRA
>Mature_309_residues
MEVLLQQIINGLVLGSMYALIALGYTMVYGIINLINFAHGEVLMVGALTSWTIIGLMQEAMPGTPGWLILLISLLIAFVV
CGALNFAIEKVAYRPLRNSPKLAPLITAIGMSLLLQTLAMMIWKPNYKPYPTLLPTEPFQVGGAVITVTQLFILGATAVS
LSVLMWLVHYTRLGRAMRATAENPRVAALMGVRPDTVISATFIIGAILAALAGVMYASNYGTVQHTMGFLPGLKAFTAAV
FGGIGNLGGAVLGGILLGLIESIGAGYIGPLTGGVLGSQYSDIFAFIVLIFVLTLRPSGLLGERVADRA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=312, Percent_Identity=42.9487179487179, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 32639; Mature: 32639

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVLLQQIINGLVLGSMYALIALGYTMVYGIINLINFAHGEVLMVGALTSWTIIGLMQEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
MPGTPGWLILLISLLIAFVVCGALNFAIEKVAYRPLRNSPKLAPLITAIGMSLLLQTLAM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MIWKPNYKPYPTLLPTEPFQVGGAVITVTQLFILGATAVSLSVLMWLVHYTRLGRAMRAT
HHHCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENPRVAALMGVRPDTVISATFIIGAILAALAGVMYASNYGTVQHTMGFLPGLKAFTAAV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHH
FGGIGNLGGAVLGGILLGLIESIGAGYIGPLTGGVLGSQYSDIFAFIVLIFVLTLRPSGL
HHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LGERVADRA
HHHHHHCCC
>Mature Secondary Structure
MEVLLQQIINGLVLGSMYALIALGYTMVYGIINLINFAHGEVLMVGALTSWTIIGLMQEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
MPGTPGWLILLISLLIAFVVCGALNFAIEKVAYRPLRNSPKLAPLITAIGMSLLLQTLAM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MIWKPNYKPYPTLLPTEPFQVGGAVITVTQLFILGATAVSLSVLMWLVHYTRLGRAMRAT
HHHCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENPRVAALMGVRPDTVISATFIIGAILAALAGVMYASNYGTVQHTMGFLPGLKAFTAAV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHH
FGGIGNLGGAVLGGILLGLIESIGAGYIGPLTGGVLGSQYSDIFAFIVLIFVLTLRPSGL
HHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LGERVADRA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]