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The map label for this gene is mucB [H]

Identifier: 91789491

GI number: 91789491

Start: 3842761

End: 3843819

Strand: Reverse

Name: mucB [H]

Synonym: Bpro_3641

Alternate gene names: 91789491

Gene position: 3843819-3842761 (Counterclockwise)

Preceding gene: 91789492

Following gene: 91789490

Centisome position: 73.92

GC content: 57.98

Gene sequence:

>1059_bases
ATGAGCTTTTGCTGCGGCAGAGCCTTCAAAACAACCATGAATTTCAAGACTTATCGCCTTGTGGCCTTTTTTGTTTGGCC
ACTCGCCGCTATGAATTATGTAGCGGCCCAGGTGCCTTCGCCGGCCACGGCGTCCACGCCTGCCACGGCGGCGGAGTCCA
GAAGCGTCAATGACTGGTTGATGCGCATGCACGAGGCCTCCAAAAAACGCTCCTATATTGGGACTTTTGTTGTTTCGTCG
GGTGGCGCCATGTCGAGCGCAAAAGTCTGGCATGTCTGCGAAGGCAACCAGCAGGTGGAAAGGGTTGAAACCCTGACCGG
GGCGCCGCGCTCTATCTTCCGGCACAACGATCAGGTCGTTACATTCATGCCCGACCACAAGGTGGTGCGCAGCGAAAAAC
GGGAATCCCTGGGTATGTTTCCCGAGTTGCTCCAGTCAACCGACAGCCGCATTGCCGATTTCTACAAGATGCGGCATGAC
GGCGTAGAGCGGGTGGCTGGCGTCGAAGCGGACGTCGTGATGCTGGTTCCCAAGGACAGCATGCGTTTTGGCTACCGTAT
TTGGACCGAGCAAAAAAAGGGCCTGGTGGTGAAGTTGCAGACCCTGGACGCTGATGGCAAGGTGCTCGAGCAGGCCGCGT
TTTCGGAGCTGCAGCTCGATGCGCCGGTCAAAATGGACCAGCTTATCCAGATGATGGGCAAGGTGGACGGCTATCGCGTT
GAGAAGCCTGTGATGGTGAAGACCACGGCCAGCGCCGAAGGCTGGGTGCTCAAAGCGCCTGTTGCCGGGTTTAAACCCAT
GAGCTGCTACAAGCGCCCCGCGGCGAACGCCGCGCCAGGTGCCGAGCCTCTGCAATGGATTTTCTCCGACGGGCTGGCCT
CCGTCTCCATCTTTGTGGAACCCTATGACCGGCAACGCCATGAGAAGGAATCCAGCCTGTCACTGGGGGCCACCCAGACG
CTGACCAGGCAAGTGGACGCTTACTGGGTAACCATCATGGGTGAAGTTCCCATGGCAACTTTGCGCCATTTTGCCAATGG
GCTGGAGCGGAAAAAGTAG

Upstream 100 bases:

>100_bases
GGCCGCACACAAGCAGTTGGGTGGTGCATCCGCCTTGCAGGTGCCGTCGGGGTTTTTGCGAAACGCCACCTTTGAAACGC
CTCAGAATGCAGGGCGTTGA

Downstream 100 bases:

>100_bases
TCGGTGCCTGCGCGGGAGTTGTTGCCGGAAAATTTTCCGCGTGGGGCGCAGGTGCCGCATATTGCCCGTATTGTTTTTTC
TCTGGCGTCCCTATTTCCTT

Product: putative sigma E regulatory protein, MucB/RseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSFCCGRAFKTTMNFKTYRLVAFFVWPLAAMNYVAAQVPSPATASTPATAAESRSVNDWLMRMHEASKKRSYIGTFVVSS
GGAMSSAKVWHVCEGNQQVERVETLTGAPRSIFRHNDQVVTFMPDHKVVRSEKRESLGMFPELLQSTDSRIADFYKMRHD
GVERVAGVEADVVMLVPKDSMRFGYRIWTEQKKGLVVKLQTLDADGKVLEQAAFSELQLDAPVKMDQLIQMMGKVDGYRV
EKPVMVKTTASAEGWVLKAPVAGFKPMSCYKRPAANAAPGAEPLQWIFSDGLASVSIFVEPYDRQRHEKESSLSLGATQT
LTRQVDAYWVTIMGEVPMATLRHFANGLERKK

Sequences:

>Translated_352_residues
MSFCCGRAFKTTMNFKTYRLVAFFVWPLAAMNYVAAQVPSPATASTPATAAESRSVNDWLMRMHEASKKRSYIGTFVVSS
GGAMSSAKVWHVCEGNQQVERVETLTGAPRSIFRHNDQVVTFMPDHKVVRSEKRESLGMFPELLQSTDSRIADFYKMRHD
GVERVAGVEADVVMLVPKDSMRFGYRIWTEQKKGLVVKLQTLDADGKVLEQAAFSELQLDAPVKMDQLIQMMGKVDGYRV
EKPVMVKTTASAEGWVLKAPVAGFKPMSCYKRPAANAAPGAEPLQWIFSDGLASVSIFVEPYDRQRHEKESSLSLGATQT
LTRQVDAYWVTIMGEVPMATLRHFANGLERKK
>Mature_351_residues
SFCCGRAFKTTMNFKTYRLVAFFVWPLAAMNYVAAQVPSPATASTPATAAESRSVNDWLMRMHEASKKRSYIGTFVVSSG
GAMSSAKVWHVCEGNQQVERVETLTGAPRSIFRHNDQVVTFMPDHKVVRSEKRESLGMFPELLQSTDSRIADFYKMRHDG
VERVAGVEADVVMLVPKDSMRFGYRIWTEQKKGLVVKLQTLDADGKVLEQAAFSELQLDAPVKMDQLIQMMGKVDGYRVE
KPVMVKTTASAEGWVLKAPVAGFKPMSCYKRPAANAAPGAEPLQWIFSDGLASVSIFVEPYDRQRHEKESSLSLGATQTL
TRQVDAYWVTIMGEVPMATLRHFANGLERKK

Specific function: Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate- producing form. Inactivation of mucB causes conversion to mucoidy [H]

COG id: COG3026

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseB family [H]

Homologues:

Organism=Escherichia coli, GI1788924, Length=324, Percent_Identity=23.4567901234568, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005588 [H]

Pfam domain/function: PF03888 MucB_RseB [H]

EC number: NA

Molecular weight: Translated: 39308; Mature: 39177

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFCCGRAFKTTMNFKTYRLVAFFVWPLAAMNYVAAQVPSPATASTPATAAESRSVNDWL
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHH
MRMHEASKKRSYIGTFVVSSGGAMSSAKVWHVCEGNQQVERVETLTGAPRSIFRHNDQVV
HHHHHHHHHHHEEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHCCCCEE
TFMPDHKVVRSEKRESLGMFPELLQSTDSRIADFYKMRHDGVERVAGVEADVVMLVPKDS
EECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
MRFGYRIWTEQKKGLVVKLQTLDADGKVLEQAAFSELQLDAPVKMDQLIQMMGKVDGYRV
CCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEE
EKPVMVKTTASAEGWVLKAPVAGFKPMSCYKRPAANAAPGAEPLQWIFSDGLASVSIFVE
CCCEEEEEECCCCCCEEECCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEEC
PYDRQRHEKESSLSLGATQTLTRQVDAYWVTIMGEVPMATLRHFANGLERKK
CCHHHHHHHHHHCCCCHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFCCGRAFKTTMNFKTYRLVAFFVWPLAAMNYVAAQVPSPATASTPATAAESRSVNDWL
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHH
MRMHEASKKRSYIGTFVVSSGGAMSSAKVWHVCEGNQQVERVETLTGAPRSIFRHNDQVV
HHHHHHHHHHHEEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHCCCCEE
TFMPDHKVVRSEKRESLGMFPELLQSTDSRIADFYKMRHDGVERVAGVEADVVMLVPKDS
EECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
MRFGYRIWTEQKKGLVVKLQTLDADGKVLEQAAFSELQLDAPVKMDQLIQMMGKVDGYRV
CCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEE
EKPVMVKTTASAEGWVLKAPVAGFKPMSCYKRPAANAAPGAEPLQWIFSDGLASVSIFVE
CCCEEEEEECCCCCCEEECCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEEC
PYDRQRHEKESSLSLGATQTLTRQVDAYWVTIMGEVPMATLRHFANGLERKK
CCHHHHHHHHHHCCCCHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412698; 8378309; 8444793; 10984043 [H]