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The map label for this gene is degP [H]

Identifier: 91789490

GI number: 91789490

Start: 3841148

End: 3842611

Strand: Reverse

Name: degP [H]

Synonym: Bpro_3640

Alternate gene names: 91789490

Gene position: 3842611-3841148 (Counterclockwise)

Preceding gene: 91789491

Following gene: 91789489

Centisome position: 73.89

GC content: 60.79

Gene sequence:

>1464_bases
ATGCTTGAATTGAACCGGAAACCCCTGCGCTCCTATTTGCTCGCAGGTCTGTTGGGCGTGGTGACAGCCACCGTGGTGCT
GCCTGTCGCTCCCGCGTGGGCGCAGGTCCGCACGCTGCCTGACTTCACCGATCTGGTTGATCAGGTCGGCCCCTCGGTGG
TGAACATCCGCACGATAGAAAAAGTGAAAGCCTCGGGTGCGGGAAGCGTGGATGAGCAAATGCTGGAGTTTTTCAGGCGT
TTCGGGATTCCCGTACCACCCAACATGCCGCGCGCGCCGCGTCCAGACCGCGGCCAGCCCCAGCCCGACGAAGAGCAGCC
GCGTGGTGTGGGTTCCGGCTTCATCCTCACGGGAGACGGTTTTGTCATGACCAATGCCCATGTGGTGGAGGGCGCCGATG
AAGTGATTGTCACGCTGACTGACAAGCGTGAATTCAAGGCCAAAATCATCGGAGCGGACAAGCGCAGCGATGTGGCGGTC
GTGAAGATAGAGGCAAGCGGGTTGCCGGCCGTGAAAATCGGTGACATCAACCGCCTGAAAGTGGGCGAATGGGTGATGGC
CATCGGCTCACCGTTTGGCCTTGAAAACACCGTGACGGCGGGTATTGTGAGCGCCAAGCAGCGCGATACCGGCGACTACC
TGTCCTTCATCCAGACCGATGTGGCCATCAACCCCGGCAACTCGGGTGGGCCCCTGATCAACATGCGCGGGGAGGTCGTG
GGTATCAACAGCCAGATCTATTCACGTTCTGGCGGCTTTCAGGGCATTTCGTTTTCCATCCCGATTGACGAGGCAACGCG
TGTTTCAGACCAGCTGCGCAGCAGTGGTCGGGTCACACGTGGACGCATCGGGGTGCAGATCGACCAGGTCAGCAAGGAAG
TGGCCGAATCCATCGGTCTGGGCAGTCCCCGCGGGGCGCTGGTCAGAGGCGTGGAGGCTGGTGCACCTGCAGAAAAGGCA
GGCGTAGAAGCCGGCGACATCATCATCAAGTTCGACGGCAAGCAGATCGAAAAATCCAGTGATCTTCCGCGCATGGTCGG
CAATGTGAAGCCCGGCACCAAGGCGGTGGTGACCGTCTTCAGGCGGGGTGCTACCAGGGATTTGCCGGTGGTCATCGCGG
AGGTGGAAGCAGAGAAGCCCCTTCGCAAGGCCTCGTCACCGGAAGCCAAACCGCCGGTCGCCGGCCCTGCACAGGCTTTG
GGCCTGGTGGTGAGCGACCTGCCGGATGCACAGAAAAAGGAACTCAAGATCAAGGGCGGGGTCCGGGTAGACAGCGCCGA
GGGTGGAGCCGCCCGTGCAGGACTTCGCGAGGGTGATGTGATCGTTGCGATTGCCAACTCCGAAATCACAACCGTCAAGG
AGTTCGAGGCTGCGCTCGCAAAAATTGACAAGAGCAAGCCCGTCAATGTGCTGTTTCGCCGGGGAGAACTGGCGCAGTTT
GTGTTGATCCGGCCGGCACGTTGA

Upstream 100 bases:

>100_bases
AGGTGCCGCATATTGCCCGTATTGTTTTTTCTCTGGCGTCCCTATTTCCTTCCCACAAGTTTTGCTTGCCTGATTACCAA
CATTTACGACGAGGCCGATG

Downstream 100 bases:

>100_bases
TGGTTTGAGTTCGTCTGGCGATGAGGGCCTTCTCCACGCTGTGGTTCCTCTCGCTAGGTGCATGAAAGACCCCCATACCC
CGTCCGGGTTGGGGGTTTTT

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MLELNRKPLRSYLLAGLLGVVTATVVLPVAPAWAQVRTLPDFTDLVDQVGPSVVNIRTIEKVKASGAGSVDEQMLEFFRR
FGIPVPPNMPRAPRPDRGQPQPDEEQPRGVGSGFILTGDGFVMTNAHVVEGADEVIVTLTDKREFKAKIIGADKRSDVAV
VKIEASGLPAVKIGDINRLKVGEWVMAIGSPFGLENTVTAGIVSAKQRDTGDYLSFIQTDVAINPGNSGGPLINMRGEVV
GINSQIYSRSGGFQGISFSIPIDEATRVSDQLRSSGRVTRGRIGVQIDQVSKEVAESIGLGSPRGALVRGVEAGAPAEKA
GVEAGDIIIKFDGKQIEKSSDLPRMVGNVKPGTKAVVTVFRRGATRDLPVVIAEVEAEKPLRKASSPEAKPPVAGPAQAL
GLVVSDLPDAQKKELKIKGGVRVDSAEGGAARAGLREGDVIVAIANSEITTVKEFEAALAKIDKSKPVNVLFRRGELAQF
VLIRPAR

Sequences:

>Translated_487_residues
MLELNRKPLRSYLLAGLLGVVTATVVLPVAPAWAQVRTLPDFTDLVDQVGPSVVNIRTIEKVKASGAGSVDEQMLEFFRR
FGIPVPPNMPRAPRPDRGQPQPDEEQPRGVGSGFILTGDGFVMTNAHVVEGADEVIVTLTDKREFKAKIIGADKRSDVAV
VKIEASGLPAVKIGDINRLKVGEWVMAIGSPFGLENTVTAGIVSAKQRDTGDYLSFIQTDVAINPGNSGGPLINMRGEVV
GINSQIYSRSGGFQGISFSIPIDEATRVSDQLRSSGRVTRGRIGVQIDQVSKEVAESIGLGSPRGALVRGVEAGAPAEKA
GVEAGDIIIKFDGKQIEKSSDLPRMVGNVKPGTKAVVTVFRRGATRDLPVVIAEVEAEKPLRKASSPEAKPPVAGPAQAL
GLVVSDLPDAQKKELKIKGGVRVDSAEGGAARAGLREGDVIVAIANSEITTVKEFEAALAKIDKSKPVNVLFRRGELAQF
VLIRPAR
>Mature_487_residues
MLELNRKPLRSYLLAGLLGVVTATVVLPVAPAWAQVRTLPDFTDLVDQVGPSVVNIRTIEKVKASGAGSVDEQMLEFFRR
FGIPVPPNMPRAPRPDRGQPQPDEEQPRGVGSGFILTGDGFVMTNAHVVEGADEVIVTLTDKREFKAKIIGADKRSDVAV
VKIEASGLPAVKIGDINRLKVGEWVMAIGSPFGLENTVTAGIVSAKQRDTGDYLSFIQTDVAINPGNSGGPLINMRGEVV
GINSQIYSRSGGFQGISFSIPIDEATRVSDQLRSSGRVTRGRIGVQIDQVSKEVAESIGLGSPRGALVRGVEAGAPAEKA
GVEAGDIIIKFDGKQIEKSSDLPRMVGNVKPGTKAVVTVFRRGATRDLPVVIAEVEAEKPLRKASSPEAKPPVAGPAQAL
GLVVSDLPDAQKKELKIKGGVRVDSAEGGAARAGLREGDVIVAIANSEITTVKEFEAALAKIDKSKPVNVLFRRGELAQF
VLIRPAR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=266, Percent_Identity=36.4661654135338, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI4506141, Length=351, Percent_Identity=32.7635327635328, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=35.6, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI7019477, Length=263, Percent_Identity=35.361216730038, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1789629, Length=458, Percent_Identity=33.8427947598253, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786356, Length=384, Percent_Identity=35.6770833333333, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1789630, Length=285, Percent_Identity=37.5438596491228, Blast_Score=174, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24646839, Length=256, Percent_Identity=35.15625, Blast_Score=154, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 51599; Mature: 51599

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELNRKPLRSYLLAGLLGVVTATVVLPVAPAWAQVRTLPDFTDLVDQVGPSVVNIRTIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCEEEEEHHH
KVKASGAGSVDEQMLEFFRRFGIPVPPNMPRAPRPDRGQPQPDEEQPRGVGSGFILTGDG
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
FVMTNAHVVEGADEVIVTLTDKREFKAKIIGADKRSDVAVVKIEASGLPAVKIGDINRLK
EEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCEEE
VGEWVMAIGSPFGLENTVTAGIVSAKQRDTGDYLSFIQTDVAINPGNSGGPLINMRGEVV
HHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCEEECCCCCCCCEEEECCCEE
GINSQIYSRSGGFQGISFSIPIDEATRVSDQLRSSGRVTRGRIGVQIDQVSKEVAESIGL
EECHHHECCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEECEECEEHHHHHHHHHHHCCC
GSPRGALVRGVEAGAPAEKAGVEAGDIIIKFDGKQIEKSSDLPRMVGNVKPGTKAVVTVF
CCCCCHHEECCCCCCCHHHHCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHH
RRGATRDLPVVIAEVEAEKPLRKASSPEAKPPVAGPAQALGLVVSDLPDAQKKELKIKGG
HCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHCEEEECC
VRVDSAEGGAARAGLREGDVIVAIANSEITTVKEFEAALAKIDKSKPVNVLFRRGELAQF
EEEECCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEE
VLIRPAR
EEEECCC
>Mature Secondary Structure
MLELNRKPLRSYLLAGLLGVVTATVVLPVAPAWAQVRTLPDFTDLVDQVGPSVVNIRTIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCEEEEEHHH
KVKASGAGSVDEQMLEFFRRFGIPVPPNMPRAPRPDRGQPQPDEEQPRGVGSGFILTGDG
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
FVMTNAHVVEGADEVIVTLTDKREFKAKIIGADKRSDVAVVKIEASGLPAVKIGDINRLK
EEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCEEE
VGEWVMAIGSPFGLENTVTAGIVSAKQRDTGDYLSFIQTDVAINPGNSGGPLINMRGEVV
HHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCEEECCCCCCCCEEEECCCEE
GINSQIYSRSGGFQGISFSIPIDEATRVSDQLRSSGRVTRGRIGVQIDQVSKEVAESIGL
EECHHHECCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEECEECEEHHHHHHHHHHHCCC
GSPRGALVRGVEAGAPAEKAGVEAGDIIIKFDGKQIEKSSDLPRMVGNVKPGTKAVVTVF
CCCCCHHEECCCCCCCHHHHCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHH
RRGATRDLPVVIAEVEAEKPLRKASSPEAKPPVAGPAQALGLVVSDLPDAQKKELKIKGG
HCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHCEEEECC
VRVDSAEGGAARAGLREGDVIVAIANSEITTVKEFEAALAKIDKSKPVNVLFRRGELAQF
EEEECCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEE
VLIRPAR
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]