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The map label for this gene is pucI [H]

Identifier: 91789432

GI number: 91789432

Start: 3779501

End: 3780961

Strand: Direct

Name: pucI [H]

Synonym: Bpro_3578

Alternate gene names: 91789432

Gene position: 3779501-3780961 (Clockwise)

Preceding gene: 91789431

Following gene: 91789433

Centisome position: 72.68

GC content: 62.7

Gene sequence:

>1461_bases
ATGGACATTCGCAACCCATCGCCCGACCTTTACAACGAAGACCTGGCCCCGGCAAAAACGCGGAACTGGGGCACCTTCAG
CATCTTCAATGTGTGGACCTCGGACGTGCACAGCCTCTGGGGTTATTACCTGGCAGCCAGCCTGTTCCTGCTGTGCGGCA
GTTTCACCAACTTTCTGCTGGCCATCGGCCTGAGCTCGATGGTGATCTTTTTCCTGATGAACCTGGTCGGCTATGCCGGC
GTTAAAACCGGCGTTCCCTACCCGGTGCTGGCCCGCGCCTCCTTCGGCGTGTGGGGTGCCAACCTGCCCGCGCTGGTGCG
TGCGGTGGTGGCCTGCTTCTGGTACGGCGCACAAACTGCCGCGGCCTCGGGCGCCATCGTGGCCCTGCTCACCCGCTCCG
ATGCCATCATGGCGTTTCACAAATCAACGCATATGCTGGGCCATTCGGGCCTGGAGGTGATTTGCTTCGTCGTCGTCTGG
GCCTTGCAGCTGCTGATCATCCAGAACGGCATGGAAACCGTGCGCAAGTTCCAGGACTGGGCCGGCCCGGCGGTGTGGGT
GGCCATGCTGGTGCTTGCCGTGGGCCTATGCGTCAAGGCCGGCGGCTTCTCGTTTGACCACGGCATTCCGCAGGATGTGC
TGCTGGCCAAGACCAAGGATGCCGGCGTCCCCGGCGAGCCCGGCTCGTTCTGGGCACTGATGGCCGTGGGCGCCACCTGG
ATCACCTACTTCGCCGCGCTGTACCTGAACTTCTGCGATTTCTCGCGTTATGCCAAAGACAAGGCCACCGTCAAGAAAGG
CAACCTCTGGGGCCTGCCGATCAACCTGATCCTGTTCTCGCTGGTGGCTGGCGTAACGACGATTGCCGCCTTCAAGGTGT
ATGGCGAGGTGCTGCTGCACCCCGAGCAGATTTCCGCCAAGTTCGACAGCTGGTTCCTGGCGCTGCTGGCCGCGCTGACC
TTTGCCGTGGCGACGCTGGGCATCAACGTGGTGGCCAACTTCGTCTCGCCCGCCTTTGACTTTGCCAATGTGTTCCCGCG
CAAGATCAGCTTCAAGACCGGCGGCTACATCGCGGCAGGCATCGCGCTGGTGCTCTACCCGTTTGCGCCCTGGGAAGGCA
ACGCGGCAACGTTTGTCGGCGCCATCGGCGCCACCATGGGGCCGCTGCTGGGCATCATCCTGGTGGACTACTACCTGATC
GCCAAAGGTGAGGTCAACGTGGAAGCGCTCTACCACGAGGACGGCGAATACCGCTACCAGGGCGGCTGGAACCCCAATGC
CCTCATCGCCACCTTCATTGGCGCAATGTTCTCCAGCATATTGCCCAACTTCACCAGCCTGCTGCCGTCCTGGTGGGGCA
TTTATGGCTGGTTCTTTGGCGTGGCCATTGGCGGCATTGCCTATTACGCGCTGGCCATGGCCATGCCCCGGGCGGCGGCT
GCGGCACACGCCAAGGCCTGA

Upstream 100 bases:

>100_bases
CTGAGTACAGTCGTGTATACAAAATTGACCGGCCCGCCGATCAGCCGTTTGTAACCCGTCCCCCTGGCCCTGCATTCACC
CTCTGCATTGGAGATCACCC

Downstream 100 bases:

>100_bases
CACCTCAGCACGGCGGCCTCGGGCGACATCAGCCCACGCATGGCATCTGTATTGCAGGTGGAGACTGGCCGGAATCCCCA
TCAGGAGATGCGTGCCGTAA

Product: cytosine/purines, uracil, thiamine, allantoin permease

Products: NA

Alternate protein names: Allantoin transport protein [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MDIRNPSPDLYNEDLAPAKTRNWGTFSIFNVWTSDVHSLWGYYLAASLFLLCGSFTNFLLAIGLSSMVIFFLMNLVGYAG
VKTGVPYPVLARASFGVWGANLPALVRAVVACFWYGAQTAAASGAIVALLTRSDAIMAFHKSTHMLGHSGLEVICFVVVW
ALQLLIIQNGMETVRKFQDWAGPAVWVAMLVLAVGLCVKAGGFSFDHGIPQDVLLAKTKDAGVPGEPGSFWALMAVGATW
ITYFAALYLNFCDFSRYAKDKATVKKGNLWGLPINLILFSLVAGVTTIAAFKVYGEVLLHPEQISAKFDSWFLALLAALT
FAVATLGINVVANFVSPAFDFANVFPRKISFKTGGYIAAGIALVLYPFAPWEGNAATFVGAIGATMGPLLGIILVDYYLI
AKGEVNVEALYHEDGEYRYQGGWNPNALIATFIGAMFSSILPNFTSLLPSWWGIYGWFFGVAIGGIAYYALAMAMPRAAA
AAHAKA

Sequences:

>Translated_486_residues
MDIRNPSPDLYNEDLAPAKTRNWGTFSIFNVWTSDVHSLWGYYLAASLFLLCGSFTNFLLAIGLSSMVIFFLMNLVGYAG
VKTGVPYPVLARASFGVWGANLPALVRAVVACFWYGAQTAAASGAIVALLTRSDAIMAFHKSTHMLGHSGLEVICFVVVW
ALQLLIIQNGMETVRKFQDWAGPAVWVAMLVLAVGLCVKAGGFSFDHGIPQDVLLAKTKDAGVPGEPGSFWALMAVGATW
ITYFAALYLNFCDFSRYAKDKATVKKGNLWGLPINLILFSLVAGVTTIAAFKVYGEVLLHPEQISAKFDSWFLALLAALT
FAVATLGINVVANFVSPAFDFANVFPRKISFKTGGYIAAGIALVLYPFAPWEGNAATFVGAIGATMGPLLGIILVDYYLI
AKGEVNVEALYHEDGEYRYQGGWNPNALIATFIGAMFSSILPNFTSLLPSWWGIYGWFFGVAIGGIAYYALAMAMPRAAA
AAHAKA
>Mature_486_residues
MDIRNPSPDLYNEDLAPAKTRNWGTFSIFNVWTSDVHSLWGYYLAASLFLLCGSFTNFLLAIGLSSMVIFFLMNLVGYAG
VKTGVPYPVLARASFGVWGANLPALVRAVVACFWYGAQTAAASGAIVALLTRSDAIMAFHKSTHMLGHSGLEVICFVVVW
ALQLLIIQNGMETVRKFQDWAGPAVWVAMLVLAVGLCVKAGGFSFDHGIPQDVLLAKTKDAGVPGEPGSFWALMAVGATW
ITYFAALYLNFCDFSRYAKDKATVKKGNLWGLPINLILFSLVAGVTTIAAFKVYGEVLLHPEQISAKFDSWFLALLAALT
FAVATLGINVVANFVSPAFDFANVFPRKISFKTGGYIAAGIALVLYPFAPWEGNAATFVGAIGATMGPLLGIILVDYYLI
AKGEVNVEALYHEDGEYRYQGGWNPNALIATFIGAMFSSILPNFTSLLPSWWGIYGWFFGVAIGGIAYYALAMAMPRAAA
AAHAKA

Specific function: Transport of allantoin [H]

COG id: COG1953

COG function: function code FH; Cytosine/uracil/thiamine/allantoin permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI87081749, Length=485, Percent_Identity=29.2783505154639, Blast_Score=162, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6319495, Length=459, Percent_Identity=23.5294117647059, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322219, Length=424, Percent_Identity=24.2924528301887, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6319429, Length=464, Percent_Identity=23.9224137931034, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323266, Length=445, Percent_Identity=22.0224719101124, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324645, Length=443, Percent_Identity=22.1218961625282, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324766, Length=439, Percent_Identity=21.4123006833713, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 52378; Mature: 52378

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRNPSPDLYNEDLAPAKTRNWGTFSIFNVWTSDVHSLWGYYLAASLFLLCGSFTNFLL
CCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGLSSMVIFFLMNLVGYAGVKTGVPYPVLARASFGVWGANLPALVRAVVACFWYGAQTA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHH
AASGAIVALLTRSDAIMAFHKSTHMLGHSGLEVICFVVVWALQLLIIQNGMETVRKFQDW
HCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AGPAVWVAMLVLAVGLCVKAGGFSFDHGIPQDVLLAKTKDAGVPGEPGSFWALMAVGATW
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCCCCCCCCCHHHHHHHHHHH
ITYFAALYLNFCDFSRYAKDKATVKKGNLWGLPINLILFSLVAGVTTIAAFKVYGEVLLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEQISAKFDSWFLALLAALTFAVATLGINVVANFVSPAFDFANVFPRKISFKTGGYIAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHH
IALVLYPFAPWEGNAATFVGAIGATMGPLLGIILVDYYLIAKGEVNVEALYHEDGEYRYQ
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEC
GGWNPNALIATFIGAMFSSILPNFTSLLPSWWGIYGWFFGVAIGGIAYYALAMAMPRAAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHAKA
HHCCCC
>Mature Secondary Structure
MDIRNPSPDLYNEDLAPAKTRNWGTFSIFNVWTSDVHSLWGYYLAASLFLLCGSFTNFLL
CCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGLSSMVIFFLMNLVGYAGVKTGVPYPVLARASFGVWGANLPALVRAVVACFWYGAQTA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHH
AASGAIVALLTRSDAIMAFHKSTHMLGHSGLEVICFVVVWALQLLIIQNGMETVRKFQDW
HCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AGPAVWVAMLVLAVGLCVKAGGFSFDHGIPQDVLLAKTKDAGVPGEPGSFWALMAVGATW
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCCCCCCCCCHHHHHHHHHHH
ITYFAALYLNFCDFSRYAKDKATVKKGNLWGLPINLILFSLVAGVTTIAAFKVYGEVLLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEQISAKFDSWFLALLAALTFAVATLGINVVANFVSPAFDFANVFPRKISFKTGGYIAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHH
IALVLYPFAPWEGNAATFVGAIGATMGPLLGIILVDYYLIAKGEVNVEALYHEDGEYRYQ
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEC
GGWNPNALIATFIGAMFSSILPNFTSLLPSWWGIYGWFFGVAIGGIAYYALAMAMPRAAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHAKA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 11344136 [H]