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The map label for this gene is garD [H]

Identifier: 91789430

GI number: 91789430

Start: 3776658

End: 3778190

Strand: Direct

Name: garD [H]

Synonym: Bpro_3576

Alternate gene names: 91789430

Gene position: 3776658-3778190 (Clockwise)

Preceding gene: 91789429

Following gene: 91789431

Centisome position: 72.62

GC content: 66.08

Gene sequence:

>1533_bases
ATGCCTTCCCCCACCGCCAGTCCGCTGATCCGCCTGCACGCCAACGACAACGTGCTGGTGGCGAAGACCCCGCTCGCACT
GGGCCAGGCGCTGCCGGAGATTGATGCGCGTGCGCGCGCCCAGGTGCCGGCCGGTCACAAGATCGCCGCCTGCCGCATCG
CCGGGGGCGAGCGCATCATCAAGTACGACACCGTGATCGGCATCGCCGCGCGCGACATCGAGGCGGGCGACCATGTGCAC
GCGCACAACCTGACGCTGGTGAACTTCGAGCGTGACCCGGCTTTCGGCCAGGACGTGCGGCCAGTCGAGTATGTGACGGA
TGCCGAGCGCGCCACCTTCATGGGTTTTGTGCGCCCCGACGGCCGCGTCGGCACCCGCAACTTCATCGGCATTCTGTCGT
CGGTCAACTGCTCCGCCACCGTCATCAAGAACATTGCGGCCCACTTCACGCCAGAGCGGCTGGCGGACTTTCCACACGTG
GACGGCGTGGCCGCCTTTGCGCAAACCAGCGGCTGCGGCATGTCGTCGCCCAGCGAACATTTTGATGTGCTGCGCCGCAC
GTTGGCCGGCTATGCCCGCCATCCCAACCTGGCAGGGGTGCTGATTGTGGGGCTGGGCTGCGAGCGCAACCAGGTGGCGT
CGCTGGTGGAATCGCAAGGCCTGCCTGAAAGCAAACTCATGCGCACGCTGGTAATGCAGGAGGTGGGCGGCACCCGCGTA
ACCATTGAAGCCGGCATAGCCGCCATCCGGGAGATGCTGCCTGAAGCGAATGCCGCCCGGCGTCAGCCCGTGCCGGCCAG
CCATTTGAAGATTGGCCTGGAGTGCGGCGGCTCCGACGGCTTCTCCGGCATCACGGCCAATCCGGCGCTGGGCGCGGCCA
TGGACATTCTGGTGCGCCACGGCGGCACCGCCATCCTGTCGGAAACGCCCGAGATCCATGGTGTGGAATACATGCTGACC
CGCCGCGCCGTGACCCCGGAAGTCGGCCAGAAACTGCTGGACCGGCTGGCCTGGTGGGAGCACTACACGGCGGGCCACAA
CGCCCAGTTCAATGGCGTGGTCGGGCACGGCAACCAGGCGGGCGGGCTGGCCAATATCTTTGAAAAATCGCTGGGCTCGG
CCATGAAGGGCGGCACCACGCCGCTGCAGGCCGTGTATGAATACGCCGAGCCCATCGACCGCCACGGTTTCGTGTTCATG
GATTCGCCGGGCTACGACCCGGTGGCCTCGACCGGGCAAATTGCCAGCGGCGCCAACCTGATTTGTTTTACCACTGGCCG
CGGCTCGATGTTCGGCTCCAAGCCGGCGCCCACGATCAAGCTGGCCAGCAACACGCCCATGTTCACCCGCCTGGAGGAAG
ACATGGACCTCAATTGCGGCGCCATCCTGGACGGCAAGCTGGACGTGCCGCAAATGGGCCAGCGGATTTTCGAGGCCATC
CTGCGCCATGCCTCGGGCGAGCCGACCAAAAGCGAGGCACTGGGCCTGGGCGATCACGAATTCGTGCCCTGGCACCTGGG
CATTGTGAGCTGA

Upstream 100 bases:

>100_bases
TCAAGCTCAGGGAATTGATGAAGAGCTGAGCGCCACCCGCGTTGCCTTTCCCAACTCAGCCCACCCCTTCCAGACCTTTC
CAGACCTTCCCAGTCCAGCC

Downstream 100 bases:

>100_bases
CCGCCGCGCCCCTAAGGCTGCCCCAAGACTGCCCTGAGACTGGTATCGTCGGCATTCGCGACAGCACGCTTTGGACAAGG
GACACGAGGGATCGCGTCGC

Product: Altronate dehydratase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MPSPTASPLIRLHANDNVLVAKTPLALGQALPEIDARARAQVPAGHKIAACRIAGGERIIKYDTVIGIAARDIEAGDHVH
AHNLTLVNFERDPAFGQDVRPVEYVTDAERATFMGFVRPDGRVGTRNFIGILSSVNCSATVIKNIAAHFTPERLADFPHV
DGVAAFAQTSGCGMSSPSEHFDVLRRTLAGYARHPNLAGVLIVGLGCERNQVASLVESQGLPESKLMRTLVMQEVGGTRV
TIEAGIAAIREMLPEANAARRQPVPASHLKIGLECGGSDGFSGITANPALGAAMDILVRHGGTAILSETPEIHGVEYMLT
RRAVTPEVGQKLLDRLAWWEHYTAGHNAQFNGVVGHGNQAGGLANIFEKSLGSAMKGGTTPLQAVYEYAEPIDRHGFVFM
DSPGYDPVASTGQIASGANLICFTTGRGSMFGSKPAPTIKLASNTPMFTRLEEDMDLNCGAILDGKLDVPQMGQRIFEAI
LRHASGEPTKSEALGLGDHEFVPWHLGIVS

Sequences:

>Translated_510_residues
MPSPTASPLIRLHANDNVLVAKTPLALGQALPEIDARARAQVPAGHKIAACRIAGGERIIKYDTVIGIAARDIEAGDHVH
AHNLTLVNFERDPAFGQDVRPVEYVTDAERATFMGFVRPDGRVGTRNFIGILSSVNCSATVIKNIAAHFTPERLADFPHV
DGVAAFAQTSGCGMSSPSEHFDVLRRTLAGYARHPNLAGVLIVGLGCERNQVASLVESQGLPESKLMRTLVMQEVGGTRV
TIEAGIAAIREMLPEANAARRQPVPASHLKIGLECGGSDGFSGITANPALGAAMDILVRHGGTAILSETPEIHGVEYMLT
RRAVTPEVGQKLLDRLAWWEHYTAGHNAQFNGVVGHGNQAGGLANIFEKSLGSAMKGGTTPLQAVYEYAEPIDRHGFVFM
DSPGYDPVASTGQIASGANLICFTTGRGSMFGSKPAPTIKLASNTPMFTRLEEDMDLNCGAILDGKLDVPQMGQRIFEAI
LRHASGEPTKSEALGLGDHEFVPWHLGIVS
>Mature_509_residues
PSPTASPLIRLHANDNVLVAKTPLALGQALPEIDARARAQVPAGHKIAACRIAGGERIIKYDTVIGIAARDIEAGDHVHA
HNLTLVNFERDPAFGQDVRPVEYVTDAERATFMGFVRPDGRVGTRNFIGILSSVNCSATVIKNIAAHFTPERLADFPHVD
GVAAFAQTSGCGMSSPSEHFDVLRRTLAGYARHPNLAGVLIVGLGCERNQVASLVESQGLPESKLMRTLVMQEVGGTRVT
IEAGIAAIREMLPEANAARRQPVPASHLKIGLECGGSDGFSGITANPALGAAMDILVRHGGTAILSETPEIHGVEYMLTR
RAVTPEVGQKLLDRLAWWEHYTAGHNAQFNGVVGHGNQAGGLANIFEKSLGSAMKGGTTPLQAVYEYAEPIDRHGFVFMD
SPGYDPVASTGQIASGANLICFTTGRGSMFGSKPAPTIKLASNTPMFTRLEEDMDLNCGAILDGKLDVPQMGQRIFEAIL
RHASGEPTKSEALGLGDHEFVPWHLGIVS

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=503, Percent_Identity=34.7912524850895, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1789475, Length=491, Percent_Identity=35.030549898167, Blast_Score=262, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 54277; Mature: 54145

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPTASPLIRLHANDNVLVAKTPLALGQALPEIDARARAQVPAGHKIAACRIAGGERII
CCCCCCCCEEEEECCCCEEEEECCHHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCCEEE
KYDTVIGIAARDIEAGDHVHAHNLTLVNFERDPAFGQDVRPVEYVTDAERATFMGFVRPD
EEEEEEEEEEECCCCCCCEEECCEEEEEECCCCCCCCCCCCHHHHHCCCHHEEEEEECCC
GRVGTRNFIGILSSVNCSATVIKNIAAHFTPERLADFPHVDGVAAFAQTSGCGMSSPSEH
CCCCCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHCCCCCCCCCHHH
FDVLRRTLAGYARHPNLAGVLIVGLGCERNQVASLVESQGLPESKLMRTLVMQEVGGTRV
HHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
TIEAGIAAIREMLPEANAARRQPVPASHLKIGLECGGSDGFSGITANPALGAAMDILVRH
EHHHHHHHHHHHCCCCCHHHCCCCCHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
GGTAILSETPEIHGVEYMLTRRAVTPEVGQKLLDRLAWWEHYTAGHNAQFNGVVGHGNQA
CCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCEEECCCCC
GGLANIFEKSLGSAMKGGTTPLQAVYEYAEPIDRHGFVFMDSPGYDPVASTGQIASGANL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCE
ICFTTGRGSMFGSKPAPTIKLASNTPMFTRLEEDMDLNCGAILDGKLDVPQMGQRIFEAI
EEEECCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHH
LRHASGEPTKSEALGLGDHEFVPWHLGIVS
HHHCCCCCCHHHHCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
PSPTASPLIRLHANDNVLVAKTPLALGQALPEIDARARAQVPAGHKIAACRIAGGERII
CCCCCCCEEEEECCCCEEEEECCHHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCCEEE
KYDTVIGIAARDIEAGDHVHAHNLTLVNFERDPAFGQDVRPVEYVTDAERATFMGFVRPD
EEEEEEEEEEECCCCCCCEEECCEEEEEECCCCCCCCCCCCHHHHHCCCHHEEEEEECCC
GRVGTRNFIGILSSVNCSATVIKNIAAHFTPERLADFPHVDGVAAFAQTSGCGMSSPSEH
CCCCCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHCCCCCCCCCHHH
FDVLRRTLAGYARHPNLAGVLIVGLGCERNQVASLVESQGLPESKLMRTLVMQEVGGTRV
HHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
TIEAGIAAIREMLPEANAARRQPVPASHLKIGLECGGSDGFSGITANPALGAAMDILVRH
EHHHHHHHHHHHCCCCCHHHCCCCCHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
GGTAILSETPEIHGVEYMLTRRAVTPEVGQKLLDRLAWWEHYTAGHNAQFNGVVGHGNQA
CCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCEEECCCCC
GGLANIFEKSLGSAMKGGTTPLQAVYEYAEPIDRHGFVFMDSPGYDPVASTGQIASGANL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCE
ICFTTGRGSMFGSKPAPTIKLASNTPMFTRLEEDMDLNCGAILDGKLDVPQMGQRIFEAI
EEEECCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHH
LRHASGEPTKSEALGLGDHEFVPWHLGIVS
HHHCCCCCCHHHHCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 2407727; 9772162; 10762278 [H]