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The map label for this gene is argF [H]

Identifier: 91789427

GI number: 91789427

Start: 3773127

End: 3774116

Strand: Direct

Name: argF [H]

Synonym: Bpro_3573

Alternate gene names: 91789427

Gene position: 3773127-3774116 (Clockwise)

Preceding gene: 91789426

Following gene: 91789429

Centisome position: 72.56

GC content: 62.22

Gene sequence:

>990_bases
ATGACCAAGAGCGCGACCAAGGCAACGAAATCCGGGGCCGGCGAATCAGCCGAAGCGAAAAGCACCGCGGCCAGGCCCAT
CAGACACTACCTGCAGTTCAGCGACCTGAATGCCAGCGAATACGCCTACCTGTTCGAACGGGCGGCGGTCATCAAGAAAA
AATTCAAGGCCTACGAAAAGCACCAGCCGCTGGCGGACCGCACGCTGGCAATGATTTTCGAAAAAGCCTCGACCCGCACC
CGCGTCAGCTTTGAGGCCGGCATGTACCAGCTCGGTGGCAGCGTGGTGCACCTCACCACCGGCGACAGCCAGTTGGGCCG
CGCCGAGCCGATTGAAGACAGCGCCAAGGTCATCAGCCGCATGGTCGACCTGGTGATGATCCGCACCTTCGAGCAGACCA
AGATCGACCGCTTTGCCGAGCATTCGCGCGTGCCGGTCATCAACGGCCTGACCAACGAATTCCACCCCTGCCAGATCCTG
GCGGACATCTTCACCTACATCGAGCACCGCGGCTCCATCCTGGGCAAGACTGTGGCCTGGGTGGGCGACGGCAACAACAT
GGCCAACACCTGGCTGCAGGCCAGCGAAATCCTGGGCTTCAAGGTGCATGTGAGCACACCTGGCGGCTATGAGGTCGACC
AGTCCATTGCCGGTATCCGCTCGGCCGAAAGCTACCAGGTGTTCAAGGACCCGATGCAGGCCTGCGCCGGCGCCGACCTG
GTCACCACCGATGTGTGGACCAGCATGGGCTATGAAGCCGAAAACGAAGCGCGCAAGAAAGCCTTTGCCGACTGGTGCGT
CGATGCCGACATGATGCGGGCCGCCAAGCCCGATGCCCTGTTCATGCACTGCCTGCCCGCGCACCGCGGCGAAGAGGTCG
AAGCCGACGTGATTGACGGGCCGCAGTCCGTGGTGTGGGACGAGGCGGAAAACAGGATGCACGTGCAGAAGGCACTCATG
GAGTTCCTGCTGCTCGGACGGGTCGAATGA

Upstream 100 bases:

>100_bases
TGATCCGCCTGGTGCCGTCGCTGATCATGACCACCGCCGAAGCCGATGAAGTCGTGGCGATTGTGGTCCCGCTGATCAAG
CAGTTATTGAAAGAGAAAGC

Downstream 100 bases:

>100_bases
AATTCGGCCCGGTGGCGCATTAGTGCATTAGCGCCGGCATTCTGTTTCGGCACAGGCTCATGTGCGCGCAGCGCACGTTA
GCTCTAGGTGACGACGGCCA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTKSATKATKSGAGESAEAKSTAARPIRHYLQFSDLNASEYAYLFERAAVIKKKFKAYEKHQPLADRTLAMIFEKASTRT
RVSFEAGMYQLGGSVVHLTTGDSQLGRAEPIEDSAKVISRMVDLVMIRTFEQTKIDRFAEHSRVPVINGLTNEFHPCQIL
ADIFTYIEHRGSILGKTVAWVGDGNNMANTWLQASEILGFKVHVSTPGGYEVDQSIAGIRSAESYQVFKDPMQACAGADL
VTTDVWTSMGYEAENEARKKAFADWCVDADMMRAAKPDALFMHCLPAHRGEEVEADVIDGPQSVVWDEAENRMHVQKALM
EFLLLGRVE

Sequences:

>Translated_329_residues
MTKSATKATKSGAGESAEAKSTAARPIRHYLQFSDLNASEYAYLFERAAVIKKKFKAYEKHQPLADRTLAMIFEKASTRT
RVSFEAGMYQLGGSVVHLTTGDSQLGRAEPIEDSAKVISRMVDLVMIRTFEQTKIDRFAEHSRVPVINGLTNEFHPCQIL
ADIFTYIEHRGSILGKTVAWVGDGNNMANTWLQASEILGFKVHVSTPGGYEVDQSIAGIRSAESYQVFKDPMQACAGADL
VTTDVWTSMGYEAENEARKKAFADWCVDADMMRAAKPDALFMHCLPAHRGEEVEADVIDGPQSVVWDEAENRMHVQKALM
EFLLLGRVE
>Mature_328_residues
TKSATKATKSGAGESAEAKSTAARPIRHYLQFSDLNASEYAYLFERAAVIKKKFKAYEKHQPLADRTLAMIFEKASTRTR
VSFEAGMYQLGGSVVHLTTGDSQLGRAEPIEDSAKVISRMVDLVMIRTFEQTKIDRFAEHSRVPVINGLTNEFHPCQILA
DIFTYIEHRGSILGKTVAWVGDGNNMANTWLQASEILGFKVHVSTPGGYEVDQSIAGIRSAESYQVFKDPMQACAGADLV
TTDVWTSMGYEAENEARKKAFADWCVDADMMRAAKPDALFMHCLPAHRGEEVEADVIDGPQSVVWDEAENRMHVQKALME
FLLLGRVE

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=306, Percent_Identity=38.562091503268, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI18105007, Length=307, Percent_Identity=28.0130293159609, Blast_Score=101, Evalue=9e-22,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=36, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=36, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI2367364, Length=312, Percent_Identity=27.2435897435897, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193204318, Length=326, Percent_Identity=27.3006134969325, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6322373, Length=317, Percent_Identity=35.6466876971609, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6322331, Length=306, Percent_Identity=24.8366013071895, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24642586, Length=323, Percent_Identity=27.2445820433437, Blast_Score=104, Evalue=7e-23,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 36537; Mature: 36406

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSATKATKSGAGESAEAKSTAARPIRHYLQFSDLNASEYAYLFERAAVIKKKFKAYEK
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
HQPLADRTLAMIFEKASTRTRVSFEAGMYQLGGSVVHLTTGDSQLGRAEPIEDSAKVISR
CCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHH
MVDLVMIRTFEQTKIDRFAEHSRVPVINGLTNEFHPCQILADIFTYIEHRGSILGKTVAW
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCHHHCEEEE
VGDGNNMANTWLQASEILGFKVHVSTPGGYEVDQSIAGIRSAESYQVFKDPMQACAGADL
EECCCCHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCH
VTTDVWTSMGYEAENEARKKAFADWCVDADMMRAAKPDALFMHCLPAHRGEEVEADVIDG
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHCCCCCCCCCHHHCCC
PQSVVWDEAENRMHVQKALMEFLLLGRVE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKSATKATKSGAGESAEAKSTAARPIRHYLQFSDLNASEYAYLFERAAVIKKKFKAYEK
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
HQPLADRTLAMIFEKASTRTRVSFEAGMYQLGGSVVHLTTGDSQLGRAEPIEDSAKVISR
CCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHH
MVDLVMIRTFEQTKIDRFAEHSRVPVINGLTNEFHPCQILADIFTYIEHRGSILGKTVAW
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCHHHCEEEE
VGDGNNMANTWLQASEILGFKVHVSTPGGYEVDQSIAGIRSAESYQVFKDPMQACAGADL
EECCCCHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCH
VTTDVWTSMGYEAENEARKKAFADWCVDADMMRAAKPDALFMHCLPAHRGEEVEADVIDG
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHCCCCCCCCCHHHCCC
PQSVVWDEAENRMHVQKALMEFLLLGRVE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA