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The map label for this gene is argD1 [H]

Identifier: 91789426

GI number: 91789426

Start: 3771916

End: 3773130

Strand: Direct

Name: argD1 [H]

Synonym: Bpro_3572

Alternate gene names: 91789426

Gene position: 3771916-3773130 (Clockwise)

Preceding gene: 91789424

Following gene: 91789427

Centisome position: 72.53

GC content: 64.2

Gene sequence:

>1215_bases
ATGAACGCAGCCCTGCCCCAGCCCATCGAAGCCGCCTCACCCCACGTCATGAACACCTATGGCCGCCTGCCCATCGCGTT
GTCGCATGGCCAAGGTTGCCGCGTCTGGGACGTCAACGGCAAGTCCTACCTGGACGCGCTGGGCGGTATTGCCGTGAACA
CCGTCGGCCACAACCACCCGAAACTGGTGCCCGCGCTGCAGGAGCAGATCGGCCGGCTGATCCATACCTCCAACTACTAC
CATGTGCCGCTGCAGGAAACGCTGGCGGCCAAACTGGTGGAGCTGTCGGGCCTGGAGAACGTATTTTTCTGCTCCACCGG
CCTTGAAGCCAACGAGGCCGCGTTGAAACTGGCGCGCAAGTTCGGCCATGACAAGGGCATCGAGAGGCCGGAGATCGTGG
TCTATGAAAAAGCCTTCCATGGCCGCAGCATCGCCACCCTGAGCGCCACCGGCAACCCCAAGGTGCAAGCCGGCTTTGGC
CCGCTGGTCGAAGGTTTCATCCGTGTGCCGCTCAACGACCTGGAGGCCCTGAAGGCCGCCACGGTCGGCAACCCCAACGT
GGTCGCCGTGTTCTTTGAAGCCATCCAGGGGGAAGGCGGCATCAACAGTATGAAGGACGAGTACCTGCGGGAGGTGCGCG
CCCTCTGCGACGAGCGCGACTGGCTGCTCATGATCGACGAAGTGCAGTGCGGCATGGGCCGTACCGGCAAATGGTTTGCC
CACCAGTGGTCCGGTATCAAGCCCGATGTCATGCCGCTGGCCAAGGGGCTGGGATCGGGCGTGCCGATCGGCGCGGTGGT
GGCCGGCCCCAAGGCTGCCCATATTTTTAGCCCCGGCAACCACGGCTCGACCTTTGGCGGCAATCCGCTGGCCATGCGCG
CCGGCGTGGAAACCCTGCGCATCATGGAAGAAGAAGGCCTGCTGGCCAATGCGGTCAAGGTGGGCGACCACCTGCGGGCG
GCGCTGACGCGCGAGCTGGCCGACGAGCCGGGCTTGAAGGAAATCCGCGGCCGCGGCCTGATGCTGGGCATTGAGCTGAC
CAAGCCTTGCGGGGAACTGCTTGCCCGCGCTGCCGAGAAAGGCCTGCTGCTGAGCGTGACGGCCGACACCGTGATCCGCC
TGGTGCCGTCGCTGATCATGACCACCGCCGAAGCCGATGAAGTCGTGGCGATTGTGGTCCCGCTGATCAAGCAGTTATTG
AAAGAGAAAGCATGA

Upstream 100 bases:

>100_bases
CTATCGTCACAAAAGCCCGCAAAGTCTGCGCCTAAAATTGCCGCATGCCCGTCGGCTTCCCGGCGGCCGCCTGTTCCCTG
CCTTGCCCGGAGTTTTTGCC

Downstream 100 bases:

>100_bases
CCAAGAGCGCGACCAAGGCAACGAAATCCGGGGCCGGCGAATCAGCCGAAGCGAAAAGCACCGCGGCCAGGCCCATCAGA
CACTACCTGCAGTTCAGCGA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT 1 [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNAALPQPIEAASPHVMNTYGRLPIALSHGQGCRVWDVNGKSYLDALGGIAVNTVGHNHPKLVPALQEQIGRLIHTSNYY
HVPLQETLAAKLVELSGLENVFFCSTGLEANEAALKLARKFGHDKGIERPEIVVYEKAFHGRSIATLSATGNPKVQAGFG
PLVEGFIRVPLNDLEALKAATVGNPNVVAVFFEAIQGEGGINSMKDEYLREVRALCDERDWLLMIDEVQCGMGRTGKWFA
HQWSGIKPDVMPLAKGLGSGVPIGAVVAGPKAAHIFSPGNHGSTFGGNPLAMRAGVETLRIMEEEGLLANAVKVGDHLRA
ALTRELADEPGLKEIRGRGLMLGIELTKPCGELLARAAEKGLLLSVTADTVIRLVPSLIMTTAEADEVVAIVVPLIKQLL
KEKA

Sequences:

>Translated_404_residues
MNAALPQPIEAASPHVMNTYGRLPIALSHGQGCRVWDVNGKSYLDALGGIAVNTVGHNHPKLVPALQEQIGRLIHTSNYY
HVPLQETLAAKLVELSGLENVFFCSTGLEANEAALKLARKFGHDKGIERPEIVVYEKAFHGRSIATLSATGNPKVQAGFG
PLVEGFIRVPLNDLEALKAATVGNPNVVAVFFEAIQGEGGINSMKDEYLREVRALCDERDWLLMIDEVQCGMGRTGKWFA
HQWSGIKPDVMPLAKGLGSGVPIGAVVAGPKAAHIFSPGNHGSTFGGNPLAMRAGVETLRIMEEEGLLANAVKVGDHLRA
ALTRELADEPGLKEIRGRGLMLGIELTKPCGELLARAAEKGLLLSVTADTVIRLVPSLIMTTAEADEVVAIVVPLIKQLL
KEKA
>Mature_404_residues
MNAALPQPIEAASPHVMNTYGRLPIALSHGQGCRVWDVNGKSYLDALGGIAVNTVGHNHPKLVPALQEQIGRLIHTSNYY
HVPLQETLAAKLVELSGLENVFFCSTGLEANEAALKLARKFGHDKGIERPEIVVYEKAFHGRSIATLSATGNPKVQAGFG
PLVEGFIRVPLNDLEALKAATVGNPNVVAVFFEAIQGEGGINSMKDEYLREVRALCDERDWLLMIDEVQCGMGRTGKWFA
HQWSGIKPDVMPLAKGLGSGVPIGAVVAGPKAAHIFSPGNHGSTFGGNPLAMRAGVETLRIMEEEGLLANAVKVGDHLRA
ALTRELADEPGLKEIRGRGLMLGIELTKPCGELLARAAEKGLLLSVTADTVIRLVPSLIMTTAEADEVVAIVVPLIKQLL
KEKA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=36.5535248041775, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI284507298, Length=296, Percent_Identity=37.8378378378378, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI13994255, Length=450, Percent_Identity=30.2222222222222, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI37574042, Length=412, Percent_Identity=28.8834951456311, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=28.4313725490196, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=28.1553398058252, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=28.3464566929134, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI188536080, Length=423, Percent_Identity=25.0591016548463, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679950, Length=423, Percent_Identity=25.0591016548463, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679946, Length=423, Percent_Identity=25.0591016548463, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1789759, Length=368, Percent_Identity=42.1195652173913, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=37.8865979381443, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI145693181, Length=369, Percent_Identity=38.2113821138211, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789016, Length=402, Percent_Identity=33.3333333333333, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787560, Length=386, Percent_Identity=34.9740932642487, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1786991, Length=377, Percent_Identity=28.9124668435013, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786349, Length=347, Percent_Identity=29.6829971181556, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=37.3401534526854, Blast_Score=251, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI32564660, Length=457, Percent_Identity=31.2910284463895, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=274, Percent_Identity=36.1313868613139, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=372, Percent_Identity=29.5698924731183, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71981843, Length=161, Percent_Identity=42.8571428571429, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=462, Percent_Identity=24.025974025974, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=378, Percent_Identity=37.3015873015873, Blast_Score=245, Evalue=9e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=416, Percent_Identity=34.1346153846154, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6321456, Length=425, Percent_Identity=25.6470588235294, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324386, Length=354, Percent_Identity=26.5536723163842, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357415, Length=381, Percent_Identity=36.4829396325459, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI28574759, Length=447, Percent_Identity=29.082774049217, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI161085790, Length=377, Percent_Identity=30.7692307692308, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21356575, Length=428, Percent_Identity=28.0373831775701, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281366494, Length=414, Percent_Identity=25.8454106280193, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24667139, Length=414, Percent_Identity=25.8454106280193, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24667143, Length=414, Percent_Identity=25.8454106280193, Blast_Score=99, Evalue=7e-21,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43205; Mature: 43205

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAALPQPIEAASPHVMNTYGRLPIALSHGQGCRVWDVNGKSYLDALGGIAVNTVGHNHP
CCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEEEECCCHHHHHHHCCEEEECCCCCCC
KLVPALQEQIGRLIHTSNYYHVPLQETLAAKLVELSGLENVFFCSTGLEANEAALKLARK
CHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
FGHDKGIERPEIVVYEKAFHGRSIATLSATGNPKVQAGFGPLVEGFIRVPLNDLEALKAA
HCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCEECCCCHHHHHHHHCCCHHHHHHHHH
TVGNPNVVAVFFEAIQGEGGINSMKDEYLREVRALCDERDWLLMIDEVQCGMGRTGKWFA
CCCCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHH
HQWSGIKPDVMPLAKGLGSGVPIGAVVAGPKAAHIFSPGNHGSTFGGNPLAMRAGVETLR
HHCCCCCCHHHHHHHHCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCEEHHHCHHHHH
IMEEEGLLANAVKVGDHLRAALTRELADEPGLKEIRGRGLMLGIELTKPCGELLARAAEK
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCHHHHHHHHHHHC
GLLLSVTADTVIRLVPSLIMTTAEADEVVAIVVPLIKQLLKEKA
CEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAALPQPIEAASPHVMNTYGRLPIALSHGQGCRVWDVNGKSYLDALGGIAVNTVGHNHP
CCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEEEECCCHHHHHHHCCEEEECCCCCCC
KLVPALQEQIGRLIHTSNYYHVPLQETLAAKLVELSGLENVFFCSTGLEANEAALKLARK
CHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
FGHDKGIERPEIVVYEKAFHGRSIATLSATGNPKVQAGFGPLVEGFIRVPLNDLEALKAA
HCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCEECCCCHHHHHHHHCCCHHHHHHHHH
TVGNPNVVAVFFEAIQGEGGINSMKDEYLREVRALCDERDWLLMIDEVQCGMGRTGKWFA
CCCCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHH
HQWSGIKPDVMPLAKGLGSGVPIGAVVAGPKAAHIFSPGNHGSTFGGNPLAMRAGVETLR
HHCCCCCCHHHHHHHHCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCEEHHHCHHHHH
IMEEEGLLANAVKVGDHLRAALTRELADEPGLKEIRGRGLMLGIELTKPCGELLARAAEK
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCHHHHHHHHHHHC
GLLLSVTADTVIRLVPSLIMTTAEADEVVAIVVPLIKQLLKEKA
CEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]