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The map label for this gene is dgoR [H]

Identifier: 91789384

GI number: 91789384

Start: 3732879

End: 3733622

Strand: Reverse

Name: dgoR [H]

Synonym: Bpro_3530

Alternate gene names: 91789384

Gene position: 3733622-3732879 (Counterclockwise)

Preceding gene: 91789385

Following gene: 91789383

Centisome position: 71.8

GC content: 66.4

Gene sequence:

>744_bases
ATGATCAAAAACGTCCACGGCAACACGGTAGACCTGCTAGGCGAAGCCATCGTCGCGGGCCGCTATGCGGTCGGCCAGTC
GATCCCGCCCGAGCCGGTGTTGTGCGAGCAGCTCGGTGTCAGCCGCACGGTGGTGCGCGAGTCCGTCAAGTCGCTGGTGG
CCAAGGGGCTGATCCATACCGGCCCCAAAGTCGGCACGCATGTGTTGCCGTCCGATCAGTGGAACTGGTTCGACCCTGAC
GTGATTGCCTGGCAGTCGCGCGCTGGCCTGTCACCCGAGTTCATCCGCGACCTGCAGGACCTGCGCCTGGTGGTTGAGCC
GGCGGCCGTGAAGCTGGCGGCGACCCGCGCTACCGATGCCGACATTGCTGAAATCGAAGAGGCCTATGCCGGCATGCATC
GCGCCGTGATGGGCGGCGGCGACTATGTGACCAGCGACCTGCGTTTTCACCAGGGGCTGTTGCGCGCCTCGCACAACCGC
ATGCTGGTGCAGATGAGCAAGGCGCTGGGCGCGCTGCTGCGCACCAGTTTCGAAATCTCCACGAGCAAGAAGGACGGTCC
GCGCAGCTCGCTGCCCTTGCACCGTGCCGTGCTCGATGCCGTGGTGGCGCGCGATCCGGTCAAGGCCGAGCGCGCCGTGC
TGGTGTTGATCGAAGGGGCGCACAAGGACATCGAGCAGGTGCTCGGTTCCCGCCGCCGCCTGCCCCGCGTCCACCGACCT
GCTTTGCCGTTGAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCTGACGCCAGTACCCGAATGCCAGTAAAAGCTCGGGGTTTTCCATAGGTTTTCGGGGCTCTAATCATCATATGATAGCA
ACGCAATTGACTCCCCGAAC

Downstream 100 bases:

>100_bases
TTCCCGTAAGCTTTTCCTCACCAACCAAAGAAGGAGACTGTCGATGAAGTTCAAACTACTTGCCACAGCGGCGTTCATGA
CCACGGCGCTTTTAGCCGGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MIKNVHGNTVDLLGEAIVAGRYAVGQSIPPEPVLCEQLGVSRTVVRESVKSLVAKGLIHTGPKVGTHVLPSDQWNWFDPD
VIAWQSRAGLSPEFIRDLQDLRLVVEPAAVKLAATRATDADIAEIEEAYAGMHRAVMGGGDYVTSDLRFHQGLLRASHNR
MLVQMSKALGALLRTSFEISTSKKDGPRSSLPLHRAVLDAVVARDPVKAERAVLVLIEGAHKDIEQVLGSRRRLPRVHRP
ALPLKAA

Sequences:

>Translated_247_residues
MIKNVHGNTVDLLGEAIVAGRYAVGQSIPPEPVLCEQLGVSRTVVRESVKSLVAKGLIHTGPKVGTHVLPSDQWNWFDPD
VIAWQSRAGLSPEFIRDLQDLRLVVEPAAVKLAATRATDADIAEIEEAYAGMHRAVMGGGDYVTSDLRFHQGLLRASHNR
MLVQMSKALGALLRTSFEISTSKKDGPRSSLPLHRAVLDAVVARDPVKAERAVLVLIEGAHKDIEQVLGSRRRLPRVHRP
ALPLKAA
>Mature_247_residues
MIKNVHGNTVDLLGEAIVAGRYAVGQSIPPEPVLCEQLGVSRTVVRESVKSLVAKGLIHTGPKVGTHVLPSDQWNWFDPD
VIAWQSRAGLSPEFIRDLQDLRLVVEPAAVKLAATRATDADIAEIEEAYAGMHRAVMGGGDYVTSDLRFHQGLLRASHNR
MLVQMSKALGALLRTSFEISTSKKDGPRSSLPLHRAVLDAVVARDPVKAERAVLVLIEGAHKDIEQVLGSRRRLPRVHRP
ALPLKAA

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=229, Percent_Identity=34.4978165938865, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI48994961, Length=222, Percent_Identity=30.6306306306306, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789353, Length=209, Percent_Identity=30.1435406698565, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786303, Length=206, Percent_Identity=31.0679611650485, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790032, Length=225, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790780, Length=223, Percent_Identity=26.0089686098655, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26879; Mature: 26879

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNVHGNTVDLLGEAIVAGRYAVGQSIPPEPVLCEQLGVSRTVVRESVKSLVAKGLIHT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHC
GPKVGTHVLPSDQWNWFDPDVIAWQSRAGLSPEFIRDLQDLRLVVEPAAVKLAATRATDA
CCCCCCCCCCCCCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHCHHHHEEECCCCCCC
DIAEIEEAYAGMHRAVMGGGDYVTSDLRFHQGLLRASHNRMLVQMSKALGALLRTSFEIS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
TSKKDGPRSSLPLHRAVLDAVVARDPVKAERAVLVLIEGAHKDIEQVLGSRRRLPRVHRP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCC
ALPLKAA
CCCCCCC
>Mature Secondary Structure
MIKNVHGNTVDLLGEAIVAGRYAVGQSIPPEPVLCEQLGVSRTVVRESVKSLVAKGLIHT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHC
GPKVGTHVLPSDQWNWFDPDVIAWQSRAGLSPEFIRDLQDLRLVVEPAAVKLAATRATDA
CCCCCCCCCCCCCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHCHHHHEEECCCCCCC
DIAEIEEAYAGMHRAVMGGGDYVTSDLRFHQGLLRASHNRMLVQMSKALGALLRTSFEIS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
TSKKDGPRSSLPLHRAVLDAVVARDPVKAERAVLVLIEGAHKDIEQVLGSRRRLPRVHRP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCC
ALPLKAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]